EKS-CIS-00196

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CIS-00196

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/PKG	492.0	3.2E-148	368	626	259

Status

Unreviewed

Ensembl Protein

ENSCSAVP00000009483

UniProt Accession

H2YVX3;

Protein Name

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCSAVG00000005580	ENSCSAVP00000009486	ENSCSAVT00000009603
ENSCSAVG00000005580	ENSCSAVP00000009487	ENSCSAVT00000009604
ENSCSAVG00000005580	ENSCSAVP00000009488	ENSCSAVT00000009605
ENSCSAVG00000005580	ENSCSAVP00000009489	ENSCSAVT00000009606
ENSCSAVG00000005580	ENSCSAVP00000009483	ENSCSAVT00000009600
ENSCSAVG00000005580	ENSCSAVP00000009484	ENSCSAVT00000009601
ENSCSAVG00000005580	ENSCSAVP00000009490	ENSCSAVT00000009607
ENSCSAVG00000005580	ENSCSAVP00000009485	ENSCSAVT00000009602

Organism

Ciona savignyi

Functional Description

Protein Length

678

Protein Sequence
(FASTA)

IMDYQYDLRH KVLLKDERIR ELECMLAEKD EEIEELKAKL DKFQSIFPTA TQQRHLGTMG 60

VGVPRTRRAQ GISAEPNLML NDPSSAEIQT YAKSENTKTL IRGAILENDF MKHLEDCQIE 120

EIVDCMYPVE YSNGSCIIKE GDVGSLVYVL EDGKVAVTKA GAHLCNMGAG KVFGELAILY 180

NCTRTATVKA TTHVRLWAID RHCFQAIMMR TGLLKHSEYL EFLTSVPTFS GLGEDLLRRI 240

VDVMEECHFD YGDYIIRQGA IGDTFYIISK GNVEVTKRKS ASSESVVIRK LAKGDWFGER 300

ALQGEDLRTA NVVVEDREGA TCLVIDRQSF TQLIGDLDSV KQRKYDEVPE LSKKSDGFYD 360

DLILEDFTAI DTLGVGGFGR VELVELKSDP AKTYAMKVLK KRHIVDTRQQ EHIKNEKVIM 420

MDCNSDFIVK MYRTFRDTKY IYMLLECCLG GELWTVLRDK GHFDDSAARF YTACVVEAFT 480

YMHARGIIYR DLKPENLLLD TRGYAKLVDF GFAKRIGFSR KTWTFCGTPE YVAPEIILNK 540

GHDLSADYWS LGILMFELMT GSPPFSGSDP MKTYNQILKG IDMIEFPKKI SKNAQSLIRK 600

LCRDNPSERL GNQRNGIKDI QKHKWFDGFH WIGLRKGTMA PPTKPQVTSS SDSSNFDKFP 660

EDDDTPPPDD LSGWDNDF 678

Nucleotide Sequence
(FASTA)

