EKS-CIS-00092

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CIS-00092

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/PEK	272.7	3.4E-81	105	522	418

Status

Unreviewed

Ensembl Protein

ENSCSAVP00000013204

UniProt Accession

H2Z6J2;

Protein Name

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCSAVG00000007753	ENSCSAVP00000013204	ENSCSAVT00000013353

Organism

Ciona savignyi

Functional Description

Protein Length

562

Protein Sequence
(FASTA)

IPQEVLLGSL LEHICQLYEA DSKKAKQLFH IICKKLQKMK VMSPIAYLDE YASVRIQYKT 60

SFYNLIHSSL FTVQATGQLM EYGNLKVNRK DVFDFGVSRY KEEYDEIEVI GYGAFGKVYK 120

AINKIDGQVY AVKQIKCKSN GSEIMPETNK MLREVQSLAS MQHENIIRYH CAWIEHTPVS 180

EIEQTVPLRV SINTTPYSTN DTGSFGDYDP VEHEDGKFWQ PSSDSSDEDS SCSEEKSSSN 240

TGSLTTDVIF THGVMKRSTI RRVQSYIITG VSNAHLSSLS HIESNTRSHS VSSMQDIAIL 300

KRPEESQDEA PCYKPSIHVV MYIQMQLCNT TLKKWLVQRN QILTTKPDLS HVPASFCIFK 360

QIIAALNYIH KKGMLHRDIK PQNIFINDED QEPQIKLGDF GLARAKLSTS SSEPLTPIHE 420

MPVDFLSDEH TSGVGTSLYA SPEQLKGETY DDKADIYSAG IVLYELICPL GTTHERTVAI 480

NILRKQEIPT DFQRNAPSAV GLLKSILSHE YQTRPSAEQL LLSLDAIPEA TVDLKKQNEL 540

LRLENTKLKK MVKLYENELV KN 562

Nucleotide Sequence
(FASTA)

