EKS-CIS-00066

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CIS-00066

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	363.2	8.3E-109	20	315	296

Status

Unreviewed

Ensembl Protein

ENSCSAVP00000011226

UniProt Accession

H2Z0W4;

Protein Name

Protein Synonyms/Alias

Gene Name

Csa.2443

Gene Synonyms/Alias

Csa.2443;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCSAVG00000006568	ENSCSAVP00000011225	ENSCSAVT00000011356
ENSCSAVG00000006568	ENSCSAVP00000011226	ENSCSAVT00000011357

Organism

Ciona savignyi

Functional Description

Protein Length

374

Protein Sequence
(FASTA)

MAKGLDPNMD FPFCHDVGKY ERITKIGQGT FGEVFKARCR KTDRHVALKK VIMENEKEGF 60

PITALREIKI LQLLKHDNIV DLIEICRTKP TQYNRSKGSI YLVFEFCAHD LAGLLSNATV 120

KFTLGEIKKT MLQLLEGLFY IHRNKILHRD MKAANILITK NGVLKLADFG LARAFSYTKT 180

GQANRYTNRV VTLWYRPPEL LLGDRDYGPP IDLWGAGCIM TEMWTRSPIM QGHTEQRLTL 240

ISQLCGSIMP EVWPGVEKYE LFTKMELPKG QKRRVKERLK AYVRDQYALD LIDKLLTLDP 300

KHRIDSDDAL NHDFFWTEPL PCDLTNMLSQ HKTSMFEYLA PPRKPTTTAG HHHRHPNAGA 360

TKQQPTDPAY DRIF 374

Nucleotide Sequence
(FASTA)

ATGGCTAAGG GTTTGGACCC TAACATGGAC TTTCCATTTT GCCATGATGT TGGCAAGTAT 60

GAAAGAATCA CAAAAATTGG ACAAGGGACA TTCGGGGAGG TTTTCAAAGC ACGTTGTAGA 120

AAAACAGATC GTCATGTTGC TCTCAAGAAA GTGATCATGG AAAACGAAAA AGAGGGTTTC 180

CCGATCACAG CTTTGCGTGA AATAAAGATA CTACAACTTC TTAAACACGA TAATATTGTT 240

GATCTGATCG AAATCTGCCG CACAAAGCCA ACACAGTATA ATAGGTCCAA AGGCTCTATT 300

TATCTTGTTT TTGAGTTTTG TGCACACGAC TTAGCTGGGC TACTGAGCAA TGCTACAGTT 360

AAATTCACAT TGGGTGAAAT AAAAAAGACA ATGCTCCAAT TATTGGAAGG ACTATTCTAC 420

ATCCATCGAA ATAAAATATT GCACCGTGAC ATGAAAGCAG CAAACATATT AATCACAAAG 480

AATGGAGTTT TGAAATTAGC TGATTTTGGA TTGGCGAGAG CTTTTAGTTA CACGAAGACT 540

GGCCAAGCGA ATAGATATAC AAACAGAGTG GTCACATTAT GGTACCGACC GCCAGAACTA 600

CTGTTGGGTG ACCGGGACTA TGGACCCCCC ATTGATTTGT GGGGAGCTGG GTGTATTATG 660

ACAGAGATGT GGACCCGTAG TCCGATTATG CAGGGCCACA CTGAACAGAG GCTTACATTA 720

ATCAGTCAAC TATGCGGATC TATAATGCCC GAGGTTTGGC CTGGCGTCGA AAAATATGAA 780

CTCTTTACCA AAATGGAGCT ACCAAAGGGT CAAAAACGCA GAGTAAAAGA ACGGCTTAAA 840

GCGTATGTCC GCGACCAATA TGCACTGGAC TTGATTGACA AGCTGTTAAC CTTGGACCCG 900

AAGCATCGAA TTGATTCAGA TGACGCTTTA AATCACGACT TCTTTTGGAC TGAACCTCTG 960

CCCTGTGACC TCACAAACAT GCTTTCACAA CACAAAACGT CAATGTTCGA GTATTTGGCG 1020

CCGCCGAGAA AGCCAACAAC CACCGCAGGC CACCACCACA GACATCCAAA TGCAGGAGCT 1080

ACGAAACAAC AGCCCACTGA TCCAGCTTAT GATCGGATTT TTTAA 1125

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         ye+++kig+Gt+g+v+ka++++t++ vAlKk+ +e+ekeg+pitalrEi++l+ lkh+ni

Q: 20    YERITKIGQGTFGEVFKARCRKTDRHVALKKVIMENEKEGFPITALREIKILQLLKHDNI  79

         899*********************************************************

S: 61    vkLlevva.......kdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqllegl  113

         v+L+e++        ++k ++yLvfef+++dL+ ll++ +  k++l e+k+ +lqllegl

Q: 80    VDLIEICRtkptqynRSKGSIYLVFEFCAHDLAGLLSNATV-KFTLGEIKKTMLQLLEGL  138

         ************9988889*********************9.******************

S: 114   aylHsnkilHRDlKpqNlLiskegklklaDfGlarafssplk....tytkevvTlwYraP  169

          y+H+nkilHRD+K++N+Li+k+g+lklaDfGlarafs ++     +yt++vvTlwYr+P

Q: 139   FYIHRNKILHRDMKAANILITKNGVLKLADFGLARAFSYTKTgqanRYTNRVVTLWYRPP  198

         *************************************6555444447*************

S: 170   elLlgakeYstavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevs  229

         elLlg+++Y+  +D+W++gci++e++tr+p++qg++e ++l+ i++l+g++  +vwp+v+

Q: 199   ELLLGDRDYGPPIDLWGAGCIMTEMWTRSPIMQGHTE-QRLTLISQLCGSIMPEVWPGVE  257

         ***********************************98.58********************

S: 230   klpeyk.ksfpkkkkkklkekvkklk.ek.aldllekllaldpkkRisakealqhkyf  284

         k++ ++ +++pk +k+++ke++k++  ++ aldl++kll+ldpk+Ri++++al+h++f

Q: 258   KYELFTkMELPKGQKRRVKERLKAYVrDQyALDLIDKLLTLDPKHRIDSDDALNHDFF  315

         *****9899***9999******887634469*************************98

Domain Sequence
(FASTA)

YERITKIGQG TFGEVFKARC RKTDRHVALK KVIMENEKEG FPITALREIK ILQLLKHDNI 60

VDLIEICRTK PTQYNRSKGS IYLVFEFCAH DLAGLLSNAT VKFTLGEIKK TMLQLLEGLF 120

YIHRNKILHR DMKAANILIT KNGVLKLADF GLARAFSYTK TGQANRYTNR VVTLWYRPPE 180

LLLGDRDYGP PIDLWGAGCI MTEMWTRSPI MQGHTEQRLT LISQLCGSIM PEVWPGVEKY 240

ELFTKMELPK GQKRRVKERL KAYVRDQYAL DLIDKLLTLD PKHRIDSDDA LNHDFF 296

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013