EKS-CIS-00183

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CIS-00183

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/NDR	475.7	5.0E-143	79	378	300

Status

Unreviewed

Ensembl Protein

ENSCSAVP00000010566

UniProt Accession

H2YZ01;

Protein Name

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCSAVG00000006212	ENSCSAVP00000010568	ENSCSAVT00000010696
ENSCSAVG00000006212	ENSCSAVP00000010567	ENSCSAVT00000010695
ENSCSAVG00000006212	ENSCSAVP00000010566	ENSCSAVT00000010694
ENSCSAVG00000006212	ENSCSAVP00000010565	ENSCSAVT00000010693
ENSCSAVG00000006212	ENSCSAVP00000010564	ENSCSAVT00000010692
ENSCSAVG00000006212	ENSCSAVP00000010563	ENSCSAVT00000010691
ENSCSAVG00000006212	ENSCSAVP00000010562	ENSCSAVT00000010690
ENSCSAVG00000006212	ENSCSAVP00000010561	ENSCSAVT00000010689

Organism

Ciona savignyi

Functional Description

Protein Length

448

Protein Sequence
(FASTA)

SLSTHTLEKV KKAKVTIETF YSNLLNQQIE REGRMQILEK SMQQEGLSVD QCEKKRVQHA 60

QKETEFLRLK RTRLGLGDFE MLKVIGRGAF GEVRLVQKKD TGHIYAMKML RKKDMMDKEQ 120

VAHVRAERDI LVEAENPWVV KMFYSFQDTY NLYLIMEFLP GGDMMTLLIF NSKTDTLTEE 180

QTQFYMAESV LAINSIHELG FIHRDIKPDN LLIDARGHVK LSDFGLCTGL KKAHSTDYYR 240

DLTQAQPIDF TTRPLNANDS RRKAETWKSK RRKLAYSTVG TPDYIAPEVF QQSGYNLSCD 300

WWSLGVIMYE SLIGYPPFCS ESPQETYRKV MNWRNTLVFP DEVPISDIAR NLILSLCTDP 360

DKRLGFPEVE SLKEHAFFKG VDWIHIRDRP AAITMAIKSL TDTSNFDEFP DADLKLGNTI 420

KYNPLPHPNG DWVFINYTYK RFEGLTQR 448

Nucleotide Sequence
(FASTA)

