EKS-CIS-00231

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CIS-00231

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/PKD	485.9	2.3E-146	357	613	257

Status

Unreviewed

Ensembl Protein

ENSCSAVP00000016124

UniProt Accession

H2ZEV9;

Protein Name

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCSAVG00000009491	ENSCSAVP00000016124	ENSCSAVT00000016305
ENSCSAVG00000009491	ENSCSAVP00000016125	ENSCSAVT00000016306
ENSCSAVG00000009491	ENSCSAVP00000016126	ENSCSAVT00000016307
ENSCSAVG00000009491	ENSCSAVP00000016130	ENSCSAVT00000016311
ENSCSAVG00000009491	ENSCSAVP00000016131	ENSCSAVT00000016312
ENSCSAVG00000009491	ENSCSAVP00000016128	ENSCSAVT00000016309
ENSCSAVG00000009491	ENSCSAVP00000016127	ENSCSAVT00000016308
ENSCSAVG00000009491	ENSCSAVP00000016129	ENSCSAVT00000016310

Organism

Ciona savignyi

Functional Description

Protein Length

649

Protein Sequence
(FASTA)

QQIHLFQHQP NHDNILKVMK SSDEMKDGAL IEVVLSGNLH FLIRPHTLSV HSYRSPAFCD 60

YCGEMLWGIV RQGLRCDGCG QNYHKRCAYK IPNDCTLVRK RKASVSASVN TWNGSTLSLQ 120

DSVSSSVSVH SYTRPTVCMQ CKKLLRGFFK QGVQCKGMSY LTLPRKTPRS LRAIHYVLKH 180

ALQAHSYCGP ASLYISSSDA PNIPLMRVVQ SIKQTKKRSS TVLKEGWLIH FTNKDSVRRR 240

HYWRLDSKSI TLYRSETGAN YFKEIELSDI LSILMVTRLL PGEPLHFFKI LTSGLELLVS 300

DDSGEIYLLL RRLWTMNIDN HMNIHRSENV VDWHTQVYQA LTPVDRKQDS TSGIYQVFPD 360

EVLGSGQFGT VYGGKHRKRG FDVAIKVVDK LRFQHKEESQ LRHEVQILEW LDHPGIVKLF 420

NMFETPEQVF VVMEKLRGDM LEMILSSEKG RLPERITKFL ISQILIALRY LHKQNIVHCD 480

LKPENVLLSS DDAFPQLKLC DFGFARIIGQ KSFRRSVVGT PAYLAPEVLR KECYNRSLDM 540

WSVGVIIYVS LSGTFPFNED EDINQQIQNA AFMYPAHPWS GISHDSVDLI GSLLQVKKRK 600

RPSVDKALSH IWLQDYQCWQ DLRQLEQVVG KRYLTHESDD DRWSAYQRE 649

Nucleotide Sequence
(FASTA)