ATCATGGATT ACCAATACGA TCTCCGGCAC AAAGTTCTCC TCAAAGATGA AAGGATCAGG 60

GAACTGGAAT GCATGCTTGC TGAGAAAGAC GAGGAAATTG AAGAACTTAA AGCAAAGTTG 120

GACAAATTTC AGTCGATTTT TCCGACTGCT ACACAACAGC GCCACCTTGG GACGATGGGT 180

GTCGGAGTTC CACGAACACG GAGGGCGCAA GGGATCAGCG CAGAACCGAA CTTAATGCTT 240

AACGATCCGT CATCAGCTGA AATTCAGACT TATGCGAAAT CAGAAAATAC GAAAACTCTG 300

ATCCGAGGGG CGATTCTAGA GAACGATTTT ATGAAGCACT TGGAAGATTG CCAGATCGAA 360

GAAATAGTTG ATTGCATGTA CCCGGTTGAA TACAGTAATG GAAGTTGCAT CATAAAGGAA 420

GGCGACGTCG GGTCGTTGGT CTACGTCCTT GAAGATGGCA AAGTTGCCGT AACGAAGGCT 480

GGTGCTCATC TATGCAATAT GGGAGCTGGT AAAGTGTTCG GAGAACTCGC CATTCTGTAC 540

AACTGCACCA GGACCGCAAC TGTCAAAGCT ACAACACACG TACGATTATG GGCCATAGAC 600

CGTCATTGTT TCCAGGCAAT AATGATGAGA ACAGGTCTTC TAAAGCATTC GGAATATCTA 660

GAGTTTCTCA CCAGTGTACC CACTTTCTCC GGTCTCGGAG AGGACCTGCT AAGACGAATT 720

GTGGACGTTA TGGAAGAGTG CCACTTCGAT TATGGTGACT ACATTATCCG CCAGGGGGCG 780

ATAGGGGACA CCTTCTACAT CATTAGCAAA GGCAACGTTG AAGTCACTAA GCGCAAGAGC 840

GCCTCTAGCG AATCTGTTGT GATCAGGAAG TTGGCTAAAG GAGATTGGTT TGGCGAGCGA 900

GCTCTACAAG GGGAGGATCT ACGCACAGCG AACGTTGTTG TTGAAGACAG AGAAGGAGCT 960

ACGTGTCTCG TGATTGACAG ACAGTCGTTC ACCCAACTGA TTGGGGATCT GGACAGCGTA 1020

AAACAACGAA AGTATGACGA AGTACCGGAA CTGAGTAAGA AGTCCGACGG ATTCTACGAC 1080

GATTTGATCC TCGAAGACTT CACTGCGATT GATACACTAG GCGTCGGAGG ATTCGGCCGT 1140

GTGGAGTTGG TGGAGCTAAA GAGCGACCCA GCGAAAACGT ACGCCATGAA GGTGCTGAAG 1200

AAGCGACACA TAGTGGACAC TCGACAGCAG GAACATATTA AGAACGAGAA AGTTATCATG 1260

ATGGATTGCA ACTCAGATTT CATTGTCAAA ATGTACCGCA CATTCCGGGA CACGAAGTAC 1320

ATCTACATGC TGCTTGAATG CTGTCTTGGG GGAGAGCTCT GGACAGTGTT GCGAGACAAA 1380

GGTCATTTCG ACGATTCAGC CGCTCGATTC TACACCGCAT GCGTAGTCGA GGCATTCACG 1440

TACATGCACG CACGTGGGAT CATATACAGA GATCTGAAGC CGGAAAATCT GCTTTTGGAT 1500

ACAAGAGGAT ATGCGAAACT GGTGGATTTC GGCTTTGCCA AACGGATTGG TTTCAGTCGG 1560

AAAACGTGGA CATTTTGCGG AACGCCGGAA TACGTAGCGC CGGAAATCAT TCTAAATAAA 1620

GGTCACGACC TTTCAGCGGA TTACTGGTCG CTGGGGATCC TGATGTTTGA GCTGATGACC 1680

GGAAGTCCCC CGTTTTCCGG CTCCGACCCG ATGAAGACTT ACAACCAAAT ACTCAAGGGA 1740

ATTGACATGA TCGAATTTCC CAAGAAGATA TCAAAGAATG CACAAAGTCT TATACGGAAA 1800

CTATGCAGGG ACAATCCATC TGAACGGCTG GGAAATCAGA GGAACGGAAT CAAAGACATC 1860

CAGAAGCACA AGTGGTTCGA TGGGTTCCAT TGGATTGGAT TGAGGAAAGG GACAATGGCT 1920

CCACCTACTA AACCCCAGGT CACCAGTTCC TCCGATTCGT CAAACTTCGA CAAATTCCCA 1980

GAGGATGACG ACACGCCGCC CCCGGATGAC CTTTCCGGAT GGGACAATGA TTTCTAA 2037

Domain Profile

S: 2     kviatlgvggfgrvelvkvksdeskafalkilkkkhivdtkqqehvlsekrileeaksdf  61

           i+tlgvggfgrvelv++ksd +k++a+k+lkk+hivdt+qqeh+ +ek i+++++sdf

Q: 368   TAIDTLGVGGFGRVELVELKSDPAKTYAMKVLKKRHIVDTRQQEHIKNEKVIMMDCNSDF  427

         579*********************************************************

S: 62    ivklyrtfkdekyvyllleaclggelwtilrdrgsfddktakfivacvvealeylhskni  121

         ivk+yrtf+d ky+y+lle+clggelwt+lrd+g+fdd++a+f++acvvea+ y+h+++i

Q: 428   IVKMYRTFRDTKYIYMLLECCLGGELWTVLRDKGHFDDSAARFYTACVVEAFTYMHARGI  487

         ************************************************************

S: 122   iyrdlkpenllldeegylklvdfgfakklksgkktwtfcgtpeyvapeiilnkghdlsvd  181

         iyrdlkpenllld++gy+klvdfgfak+++ ++ktwtfcgtpeyvapeiilnkghdls+d

Q: 488   IYRDLKPENLLLDTRGYAKLVDFGFAKRIGFSRKTWTFCGTPEYVAPEIILNKGHDLSAD  547

         ************************************************************

S: 182   ywalgilvyelltgkppfsgvdplktynlilkgidklelprkitkeaedlikklcrdnpa  241

         yw+lgil++el+tg+ppfsg+dp+ktyn+ilkgid++e+p+ki+k+a++li+klcrdnp+

Q: 548   YWSLGILMFELMTGSPPFSGSDPMKTYNQILKGIDMIEFPKKISKNAQSLIRKLCRDNPS  607

         ************************************************************

S: 242   erlgylkggikdikkhkwf  260

         erlg++++gikdi+khkwf

Q: 608   ERLGNQRNGIKDIQKHKWF  626

         ******************9

Domain Sequence
(FASTA)

TAIDTLGVGG FGRVELVELK SDPAKTYAMK VLKKRHIVDT RQQEHIKNEK VIMMDCNSDF 60

IVKMYRTFRD TKYIYMLLEC CLGGELWTVL RDKGHFDDSA ARFYTACVVE AFTYMHARGI 120

IYRDLKPENL LLDTRGYAKL VDFGFAKRIG FSRKTWTFCG TPEYVAPEII LNKGHDLSAD 180

YWSLGILMFE LMTGSPPFSG SDPMKTYNQI LKGIDMIEFP KKISKNAQSL IRKLCRDNPS 240

ERLGNQRNGI KDIQKHKWF 259

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR018490	; cNMP-bd-like.
IPR018488	; cNMP-bd_CS.
IPR000595	; cNMP-bd_dom.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR014710	; RmlC-like_jellyroll.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00027	; cNMP_binding; 2.
PF00069	; Pkinase; 1.

SMARTs

SM00100	; cNMP; 2.
SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00888	; CNMP_BINDING_1; 2.
PS00889	; CNMP_BINDING_2; 2.
PS50042	; CNMP_BINDING_3; 2.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013