EKS-CIS-00036

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CIS-00036

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/PLK	334.4	4.5E-100	12	266	255

Status

Unreviewed

Ensembl Protein

ENSCSAVP00000013292

UniProt Accession

H2Z6T1;

Protein Name

Protein Synonyms/Alias

Gene Name

Csa.3490

Gene Synonyms/Alias

Csa.3490;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCSAVG00000007801	ENSCSAVP00000013293	ENSCSAVT00000013443
ENSCSAVG00000007801	ENSCSAVP00000013292	ENSCSAVT00000013442
ENSCSAVG00000007801	ENSCSAVP00000013295	ENSCSAVT00000013445
ENSCSAVG00000007801	ENSCSAVP00000013294	ENSCSAVT00000013444

Organism

Ciona savignyi

Functional Description

Protein Length

922

Protein Sequence
(FASTA)

QMPPYGSSIA DYEVLNLIGR GAFACVYRAR CRQTSRNVAI KMIDKRSMRK SGMVSRVRSE 60

VEIHAQLKHP SILELHHCFE DADHVYLILE LCMKGELNRY LKSQGNTLSE IQVRKFMVQI 120

VEGMLYLHAH GILHRDITLA NMLLDDEQHI KIADFGLATR LALPTDKHFT MCGTPNFISP 180

EIATRSAHGL ESDVWSLGCM LYTFLVGVPP FDTDAVKSTL KNRVVLGNFT VPEDVSEQAS 240

DLIRKLLKMD PNDRISLSAV LDHPFMVCKP GLKCREASVD SGHATMTTTS TNNYSRQGTL 300

HHQPSFTDSE PLPSKPRSCK PSSRHERFPG KSRSNLSYEP GCYKSNVSNY SRPRHPPSPP 360

VRDHPDVEPR SHHESSSSYN YNGINRSASM QNVSQCEVIR PAVDRSSRSA SSRRHKESIM 420

DSVDESQRHH PRTYNNYPTS STRGRPPARH RTPDTDEYKS SKHDSHSSAG TGQRETTSYD 480

KYNSSHDQRS MHKDRAMDYF PKHDRRRNND ASCTGESTQQ QTREPTKPMQ RSDAKPRELP 540

SINTRRLRII RQKAKNSMVS ILSSGEVCLE IVNSKTGSDI VTEVLRVSCD GTSIKVYPPS 600

STSQHGCMLS KRPPEPPPTT VTYEKTNLPD KYHNKYKYLA RFVQLVRSKT PKVTLFTQQA 660

KCMLMENAPD PDLEASFYNG SKVQQSKGKT LIIDAVGKLT TLDNRVVQRF PLDDGCEEIS 720

KLSPEHRNML NHALTSRQKA LDIESAISVA EENGDNDSSY FPITVSRPPK LTADPGEASR 780

PPRSPPPPPP AQPPPSTLPS RSTAMSRSRT GGKPPSIPSP KQDRTRGHTF APLADIDQIS 840

KSLDVPGVGR ASHLCTGDIW VVYQDGSQIL MQSATTTVVY ANSSGRKEKF GQSARLPDYV 900

KEKLSSLPSI VEMLVHAARD SP 922

Nucleotide Sequence
(FASTA)