CAGCAGATTC ATCTCTTTCA GCATCAGCCA AATCATGACA ATATACTCAA AGTTATGAAA 60

TCTTCAGATG AAATGAAAGA TGGAGCTCTC ATTGAAGTTG TTTTGTCAGG TAATTTACAC 120

TTTTTAATTC GACCGCACAC ATTATCAGTC CATTCCTACA GATCACCTGC TTTTTGTGAT 180

TATTGTGGTG AAATGCTTTG GGGGATTGTA AGGCAGGGCC TGCGTTGCGA TGGTTGCGGT 240

CAAAACTACC ACAAACGATG CGCATACAAA ATTCCGAATG ACTGCACTTT GGTGCGCAAA 300

CGAAAGGCTT CTGTATCGGC ATCTGTAAAT ACGTGGAATG GTTCCACTCT TTCCCTGCAA 360

GACTCAGTTT CATCGTCGGT AAGTGTGCAC TCTTACACAC GCCCTACAGT TTGCATGCAG 420

TGTAAAAAAC TGCTGAGAGG CTTCTTCAAA CAGGGAGTTC AGTGCAAAGG CATGTCCTAT 480

CTAACACTAC CCCGCAAAAC ACCACGTTCA TTAAGGGCAA TACATTACGT CTTAAAACAC 540

GCCCTTCAGG CACATTCATA TTGTGGACCA GCATCTCTTT ACATTTCCAG CTCGGACGCC 600

CCGAACATTC CCCTCATGCG TGTTGTGCAG TCGATAAAAC AAACCAAGAA GCGTTCGAGC 660

ACTGTGCTCA AAGAAGGCTG GCTGATTCAC TTCACAAACA AGGACTCAGT GAGGAGGCGA 720

CATTATTGGA GACTTGACTC GAAATCCATC ACGTTGTACA GATCTGAGAC TGGAGCGAAT 780

TATTTCAAGG AAATTGAACT GAGTGACATT CTAAGCATTC TGATGGTCAC CCGACTTCTT 840

CCTGGCGAGC CCTTGCACTT CTTTAAAATT TTAACCTCGG GCTTGGAACT TCTTGTGAGC 900

GATGATTCCG GCGAAATATA TTTGTTGCTG CGCAGACTAT GGACAATGAA CATCGACAAC 960

CACATGAACA TACACAGGTC GGAAAATGTG GTGGACTGGC ACACTCAGGT CTACCAAGCG 1020

TTGACTCCTG TAGATAGGAA GCAGGACTCC ACCAGCGGAA TTTACCAAGT GTTCCCGGAC 1080

GAAGTTCTCG GCTCGGGGCA GTTTGGTACA GTGTACGGGG GGAAGCACCG AAAGCGAGGC 1140

TTTGACGTAG CTATCAAGGT GGTGGACAAA CTTCGCTTCC AACACAAGGA GGAAAGTCAA 1200

CTTCGACACG AAGTGCAGAT CTTAGAGTGG TTAGACCATC CCGGCATAGT CAAGTTGTTC 1260

AATATGTTCG AGACGCCGGA GCAAGTGTTC GTTGTTATGG AGAAACTACG CGGTGATATG 1320

CTCGAAATGA TTTTGTCCAG CGAGAAAGGG CGGCTGCCGG AACGCATCAC GAAGTTCCTA 1380

ATCTCACAAA TTCTTATTGC ACTTCGCTAC TTGCACAAGC AAAATATCGT GCACTGCGAT 1440

CTCAAGCCGG AAAACGTTCT TCTCTCGAGC GACGACGCAT TCCCGCAGTT AAAACTGTGC 1500

GATTTCGGTT TCGCGAGGAT TATCGGGCAG AAGTCGTTCC GCAGATCGGT AGTCGGGACA 1560

CCTGCTTACC TGGCGCCTGA AGTGCTGCGG AAGGAGTGTT ACAACCGATC ACTTGACATG 1620

TGGTCGGTTG GCGTGATCAT CTACGTCAGC TTGTCGGGGA CTTTCCCGTT CAATGAAGAC 1680

GAGGATATCA ACCAGCAAAT ACAAAACGCT GCTTTCATGT ACCCGGCCCA CCCATGGAGT 1740

GGAATCAGTC ACGATTCTGT TGATCTCATC GGTTCCTTAC TCCAAGTTAA AAAGCGTAAA 1800

CGACCGTCGG TGGACAAAGC GCTCAGTCAT ATATGGCTTC AGGATTACCA GTGCTGGCAG 1860

GATCTCAGGC AGCTCGAACA GGTGGTTGGC AAACGGTATC TGACGCACGA AAGCGATGAC 1920

GACCGTTGGA GTGCGTACCA GAGGGAA 1947

Domain Profile

S: 1     ifadevlgsgqfgvvyggkhrktgrdvavkvidklrfptkqesqlrnevailqklkhpgv  60

         +f+devlgsgqfg+vyggkhrk g dva+kv+dklrf +k+esqlr ev+il+ l+hpg+

Q: 357   VFPDEVLGSGQFGTVYGGKHRKRGFDVAIKVVDKLRFQHKEESQLRHEVQILEWLDHPGI  416

         79**********************************************************

S: 61    vnlelmletkervfvvmeklkgdmlemilssekgrlseritkflitqilvalrylhfkni  120

         v+l  m+et+e+vfvvmekl+gdmlemilssekgrl+eritkfli+qil+alrylh++ni

Q: 417   VKLFNMFETPEQVFVVMEKLRGDMLEMILSSEKGRLPERITKFLISQILIALRYLHKQNI  476

         ************************************************************

S: 121   vhcdlkpenvllasadefpqvklcdfgfariigeksfrrsvvgtpaylapevlrnkgynr  180

         vhcdlkpenvll+s+d fpq klcdfgfariig+ksfrrsvvgtpaylapevlr++ ynr

Q: 477   VHCDLKPENVLLSSDDAFPQLKLCDFGFARIIGQKSFRRSVVGTPAYLAPEVLRKECYNR  536

         ************************************************************

S: 181   sldmwsvgviiyvslsgtfpfnededindqiqnaafmypaepwkeiseeaidlinnllqv  240

         sldmwsvgviiyvslsgtfpfnededin+qiqnaafmypa+pw+ is++++dli +llqv

Q: 537   SLDMWSVGVIIYVSLSGTFPFNEDEDINQQIQNAAFMYPAHPWSGISHDSVDLIGSLLQV  596

         ************************************************************

S: 241   klrkrysvdkslshawl  257

         k rkr svdk+lsh+wl

Q: 597   KKRKRPSVDKALSHIWL  613

         ****************8

Domain Sequence
(FASTA)

VFPDEVLGSG QFGTVYGGKH RKRGFDVAIK VVDKLRFQHK EESQLRHEVQ ILEWLDHPGI 60

VKLFNMFETP EQVFVVMEKL RGDMLEMILS SEKGRLPERI TKFLISQILI ALRYLHKQNI 120

VHCDLKPENV LLSSDDAFPQ LKLCDFGFAR IIGQKSFRRS VVGTPAYLAP EVLRKECYNR 180

SLDMWSVGVI IYVSLSGTFP FNEDEDINQQ IQNAAFMYPA HPWSGISHDS VDLIGSLLQV 240

KKRKRPSVDK ALSHIWL 257

Keyword

ATP-binding; Complete proteome; Kinase; Metal-binding; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase; Zinc; Zinc-finger.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005622	; C:intracellular
GO:0005524	; F:ATP binding
GO:0046872	; F:metal ion binding
GO:0005543	; F:phospholipid binding
GO:0004697	; F:protein kinase C activity
GO:0035556	; P:intracellular signal transduction

KEGG

InterPros

IPR020454	; DAG/PE-bd.
IPR011009	; Kinase-like_dom.
IPR011993	; PH_like_dom.
IPR001849	; Pleckstrin_homology.
IPR002219	; Prot_Kinase_C-like_PE/DAG-bd.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR015727	; Protein_Kinase_C_mu-related.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00130	; C1_1; 2.
PF00069	; Pkinase; 1.

SMARTs

SM00109	; C1; 2.
SM00233	; PH; 1.
SM00220	; S_TKc; 1.

Prosites

PS50003	; PH_DOMAIN; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.
PS00479	; ZF_DAG_PE_1; 1.
PS50081	; ZF_DAG_PE_2; 2.

Prints

PR00008

; DAGPEDOMAIN.

Created Date

20-Feb-2013