EKS-CIS-00194

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CIS-00194

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/RSKb	318.8	2.6E-95	428	705	278

Status

Unreviewed

Ensembl Protein

ENSCSAVP00000015522

UniProt Accession

H2ZD55;

Protein Name

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCSAVG00000009110	ENSCSAVP00000015522	ENSCSAVT00000015700
ENSCSAVG00000009110	ENSCSAVP00000015521	ENSCSAVT00000015699
ENSCSAVG00000009110	ENSCSAVP00000015520	ENSCSAVT00000015698

Organism

Ciona savignyi

Functional Description

Protein Length

788

Protein Sequence
(FASTA)

ANLTGHVEKV GLDSFELLKV LGTGAYGKVF LVRKACGHDM GKLYAMKVLK KASIVTKQKT 60

TEHTMTERQV LEAVRQSPFL VTLHYAFQTN SRLHLILDYV NGGEMFTHLN IREKFTEAEV 120

QLFSAEILLA LEHLHKVRNK QIWLAIYPPK WLLMLNYLNR LLNFKLGIVY RDIKLENILL 180

DSDGHVVLTD FGLSKEFINE GDRAYSFCGT IEYMAPEVIK SNGAGHDFAV DFWSLGVLMY 240

ELMTGASPFT VEGEKNSQSE VSRRILYKHP PVPKKLSPPA LDIILKLLDK NPQTRLGCGN 300

RGINDIKDHS FYKSMDWEKV ARKDVPAPFK PVIANDEDTS NFADEFTLMP VNYSPAPTPA 360

PNPSCPFKGY SFVSPSVVFG RQHVLSDDLL QPMRNTGRPS PSYLQKVAHL GRGTNSEFFH 420

LFELDLVTPP LGDGSFSVCR KCVELSTGKE FAVKIISRRW ELQSMLELRT LTQCQGHPNI 480

VKLYNIYQDK HHTYIVMELL HGGELLSLIR DHPLFTEAEA SIIMKQIISA VAFMHDKGIV 540

HRDLKPENII FVQAPTDHNN NSPAKQLHLK IVDFGFARLK PNAGPGASVS LKTPVFTLQY 600

AAPEVLQLSG FVGATNAQGY DESCDLWSIG VILYAVLSGA VPFVSDGQAL KAAEIMTRIT 660

QGEFTFDGPS WQNVSEEARR LVHGLLTVDP SKRLKISDLL ASPWVQGACA PTTPLLSPGV 720

LSPGPRATNF FNATMKAYHM ASKGGFQLSA VTNAPIAKRR NRKRTCKQRD GSDTRSSGSS 780

TDSPVTTS 788

Nucleotide Sequence
(FASTA)