CAAATGCCGC CCTATGGAAG CTCAATTGCT GACTATGAAG TTCTAAACCT TATTGGACGT 60

GGCGCGTTTG CGTGCGTGTA CCGTGCGCGA TGTCGTCAGA CAAGCCGCAA TGTTGCGATT 120

AAAATGATCG ATAAAAGAAG CATGAGGAAG TCCGGGATGG TTTCGAGGGT TCGGAGTGAG 180

GTTGAGATCC ATGCTCAACT GAAACATCCA TCCATACTGG AACTTCATCA TTGCTTCGAA 240

GATGCAGATC ATGTTTATCT CATCTTGGAG CTCTGCATGA AAGGGGAGCT CAACAGATAT 300

TTGAAGAGCC AAGGCAACAC TTTATCAGAA ATCCAAGTTC GAAAATTCAT GGTGCAAATA 360

GTAGAAGGAA TGTTGTACCT CCACGCACAT GGTATCCTGC ACCGCGATAT AACTCTCGCC 420

AATATGCTCC TCGATGACGA GCAGCACATC AAGATCGCAG ATTTCGGACT CGCTACTCGA 480

CTGGCGCTGC CCACCGACAA ACACTTCACC ATGTGCGGCA CACCCAACTT CATATCCCCA 540

GAGATTGCTA CACGAAGCGC ACACGGCTTG GAGTCGGATG TCTGGTCGCT GGGCTGTATG 600

TTGTACACAT TCCTCGTCGG CGTGCCACCG TTTGACACGG ATGCGGTGAA GAGCACGCTA 660

AAAAACAGAG TGGTGCTCGG CAACTTCACC GTCCCCGAAG ATGTATCGGA ACAAGCATCC 720

GATCTCATCC GGAAATTACT GAAGATGGAT CCCAATGATC GGATCTCTCT CTCAGCCGTG 780

TTGGATCATC CTTTCATGGT ATGTAAACCG GGACTGAAAT GTCGTGAGGC GTCAGTGGAC 840

AGCGGCCACG CTACGATGAC CACAACGTCA ACCAACAACT ACAGTCGGCA AGGCACGTTG 900

CACCACCAGC CCAGCTTCAC CGACTCGGAG CCGTTGCCAT CGAAACCAAG AAGTTGCAAA 960

CCATCCTCGC GCCACGAGCG ATTCCCGGGC AAATCTCGAT CCAACTTGTC GTACGAACCC 1020

GGTTGCTACA AATCGAACGT GAGTAACTAC TCGCGCCCCC GCCACCCCCC ATCGCCCCCC 1080

GTGCGCGATC ACCCCGACGT GGAACCTCGC AGTCACCACG AGTCATCATC ATCGTACAAC 1140

TACAACGGGA TCAACCGATC CGCGTCGATG CAGAACGTCT CGCAATGCGA GGTGATCCGT 1200

CCCGCGGTCG ACCGATCGTC ACGCTCCGCT TCATCGAGAA GACACAAGGA GTCGATCATG 1260

GATTCCGTGG ACGAGTCCCA ACGACATCAC CCCCGGACTT ACAACAACTA CCCCACCTCC 1320

TCCACACGAG GGCGACCACC TGCGAGACAC AGGACACCCG ACACTGATGA ATACAAATCC 1380

TCGAAACATG ATTCACATAG CAGCGCGGGG ACTGGTCAGC GTGAAACGAC GAGCTACGAC 1440

AAATACAACT CATCCCACGA CCAGCGTTCC ATGCATAAGG ACAGAGCGAT GGATTATTTC 1500

CCGAAACATG ATCGTCGGCG AAATAACGAT GCCAGTTGTA CTGGAGAATC AACACAACAA 1560

CAAACACGAG AACCAACGAA ACCCATGCAA CGATCCGATG CAAAACCACG GGAGCTCCCA 1620

AGTATCAACA CTCGACGTCT GCGGATTATC CGACAGAAAG CAAAGAACTC CATGGTGAGC 1680

ATACTATCGA GTGGGGAGGT TTGTTTGGAA ATCGTCAACA GCAAAACAGG AAGTGACATC 1740

GTCACTGAAG TATTAAGGGT GTCGTGTGAC GGGACTTCAA TCAAGGTGTA CCCACCAAGC 1800

AGTACCAGCC AACACGGGTG CATGTTGTCC AAACGACCAC CCGAACCGCC ACCAACCACT 1860

GTCACTTATG AGAAGACCAA TCTACCTGAC AAATACCACA ATAAATACAA GTACTTAGCA 1920

AGGTTTGTTC AATTAGTTCG ATCAAAGACT CCCAAAGTGA CGTTGTTCAC CCAGCAAGCC 1980

AAGTGCATGT TGATGGAGAA TGCACCCGAC CCTGATCTTG AAGCCTCGTT TTATAACGGG 2040

TCCAAAGTCC AGCAAAGCAA GGGGAAAACC CTCATCATCG ACGCAGTGGG CAAGCTGACC 2100

ACACTGGACA ATCGAGTCGT GCAACGATTC CCTCTCGACG ATGGTTGCGA AGAAATCTCC 2160

AAGTTGTCAC CCGAGCATAG GAATATGCTG AATCATGCTC TCACCTCCCG TCAGAAGGCG 2220

CTGGACATCG AGTCAGCAAT TTCGGTCGCA GAGGAGAATG GAGACAACGA CTCGTCATAT 2280

