EKS-CIS-00047

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CIS-00047

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	358.8	2.0E-107	211	499	289

Status

Unreviewed

Ensembl Protein

ENSCSAVP00000016642

UniProt Accession

H2ZGC6;

Protein Name

Protein Synonyms/Alias

Gene Name

Csa.9355

Gene Synonyms/Alias

Csa.9355;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCSAVG00000009777	ENSCSAVP00000016642	ENSCSAVT00000016823

Organism

Ciona savignyi

Functional Description

Protein Length

594

Protein Sequence
(FASTA)

MWLYIVAGYL LTGVASQHLM CEYYYDNHEI QPVNERVCSD SEIDENGSCN TTQRCETGKD 60

LPGNRINCFV SWKNESGRIQ VLRKGCWTQT KPCTQRCDAL LKKSILFCCC DQDYCNSQFF 120

MHPNIKEPED TEGPVIKLSS DENQIWTVLA YTLVPITLLS VLVVFIYWCY RKRKHTYSNI 180

EIASVQTPGS ALNATAQHPN FMMQPEIKLP QLIDIKARGR FGCVWKAQLQ DKFVAVKVFY 240

VQDRQSWLNE QEVFNTELVH YHPNILNFIA AASRGVAVEA ELWLITEFHE LGSLADYLKT 300

NTMSLPVALK FMETMATGLS FLHEDIPHRE PHKGYKPAIA HRDFKSKNVL IRTDMTAVIA 360

DFGLAVKFVP GECAGENHGQ VGTRRYMAPE ILEGAINFQR DAFLRIDMYA FALVMWEIIT 420

RCSDSPGGAT PTYLMPYELE LGQHPTLDEM QALVIDQKSR PVVKDSWRQH EVIGILCETM 480

EDCWDHDAEA RSAGCVEERI NHLHRRVLAP NELPMHPNML NMDIIHNGSP LIGNGVIIPT 540

NDTDLQNQIN NQKNQEIPTA QEKVTNETSN TPAVVAVCDA ETALLTAGDR ESNV 594

Nucleotide Sequence
(FASTA)

