EKS-CIS-00082

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CIS-00082

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	334.9	3.2E-100	23	274	252

Status

Unreviewed

Ensembl Protein

ENSCSAVP00000012004

UniProt Accession

H2Z342;

Protein Name

Protein Synonyms/Alias

Gene Name

Csa.8767

Gene Synonyms/Alias

Csa.8767;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCSAVG00000007055	ENSCSAVP00000012004	ENSCSAVT00000012143

Organism

Ciona savignyi

Functional Description

Protein Length

491

Protein Sequence
(FASTA)

MDDTKPLKKL SEESLTKQPD EVFDLLEKLG EGAYGCVFKA IYKEAGQVVA IKQVPVESDL 60

QEIIKEIAIM QQCDSLYVVK YYGSYFKNTD LWIVMEYCGA GSVSDIIRLR RKTLTEDEIA 120

TILKDTLKGL EYLHFMRKIH RDVKAGNILL NTVGNSKLAD FGVAGQLTDT MAKRNTVIGT 180

PFWMAPEVIQ EIGYDCVADI WSLGITAIEM AEGKPPYSDI HPMRAIFMIP TKPPPTFRDP 240

EKWSETFINF VSQCLVKSPA QRATATTLLQ HDFIKNAKPH SNLREMVQEA MEIKRRKLKN 300

GSDSDSDDED DGDEEADVGT MVKVSVDSVD GSGTVRVANS LASSITGSAT MIQHDTDMGL 360

GTMVINDDDD EDTGTMQRRD VDTVVKNSDS DRPAFMNYFD NVGSGSGNSG AAASAGSKGL 420

PPEEAWKFSK NISEMDFSFL KNLSVNDLQM RLNALDPLME KEIEDLRKRY FEKRQPILDA 480

IDAKKKRQQN F 491

Nucleotide Sequence
(FASTA)

