EKS-CIS-00222

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CIS-00222

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/MAPK	397.5	3.0E-119	24	306	283

Status

Unreviewed

Ensembl Protein

ENSCSAVP00000010099

UniProt Accession

H2YXP0;

Protein Name

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCSAVG00000005955	ENSCSAVP00000010099	ENSCSAVT00000010221
ENSCSAVG00000005955	ENSCSAVP00000010100	ENSCSAVT00000010222
ENSCSAVG00000005955	ENSCSAVP00000010102	ENSCSAVT00000010224
ENSCSAVG00000005955	ENSCSAVP00000010101	ENSCSAVT00000010223
ENSCSAVG00000005955	ENSCSAVP00000010097	ENSCSAVT00000010219
ENSCSAVG00000005955	ENSCSAVP00000010098	ENSCSAVT00000010220

Organism

Ciona savignyi

Functional Description

Protein Length

364

Protein Sequence
(FASTA)

KDTANAEFYT LQVSDSVFTV LKRYQSLKPI GSGAQGMVCA AHDTVLGQNV AIKKLSRPFQ 60

NPTHAKRAYR ELVLMRAVNH KNIIGLLNVF SPQSTYEEFS HVYLVMELMD ASLCQVIQMD 120

LDHERLSYLL YQLLCGIKHL HSAGIIHRDL KPSNIVVRSD CTLKILDFGL ARTAGGSFMM 180

TPYVVTRYYR APEVILGMGY QEVVDIWSVG CIFGEMIRGQ VLFPGTDHID QWNKITEQLG 240

TPSQDFINKL QPTVRNYVLN RPMQRGHPIH RLFPDTTQAR DLLAKMLVVD PIGRITVDEA 300

LQHPYIKIWY DPSEVEGPGP KVDGAAIDEV DYSVEKWKEV IWKEVELWDS VDTTVPNPIL 360

PLSS 364

Nucleotide Sequence
(FASTA)

