EKS-CIS-00068

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CIS-00068

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	343.0	1.2E-102	4	292	289

Status

Unreviewed

Ensembl Protein

ENSCSAVP00000008425

UniProt Accession

H2YSW5;

Protein Name

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCSAVG00000005004	ENSCSAVP00000008425	ENSCSAVT00000008534

Organism

Ciona savignyi

Functional Description

Protein Length

343

Protein Sequence
(FASTA)

MEQYHILGRI GEGAHGIVFK AKHIESGEVV ALKKVPLRKI EDGIPNQALR EIKALQEIGG 60

DSEEAQNVVK LHDVFPHGTG FVLVFEYMLS DLSEVIRNSE RPLTESQIKS YMMMLLKGVA 120

FCHQNNIMHR DLKPANLLIS STGHLKIADF GLARVFENNT DRLYSHQVAT RWYRSPELLY 180

GARKYDEGVD LWAVGCIFGE MLNNSPLFPG ENDIEQLCCV LRVLGTPNEA IWPGMSMLPD 240

YNKITFPENP PIPLEEIVPD ASEDALDLLK KFLLYPSNER IAAMEALLHP YFFTEPLPAH 300

HSELPIPQRA RKSSRHRSNF KEYDIDVPIE QSCIDPSLIA EFA 343

Nucleotide Sequence
(FASTA)

ATGGAACAAT ACCACATATT AGGTCGTATA GGGGAAGGAG CGCATGGGAT TGTCTTTAAA 60

GCAAAGCATA TTGAGAGTGG AGAGGTTGTT GCACTGAAGA AGGTCCCACT TCGGAAGATC 120

GAAGATGGGA TCCCCAACCA AGCGCTGAGG GAGATCAAAG CTTTGCAGGA GATTGGAGGC 180

GATAGTGAAG AAGCACAGAA TGTTGTGAAG CTACACGATG TGTTCCCACA CGGGACTGGA 240

TTTGTGCTTG TATTCGAGTA CATGTTATCC GATCTATCGG AGGTGATCCG GAACTCTGAA 300

CGACCTCTTA CCGAGAGCCA GATCAAGAGT TACATGATGA TGCTGCTAAA GGGGGTGGCT 360

TTCTGTCATC AAAATAACAT CATGCATCGT GATTTAAAGC CAGCAAATTT GTTAATCAGT 420

TCAACTGGTC ATCTGAAGAT TGCCGACTTT GGGCTTGCTA GGGTTTTCGA GAACAATACC 480

GACAGATTGT ACAGTCATCA AGTTGCTACA AGATGGTATC GCTCCCCAGA ATTATTGTAC 540

GGGGCACGGA AGTATGATGA AGGGGTTGAT TTGTGGGCAG TGGGCTGCAT ATTTGGTGAG 600

ATGCTCAACA ACTCTCCATT ATTTCCGGGT GAAAACGATA TCGAGCAATT ATGCTGTGTT 660

CTCCGTGTGC TCGGGACACC AAACGAAGCG ATATGGCCCG GTATGTCTAT GCTTCCCGAT 720

TATAACAAGA TCACCTTCCC GGAAAATCCT CCGATCCCAC TGGAGGAGAT TGTTCCGGAT 780

GCATCCGAAG ACGCCTTGGA TTTGCTGAAG AAGTTTCTTC TTTACCCGTC GAACGAGAGA 840

ATAGCAGCAA TGGAAGCGCT ACTTCACCCC TACTTCTTCA CCGAGCCCCT CCCCGCGCAC 900

CACTCCGAAC TTCCGATCCC GCAACGAGCT CGAAAATCCT CCCGCCATCG ATCAAACTTC 960

AAGGAATACG ACATTGACGT CCCGATTGAG CAAAGCTGTA TCGACCCAAG TCTAATAGCC 1020

GAGTTCGCT 1029

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkel.....  55

         y+ l +igeG++g v+kak+ e+gevvAlKk+ l k ++g+p +alrEi+ l+e+

Q: 4     YHILGRIGEGAHGIVFKAKHIESGEVVALKKVPLRKIEDGIPNQALREIKALQEIggdse  63

         778999************************************************999999

S: 56    khknivkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglay  115

         + +n+vkL++v+  + + ++Lvfe++ +dL+++++++++  l+++++ks++++ll+g+a+

Q: 64    EAQNVVKLHDVFP-HGTGFVLVFEYMLSDLSEVIRNSER-PLTESQIKSYMMMLLKGVAF  121

         99***********.99*********************99.********************

S: 116   lHsnkilHRDlKpqNlLiskegklklaDfGlarafssplkt.ytkevvTlwYraPelLlg  174

         +H+n+i+HRDlKp+NlLis++g+lk+aDfGlar f++++++ y+++v T+wYr+PelL+g

Q: 122   CHQNNIMHRDLKPANLLISSTGHLKIADFGLARVFENNTDRlYSHQVATRWYRSPELLYG  181

         ***********************************8888755******************

S: 175   akeYstavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpey  234

         a++Y++ vD+W+vgci+ e+l+++plf+g+++i+ql  ++++lgtp+e++wp++s lp+y

Q: 182   ARKYDEGVDLWAVGCIFGEMLNNSPLFPGENDIEQLCCVLRVLGTPNEAIWPGMSMLPDY  241

         ************************************************************

S: 235   k.ksfpkkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         +  +fp++++  l+e v++++e+aldll+k+l +  ++Ri a eal h+yf

Q: 242   NkITFPENPPIPLEEIVPDASEDALDLLKKFLLYPSNERIAAMEALLHPYF  292

         *889***9999***************************************9

Domain Sequence
(FASTA)

YHILGRIGEG AHGIVFKAKH IESGEVVALK KVPLRKIEDG IPNQALREIK ALQEIGGDSE 60

EAQNVVKLHD VFPHGTGFVL VFEYMLSDLS EVIRNSERPL TESQIKSYMM MLLKGVAFCH 120

QNNIMHRDLK PANLLISSTG HLKIADFGLA RVFENNTDRL YSHQVATRWY RSPELLYGAR 180

KYDEGVDLWA VGCIFGEMLN NSPLFPGEND IEQLCCVLRV LGTPNEAIWP GMSMLPDYNK 240

ITFPENPPIP LEEIVPDASE DALDLLKKFL LYPSNERIAA MEALLHPYF 289

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013