EKS-CIS-00224

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CIS-00224

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/MAPK	334.7	4.0E-100	6	301	296

Status

Unreviewed

Ensembl Protein

ENSCSAVP00000012407

UniProt Accession

H2Z495;

Protein Name

Protein Synonyms/Alias

Gene Name

Csa.3781

Gene Synonyms/Alias

Csa.3781;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCSAVG00000007295	ENSCSAVP00000012407	ENSCSAVT00000012551

Organism

Ciona savignyi

Functional Description

Protein Length

402

Protein Sequence
(FASTA)

IMEIEADKPI GYGAFGVVWA VKDPRDGKQV ALKKMPNVFH NIMSAKRVLR ELKMLCYFNH 60

ENVLSAVDVL PPVDSPYEEM YVITQLMHTD LHKIIVSQQA LTTDHIRLFL YQILRGVKYL 120

HGARILHRDI KPGNLLINSD CRLKICDFGL ARLEEPDESK YMTQEVVTQY YRAPELLLGA 180

RHYGNAVDIW SIGCIFAELL SRRILFQANS PVTQIDMIYN LLVDSNVAPS QQFSHRSNST 240

LDMEARAQLY QSVSRLPAAP STFYHLAPNM THEAAHLISR LLVWDPSKRV SCTEALRHIY 300

LREGRLRYHT SLCRCCCITA EGIRHAADHE FEAMPDMVFD DSYEDDLRTV DDVRNAVTDF 360

INSQPCGRKA PLRINPNSAV FPRFVASTVA HSHPVPTSSK MA 402

Nucleotide Sequence
(FASTA)

ATAATGGAAA TCGAAGCTGA CAAGCCGATA GGCTATGGTG CATTTGGAGT AGTTTGGGCA 60

GTAAAAGACC CAAGGGATGG GAAACAAGTC GCATTAAAGA AGATGCCAAA TGTATTCCAC 120

AACATTATGT CTGCCAAGCG GGTGCTAAGG GAATTGAAGA TGCTTTGCTA CTTTAACCAT 180

GAAAACGTTT TATCAGCGGT TGATGTGTTG CCACCGGTCG ACAGCCCGTA TGAAGAAATG 240

TATGTGATCA CCCAATTAAT GCACACTGAC CTGCATAAGA TCATTGTCTC CCAACAAGCA 300

CTCACAACAG ACCACATTCG GCTATTTCTG TACCAGATAT TGAGAGGTGT GAAATACCTG 360

CATGGCGCAA GAATACTCCA TCGCGACATC AAACCAGGCA ACCTACTGAT AAACAGCGAC 420

TGTCGTTTGA AGATCTGCGA TTTCGGTCTC GCTCGATTGG AAGAACCAGA CGAATCGAAG 480

TACATGACGC AAGAAGTCGT CACTCAGTAT TACAGGGCTC CGGAATTATT ACTGGGAGCA 540

CGGCATTACG GGAACGCCGT TGATATTTGG AGCATTGGAT GCATCTTTGC TGAGTTGTTG 600

TCAAGAAGAA TCCTGTTTCA AGCCAACAGT CCAGTCACCC AGATCGACAT GATATACAAC 660

CTGTTGGTGG ATTCGAACGT GGCGCCATCT CAGCAATTCT CCCACCGATC CAACTCGACT 720

TTGGACATGG AGGCACGAGC TCAACTCTAC CAGTCAGTTT CCCGTCTCCC CGCTGCCCCG 780

AGCACGTTCT ACCACCTCGC ACCGAATATG ACCCATGAAG CTGCTCATCT TATATCAAGA 840

CTTTTGGTTT GGGACCCGAG CAAACGCGTG TCTTGCACGG AAGCTCTCCG ACACATATAT 900

TTGCGCGAGG GCAGGCTACG CTACCACACC AGTTTATGCC GTTGCTGCTG CATAACCGCC 960

GAAGGAATCC GACACGCGGC CGACCACGAG TTTGAAGCTA TGCCCGATAT GGTGTTCGAC 1020

GACTCCTACG AGGACGACCT CAGGACGGTT GATGACGTCA GAAACGCCGT AACGGATTTT 1080

ATCAACAGTC AACCATGTGG TCGGAAAGCG CCGCTACGTA TCAACCCAAA CAGCGCCGTT 1140

TTCCCCCGTT TTGTAGCCTC CACCGTCGCC CATTCCCACC CCGTGCCTAC CTCCTCGAAA 1200

ATGGCTTAA 1209

Domain Profile

S: 3     slkplgeGaygvvvsavdkrteervaikklsrpfqketsakrtlRElkllkelkheNiik  62

         + kp+g Ga+gvv++++d r++++va+kk+ ++f++ +sakr+lRElk+l  ++heN+++

Q: 6     ADKPIGYGAFGVVWAVKDPRDGKQVALKKMPNVFHNIMSAKRVLRELKMLCYFNHENVLS  65

         6799********************************************************

S: 63    lldvftpeeeleelkdvYlvtelmetdLkkviksq.klsdehiklllyqilrglkylHsa  121

          +dv+ p +  + ++++Y++t+lm+tdL+k+i sq  l+ +hi+l+lyqilrg+kylH a

Q: 66    AVDVLPPVD--SPYEEMYVITQLMHTDLHKIIVSQqALTTDHIRLFLYQILRGVKYLHGA  123

         *******99..99******************999989***********************

S: 122   nviHrDlKPsNllvnedcelkildFGlarsadkekekklteyvatrwYraPeillslkey  181

         +++HrD+KP+Nll+n+dc+lki+dFGlar ++++++k +t++v+t++YraPe+ll +++y

Q: 124   RILHRDIKPGNLLINSDCRLKICDFGLARLEEPDESKYMTQEVVTQYYRAPELLLGARHY  183

         **********************************9999**********************

S: 182   tkavDiWsvGCIlaElltgkplfpgkdeidqlekilevlgt....pseeflkk....ies  233

          +avDiWs+GCI+aEll++++lf++++ + q+++i+++l      ps++f ++    +

Q: 184   GNAVDIWSIGCIFAELLSRRILFQANSPVTQIDMIYNLLVDsnvaPSQQFSHRsnstLDM  243

         ***********************************9998641222566665441111344

S: 234   eearnyikslp..kkkkkdfeelfpkaseealdLleklLvldpdkRisveeaLehpYl  289

         e  +++ +s++  + +  +f +l p+ ++ea +L+++lLv+dp+kR+s +eaL+h Yl

Q: 244   EARAQLYQSVSrlPAAPSTFYHLAPNMTHEAAHLISRLLVWDPSKRVSCTEALRHIYL  301

         444555565552234455999**********************************997

Domain Sequence
(FASTA)

ADKPIGYGAF GVVWAVKDPR DGKQVALKKM PNVFHNIMSA KRVLRELKML CYFNHENVLS 60

AVDVLPPVDS PYEEMYVITQ LMHTDLHKII VSQQALTTDH IRLFLYQILR GVKYLHGARI 120

LHRDIKPGNL LINSDCRLKI CDFGLARLEE PDESKYMTQE VVTQYYRAPE LLLGARHYGN 180

AVDIWSIGCI FAELLSRRIL FQANSPVTQI DMIYNLLVDS NVAPSQQFSH RSNSTLDMEA 240

RAQLYQSVSR LPAAPSTFYH LAPNMTHEAA HLISRLLVWD PSKRVSCTEA LRHIYL 296

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004707	; F:MAP kinase activity
GO:0000165	; P:MAPK cascade

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR003527	; MAP_kinase_CS.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS01351	; MAPK; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013