EPS-CIS-00022

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-CIS-00022

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/PTEN	147.2	6.3E-43	435	593	159

Status

Unreviewed

Ensembl Protein

ENSCSAVP00000014504

UniProt Accession

H2ZA86;

Protein Name

Protein Synonyms/Alias

Gene Name

Csa.10856

Gene Synonyms/Alias

Csa.10856;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCSAVG00000008491	ENSCSAVP00000014507	ENSCSAVT00000014672
ENSCSAVG00000008491	ENSCSAVP00000014500	ENSCSAVT00000014665
ENSCSAVG00000008491	ENSCSAVP00000014501	ENSCSAVT00000014666
ENSCSAVG00000008491	ENSCSAVP00000014502	ENSCSAVT00000014667
ENSCSAVG00000008491	ENSCSAVP00000014503	ENSCSAVT00000014668
ENSCSAVG00000008491	ENSCSAVP00000014504	ENSCSAVT00000014669
ENSCSAVG00000008491	ENSCSAVP00000014505	ENSCSAVT00000014670
ENSCSAVG00000008491	ENSCSAVP00000014506	ENSCSAVT00000014671

Organism

Ciona savignyi

Functional Description

Protein Length

845

Protein Sequence
(FASTA)

MSFFKSALNF VSGTSSESFV GSTVELGEQQ LNVNCAIAEG GFAIVYEATD AAGTKYALKR 60

LLSQEASKKK EIIREIQFLK RLSGHPNIIQ YISAATISKE ESGQAHDEFL LCTEFCEGGQ 120

LVDVMRRLGG PMPLDQIIKA FYQTCSAVSH LHKQQLPVIH RDLKVENLLL TANGILKLCD 180

FGSATTASHY PDNTWTAAKR GQVEDEILRN TTPMYRTPEM IDMYSNYPIN EMQDIWALGC 240

ILYLLCFNKH PFEDSARLAI LNANFTIPTT DKKYKMLHPL IKSILQINPN NRPPAVVIVE 300

QLSEFAASLS IDPKSSIDLV TCLNFPVCIL LGFYPTPLDT LLGHYLISLL TAYLIQRNFN 360

SGATALCMIQ SKGLFVEKSH MLFENVYKFH EQSFTEPNND ASGLFSMMKG GAGKLLTNIK 420

DTSSKVVQSV ASYAKSDLDV TYITSRLAVM SYPAEGMEAA YKNNIESVCA YFDAKHRDHY 480

AVYNLSTRQY DSARFHHRVV NMGWATKHAP TLKNLLTLCK HIIQWLKKDP LNVAVIHCLD 540

GKAQSAVVAC SVLVICGLFN TADASLFMFS IKRMPPGISP SYKRYIEYIC SMKDIEKPLS 600

TVPHAYQVTI HQIELAPVPL FNRMRNGCRP FCEVYVGENR VMSTATDYES MRWFADTDGK 660

VLLDIGAKVG GGTNSDISVS VYHARQILGG KLTLQAKQTG IKMFQLQFNA GFVPPTATKV 720

HFQTYDLDAC DIQEKYPDGF RVTLHVQVHV DADATASNMW DGMLTKGVTP KLLFSTREEQ 780

SEVLQKFGHK EDELQPSITY TLSNTPHDLP SKPSNATHEP NEPEQPRNGQ NAASSGNIFD 840

TLDWH 845

Nucleotide Sequence
(FASTA)

