EKS-CIS-00243

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CIS-00243

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/RIPK	187.0	4.2E-55	26	308	283

Status

Unreviewed

Ensembl Protein

ENSCSAVP00000011718

UniProt Accession

H2Z2A6;

Protein Name

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCSAVG00000006870	ENSCSAVP00000011718	ENSCSAVT00000011855

Organism

Ciona savignyi

Functional Description

Protein Length

313

Protein Sequence
(FASTA)

MNEQGGKNRN SFDFSPIPII KDSELSKVRL IGSGGYGQVL LCNFSKNGNG TSRKVVLKQL 60

LKGAIPSRDL KYLQNEAKIL WGLNSPFVIS LEGLNCSESQ FSIVMQFAEY GSCTDFFGTG 120

ERKEFNEWQM EELWPLKSRI AFQVIQGMIY LHGIKPKRIL HLDLKSQNVL LDNNLNVKLC 180

DFGLSQMNTL SLLTKSLTCT YGVVTGKNDG RIRGTVSHIA PEHFKYVNAK PSVKSDAYSF 240

GIFLWELMTN EQPYRHALQD AVILAVRDNG ERPDDDLLPP SAPIFMVSIM AQCFQEKPID 300

RPDFKDMRSL FVD 313

Nucleotide Sequence
(FASTA)

ATGAATGAAC AAGGTGGGAA AAATAGGAAT TCATTTGACT TCAGTCCCAT ACCAATTATA 60

AAAGATAGCG AACTGTCAAA AGTAAGATTG ATTGGTTCTG GAGGATACGG TCAAGTGTTG 120

CTGTGCAATT TCAGTAAGAA TGGAAATGGG ACTTCTAGAA AAGTCGTGTT AAAACAACTA 180

CTCAAAGGCG CCATACCAAG CCGAGATTTA AAGTATTTAC AAAATGAAGC TAAAATTTTA 240

TGGGGACTGA ACTCGCCGTT TGTTATATCG CTGGAAGGAT TGAACTGCAG TGAAAGTCAA 300

TTTTCCATCG TGATGCAATT CGCTGAATAT GGTTCTTGCA CTGACTTTTT CGGTACCGGA 360

GAGCGAAAGG AGTTTAATGA GTGGCAAATG GAAGAGCTTT GGCCACTGAA ATCAAGAATC 420

GCTTTTCAGG TAATACAGGG TATGATCTAT TTACATGGAA TTAAACCAAA GAGAATACTT 480

CATCTTGATC TCAAATCACA AAACGTACTA TTGGACAATA ATTTGAATGT GAAGCTTTGC 540

GATTTTGGTC TCTCACAAAT GAACACCTTA TCCTTGCTGA CAAAGTCGCT TACCTGTACA 600

TACGGAGTAG TAACGGGTAA AAATGATGGG CGTATTCGAG GAACTGTTAG CCACATTGCA 660

CCGGAGCATT TTAAATACGT CAATGCTAAA CCATCGGTTA AATCAGATGC ATACAGCTTT 720

GGTATTTTCT TGTGGGAACT GATGACCAAC GAACAACCTT ACAGACATGC TCTTCAAGAT 780

GCAGTAATTT TGGCGGTGCG AGATAATGGA GAAAGACCAG ACGATGACCT GCTTCCACCT 840

TCGGCTCCAA TATTTATGGT TTCTATTATG GCGCAATGTT TTCAAGAAAA ACCAATTGAC 900

CGACCTGATT TTAAAGATAT GAGAAGTTTG TTCGTTGAC 939

Domain Profile

S: 2     eelelvgsGgfgkvfkarhrkwrvevavk...slvlktdaldserkelleeakkmeklrf  58

         ++++l+gsGg+g+v  ++  k +     k   +  lk+   +++ k+l +eak++  l+

Q: 26    SKVRLIGSGGYGQVLLCNFSKNGNGTSRKvvlKQLLKGAIPSRDLKYLQNEAKILWGLNS  85

         68899*************998765444332223788999999******************

S: 59    syvlkllGvikeeeklglvmeymenGsLeklLks.........eielpwplkfRilkevv  109

          +v++l+G+   e + ++vm++ e Gs ++   +         ++e  wplk Ri   v+

Q: 86    PFVISLEGLNCSESQFSIVMQFAEYGSCTDFFGTgerkefnewQMEELWPLKSRIAFQVI  145

         *********8888899******99999987775422222222256666************

S: 110   lgmnyLhslkPp.llhkDLkpeniLlDnelhvkiaDfGlskf.m........eessqske  159

          gm yLh +kP  +lh+DLk++n+LlDn+l vk+ DfGls++ +        +

Q: 146   QGMIYLHGIKPKrILHLDLKSQNVLLDNNLNVKLCDFGLSQMnTlslltkslT--CTYGV  203

         ***********659***************************953555542211..11122

S: 160   vsssa.....egGtlaYlaPelleevnkkaseksDvYsfaiviWavlakkepyeeeknsl  214

         v   +      +Gt++++aPe+++ vn+k+s ksD Ysf+i +W+++++ +py ++ +

Q: 204   VT--GkndgrIRGTVSHIAPEHFKYVNAKPSVKSDAYSFGIFLWELMTNEQPYRHALQDA  261

         22..13355789************************************************

S: 215   qiiivvkkgnRPeleevseelPrevpqlieLmkrcWeadpeeRPsFleie  264

         +i++v ++g+RP+ + ++ + P     ++++m +c++++p +RP F++++

Q: 262   VILAVRDNGERPDDDLLPPSAPIF---MVSIMAQCFQEKPIDRPDFKDMR  308

         *************99999999955...*******************9986

Domain Sequence
(FASTA)

SKVRLIGSGG YGQVLLCNFS KNGNGTSRKV VLKQLLKGAI PSRDLKYLQN EAKILWGLNS 60

PFVISLEGLN CSESQFSIVM QFAEYGSCTD FFGTGERKEF NEWQMEELWP LKSRIAFQVI 120

QGMIYLHGIK PKRILHLDLK SQNVLLDNNL NVKLCDFGLS QMNTLSLLTK SLTCTYGVVT 180

GKNDGRIRGT VSHIAPEHFK YVNAKPSVKS DAYSFGIFLW ELMTNEQPYR HALQDAVILA 240

VRDNGERPDD DLLPPSAPIF MVSIMAQCFQ EKPIDRPDFK DMR 283

Keyword

Complete proteome; Kinase; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF07714

; Pkinase_Tyr; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013