ATGTGGCTGT ATATTGTTGC TGGCTATTTG CTTACTGGAG TTGCATCCCA ACATTTGATG 60

TGTGAATATT ACTACGACAA TCATGAAATA CAGCCAGTTA ACGAGCGGGT CTGCAGTGAT 120

TCTGAAATAG ATGAGAACGG ATCGTGCAAC ACTACACAAC GATGTGAGAC GGGTAAGGAC 180

TTACCTGGCA ATCGGATAAA CTGCTTTGTT AGTTGGAAGA ATGAATCCGG AAGAATACAA 240

GTATTAAGAA AGGGTTGTTG GACCCAGACT AAACCTTGCA CTCAAAGGTG TGATGCATTA 300

CTGAAGAAAT CAATATTGTT TTGTTGCTGT GACCAGGATT ACTGCAATTC ACAGTTTTTC 360

ATGCACCCCA ATATTAAAGA ACCAGAAGAC ACAGAGGGGC CAGTAATCAA GCTATCCAGT 420

GATGAGAACC AGATTTGGAC GGTGTTGGCG TATACGCTTG TTCCTATCAC TCTGCTCAGT 480

GTGCTTGTGG TCTTCATCTA CTGGTGTTAC AGAAAAAGAA AGCATACTTA CTCCAATATA 540

GAAATAGCAA GTGTGCAAAC ACCAGGATCA GCATTAAACG CAACTGCTCA ACACCCAAAC 600

TTCATGATGC AGCCCGAAAT CAAGCTGCCC CAGTTGATTG ATATTAAAGC AAGAGGAAGG 660

TTTGGCTGCG TGTGGAAAGC GCAACTACAG GATAAGTTTG TTGCAGTCAA AGTCTTCTAT 720

GTGCAGGACC GACAATCATG GCTCAATGAG CAGGAAGTAT TCAACACTGA GCTCGTGCAC 780

TACCATCCCA ACATACTCAA CTTCATAGCA GCTGCGAGTC GTGGAGTTGC TGTGGAAGCT 840

GAGTTATGGC TCATCACAGA GTTCCATGAG CTGGGATCTC TGGCAGATTA TCTGAAGACC 900

AACACCATGT CTCTTCCCGT TGCACTGAAG TTTATGGAAA CCATGGCAAC TGGACTATCC 960

TTCCTGCACG AGGACATACC ACACAGGGAG CCGCACAAAG GATATAAACC AGCAATCGCA 1020

CACCGAGATT TCAAGAGTAA GAATGTGCTT ATTAGAACTG ACATGACTGC TGTCATTGCT 1080

GATTTCGGCC TCGCGGTTAA GTTTGTCCCA GGGGAATGTG CCGGTGAAAA CCATGGCCAG 1140

GTTGGAACTC GGCGGTATAT GGCACCCGAA ATTTTAGAAG GAGCGATTAA CTTCCAGAGA 1200

GATGCTTTCT TGCGTATTGA CATGTACGCA TTCGCTCTTG TCATGTGGGA AATTATAACG 1260

AGATGCTCTG ATTCGCCAGG TGGTGCCACT CCCACATATC TTATGCCTTA CGAACTGGAG 1320

CTTGGCCAAC ACCCCACACT CGATGAAATG CAAGCGTTGG TTATTGACCA GAAATCAAGG 1380

CCTGTTGTTA AAGATAGCTG GAGACAGCAC GAGGTGATTG GTATCTTGTG CGAAACGATG 1440

GAGGATTGCT GGGATCATGA TGCGGAGGCG AGATCAGCCG GTTGTGTGGA GGAACGGATC 1500

AATCATCTGC ATCGCAGAGT TCTTGCACCG AATGAGCTCC CCATGCATCC CAACATGCTC 1560

AACATGGATA TCATTCACAA CGGGAGTCCA CTCATCGGCA ACGGGGTTAT CATCCCAACA 1620

AATGATACAG ACCTGCAGAA CCAGATAAAC AACCAAAAGA ACCAGGAGAT TCCTACTGCC 1680

CAAGAAAAAG TGACCAACGA AACAAGCAAT ACACCTGCGG TTGTGGCAGT GTGTGATGCA 1740

GAGACAGCCT TACTTACCGC TGGTGACCGA GAATCAAATG TCTGA 1785

Domain Profile

S: 2     klleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllr.henilqfia  60

         +l+++ ++Gr+g+Vwka+l+++ vAvK+f+ +d++sw +E+e+++t l++ h+nil+fia

Q: 211   QLIDIKARGRFGCVWKAQLQDKFVAVKVFYVQDRQSWLNEQEVFNTELVHyHPNILNFIA  270

         578999****************************************998769********

S: 61    adkkeedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtk  120

         a ++   ++ el+l+te+he gsL dyLk++t+++  +l++++++a+Gl++LHe+i+  +

Q: 271   AASRGVAVEAELWLITEFHELGSLADYLKTNTMSLPVALKFMETMATGLSFLHEDIPHRE  330

         ********************************************************7654

S: 121   g..kkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekeeldlaansqvGtkRYma  178

             +KpaiaHRD+kskN+l+++d+t++iaD+GLa+k+   + + +  ++ qvGt+RYma

Q: 331   PhkGYKPAIAHRDFKSKNVLIRTDMTAVIADFGLAVKFVPGECAGE--NHGQVGTRRYMA  388

         32479***********************************998665..8***********

S: 179   PEvleealnlkdfeafkraDvYslgLvlWEvasRcee.vdeeveeyklpfeevvgsdPsl  237

         PE+le+a+n+++ +af r+D+Y+++Lv+WE+++Rc++ ++++++ y +p+e ++g++P+l

Q: 389   PEILEGAINFQR-DAFLRIDMYAFALVMWEIITRCSDsPGGATPTYLMPYELELGQHPTL  447

         ***********9.9***********************99*********************

S: 238   eemkevvvekklrPkipeawkkkealkelsklleecWdadpeaRltalrvkkr  290

         +em+++v+++k rP ++++w+++e++  l++++e+cWd+d+eaR +a +v++r

Q: 448   DEMQALVIDQKSRPVVKDSWRQHEVIGILCETMEDCWDHDAEAR-SAGCVEER  499

         *******************************************9.67899987

Domain Sequence
(FASTA)

QLIDIKARGR FGCVWKAQLQ DKFVAVKVFY VQDRQSWLNE QEVFNTELVH YHPNILNFIA 60

AASRGVAVEA ELWLITEFHE LGSLADYLKT NTMSLPVALK FMETMATGLS FLHEDIPHRE 120

PHKGYKPAIA HRDFKSKNVL IRTDMTAVIA DFGLAVKFVP GECAGENHGQ VGTRRYMAPE 180

ILEGAINFQR DAFLRIDMYA FALVMWEIIT RCSDSPGGAT PTYLMPYELE LGQHPTLDEM 240

QALVIDQKSR PVVKDSWRQH EVIGILCETM EDCWDHDAEA RSAGCVEER 289

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0017002	; F:activin-activated receptor activity
GO:0005524	; F:ATP binding
GO:0004702	; F:receptor signaling protein serine/threonine kinase activity
GO:0005024	; F:transforming growth factor beta-activated receptor activity
GO:0023014	; P:signal transduction by phosphorylation

KEGG

InterPros

IPR000333	; Activin_II/TGFBeta-II_recpt.
IPR015768	; Activin_II_recpt.
IPR000472	; Activin_rcpt.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF01064	; Activin_recp; 1.
PF00069	; Pkinase; 1.

SMARTs

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR00653

; ACTIVIN2R.

Created Date

20-Feb-2013