ATGTCATTTT TTAAATCTGC TTTAAATTTT GTGAGCGGAA CGAGTAGCGA AAGCTTTGTT 60

GGATCAACCG TAGAACTTGG TGAACAACAA TTAAATGTCA ACTGTGCGAT TGCGGAAGGT 120

GGTTTTGCAA TTGTGTATGA GGCAACTGAT GCTGCTGGAA CCAAATATGC TTTAAAGCGA 180

CTTCTTTCAC AAGAAGCGAG TAAAAAAAAA GAAATTATTC GAGAGATCCA ATTCTTAAAG 240

CGATTGTCTG GTCACCCAAA CATTATCCAA TACATATCGG CTGCCACGAT ATCAAAGGAG 300

GAATCGGGAC AAGCACATGA TGAATTTTTA CTTTGTACTG AATTTTGTGA AGGTGGACAG 360

CTGGTTGATG TTATGAGAAG GTTAGGGGGT CCGATGCCCT TGGATCAAAT CATCAAAGCT 420

TTTTATCAGA CATGCTCAGC AGTGTCACAT CTTCACAAAC AACAGCTTCC AGTTATTCAC 480

AGAGATTTAA AGGTTGAAAA CTTGCTCCTA ACTGCGAATG GAATACTGAA GCTTTGCGAC 540

TTTGGAAGTG CAACCACTGC TTCCCACTAT CCTGATAATA CTTGGACAGC TGCTAAGAGG 600

GGACAGGTTG AAGATGAGAT TCTACGTAAC ACAACTCCAA TGTACAGGAC TCCTGAAATG 660

ATAGACATGT ACAGCAACTA TCCTATTAAT GAGATGCAAG ACATCTGGGC ACTTGGTTGT 720

ATTCTCTACC TGTTGTGTTT CAACAAACAC CCGTTTGAAG ATTCTGCTCG GCTTGCTATT 780

CTGAACGCAA ATTTTACAAT TCCAACAACG GACAAGAAAT ATAAGATGCT TCATCCACTG 840

ATAAAATCCA TCCTTCAAAT CAACCCCAAC AACCGCCCCC CAGCTGTTGT GATTGTGGAG 900

CAGCTTTCCG AATTTGCAGC CTCATTATCA ATAGACCCTA AATCTTCAAT TGATTTAGTA 960

ACGTGCTTGA ATTTTCCTGT TTGTATCTTG CTTGGATTCT ACCCAACGCC ACTGGATACA 1020

TTGCTTGGCC ACTATTTAAT ATCTTTACTG ACTGCGTACT TAATACAAAG AAATTTTAAT 1080

TCCGGAGCTA CCGCACTATG TATGATCCAG AGCAAAGGTT TATTTGTTGA AAAATCTCAC 1140

ATGCTTTTCG AAAATGTTTA CAAGTTTCAT GAACAAAGCT TCACTGAACC AAATAATGAT 1200

GCATCTGGGT TGTTCAGTAT GATGAAAGGC GGGGCTGGTA AATTGCTCAC CAATATCAAA 1260

GATACTTCGA GCAAAGTAGT GCAGTCAGTG GCTAGCTATG CAAAATCAGA TCTTGATGTC 1320

ACTTATATCA CCTCAAGATT GGCAGTTATG TCTTACCCGG CTGAAGGCAT GGAAGCAGCA 1380

TATAAGAACA ACATTGAGTC GGTCTGTGCT TACTTTGACG CCAAGCACCG GGATCATTAC 1440

GCAGTCTACA ACTTGTCCAC TCGTCAATAT GATTCAGCCA GATTTCATCA TCGGGTTGTC 1500

AACATGGGTT GGGCGACTAA ACATGCTCCC ACGCTTAAAA ACCTTCTTAC ACTTTGCAAA 1560

CACATCATAC AGTGGTTGAA AAAGGACCCT CTTAATGTTG CTGTTATCCA TTGTCTTGAT 1620

GGCAAAGCAC AATCTGCAGT TGTAGCATGC TCTGTACTTG TCATTTGTGG ATTATTCAAC 1680

ACAGCTGATG CTTCACTCTT TATGTTCAGT ATAAAACGGA TGCCACCTGG TATCTCCCCA 1740

TCTTACAAAA GGTACATTGA ATACATATGC AGTATGAAGG ACATAGAAAA GCCTTTATCA 1800

ACTGTTCCAC ATGCTTATCA AGTCACTATC CATCAAATTG AGTTGGCACC TGTTCCACTG 1860

TTCAATAGAA TGCGAAATGG TTGTCGACCC TTTTGTGAGG TGTATGTGGG TGAAAATCGT 1920

