EKS-CIS-00052

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CIS-00052

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/DDR	383.0	8.8E-115	146	437	292

Status

Unreviewed

Ensembl Protein

ENSCSAVP00000013798

UniProt Accession

H2Z887;

Protein Name

Protein Synonyms/Alias

Gene Name

Csa.1149

Gene Synonyms/Alias

Csa.1149;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCSAVG00000008095	ENSCSAVP00000013801	ENSCSAVT00000013960
ENSCSAVG00000008095	ENSCSAVP00000013800	ENSCSAVT00000013959
ENSCSAVG00000008095	ENSCSAVP00000013799	ENSCSAVT00000013958
ENSCSAVG00000008095	ENSCSAVP00000013796	ENSCSAVT00000013955
ENSCSAVG00000008095	ENSCSAVP00000013797	ENSCSAVT00000013956
ENSCSAVG00000008095	ENSCSAVP00000013798	ENSCSAVT00000013957

Organism

Ciona savignyi

Functional Description

Protein Length

464

Protein Sequence
(FASTA)

IEPTVLPTND NLYLQPRDAV LSPPPPYQQN PEVTNLYHQP EFCRRLLDQP DVTKNTPNLS 60

HYAESNIFMP AVEAQTIQGV SGNNVYAVPW STPPIHKKNK KKLAAGTTSA SASAASTLTA 120

DSYNEEMMGL MSLHGDEPPE FPREKLEVVE QLGEGQFGEV QLCKAHCSLR KLAPAQFKFP 180

GEPDEPVLVA VKVLRSDATT NAKEDFLKEV RVMGHMQDPN IVHLLAVCTS NEPYAMITEY 240

MEYGDLNQYL QSRADKMAND PTCKEAKMFA TNEILIDMSV QIASGMRYLS SHKFVHRDLA 300

TRNCLVDSKH SIRIADFGMS RNMYQSDYYR IQGRAVLPIR WMSWECVLMG KFSSASDVWA 360

FGVTLWEIFS FCQLQPHSSL TDQQVIENMH HIFKRTGEEV HITKPKRCPA TLFNLIHQCW 420

KRQPEDRPTF QQLHSYLLEK KATPKASSRP PPPTTRPPVP APRA 464

Nucleotide Sequence
(FASTA)

