EKS-CIS-00206

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CIS-00206

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/PKC	429.3	5.6E-129	159	427	269

Status

Unreviewed

Ensembl Protein

ENSCSAVP00000012991

UniProt Accession

H2Z5X8;

Protein Name

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCSAVG00000007632	ENSCSAVP00000012991	ENSCSAVT00000013140
ENSCSAVG00000007632	ENSCSAVP00000012990	ENSCSAVT00000013139

Organism

Ciona savignyi

Functional Description

Protein Length

501

Protein Sequence
(FASTA)

SFQLELAEAL RLYKMNSEPV LLLHIFAGIP MEPGLLCPGE HKLYRHGARR WYKLKRMFHL 60

GICPKNKQDF HLVICPISYT RFPFGNLAYK LYKIFIWESL HKIILHYSPP PFSPLYTTKM 120

QYTSRPHPYS CTRYSNNTSL QSNPEEASNT ASGFGLKDFD LLKVIGRGSY AKVLLVRLKV 180

TDKMYAMKVI KKELVTDEED IDWVQTEKHV FETASNYPFL VGLHSCFQTP ERLFFVIEYV 240

NGGDLMFHMQ RQRKLPEEHA RFYAAEIVLA LHFLHEKGII YRDLKLDNVL LDTDGHVKLT 300

DYGMCKEGVR KGNTTATFCG TPNYIAPEIL RGEDYDFSVD WWALGVLMFE MMAGRSPFDI 360

VGMADNPEQN TEDYLFQVIL EKVIRIPRSL SVKASSVLKG FLNKIPVDRL GCNHESGFQD 420

ILDHIFFRTI DWDLLHAKQV VPPFRPNIED DLGLDNFDKQ FTQEPVQLTP TETTVVGKID 480

QSDFEGFEYI NPLLMSTEDA V 501

Nucleotide Sequence
(FASTA)