TTTCCAATCA CAGTTTCAAG ACCCCCCAAG CTCACCGCGG ACCCCGGAGA AGCCTCCCGA 2340

CCCCCTCGAT CGCCCCCACC ACCTCCCCCA GCGCAGCCCC CCCCATCCAC TTTACCGAGT 2400

CGGTCCACCG CTATGAGCAG ATCAAGAACC GGGGGGAAAC CCCCATCGAT ACCCTCACCC 2460

AAACAAGACA GAACCAGAGG CCACACATTT GCCCCACTTG CGGATATCGA CCAAATATCG 2520

AAGTCGCTCG ATGTCCCCGG GGTGGGCAGG GCGTCCCACC TGTGCACGGG TGACATATGG 2580

GTCGTGTACC AGGATGGATC CCAGATCCTC ATGCAATCTG CCACCACCAC CGTGGTCTAC 2640

GCCAACTCAT CCGGTCGCAA GGAGAAATTC GGACAATCAG CTCGTCTGCC CGACTATGTG 2700

AAGGAGAAAC TATCAAGTCT CCCATCCATT GTGGAAATGT TAGTTCACGC GGCTCGGGAC 2760

AGCCCA 2766

Domain Profile

S: 1     yergkllGkGgfakcyelkdletkevfavkvvpksllakekqrekvekeieihrslkhkn  60

         ye+ +l+G+G+fa +y++++ +t++++a+k+++k ++ k+ + ++v++e+eih +lkh++

Q: 12    YEVLNLIGRGAFACVYRARCRQTSRNVAIKMIDKRSMRKSGMVSRVRSEVEIHAQLKHPS  71

         78899*******************************************************

S: 61    ivklyeffedkenvylvlelcsrrslaellkrr.kaltepevryylrqivsglkylhekr  119

         i++l+++fed+++vyl+lelc +++l+++lk++ ++l+e +vr ++ qiv+g++ylh +

Q: 72    ILELHHCFEDADHVYLILELCMKGELNRYLKSQgNTLSEIQVRKFMVQIVEGMLYLHAHG  131

         *******************************9989*************************

S: 120   ilhrdlklgnlflneelevkigdfGlatrlekeeerkktlcGtPnyiaPevlskkghsle  179

         ilhrd++l+n++l++e ++ki+dfGlatrl+ + +++ t+cGtPn+i+Pe++++++h+le

Q: 132   ILHRDITLANMLLDDEQHIKIADFGLATRLALPTDKHFTMCGTPNFISPEIATRSAHGLE  191

         ************************************************************

S: 180   vdiWslGcilytllvGkPPfetkelkety.ekikkaeyslPsslskeaksliakllkkeP  238

         +d+WslGc+lyt+lvG PPf+t+++k+t+ ++++  ++++P+++s++a++li+kllk +P

Q: 192   SDVWSLGCMLYTFLVGVPPFDTDAVKSTLkNRVVLGNFTVPEDVSEQASDLIRKLLKMDP  251

         **************************998358****************************

S: 239   eerpsleevlkdefl  253

         ++r+sl++vl+++f+

Q: 252   NDRISLSAVLDHPFM  266

         *************98

Domain Sequence
(FASTA)

YEVLNLIGRG AFACVYRARC RQTSRNVAIK MIDKRSMRKS GMVSRVRSEV EIHAQLKHPS 60

ILELHHCFED ADHVYLILEL CMKGELNRYL KSQGNTLSEI QVRKFMVQIV EGMLYLHAHG 120

ILHRDITLAN MLLDDEQHIK IADFGLATRL ALPTDKHFTM CGTPNFISPE IATRSAHGLE 180

SDVWSLGCML YTFLVGVPPF DTDAVKSTLK NRVVLGNFTV PEDVSEQASD LIRKLLKMDP 240

NDRISLSAVL DHPFM 255

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004713	; F:protein tyrosine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000959	; POLO_box_duplicated_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008266	; Tyr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00659	; POLO_box; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50078	; POLO_BOX; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00109	; PROTEIN_KINASE_TYR; 1.

Prints

Created Date

20-Feb-2013