EKS-CIS-00045

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CIS-00045

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	380.8	3.9E-114	223	504	282

Status

Unreviewed

Ensembl Protein

ENSCSAVP00000007213

UniProt Accession

H2YPF5;

Protein Name

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCSAVG00000004312	ENSCSAVP00000007213	ENSCSAVT00000007306

Organism

Ciona savignyi

Functional Description

Protein Length

541

Protein Sequence
(FASTA)

VSLLVASSYA IQNISGIQPD YIDTSNGSLF DGFGMVGYRT DDNVRYISFE IEEEVFLCVC 60

TIKHGGCDEH GLCNTSGQCF AFTNSADSSN GYKAGKGCFS SAQGRMQCLK KGEVCHCCVG 120

NLCNQGLLET STTSNNYYTS VILIISVFIG FVILSIVVGL LVRRYHVKRM QELEKQREAG 180

RLEGGLRATR IGESTLADWM NSATSGSGSG LPFLVQRTMA RQITLTNCIG KGRYGAVWKG 240

MWQGEPIAVK VFASRDEQSW ARETEYNTVM LRHSNILGYI ASDMISRESD TELWLVCYYH 300

PLGSLYEYLQ RTELDHQLML QLCLSAANGL AHLHTDIVGV CGKAAIAHRD IKSKNILVKN 360

DLTCCIADLG LAVTHNSEED QINIPKNNRV GTKRYMSPEV LDETLNTSSF ECFKQADVYS 420

FGVVWEIARR CVSGGLVEEY NPPFYDVVNY DPSFEEMRKV VSVDNYRPVI PNRWSSDPSL 480

SLLSKLLRET WCKNPSNRLT IHRLAPAITK EIYPSNDMDP LLSLAPKVDE KTYARNLLEK 540

E 541

Nucleotide Sequence
(FASTA)