TCCTTAAGCA CTCACACTTT GGAGAAGGTG AAAAAAGCGA AAGTCACGAT CGAGACGTTC 60

TACTCAAATT TGCTGAATCA GCAAATTGAG AGGGAAGGCC GGATGCAGAT ATTGGAGAAA 120

TCAATGCAAC AAGAGGGCTT GTCTGTTGAT CAGTGCGAAA AGAAGAGAGT GCAGCATGCT 180

CAGAAAGAAA CCGAGTTTCT ACGGTTAAAA CGGACAAGAC TGGGTCTCGG AGATTTTGAG 240

ATGCTCAAAG TTATCGGACG TGGTGCTTTT GGGGAGGTAC GACTGGTCCA GAAGAAAGAC 300

ACCGGCCACA TCTACGCAAT GAAGATGCTC AGGAAAAAAG ACATGATGGA CAAGGAACAG 360

GTGGCCCATG TTCGAGCGGA ACGGGATATT CTAGTGGAAG CTGAGAATCC ATGGGTGGTG 420

AAGATGTTCT ATTCATTCCA GGACACATAC AACCTCTACC TTATCATGGA GTTTCTTCCT 480

GGAGGAGACA TGATGACTCT ACTTATTTTT AATTCTAAAA CAGACACTCT AACTGAAGAG 540

CAGACCCAGT TCTACATGGC AGAATCAGTT CTGGCAATCA ACTCAATACA TGAGCTTGGA 600

TTCATACACA GGGATATCAA ACCAGACAAC TTACTAATAG ACGCGAGGGG ACATGTAAAG 660

TTATCCGACT TCGGATTATG CACAGGATTA AAGAAAGCTC ACAGCACTGA TTATTACCGA 720

GATCTTACCC AGGCACAACC TATAGATTTC ACCACCCGCC CCCTAAACGC GAACGACTCT 780

CGACGGAAAG CTGAAACTTG GAAGAGCAAA CGTCGAAAGC TTGCGTACTC CACTGTTGGA 840

ACCCCGGATT ATATCGCCCC CGAAGTATTC CAACAATCAG GGTACAACTT AAGTTGTGAC 900

TGGTGGTCGT TGGGGGTGAT AATGTACGAA TCGCTTATCG GTTATCCCCC TTTTTGCTCC 960

GAGAGCCCTC AAGAGACATA CCGGAAGGTG ATGAATTGGA GGAACACCCT GGTGTTCCCT 1020

GACGAGGTCC CGATATCGGA CATCGCTCGT AATCTCATCC TCTCCCTCTG TACCGACCCG 1080

GATAAGAGGT TGGGCTTCCC TGAAGTCGAA TCTTTGAAGG AGCACGCATT CTTCAAAGGG 1140

GTGGATTGGA TCCATATACG TGATAGGCCG GCAGCAATCA CGATGGCGAT AAAGAGCCTC 1200

ACCGACACGT CCAACTTCGA CGAGTTTCCT GACGCTGATC TTAAATTAGG AAATACCATA 1260

AAATATAATC CCTTACCCCA CCCTAACGGC GATTGGGTTT TCATCAACTA CACGTACAAG 1320

CGTTTCGAGG GGTTAACCCA ACGA 1344

Domain Profile

S: 1     feklkvigkGafGevrlvrkkdtkevyalkilrkkdllkknqvahvkaerdilaeadsew  60

         fe+lkvig+GafGevrlv+kkdt+++ya+k+lrkkd++ k+qvahv+aerdil+ea+++w

Q: 79    FEMLKVIGRGAFGEVRLVQKKDTGHIYAMKMLRKKDMMDKEQVAHVRAERDILVEAENPW  138

         89**********************************************************

S: 61    vvklyysfqdkenlylvmeylPGGdlmtlli...kkeilkeelarfyiaelvlavesvhk  117

         vvk++ysfqd+ nlyl+me+lPGGd+mtlli   k+++l+ee+++fy+ae vla++s+h+

Q: 139   VVKMFYSFQDTYNLYLIMEFLPGGDMMTLLIfnsKTDTLTEEQTQFYMAESVLAINSIHE  198

         ******************************8766899***********************

S: 118   lGfihrdlkPdnllidakGhikltdfGlctGlkkthrseyykelekakeddleaseelkv  177

         lGfihrd+kPdnllida+Gh+kl+dfGlctGlkk+h+++yy++l++a++ d+ +    ++

Q: 199   LGFIHRDIKPDNLLIDARGHVKLSDFGLCTGLKKAHSTDYYRDLTQAQPIDFTTRPL-NA  257

         ****************************************************66554.44

S: 178   lerrkk....kknrrllayslvGtpdyiapevlekkgynklcdwWslGvilyemlvGypP  233

          ++r+k    k +rr lays+vGtpdyiapev++++gyn +cdwWslGvi+ye+l+GypP

Q: 258   NDSRRKaetwKSKRRKLAYSTVGTPDYIAPEVFQQSGYNLSCDWWSLGVIMYESLIGYPP  317

         5555555899**************************************************

S: 234   flaetpqetykkvinwketlkfpeevelseeakdlierliadaekrlgkkGvdeikkhpf  293

         f++e+pqety+kv+nw++tl fp+ev++s+ a++li  l++d++krlg   v+ +k+h+f

Q: 318   FCSESPQETYRKVMNWRNTLVFPDEVPISDIARNLILSLCTDPDKRLGFPEVESLKEHAF  377

         ************************************************************

S: 294   f  294

Q: 378   F  378

Domain Sequence
(FASTA)

FEMLKVIGRG AFGEVRLVQK KDTGHIYAMK MLRKKDMMDK EQVAHVRAER DILVEAENPW 60

VVKMFYSFQD TYNLYLIMEF LPGGDMMTLL IFNSKTDTLT EEQTQFYMAE SVLAINSIHE 120

LGFIHRDIKP DNLLIDARGH VKLSDFGLCT GLKKAHSTDY YRDLTQAQPI DFTTRPLNAN 180

DSRRKAETWK SKRRKLAYST VGTPDYIAPE VFQQSGYNLS CDWWSLGVIM YESLIGYPPF 240

CSESPQETYR KVMNWRNTLV FPDEVPISDI ARNLILSLCT DPDKRLGFPE VESLKEHAFF 300

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013