ATTCCACAAG AGGTTTTGCT AGGATCGTTG CTTGAACATA TCTGTCAGCT ATATGAAGCA 60

GACAGCAAGA AAGCGAAACA GCTTTTTCAC ATAATTTGCA AGAAGTTGCA GAAGATGAAA 120

GTAATGTCAC CCATTGCATA CCTGGATGAG TATGCTTCTG TGAGGATTCA GTACAAAACT 180

TCGTTTTATA ACTTAATTCA TTCGTCTCTA TTCACTGTAC AGGCTACTGG GCAGTTAATG 240

GAATACGGCA ACTTGAAAGT AAATAGAAAG GATGTCTTCG ATTTTGGGGT TTCAAGGTAC 300

AAGGAAGAGT ATGATGAAAT TGAAGTCATC GGTTATGGGG CATTTGGCAA AGTTTATAAA 360

GCGATAAATA AAATTGACGG ACAGGTATAT GCAGTGAAAC AAATCAAATG TAAAAGCAAT 420

GGATCGGAAA TCATGCCGGA GACGAATAAA ATGTTAAGAG AAGTCCAATC ATTAGCTTCC 480

ATGCAGCATG AGAATATAAT TCGTTATCAC TGTGCTTGGA TTGAACACAC TCCTGTCTCT 540

GAAATCGAAC AAACAGTCCC GTTAAGGGTG TCAATAAACA CAACACCGTA TAGCACGAAT 600

GATACCGGGT CTTTTGGGGA CTATGATCCA GTAGAGCACG AAGACGGAAA GTTCTGGCAG 660

CCCTCTAGTG ACTCTTCCGA CGAGGATTCT TCTTGCAGTG AGGAGAAAAG TTCAAGCAAT 720

ACTGGGTCTC TTACTACGGA CGTTATTTTT ACTCATGGGG TGATGAAAAG GTCGACAATC 780

CGGCGAGTGC AAAGTTATAT CATTACCGGG GTGTCAAATG CACATTTATC CAGCTTAAGT 840

CATATTGAGT CCAACACAAG ATCCCATTCA GTCAGCAGTA TGCAGGATAT CGCTATTTTA 900

AAGAGACCAG AGGAGAGTCA AGATGAGGCC CCTTGTTACA AACCTTCCAT ACATGTAGTA 960

ATGTACATAC AGATGCAACT ATGCAATACC ACGTTAAAGA AGTGGTTAGT GCAACGTAAT 1020

CAAATCCTGA CGACTAAACC TGATTTAAGC CATGTTCCTG CCTCCTTTTG CATTTTTAAA 1080

CAAATTATTG CAGCGTTGAA CTACATACAC AAGAAAGGTA TGCTCCATCG TGACATTAAA 1140

CCTCAAAATA TATTTATTAA CGATGAAGAC CAAGAACCAC AGATCAAGCT AGGAGATTTT 1200

GGACTTGCAA GGGCCAAGTT AAGCACTTCC AGTTCAGAGC CATTAACTCC AATCCACGAG 1260

ATGCCTGTAG ATTTCCTATC AGATGAGCAT ACTTCAGGAG TGGGTACTTC ACTGTATGCC 1320

TCTCCCGAGC AGTTGAAGGG GGAGACATAT GATGATAAAG CAGATATATA CAGTGCGGGG 1380

ATAGTCTTGT ACGAACTTAT TTGTCCACTG GGCACAACCC ATGAGCGCAC TGTGGCGATA 1440

AACATACTCC GAAAACAAGA AATTCCGACT GATTTTCAGC GTAATGCACC GTCTGCTGTT 1500

GGATTGCTCA AGTCAATTTT ATCTCACGAA TATCAAACCC GACCGTCTGC TGAACAGTTG 1560

TTACTGAGTT TGGACGCCAT TCCCGAAGCA ACCGTTGACC TTAAAAAGCA GAACGAACTA 1620

TTGCGATTGG AAAATACTAA ACTCAAAAAA ATGGTTAAAC TGTACGAGAA TGAATTGGTA 1680

AAAAAT 1686

Domain Profile

S: 2     eeikvlGkGgfgvVlkaknkldkkeyaikriklnkakke.l...ekverevkaLaklehp  57

         +ei+v+G G+fg+V+ka nk+d++ ya+k+ik++++ +e +   +k++rev++La+++h+

Q: 105   DEIEVIGYGAFGKVYKAINKIDGQVYAVKQIKCKSNGSEiMpetNKMLREVQSLASMQHE  164

         789**************************99999988764333379**************

S: 58    nivrYfaawleekeesl.........................................td  76

         ni+rY++aw+e+ + s                                          +d

Q: 165   NIIRYHCAWIEHTPVSEieqtvplrvsinttpystndtgsfgdydpvehedgkfwqpsSD  224

         **************9999********************************9999988544

S: 77    sseveaeaeleesesseesdtk......................................  98

         ss+++++ + e+s+s++ s t+

Q: 225   SSDEDSSCSEEKSSSNTGSLTTdvifthgvmkrstirrvqsyiitgvsnahlsslshies  284

         777777776666666665555579999999999999999999999999999999999999

S: 99    ...................................llyiqmelceketLkdwiderk..l  121

                                            ++yiqm+lc+ +tLk+w+ +r+  l

Q: 285   ntrshsvssmqdiailkrpeesqdeapcykpsihvVMYIQMQLCN-TTLKKWLVQRNqiL  343

         999999999***********************************9.*******9999552

S: 122   lesrselvm....rlfkqllegleylHskgliHrdLkpsniFldsdd...qvKigDFgLa  174

         +++ +   +     +fkq++ +l+y+H+kg+ Hrd+kp+niF++++d   q+K gDFgLa

Q: 344   TTKPDLSHVpasfCIFKQIIAALNYIHKKGMLHRDIKPQNIFINDEDqepQIKLGDFGLA  403

         23333333366889*****************************97766899*********

S: 175   talaealkedvkqdaqske......akhtgqvgtklymsPeqleksqYnkkvDifsLGli  228

          a+   ++ +  + + ++        +ht+ vgt+ly+sPeql++++Y+ k Di+s+G++

Q: 404   RAKLSTSSSEPLT-PIHEMpvdflsDEHTSGVGTSLYASPEQLKGETYDDKADIYSAGIV  462

         *988777764444.333334567777**********************************

S: 229   lfeLlypfstemervetltelrdgkipedfddkvpkekkllqkllsrdpkeRpsasellk  288

         l eL+ p+ t  er   ++ lr+ +ip df+ ++p++  ll+ +ls++ + Rpsa++ll

Q: 463   LYELICPLGTTHERTVAINILRKQEIPTDFQRNAPSAVGLLKSILSHEYQTRPSAEQLLL  522

         **********************************************************95

Domain Sequence
(FASTA)

DEIEVIGYGA FGKVYKAINK IDGQVYAVKQ IKCKSNGSEI MPETNKMLRE VQSLASMQHE 60

NIIRYHCAWI EHTPVSEIEQ TVPLRVSINT TPYSTNDTGS FGDYDPVEHE DGKFWQPSSD 120

SSDEDSSCSE EKSSSNTGSL TTDVIFTHGV MKRSTIRRVQ SYIITGVSNA HLSSLSHIES 180

NTRSHSVSSM QDIAILKRPE ESQDEAPCYK PSIHVVMYIQ MQLCNTTLKK WLVQRNQILT 240

TKPDLSHVPA SFCIFKQIIA ALNYIHKKGM LHRDIKPQNI FINDEDQEPQ IKLGDFGLAR 300

AKLSTSSSEP LTPIHEMPVD FLSDEHTSGV GTSLYASPEQ LKGETYDDKA DIYSAGIVLY 360

ELICPLGTTH ERTVAINILR KQEIPTDFQR NAPSAVGLLK SILSHEYQTR PSAEQLLL 418

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006950	; P:response to stress

KEGG

InterPros

IPR015516	; Haem-reg_EIF2A_Kinase.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 2.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013