ATGGATGATA CTAAACCTCT TAAAAAGTTA AGTGAAGAAA GTTTGACCAA ACAACCTGAT 60

GAAGTATTCG ATTTACTGGA GAAATTAGGA GAGGGTGCTT ATGGATGCGT GTTCAAAGCA 120

ATATATAAAG AGGCCGGGCA GGTTGTGGCC ATTAAACAAG TCCCTGTCGA ATCGGACCTA 180

CAAGAAATTA TAAAAGAAAT TGCAATTATG CAACAGTGTG ATTCCCTCTA TGTTGTAAAG 240

TACTATGGAA GTTACTTTAA AAATACAGAC CTATGGATTG TCATGGAATA TTGTGGAGCT 300

GGTTCCGTGT CTGACATCAT CAGATTGCGT AGAAAGACTC TGACAGAAGA TGAAATTGCT 360

ACAATTTTAA AAGACACATT AAAGGGACTA GAGTACCTTC ATTTTATGAG GAAAATTCAC 420

AGAGATGTCA AAGCTGGGAA TATTCTGTTA AACACAGTTG GAAACAGCAA ACTGGCAGAT 480

TTTGGAGTTG CTGGACAATT GACTGACACA ATGGCCAAGC GAAACACAGT TATAGGAACA 540

CCATTTTGGA TGGCTCCTGA AGTTATTCAA GAAATCGGAT ACGACTGTGT GGCAGACATT 600

TGGTCACTGG GCATCACAGC AATTGAAATG GCAGAAGGGA AACCCCCTTA TTCAGACATT 660

CATCCCATGA GAGCCATATT TATGATCCCT ACGAAACCAC CTCCAACTTT TAGAGATCCA 720

GAAAAGTGGT CCGAAACTTT CATTAACTTC GTGAGTCAGT GTTTAGTAAA GAGCCCTGCC 780

CAAAGAGCAA CTGCTACCAC TCTGTTGCAG CATGATTTCA TTAAAAATGC CAAACCACAC 840

AGCAATCTGA GGGAAATGGT GCAAGAAGCA ATGGAGATCA AACGACGGAA GTTGAAGAAC 900

GGATCCGACT CCGATTCGGA TGATGAGGAT GATGGAGATG AAGAAGCGGA TGTGGGGACC 960

ATGGTGAAAG TATCCGTGGA TAGTGTGGAT GGTTCTGGTA CTGTAAGGGT TGCCAACTCT 1020

TTGGCTTCTT CTATTACAGG AAGTGCTACC ATGATACAAC ACGATACCGA CATGGGACTT 1080

GGCACGATGG TCATCAACGA TGATGATGAT GAAGACACCG GAACCATGCA GAGGAGAGAT 1140

GTGGACACTG TGGTGAAGAA TAGCGACAGT GATAGACCTG CTTTCATGAA CTATTTCGAC 1200

AATGTAGGCT CAGGCAGCGG CAATTCTGGA GCCGCTGCTT CTGCAGGATC AAAAGGTCTC 1260

CCACCAGAGG AAGCATGGAA ATTCAGCAAA AATATCTCCG AAATGGACTT CAGCTTCTTA 1320

AAAAATCTTT CAGTTAATGA CCTGCAAATG CGCCTCAATG CTTTGGACCC ATTAATGGAG 1380

AAAGAAATAG AGGACTTGAG AAAAAGATAC TTTGAGAAAC GGCAGCCGAT TTTGGATGCG 1440

ATTGATGCTA AGAAAAAGAG GCAGCAAAAT TTT 1473

Domain Profile

S: 1     yelleeigkGalgkvylarekktgelvaikkinlekqekleelqkeisvlkklkhpnive  60

         ++lle++g+Ga+g v++a  k+ g++vaik++ +e+  +l+e++kei +++++++ ++v+

Q: 23    FDLLEKLGEGAYGCVFKAIYKEAGQVVAIKQVPVES--DLQEIIKEIAIMQQCDSLYVVK  80

         899********************************7..9*********************

S: 61    ylesflkeeelwlvmeylagGslsdlvkeelkselkEeqiayilrevlkaLeylHskkvi  120

         y++s++k+++lw+vmey+ +Gs+sd+++  ++++l+E++ia+il+++lk+LeylH +++i

Q: 81    YYGSYFKNTDLWIVMEYCGAGSVSDIIR-LRRKTLTEDEIATILKDTLKGLEYLHFMRKI  139

         ****************************.999****************************

S: 121   HrdikakniLlteegeVkLsdfgvaaqlektrkkrktvvgtpywmAPEviaqeekgYdek  180

         Hrd+ka+niLl++ g+ kL+dfgva ql++t++kr+tv+gtp+wmAPEvi+  e gYd+

Q: 140   HRDVKAGNILLNTVGNSKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQ--EIGYDCV  197

         ***************************************************..9******

S: 181   aDiwslGItaielaegepPfkdleplkallkilkneppklkskkkfskefkefvekclqk  240

         aDiwslGItaie+aeg+pP++d++p++a+++i++++pp++++++k+s++f +fv++cl k

Q: 198   ADIWSLGITAIEMAEGKPPYSDIHPMRAIFMIPTKPPPTFRDPEKWSETFINFVSQCLVK  257

         ************************************************************

S: 241   npekRpsasellkhkFl  257

         +p++R++a++ll+h F+

Q: 258   SPAQRATATTLLQHDFI  274

         ****************7

Domain Sequence
(FASTA)

FDLLEKLGEG AYGCVFKAIY KEAGQVVAIK QVPVESDLQE IIKEIAIMQQ CDSLYVVKYY 60

GSYFKNTDLW IVMEYCGAGS VSDIIRLRRK TLTEDEIATI LKDTLKGLEY LHFMRKIHRD 120

VKAGNILLNT VGNSKLADFG VAGQLTDTMA KRNTVIGTPF WMAPEVIQEI GYDCVADIWS 180

LGITAIEMAE GKPPYSDIHP MRAIFMIPTK PPPTFRDPEK WSETFINFVS QCLVKSPAQR 240

ATATTLLQHD FI 252

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007165	; P:signal transduction

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR011524	; SARAH.
IPR024205	; SARAH_domain.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF11629	; Mst1_SARAH; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS50951	; SARAH; 1.

Prints

Created Date

20-Feb-2013