EKS-CIS-00064

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CIS-00064

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	365.1	2.3E-109	33	317	285

Status

Unreviewed

Ensembl Protein

ENSCSAVP00000008476

UniProt Accession

H2YT16;

Protein Name

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCSAVG00000005035	ENSCSAVP00000008476	ENSCSAVT00000008585

Organism

Ciona savignyi

Functional Description

Protein Length

354

Protein Sequence
(FASTA)

IMEDDELVSL STGKKFKIPE NDRYGVCRDV TTFEKLNRIG EGTYGIVYRA RDKITKQIVA 60

LKKVRTENEK EGISISSIRE ITLLLNLKHK NIVELKEVVV GQRLDSIFLV MEYCEQDLAN 120

LLDNMTTPFS EAQVKCITLQ LLRGLAFLHN SFIVHRDLKV SNLLMTDGGI LKIADFGLAR 180

LYSIPQTSMT PRVVTLWYRA PELLFGSTKY TKSVDIWAAG CILAELLAHK PTFPGKSEIE 240

MIELLIQMLG SPSEEIWPGF SELPAIKSVY LKNQPYNNLK HRFPWVSEAG LRLLNLMLLY 300

DPAKRATAEE CIEISYFKEN PHPCGPEMMP TFPHHRNKRK SSTEHKMVPS KRKE 354

Nucleotide Sequence
(FASTA)

ATAATGGAAG ACGACGAACT GGTATCATTA TCGACTGGAA AAAAGTTTAA AATACCTGAA 60

AATGACCGAT ACGGGGTATG TAGAGACGTA ACAACTTTCG AGAAGCTGAA TAGAATCGGC 120

GAAGGAACGT ACGGGATTGT CTACCGCGCA CGCGATAAAA TAACCAAACA AATTGTTGCC 180

CTGAAAAAAG TACGAACCGA AAATGAAAAG GAAGGTATTT CAATTAGCAG TATTCGTGAG 240

ATTACTTTGC TTTTGAACTT GAAGCACAAG AATATAGTCG AATTAAAAGA AGTGGTGGTT 300

GGACAGCGGC TGGACAGCAT TTTTCTTGTA ATGGAGTACT GCGAACAGGA TCTTGCTAAT 360

TTATTGGATA ATATGACAAC ACCATTCTCA GAGGCCCAGG TCAAATGTAT AACTTTGCAA 420

CTTTTGCGAG GTCTAGCTTT CCTCCATAAC AGCTTCATTG TGCACAGAGA TTTAAAAGTT 480

TCGAACTTAC TTATGACCGA TGGTGGGATA CTTAAAATTG CCGATTTTGG TTTGGCGCGA 540

CTTTACTCTA TCCCACAAAC CAGTATGACA CCTCGTGTGG TGACACTGTG GTACAGAGCA 600

CCGGAGTTAC TATTCGGTTC CACAAAATAC ACGAAAAGTG TTGATATATG GGCAGCGGGG 660

TGCATTTTAG CCGAACTACT TGCTCATAAA CCCACTTTTC CTGGCAAAAG CGAGATTGAG 720

ATGATAGAGT TGTTGATTCA AATGCTCGGT TCACCCAGCG AAGAAATTTG GCCCGGGTTT 780

TCCGAGCTCC CAGCTATAAA GTCTGTCTAC TTGAAAAATC AGCCGTACAA TAATCTTAAG 840

CACCGGTTTC CATGGGTTTC TGAGGCAGGG CTCCGGCTAC TGAACCTTAT GCTTCTATAC 900

GACCCTGCCA AACGAGCTAC CGCAGAAGAA TGCATAGAAA TATCATATTT TAAAGAAAAT 960

CCACACCCGT GTGGGCCCGA AATGATGCCA ACTTTTCCGC ACCATAGAAA TAAAAGAAAA 1020

TCGAGCACAG AACATAAAAT GGTTCCTTCG AAACGCAAAG AG 1062

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         +ekl++igeGtyg vy+a+dk t+++vAlKk+r+e+ekeg++i+++rEi+ll +lkhkni

Q: 33    FEKLNRIGEGTYGIVYRARDKITKQIVALKKVRTENEKEGISISSIREITLLLNLKHKNI  92

         89**********************************************************

S: 61    vkLlevvakdk.kklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsn  119

         v+L+evv+ ++ ++++Lv+e++eqdL++ll+++++  +s+++vk ++lqll+gla+lH++

Q: 93    VELKEVVVGQRlDSIFLVMEYCEQDLANLLDNMTT-PFSEAQVKCITLQLLRGLAFLHNS  151

         ********6666**********************9.************************

S: 120   kilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYs  179

          i+HRDlK +NlL+++ g+lk+aDfGlar +s p+ ++t++vvTlwYraPelL+g+++Y+

Q: 152   FIVHRDLKVSNLLMTDGGILKIADFGLARLYSIPQTSMTPRVVTLWYRAPELLFGSTKYT  211

         ************************************************************

S: 180   tavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ksf  238

         ++vDiW++gcilaell++kp f+gksei+ +e ++++lg+pse++wp++s+lp +k   +

Q: 212   KSVDIWAAGCILAELLAHKPTFPGKSEIEMIELLIQMLGSPSEEIWPGFSELPAIKsVYL  271

         ********************************************************7777

S: 239   pkkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         +++++++lk++++ ++e++l+ll+ +l +dp+kR +a+e+++ +yf

Q: 272   KNQPYNNLKHRFPWVSEAGLRLLNLMLLYDPAKRATAEECIEISYF  317

         888888***********************************99998

Domain Sequence
(FASTA)

FEKLNRIGEG TYGIVYRARD KITKQIVALK KVRTENEKEG ISISSIREIT LLLNLKHKNI 60

VELKEVVVGQ RLDSIFLVME YCEQDLANLL DNMTTPFSEA QVKCITLQLL RGLAFLHNSF 120

IVHRDLKVSN LLMTDGGILK IADFGLARLY SIPQTSMTPR VVTLWYRAPE LLFGSTKYTK 180

SVDIWAAGCI LAELLAHKPT FPGKSEIEMI ELLIQMLGSP SEEIWPGFSE LPAIKSVYLK 240

NQPYNNLKHR FPWVSEAGLR LLNLMLLYDP AKRATAEECI EISYF 285

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013