GCAAATCTCA CAGGGCATGT GGAAAAAGTT GGCTTGGACA GTTTTGAGCT ATTGAAAGTC 60

TTAGGAACTG GAGCATATGG TAAAGTGTTT TTGGTCAGAA AAGCTTGTGG TCATGATATG 120

GGGAAACTAT ATGCTATGAA GGTTCTGAAA AAAGCCTCTA TTGTAACAAA ACAAAAAACA 180

ACCGAGCACA CAATGACAGA AAGACAGGTT TTGGAGGCTG TAAGGCAATC ACCATTCCTA 240

GTTACACTTC ATTATGCATT TCAAACCAAT TCAAGATTAC ATCTTATCCT GGATTATGTC 300

AACGGAGGGG AAATGTTTAC GCATTTGAAT ATCAGGGAAA AGTTCACTGA AGCGGAAGTT 360

CAGCTTTTCA GTGCTGAGAT TCTTCTAGCC TTGGAGCATT TGCATAAAGT AAGAAATAAG 420

CAAATATGGC TTGCTATATA TCCACCCAAA TGGTTACTGA TGCTTAATTA TTTAAATAGA 480

CTTTTAAACT TTAAACTTGG GATCGTGTAC CGCGACATAA AATTGGAAAA TATTTTGCTG 540

GATTCTGATG GACATGTGGT TTTAACTGAC TTTGGTCTGA GCAAGGAATT TATAAACGAA 600

GGTGATAGAG CCTACTCATT CTGTGGTACC ATTGAATACA TGGCACCTGA AGTTATCAAA 660

AGTAACGGGG CCGGACACGA TTTTGCCGTT GATTTTTGGA GCCTTGGTGT GCTGATGTAC 720

GAACTAATGA CCGGGGCATC TCCGTTTACA GTGGAAGGAG AAAAAAACAG TCAATCTGAA 780

GTTTCCAGAC GGATATTATA TAAACACCCT CCAGTACCAA AAAAGTTATC CCCGCCAGCA 840

CTTGATATTA TATTGAAACT TCTTGACAAG AACCCTCAGA CACGATTGGG TTGTGGAAAC 900

AGAGGCATAA ATGATATAAA AGATCATTCT TTTTATAAGT CAATGGATTG GGAGAAAGTG 960

GCCCGCAAAG ACGTTCCCGC CCCTTTCAAG CCGGTGATCG CAAACGATGA AGACACCAGT 1020

AATTTCGCCG ATGAATTCAC ATTGATGCCA GTCAACTATT CTCCTGCACC CACCCCTGCA 1080

CCCAACCCAT CATGTCCTTT CAAGGGTTAT TCATTTGTGT CTCCTTCTGT CGTGTTCGGT 1140

CGGCAACACG TTTTGTCCGA CGACCTGCTT CAACCGATGC GCAACACTGG CCGCCCCTCC 1200

CCCAGCTATC TCCAGAAGGT GGCGCACCTG GGACGCGGGA CCAACAGCGA GTTTTTCCAC 1260

CTGTTTGAGC TCGATCTCGT TACGCCCCCT CTGGGCGACG GGAGTTTTTC AGTTTGTCGA 1320

AAGTGCGTTG AGCTATCAAC AGGCAAGGAA TTCGCCGTAA AAATAATAAG CAGAAGATGG 1380

GAACTTCAAT CAATGCTTGA ACTAAGAACC CTCACACAAT GCCAGGGGCA CCCCAATATA 1440

GTCAAGTTGT ACAATATCTA TCAGGATAAG CATCATACCT ACATAGTCAT GGAACTTCTG 1500

CATGGCGGCG AACTGCTGTC ACTTATACGT GACCACCCCC TGTTCACCGA GGCAGAGGCT 1560

AGTATCATAA TGAAGCAAAT CATATCAGCC GTGGCTTTCA TGCATGACAA AGGGATTGTG 1620

CACCGTGACT TGAAACCCGA GAACATTATT TTCGTGCAAG CGCCAACCGA CCACAACAAC 1680

AACTCCCCGG CGAAACAACT GCATCTCAAA ATCGTCGATT TCGGCTTCGC TCGGCTCAAG 1740

CCGAACGCTG GACCTGGCGC ATCGGTGTCG CTGAAAACGC CGGTTTTCAC GCTACAGTAC 1800

GCTGCCCCCG AAGTCCTGCA GTTGTCGGGG TTCGTCGGCG CCACAAATGC GCAGGGTTAT 1860

GATGAGTCAT GTGATCTTTG GAGCATAGGT GTGATTCTGT ACGCCGTGTT ATCCGGTGCC 1920

GTACCGTTCG TGAGCGACGG ACAGGCTCTC AAAGCAGCCG AGATTATGAC GCGTATCACG 1980

CAAGGGGAAT TCACCTTCGA TGGACCGTCG TGGCAGAATG TATCAGAAGA GGCACGCAGG 2040

CTTGTGCATG GTCTTTTGAC CGTCGATCCT TCTAAGCGGT TGAAGATATC GGATCTACTG 2100

GCGAGTCCGT GGGTTCAGGG GGCATGTGCC CCTACCACCC CACTCCTTAG CCCCGGGGTG 2160

CTGTCACCCG GCCCCCGAGC CACGAACTTC TTCAACGCAA CGATGAAAGC CTACCACATG 2220

GCGAGTAAAG GAGGCTTCCA GCTTTCCGCT GTCACGAACG CGCCGATCGC GAAACGGCGC 2280

AACCGAAAAC GAACCTGCAA ACAGCGGGAT GGCTCCGACA CTAGGAGTAG CGGCAGCTCG 2340

ACTGACAGTC CAGTTACCAC GTCA 2364

Domain Profile

S: 4     kedlGvGsysvckrcvhkatnqefavkiidks.krdtseeieillryeqhpnivtlkdvy  62

           +lG Gs+svc++cv+ +t++efavkii+++ + ++  e+  l+++++hpniv+l ++y

Q: 428   TPPLGDGSFSVCRKCVELSTGKEFAVKIISRRwELQSMLELRTLTQCQGHPNIVKLYNIY  487

         5689****************************99**************************

S: 63    ddgkyvylvlellkGGelldrikkkkffsereasailrtlvkaveylheqGvvhrdlkpe  122

         +d++++y+v+ell+GGell  i+ +  f+e eas i++++ +av ++h++G+vhrdlkpe

Q: 488   QDKHHTYIVMELLHGGELLSLIRDHPLFTEAEASIIMKQIISAVAFMHDKGIVHRDLKPE  547

         ************************************************************

S: 123   nilyv....desdnaes....ikiidfGfaklkrae.ng...llktpcytlnfvapevl.  169

         ni++v    d+++n+++    +ki+dfGfa+lk++  +g    lktp +tl+++apevl

Q: 548   NIIFVqaptDHNNNSPAkqlhLKIVDFGFARLKPNAgPGasvSLKTPVFTLQYAAPEVLq  607

         ****733335555554334449**********98642334458***************94

S: 170   ........krqGydeacdlwslGvllytmlaGyvpf.angpedtaeeilakikeGkfsls  220

                 + qGyde+cdlws+Gv+ly +l+G vpf ++g+  +a+ei+++i +G+f+++

Q: 608   lsgfvgatNAQGYDESCDLWSIGVILYAVLSGAVPFvSDGQALKAAEIMTRITQGEFTFD  667

         44444433479*************************66788889****************

S: 221   Geawdsvseeakdlvsklltvdpakrlkleqllkhswl  258

         G +w++vseea+ lv++lltvdp+krlk+++ll ++w+

Q: 668   GPSWQNVSEEARRLVHGLLTVDPSKRLKISDLLASPWV  705

         *************************************7

Domain Sequence
(FASTA)

TPPLGDGSFS VCRKCVELST GKEFAVKIIS RRWELQSMLE LRTLTQCQGH PNIVKLYNIY 60

QDKHHTYIVM ELLHGGELLS LIRDHPLFTE AEASIIMKQI ISAVAFMHDK GIVHRDLKPE 120

NIIFVQAPTD HNNNSPAKQL HLKIVDFGFA RLKPNAGPGA SVSLKTPVFT LQYAAPEVLQ 180

LSGFVGATNA QGYDESCDLW SIGVILYAVL SGAVPFVSDG QALKAAEIMT RITQGEFTFD 240

GPSWQNVSEE ARRLVHGLLT VDPSKRLKIS DLLASPWV 278

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 3.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 2.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 2.
PS50011	; PROTEIN_KINASE_DOM; 2.
PS00108	; PROTEIN_KINASE_ST; 2.

Prints

Created Date

20-Feb-2013