AAAGACACAG CAAACGCAGA ATTCTACACT CTACAAGTGT CCGACTCGGT GTTCACAGTT 60

CTTAAAAGAT ATCAGAGTTT GAAACCAATT GGCTCTGGTG CGCAGGGAAT GGTATGTGCA 120

GCACATGACA CAGTTCTTGG ACAGAATGTG GCAATAAAAA AACTTAGTCG ACCTTTTCAA 180

AATCCAACCC ATGCGAAAAG AGCATACAGG GAACTGGTAT TAATGCGCGC TGTCAATCAC 240

AAGAATATCA TTGGTTTATT GAACGTTTTT TCCCCACAAT CGACATATGA AGAGTTTTCT 300

CATGTATATT TGGTGATGGA ACTTATGGAT GCGAGCTTGT GTCAGGTAAT TCAAATGGAC 360

CTTGACCATG AGCGACTTTC CTACCTACTA TACCAGTTAT TGTGCGGCAT CAAGCATTTG 420

CATTCAGCCG GAATTATACA CAGAGACTTA AAGCCTTCCA ACATAGTTGT ACGGTCGGAC 480

TGCACACTGA AAATTCTTGA TTTCGGATTA GCCAGAACCG CAGGAGGTTC TTTTATGATG 540

ACACCCTATG TAGTTACCCG TTATTACAGA GCACCAGAGG TGATTCTGGG CATGGGTTAT 600

CAAGAGGTGG TGGACATATG GTCAGTTGGA TGCATTTTTG GCGAAATGAT CAGAGGCCAG 660

GTATTGTTTC CTGGTACTGA CCATATTGAC CAGTGGAACA AAATTACAGA ACAACTCGGC 720

ACTCCTTCAC AGGACTTCAT CAACAAACTG CAGCCGACTG TGCGAAACTA TGTCCTGAAT 780

CGACCCATGC AGCGTGGACA CCCGATCCAC AGATTGTTCC CTGACACAAC ACAAGCGCGG 840

GACCTGCTTG CTAAGATGCT TGTAGTTGAT CCTATTGGGA GGATCACAGT AGATGAGGCT 900

CTTCAGCACC CTTATATTAA GATTTGGTAT GATCCCAGCG AGGTTGAAGG TCCTGGTCCC 960

AAAGTGGATG GTGCTGCAAT CGACGAAGTG GATTACTCGG TTGAAAAGTG GAAGGAAGTG 1020

ATTTGGAAAG AAGTTGAGCT TTGGGACTCG GTGGACACAA CCGTGCCGAA CCCTATTTTG 1080

CCGCTGTCCA GC 1092

Domain Profile

S: 1     yeslkplgeGaygvvvsavdkrteervaikklsrpfqketsakrtlRElkllkelkheNi  60

         y+slkp+g+Ga+g+v++a d+  +++vaikklsrpfq+ t+akr++REl l++ ++h+Ni

Q: 24    YQSLKPIGSGAQGMVCAAHDTVLGQNVAIKKLSRPFQNPTHAKRAYRELVLMRAVNHKNI  83

         899*********************************************************

S: 61    iklldvftpeeeleelkdvYlvtelmetdLkkviksqklsdehiklllyqilrglkylHs  120

         i ll+vf p++++ee+++vYlv+elm++ L++vi+++ l++e++++llyq+l+g+k+lHs

Q: 84    IGLLNVFSPQSTYEEFSHVYLVMELMDASLCQVIQMD-LDHERLSYLLYQLLCGIKHLHS  142

         ************************************9.**********************

S: 121   anviHrDlKPsNllvnedcelkildFGlarsadkekekklteyvatrwYraPeillslke  180

         a++iHrDlKPsN++v +dc+lkildFGlar+a  + +  +t+yv+tr+YraPe++l  +

Q: 143   AGIIHRDLKPSNIVVRSDCTLKILDFGLARTAGGSFM--MTPYVVTRYYRAPEVILG-MG  199

         *********************************9976..*****************9.99

S: 181   ytkavDiWsvGCIlaElltgkplfpgkdeidqlekilevlgtpseeflkkieseearnyi  240

         y++ vDiWsvGCI++E+++g++lfpg+d+idq++ki+e+lgtps++f++k++  ++rny+

Q: 200   YQEVVDIWSVGCIFGEMIRGQVLFPGTDHIDQWNKITEQLGTPSQDFINKLQP-TVRNYV  258

         *****************************************************.5*****

S: 241   kslpkkkkkdfeelfpkaseealdLleklLvldpdkRisveeaLehpYl  289

          ++p+++ +++++lfp++ ++a+dLl k+Lv+dp  Ri+v+eaL+hpY+

Q: 259   LNRPMQRGHPIHRLFPDT-TQARDLLAKMLVVDPIGRITVDEALQHPYI  306

         ****************86.689**************************7

Domain Sequence
(FASTA)

YQSLKPIGSG AQGMVCAAHD TVLGQNVAIK KLSRPFQNPT HAKRAYRELV LMRAVNHKNI 60

IGLLNVFSPQ STYEEFSHVY LVMELMDASL CQVIQMDLDH ERLSYLLYQL LCGIKHLHSA 120

GIIHRDLKPS NIVVRSDCTL KILDFGLART AGGSFMMTPY VVTRYYRAPE VILGMGYQEV 180

VDIWSVGCIF GEMIRGQVLF PGTDHIDQWN KITEQLGTPS QDFINKLQPT VRNYVLNRPM 240

QRGHPIHRLF PDTTQARDLL AKMLVVDPIG RITVDEALQH PYI 283

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004707	; F:MAP kinase activity
GO:0000165	; P:MAPK cascade

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR003527	; MAP_kinase_CS.
IPR008351	; MAPK_JNK.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 2.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS01351	; MAPK; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR01772

; JNKMAPKINASE.

Created Date

20-Feb-2013