ATTGAACCGA CCGTGCTGCC AACAAACGAC AACTTGTATT TGCAACCAAG AGATGCCGTC 60

CTGTCACCAC CGCCACCTTA TCAGCAAAAT CCAGAAGTGA CAAATTTGTA CCATCAACCA 120

GAATTTTGTC GAAGGCTCCT TGATCAACCC GACGTGACGA AAAACACACC TAATTTATCA 180

CACTACGCAG AGTCAAATAT TTTCATGCCA GCTGTGGAAG CCCAGACGAT TCAGGGTGTT 240

TCTGGTAACA ATGTTTACGC TGTCCCGTGG TCAACGCCGC CTATTCATAA AAAGAACAAA 300

AAGAAACTTG CCGCGGGGAC GACAAGTGCG TCAGCTTCAG CAGCAAGTAC CCTGACCGCA 360

GATTCGTACA ACGAAGAAAT GATGGGTCTG ATGTCACTCC ACGGAGACGA GCCTCCGGAA 420

TTTCCACGCG AGAAGTTAGA AGTTGTTGAA CAGCTTGGTG AAGGACAGTT TGGTGAAGTG 480

CAGCTCTGCA AAGCGCATTG CAGTTTGCGT AAACTTGCCC CTGCCCAATT CAAGTTTCCC 540

GGAGAGCCTG ATGAGCCTGT TTTGGTTGCT GTTAAAGTTT TAAGATCCGA CGCAACAACG 600

AACGCAAAAG AGGACTTTTT AAAGGAGGTT CGAGTAATGG GCCACATGCA AGACCCGAAT 660

ATTGTCCACT TACTTGCAGT GTGCACTAGC AACGAGCCTT ACGCCATGAT TACCGAGTAC 720

ATGGAGTATG GCGATCTAAA CCAATACCTA CAATCAAGAG CTGATAAAAT GGCAAACGAC 780

CCTACTTGTA AAGAAGCAAA AATGTTTGCA ACCAATGAAA TACTGATCGA CATGAGCGTA 840

CAAATTGCAT CGGGAATGCG GTATTTATCA TCACACAAGT TCGTGCACCG TGATCTTGCC 900

ACCAGGAACT GCCTGGTCGA CTCCAAACAT TCTATTCGGA TCGCTGACTT CGGAATGTCA 960

CGTAATATGT ACCAGAGTGA TTATTACCGT ATCCAGGGGC GGGCGGTCCT TCCGATTCGA 1020

TGGATGTCGT GGGAGTGCGT TCTCATGGGC AAGTTCAGCA GCGCAAGCGA TGTTTGGGCG 1080

TTCGGAGTTA CTTTGTGGGA AATTTTTTCG TTCTGTCAGC TTCAACCGCA TAGTTCGCTT 1140

ACCGACCAAC AAGTGATAGA AAACATGCAC CACATTTTCA AGCGAACAGG AGAGGAGGTG 1200

CATATTACGA AACCCAAACG ATGTCCAGCA ACACTTTTTA ACCTAATCCA CCAATGTTGG 1260

AAGCGGCAAC CGGAGGACCG ACCTACCTTT CAACAGCTTC ATAGTTATTT GTTGGAGAAA 1320

AAAGCTACTC CAAAAGCATC TAGCCGCCCA CCACCGCCGA CAACGAGACC TCCCGTTCCA 1380

GCACCTCGTG CCTGA 1395

Domain Profile

S: 1     LlikeklGeGkfgevklCeve.gledlkekd.....skgsallvavkslredanknarkd  54

         L ++e+lGeG+fgev+lC+ + +l++l   +     +  +++lvavk+lr+da++na++d

Q: 146   LEVVEQLGEGQFGEVQLCKAHcSLRKLAPAQfkfpgEPDEPVLVAVKVLRSDATTNAKED  205

         6789**************9873467777666778888899********************

S: 55    flkeikilsrlkdPnivrllgvcvrdeplclileyvenGdlnqflsehe...aedselak  111

         flke++++++++dPniv+ll+vc+ +ep+ +i+ey+e+Gdlnq+l+++    a+d + ++

Q: 206   FLKEVRVMGHMQDPNIVHLLAVCTSNEPYAMITEYMEYGDLNQYLQSRAdkmANDPTCKE  265

         *********************************************988766655555555

S: 112   ektl.syellvsiatqiasglkyLeslnfvhrdlatrnclvgeeftvkiadfglsrslya  170

         +k     e+l+ ++ qiasg++yL+s +fvhrdlatrnclv+ + +++iadfg+sr++y

Q: 266   AKMFaTNEILIDMSVQIASGMRYLSSHKFVHRDLATRNCLVDSKHSIRIADFGMSRNMYQ  325

         5554156789**************************************************

S: 171   gdyyrvqGravlPiRwmawesillgkfttasDvWafgvtlweiltlcreqPyeeltdeqv  230

         +dyyr+qGravlPiRwm+we++l+gkf+ asDvWafgvtlwei+++c+ qP++ ltd+qv

Q: 326   SDYYRIQGRAVLPIRWMSWECVLMGKFSSASDVWAFGVTLWEIFSFCQLQPHSSLTDQQV  385

         ************************************************************

S: 231   ienagelfrdqkrkvvlsrPavcpselyelllrCwrrdeseRPsfeelhkll  282

         ien+ ++f+  +++v +++P+ cp +l++l+ +Cw+r+ ++RP+f++lh +l

Q: 386   IENMHHIFKRTGEEVHITKPKRCPATLFNLIHQCWKRQPEDRPTFQQLHSYL  437

         *************************************************987

Domain Sequence
(FASTA)

LEVVEQLGEG QFGEVQLCKA HCSLRKLAPA QFKFPGEPDE PVLVAVKVLR SDATTNAKED 60

FLKEVRVMGH MQDPNIVHLL AVCTSNEPYA MITEYMEYGD LNQYLQSRAD KMANDPTCKE 120

AKMFATNEIL IDMSVQIASG MRYLSSHKFV HRDLATRNCL VDSKHSIRIA DFGMSRNMYQ 180

SDYYRIQGRA VLPIRWMSWE CVLMGKFSSA SDVWAFGVTL WEIFSFCQLQ PHSSLTDQQV 240

IENMHHIFKR TGEEVHITKP KRCPATLFNL IHQCWKRQPE DRPTFQQLHS YL 292

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004713	; F:protein tyrosine kinase activity
GO:0007155	; P:cell adhesion

KEGG

InterPros

IPR000421	; Coagulation_fac_5/8-C_type_dom.
IPR008979	; Galactose-bd-like.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.
IPR008266	; Tyr_kinase_AS.
IPR020635	; Tyr_kinase_cat_dom.

Pfam

PF00754	; F5_F8_type_C; 1.
PF07714	; Pkinase_Tyr; 1.

SMARTs

SM00231	; FA58C; 1.
SM00219	; TyrKc; 1.

Prosites

PS01285	; FA58C_1; 1.
PS01286	; FA58C_2; 1.
PS50022	; FA58C_3; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00109	; PROTEIN_KINASE_TYR; 1.

Prints

PR00109

; TYRKINASE.

Created Date

20-Feb-2013