GTCATGTCAA CCGCCACTGA CTATGAATCA ATGAGGTGGT TTGCTGACAC CGATGGGAAA 1980

GTGTTGTTAG ATATCGGTGC CAAAGTGGGC GGGGGTACAA ACTCCGATAT CTCGGTATCT 2040

GTGTACCACG CTCGGCAAAT TCTTGGTGGG AAGTTGACAC TCCAAGCAAA GCAGACCGGT 2100

ATCAAGATGT TCCAGCTTCA GTTCAATGCT GGGTTTGTTC CACCAACTGC TACTAAAGTC 2160

CATTTCCAAA CATACGATTT GGATGCATGT GATATTCAGG AAAAATACCC GGATGGTTTC 2220

CGTGTGACTT TGCATGTGCA AGTTCATGTT GATGCCGATG CCACAGCATC TAATATGTGG 2280

GATGGGATGT TAACAAAAGG GGTCACCCCT AAACTGCTTT TTTCAACCAG AGAAGAACAA 2340

AGTGAAGTCT TACAAAAATT TGGACACAAA GAGGATGAGT TACAACCATC CATCACTTAC 2400

ACTCTTTCCA ATACGCCACA TGATTTGCCA AGTAAACCCT CCAATGCCAC ACATGAACCA 2460

AATGAGCCAG AACAGCCAAG AAACGGACAA AATGCAGCGA GTAGCGGAAA TATATTTGAC 2520

ACTCTAGATT GGCAT 2535

Domain Profile

S: 7     gfdldltyvteriiavsfPaeareevyrnnlrevvrlldskhrnkyklynlcserrydlt  66

         + dld+ty+t r+  +s+Pae+ e  y+nn++ v   +d khr++y +ynl s r+yd +

Q: 435   KSDLDVTYITSRLAVMSYPAEGMEAAYKNNIESVCAYFDAKHRDHYAVYNL-STRQYDSA  493

         579************************************************.********

S: 67    klnakvaefgiedlnaPaleklvsickeldeWlseddenvvvlhckggkgrlGvivcayl  126

         +++ +v+++g+  ++aP+l++l ++ck++ +Wl +d+ nv+v+hc  gk +  v+ c+ l

Q: 494   RFHHRVVNMGWATKHAPTLKNLLTLCKHIIQWLKKDPLNVAVIHCLDGKAQSAVVACSVL  553

         ************************************************************

S: 127   laseisakadealdtfgerrtredkvagvkqPsqrryvsyfsqll  171

         +  + + +ad +l +f+ +r+          Ps +ry++y + ++

Q: 554   VICGLFNTADASLFMFSIKRMPP-----GISPSYKRYIEYICSMK  593

         ******************99764.....459*********98876

Domain Sequence
(FASTA)

KSDLDVTYIT SRLAVMSYPA EGMEAAYKNN IESVCAYFDA KHRDHYAVYN LSTRQYDSAR 60

FHHRVVNMGW ATKHAPTLKN LLTLCKHIIQ WLKKDPLNVA VIHCLDGKAQ SAVVACSVLV 120

ICGLFNTADA SLFMFSIKRM PPGISPSYKR YIEYICSMK 159

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR008973	; C2_Ca/lipid-bd_dom_CaLB.
IPR001623	; DnaJ_N.
IPR011009	; Kinase-like_dom.
IPR014019	; Phosphatase_tensin-typ.
IPR000719	; Prot_kinase_cat_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR014020	; Tensin_phosphatase_C2-dom.

Pfam

PF00226	; DnaJ; 1.
PF00069	; Pkinase; 1.
PF10409	; PTEN_C2; 1.

SMARTs

SM00271

; DnaJ; 1.

Prosites

PS51182	; C2_TENSIN; 1.
PS50076	; DNAJ_2; 1.
PS51181	; PPASE_TENSIN; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013