TCATTTCAGC TGGAGTTAGC TGAAGCATTG CGCTTGTACA AAATGAACAG CGAACCCGTT 60

TTACTTTTGC ACATTTTTGC CGGAATACCA ATGGAGCCAG GGTTACTATG TCCAGGAGAA 120

CACAAACTAT ACAGACACGG TGCGAGGAGG TGGTACAAGT TAAAGAGGAT GTTTCATTTG 180

GGCATCTGTC CTAAAAATAA ACAAGATTTT CATTTGGTTA TCTGTCCTAT AAGTTATACA 240

AGGTTTCCAT TTGGGAATCT GGCCTATAAG TTATACAAGA TTTTCATTTG GGAATCTCTC 300

CATAAAATTA TACTTCATTA CAGTCCACCA CCCTTTTCCC CCTTATATAC TACTAAAATG 360

CAGTACACCT CAAGACCTCA CCCTTATTCT TGCACCAGAT ACTCAAATAA TACTTCATTA 420

CAGTCCAACC CTGAAGAAGC AAGTAATACA GCCTCAGGAT TTGGATTAAA AGATTTTGAT 480

CTTCTAAAAG TAATTGGCCG TGGAAGTTAT GCTAAAGTGC TACTTGTCCG ATTAAAAGTG 540

ACCGACAAAA TGTATGCAAT GAAGGTCATA AAGAAGGAGT TAGTCACAGA TGAAGAAGAT 600

ATTGACTGGG TGCAGACTGA GAAACATGTA TTCGAAACCG CCTCAAATTA CCCCTTTCTA 660

GTCGGACTAC ATTCTTGTTT TCAGACCCCC GAGCGATTGT TCTTCGTCAT CGAGTATGTG 720

AACGGAGGTG ATCTCATGTT CCACATGCAG CGGCAACGGA AGTTACCGGA AGAACATGCC 780

AGGTTCTACG CAGCAGAAAT AGTGCTGGCG CTACACTTCC TACATGAAAA GGGAATTATT 840

TACCGCGATT TGAAACTCGA CAACGTTTTG TTGGATACAG ATGGTCATGT CAAGCTTACT 900

GATTATGGAA TGTGCAAGGA GGGTGTAAGG AAAGGCAACA CCACGGCTAC TTTCTGCGGA 960

ACCCCCAACT ACATCGCCCC CGAGATACTG CGGGGTGAAG ATTACGACTT CTCCGTCGAT 1020

TGGTGGGCAC TAGGTGTCCT CATGTTTGAG ATGATGGCGG GTAGAAGTCC GTTCGATATC 1080

GTTGGGATGG CTGACAATCC TGAACAGAAC ACAGAGGATT ATCTCTTCCA GGTTATCCTT 1140

GAAAAAGTGA TCAGAATACC CCGTTCTCTG TCAGTCAAGG CTTCGTCGGT TTTGAAAGGA 1200

TTTCTAAACA AGATCCCAGT GGACAGACTG GGTTGCAACC ACGAGAGTGG TTTCCAGGAT 1260

ATTTTGGATC ACATCTTCTT TCGAACTATA GATTGGGATT TGCTTCACGC CAAGCAGGTG 1320

GTTCCCCCAT TTAGACCCAA CATCGAAGAC GACCTGGGTC TCGATAATTT CGACAAGCAG 1380

TTCACTCAGG AACCTGTCCA ACTGACCCCA ACAGAGACCA CAGTAGTCGG GAAAATTGAT 1440

CAATCAGATT TCGAAGGGTT CGAGTACATA AACCCACTTC TGATGTCGAC TGAAGACGCA 1500

GTTTAA 1506

Domain Profile

S: 1     fellkvlGkGsfgkvllaelkktdelyaikvlkkdvvlqdddveltlvekrvlalaskkp  60

         f+llkv+G+Gs++kvll++lk td++ya+kv+kk++v++++d++++++ek+v+++as+ p

Q: 159   FDLLKVIGRGSYAKVLLVRLKVTDKMYAMKVIKKELVTDEEDIDWVQTEKHVFETASNYP  218

         89**********************************************************

S: 61    flvqlfscfqtedrlffvleyvnGGdlmfhiqkarklkeerarfyaaeiilalkflhekg  120

         flv l+scfqt +rlffv+eyvnGGdlmfh+q++rkl+ee+arfyaaei+lal+flhekg

Q: 219   FLVGLHSCFQTPERLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEIVLALHFLHEKG  278

         ************************************************************

S: 121   iiyrdlkldnvlldaeGhikladfGlckeeilegkttstfcGtPdyiaPeilkeeeygks  180

         iiyrdlkldnvlld++Gh+kl+d+G+cke++ +g+tt+tfcGtP+yiaPeil++e+y++s

Q: 279   IIYRDLKLDNVLLDTDGHVKLTDYGMCKEGVRKGNTTATFCGTPNYIAPEILRGEDYDFS  338

         ************************************************************

S: 181   vdwwalGvllyemlagqsPfe.........gededelfesilekevlyPkslskeaveil  231

         vdwwalGvl++em+ag+sPf+         +++ed+lf++ilek +++P+sls++a+++l

Q: 339   VDWWALGVLMFEMMAGRSPFDivgmadnpeQNTEDYLFQVILEKVIRIPRSLSVKASSVL  398

         *****************************99*****************************

S: 232   kglltkdpekrlGvk.eegeedikehaff  259

         kg+l+k p +rlG++ e+g +di +h ff

Q: 399   KGFLNKIPVDRLGCNhESGFQDILDHIFF  427

         **************6699**********9

Domain Sequence
(FASTA)

FDLLKVIGRG SYAKVLLVRL KVTDKMYAMK VIKKELVTDE EDIDWVQTEK HVFETASNYP 60

FLVGLHSCFQ TPERLFFVIE YVNGGDLMFH MQRQRKLPEE HARFYAAEIV LALHFLHEKG 120

IIYRDLKLDN VLLDTDGHVK LTDYGMCKEG VRKGNTTATF CGTPNYIAPE ILRGEDYDFS 180

VDWWALGVLM FEMMAGRSPF DIVGMADNPE QNTEDYLFQV ILEKVIRIPR SLSVKASSVL 240

KGFLNKIPVD RLGCNHESGF QDILDHIFF 269

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR000270	; OPR_PB1.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00564	; PB1; 1.
PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00666	; PB1; 1.
SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013