GTCTCTTTAC TCGTTGCGTC AAGCTATGCA ATTCAAAACA TCTCTGGTAT TCAGCCGGAT 60

TATATTGATA CAAGCAATGG ATCACTCTTT GATGGATTCG GGATGGTTGG ATACAGAACA 120

GATGATAATG TAAGATATAT TTCATTTGAG ATAGAGGAAG AGGTATTCCT GTGTGTTTGC 180

ACCATAAAAC ATGGTGGATG TGATGAACAT GGGCTCTGCA ATACTTCAGG ACAATGTTTT 240

GCGTTTACCA ACTCTGCTGA TTCAAGCAAT GGTTACAAAG CAGGCAAGGG CTGCTTCTCT 300

AGTGCACAGG GTCGAATGCA GTGTCTTAAG AAGGGGGAAG TTTGTCATTG CTGTGTTGGC 360

AACCTATGCA ACCAAGGTCT TCTAGAAACC AGCACCACAA GCAACAACTA CTACACCAGC 420

GTTATTTTGA TCATCTCTGT CTTTATTGGG TTTGTTATTC TATCGATTGT GGTTGGACTA 480

CTGGTGCGTA GATACCATGT CAAGCGAATG CAGGAATTGG AGAAACAAAG GGAAGCTGGG 540

AGGTTGGAGG GTGGGCTCCG TGCTACTCGT ATTGGGGAAA GTACCCTCGC AGATTGGATG 600

AACTCGGCCA CATCCGGATC AGGATCAGGA CTCCCGTTCC TCGTGCAGAG AACAATGGCT 660

CGGCAGATCA CCCTCACCAA CTGCATCGGC AAGGGGCGAT ACGGTGCTGT ATGGAAAGGA 720

ATGTGGCAAG GCGAACCGAT CGCGGTGAAA GTATTCGCGT CCAGAGATGA ACAATCGTGG 780

GCTCGTGAGA CAGAATACAA CACAGTGATG TTAAGACACA GCAATATACT CGGTTATATC 840

GCTTCCGACA TGATATCAAG GGAATCAGAC ACAGAGCTAT GGCTTGTATG CTACTACCAC 900

CCACTTGGAT CGTTGTATGA ATATCTTCAA CGCACCGAGT TGGACCACCA ACTGATGCTG 960

CAGCTCTGTC TCTCCGCAGC TAATGGGTTG GCACATTTGC ACACCGATAT CGTTGGAGTT 1020

TGTGGTAAAG CCGCTATAGC TCATCGCGAT ATTAAAAGCA AGAACATTCT GGTGAAAAAT 1080

GACCTGACGT GCTGCATAGC TGATCTCGGC CTCGCAGTCA CCCATAATTC AGAAGAAGAC 1140

CAAATCAATA TTCCAAAGAA CAACCGCGTT GGAACAAAGC GATACATGTC GCCTGAGGTT 1200

TTGGACGAAA CGTTAAATAC ATCGAGTTTC GAATGCTTCA AACAAGCCGA CGTCTATTCG 1260

TTCGGCGTTG TGTGGGAGAT TGCAAGACGA TGTGTGTCTG GTGGTTTAGT GGAAGAATAC 1320

AACCCCCCAT TCTATGACGT CGTCAACTAC GATCCCAGCT TCGAAGAAAT GCGGAAGGTC 1380

GTGTCAGTCG ACAATTACCG TCCCGTTATC CCCAACCGCT GGTCATCTGA CCCTTCCCTG 1440

TCATTGCTAT CGAAGCTACT TCGTGAAACT TGGTGCAAAA ACCCATCAAA CAGACTCACA 1500

ATTCATCGAT TGGCGCCAGC GATCACGAAG GAGATTTACC CGAGCAACGA TATGGACCCT 1560

CTGCTCTCTC TGGCGCCGAA AGTGGACGAA AAAACGTACG CTCGCAACCT ACTGGAGAAG 1620

GAGTGA 1626

Domain Profile

S: 1     lklleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfia  60

         ++l+++igkGryg+Vwk+ ++ge +AvK+f ++de+sw rE+e y+tv+lrh nil++ia

Q: 223   ITLTNCIGKGRYGAVWKGMWQGEPIAVKVFASRDEQSWARETE-YNTVMLRHSNILGYIA  281

         7899**************************************9.****************

S: 61    adkkeedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtk  120

         +d+ +++s tel+lv  yh+ gsL++yL+r+ ld++ +l+l+ls+a+GlahLH++ivg +

Q: 282   SDMISRESDTELWLVCYYHPLGSLYEYLQRTELDHQLMLQLCLSAANGLAHLHTDIVGVC  341

         ************************************************************

S: 121   gkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekeeldlaansqvGtkRYmaPE  180

         g  K aiaHRD+kskNilvk+dltcciaDlGLa+++++e++++++ +n++vGtkRYm+PE

Q: 342   G--KAAIAHRDIKSKNILVKNDLTCCIADLGLAVTHNSEEDQINIPKNNRVGTKRYMSPE  399

         *..*********************************************************

S: 181   vleealnlkdfeafkraDvYslgLvlWEvasRceevdeeveeyklpfeevvgsdPsleem  240

         vl+e+ln+++fe fk+aDvYs+g v+WE+a+Rc + ++ veey++pf++vv+ dPs+eem

Q: 400   VLDETLNTSSFECFKQADVYSFG-VVWEIARRCVS-GGLVEEYNPPFYDVVNYDPSFEEM  457

         ***********************.56*********.************************

S: 241   kevvvekklrPkipeawkkkealkelsklleecWdadpeaRltalrv  287

         ++vv +++ rP ip++w++++ l+ lskll+e+W ++p+ Rlt +r+

Q: 458   RKVVSVDNYRPVIPNRWSSDPSLSLLSKLLRETWCKNPSNRLTIHRL  504

         *******************************************9886

Domain Sequence
(FASTA)

ITLTNCIGKG RYGAVWKGMW QGEPIAVKVF ASRDEQSWAR ETEYNTVMLR HSNILGYIAS 60

DMISRESDTE LWLVCYYHPL GSLYEYLQRT ELDHQLMLQL CLSAANGLAH LHTDIVGVCG 120

KAAIAHRDIK SKNILVKNDL TCCIADLGLA VTHNSEEDQI NIPKNNRVGT KRYMSPEVLD 180

ETLNTSSFEC FKQADVYSFG VVWEIARRCV SGGLVEEYNP PFYDVVNYDP SFEEMRKVVS 240

VDNYRPVIPN RWSSDPSLSL LSKLLRETWC KNPSNRLTIH RL 282

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0004675	; F:transmembrane receptor protein serine/threonine kinase activity
GO:0007178	; P:transmembrane receptor protein serine/threonine kinase signaling pathway

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.
IPR003605	; TGF_beta_rcpt_GS.

Pfam

PF00069	; Pkinase; 1.
PF08515	; TGF_beta_GS; 1.

SMARTs

SM00467

; GS; 1.

Prosites

PS51256	; GS; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013