EKS-CIS-00012

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CIS-00012

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE7	345.7	1.7E-103	67	341	275

Status

Unreviewed

Ensembl Protein

ENSCSAVP00000014411

UniProt Accession

H2Z9Z6;

Protein Name

Protein Synonyms/Alias

Gene Name

Csa.8484

Gene Synonyms/Alias

Csa.8484;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCSAVG00000008439	ENSCSAVP00000014411	ENSCSAVT00000014576

Organism

Ciona savignyi

Functional Description

Protein Length

365

Protein Sequence
(FASTA)

VEMPPKRKIN ALNLKIGGSP SPDQISDLGK KMDELNIDET QRKRLDQFIK QKQKVGLMEN 60

AQNSDFTKKG ELGVGNGGVV HLVVHNATGF VMARKLIHLE VKPAILNQIT RELQVLHDCR 120

SPYIVGYYGT FYSDGEISIC MESMDAGSLD LVLKKAGKIP EVILGKVSKA VILGLKYLRE 180

ERSIIHRDVK PSNILVNSRG EIKLCDFGVS GQLIDSMANS FVGTRSYMAP ERLQGSKYTI 240

LSDIWSLGLS LIEMAIGRFP IPPPTPAQVT AMFSNDGKKG GDFGPRPMAI FELLDYIVNE 300

PAPKLPRGHF SDEFCDFVAN CMKKDPKERS DLAFLMESSF VTNVKLTQYE FATWVCSTMD 360

LKLPS 365

Nucleotide Sequence
(FASTA)

GTAGAAATGC CACCTAAGCG TAAAATAAAT GCCCTCAATC TTAAGATTGG GGGTTCCCCT 60

AGCCCTGACC AGATATCTGA TCTGGGAAAA AAGATGGACG AGCTGAATAT TGATGAAACG 120

CAGAGAAAAA GATTGGACCA ATTTATCAAG CAGAAACAGA AGGTGGGACT GATGGAAAAT 180

GCCCAGAATT CTGATTTCAC GAAGAAGGGT GAATTGGGTG TTGGTAATGG AGGAGTAGTT 240

CATCTTGTCG TACATAACGC TACTGGTTTC GTGATGGCAC GTAAGCTCAT TCACTTGGAA 300

GTGAAGCCCG CAATTTTAAA TCAGATCACA AGAGAATTGC AGGTTCTGCA TGACTGCCGA 360

AGCCCCTATA TTGTTGGTTA TTACGGGACC TTTTATAGCG ATGGTGAAAT CAGTATATGC 420

ATGGAGAGTA TGGACGCTGG TTCACTGGAT TTGGTTTTGA AGAAAGCCGG AAAAATTCCT 480

GAAGTTATTC TCGGCAAAGT GAGCAAAGCT GTGATTCTGG GTCTAAAATA TTTAAGAGAA 540

GAGAGAAGCA TAATTCACCG GGATGTGAAG CCATCCAATA TCCTTGTCAA CTCCAGAGGA 600

GAGATCAAAT TATGCGACTT TGGCGTGAGC GGGCAACTGA TAGACTCAAT GGCAAATTCG 660

TTTGTGGGAA CTCGATCCTA CATGGCTCCG GAACGTTTAC AAGGCTCAAA GTACACAATT 720

TTGTCCGACA TTTGGTCTCT TGGACTCTCG CTAATCGAAA TGGCAATTGG ACGGTTCCCC 780

ATACCACCAC CCACCCCCGC ACAGGTGACA GCAATGTTCA GCAACGATGG GAAAAAAGGA 840

GGTGACTTTG GCCCGCGGCC GATGGCAATA TTCGAGTTAT TGGATTATAT TGTGAATGAG 900

CCTGCACCAA AGCTACCACG AGGTCATTTC AGTGATGAGT TTTGTGATTT CGTCGCCAAC 960

TGCATGAAAA AAGACCCAAA GGAAAGATCA GACCTTGCGT TTCTAATGGA GAGTTCATTT 1020

GTTACCAATG TAAAGCTCAC TCAATATGAG TTTGCAACGT GGGTGTGTTC AACAATGGAC 1080

TTGAAGTTAC CAAGT 1095

Domain Profile

S: 2     ekleelGaGnggvVekvlhkksgkilavKtirleikkeeqkqilrelevlkkssnspyiv  61

         +k +elG GnggvV+ v+h+ +g ++a+K i+le+k+++ +qi rel+vl+ + +spyiv

Q: 67    TKKGELGVGNGGVVHLVVHNATGFVMARKLIHLEVKPAILNQITRELQVLHDC-RSPYIV  125

         57899************************************************.******

S: 62    kfyGafvsegdvsicmelmdgtsldkvlkkvlekkkripekvlgkiavavvkaleylkek  121

         ++yG+f+s+g++sicme md +sld vlkk    +++ipe +lgk++ av+ +l+yl+e+

Q: 126   GYYGTFYSDGEISICMESMDAGSLDLVLKK----AGKIPEVILGKVSKAVILGLKYLREE  181

         ****************************99....8*************************

S: 122   lkiiHRDvKPsNiLvnskGevKlCDFGvsgqlvdsiAksavGtksYmaPEriegkkkYsv  181

          +iiHRDvKPsNiLvns+Ge+KlCDFGvsgql+ds+A+s+vGt+sYmaPEr++g +kY++

Q: 182   RSIIHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQG-SKYTI  240

         ******************************************************.*****

S: 182   ksdvWslGltlvelatgrypyeklke.......................ilellkaivne  218

          sd+WslGl+l+e+a+gr+p+++++                        i+ell++ivne

Q: 241   LSDIWSLGLSLIEMAIGRFPIPPPTPaqvtamfsndgkkggdfgprpmaIFELLDYIVNE  300

         **********************998889********************************

S: 219   eppklpeeefseefqefvskClkkdekeRpklkellkhafi  259

         ++pklp+ +fs+ef++fv++C+kkd+keR++l  l++ +f+

Q: 301   PAPKLPRGHFSDEFCDFVANCMKKDPKERSDLAFLMESSFV  341

         *************************************9995

Domain Sequence
(FASTA)

TKKGELGVGN GGVVHLVVHN ATGFVMARKL IHLEVKPAIL NQITRELQVL HDCRSPYIVG 60

YYGTFYSDGE ISICMESMDA GSLDLVLKKA GKIPEVILGK VSKAVILGLK YLREERSIIH 120

RDVKPSNILV NSRGEIKLCD FGVSGQLIDS MANSFVGTRS YMAPERLQGS KYTILSDIWS 180

LGLSLIEMAI GRFPIPPPTP AQVTAMFSND GKKGGDFGPR PMAIFELLDY IVNEPAPKLP 240

RGHFSDEFCD FVANCMKKDP KERSDLAFLM ESSFV 275

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013