EKS-CIS-00050

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CIS-00050

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/IRE	375.9	1.1E-112	536	793	258

Status

Unreviewed

Ensembl Protein

ENSCSAVP00000017790

UniProt Accession

H2ZJM4;

Protein Name

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSCSAVG00000010472	ENSCSAVP00000017790	ENSCSAVT00000017984
ENSCSAVG00000010472	ENSCSAVP00000017789	ENSCSAVT00000017983

Organism

Ciona savignyi

Functional Description

Protein Length

926

Protein Sequence
(FASTA)

EPLLLISTLD GTLHAVSKRT GLVKWKIDEN PVLTVPSEST TTIKGPTFLP DPHDGSLYAF 60

DPASQGLTKL PFTIPELVQA SPCRSSDGIL YTGRKQDVWY AINPLNGEKQ QVITTESATK 120

CPGGSTNHMF IGRSEYKVTM FDTKLNIMRW NVTFTDYSSH ANEKVSDSYE LLHLASSADG 180

FVITVDRRTA RILWAQNYGY PVVAMYAWVP EGLQRVEMTS VAKETMTYLM QQANGKVMSW 240

DSIFQGNPHF SPKEETLSPS LYVGQYRQSL YALPAMTHEG VQFDVSCFSV SILQILIQHN 300

LIFHPRRCTG MCSCYQDLMM KLKHQPNLTF QARIFQFGDC YHKIPPYSKV TLPRAYNPNT 360

KPPLQLEHKS HLKPLVEQVN ENYYPLFCVK RKKVGKSAFC FCSVASVVFL PILRDLRCIL 420

LCSKLVTFTL EKCLFRSRKW SRRCTTASFK AQFASYLCFH SREESENKAK KRDGGGKVES 480

DSNIRWNEIT IVATLTSVLT GALFLCLFKK PNFNFTNMAL GNKQGLVTVG RISVDPVDIL 540

GRGSEGTIVY KGHFDGRAVA VKRVVPECFS FADREVALLR ESDEHAHVIR YFCMERDTQF 600

QYIALEICSN TLQEYVENPQ YKCGTGLEPR TVLHQAMMGL DHLHQLKIVH RDVKPSNILI 660

SVPGKLGKQR VVISDFGLCK KLVPGRVSFS HRSGSAGTDG WIAPEIDSDK RYRMTQAVDI 720

FSMGCVFYYV ISGKHPFGDP ITRQARIING DYSLTELLSF ESAEEAIDLI KRMLLTDPVL 780

RPKSSTILKH PLFWDSVKTL QFFEDVSDRI EKEPPDSATM QQLDRDCLND IRNGIPRDWI 840

YHLCQPLQED LHKFRSYKAG SVRDLLRAIR NKKHHYRELP EEVKRSLGTV PDEFLTYFTS 900

RFPRLLTHTY LSMACCRHEP TFEHYY 926

Nucleotide Sequence
(FASTA)

GAACCCTTGC TGTTGATATC CACCTTGGAT GGGACGCTGC ATGCTGTTAG TAAACGTACC 60

GGACTTGTGA AATGGAAAAT AGATGAAAAT CCAGTGTTGA CTGTACCAAG TGAATCCACA 120

ACCACAATAA AAGGACCCAC CTTTCTACCT GACCCACATG ATGGTTCACT TTATGCATTT 180

GACCCAGCAT CACAAGGATT GACAAAACTT CCATTTACAA TACCGGAGCT GGTTCAAGCA 240

TCACCATGCA GGTCTTCTGA TGGTATTTTG TACACAGGTC GGAAACAAGA CGTTTGGTAT 300

GCTATAAACC CTTTAAATGG GGAGAAACAA CAAGTGATTA CCACTGAAAG TGCAACTAAA 360

TGTCCTGGTG GCAGCACTAA CCACATGTTT ATAGGCAGAT CAGAATACAA AGTCACGATG 420

TTTGACACAA AGCTAAACAT AATGAGGTGG AATGTGACGT TCACCGATTA TTCTTCCCAC 480

GCAAACGAAA AAGTATCGGA TAGTTACGAA TTACTTCATC TCGCTTCAAG TGCTGATGGC 540

TTTGTTATTA CAGTGGATCG CCGAACAGCT CGGATACTGT GGGCCCAAAA TTATGGATAC 600

CCTGTAGTTG CCATGTATGC TTGGGTGCCG GAAGGTCTAC AGAGAGTTGA GATGACAAGT 660

GTTGCTAAGG AAACAATGAC ATATCTCATG CAGCAAGCCA ATGGGAAAGT GATGTCATGG 720

GACTCTATTT TTCAAGGAAA CCCTCATTTT TCCCCCAAAG AAGAAACCCT CTCGCCTTCA 780

CTGTATGTTG GCCAGTACCG CCAAAGTCTC TATGCTCTTC CTGCAATGAC ACATGAAGGA 840

GTGCAATTTG ATGTGAGTTG CTTTTCTGTT TCTATTTTAC AAATTTTAAT TCAGCATAAT 900

TTAATTTTCC ATCCTCGCAG ATGCACAGGA ATGTGCAGTT GCTACCAGGA CCTAATGATG 960

AAGTTGAAAC ATCAACCGAA CTTGACATTC CAAGCTCGAA TATTCCAATT TGGAGACTGT 1020

TACCACAAAA TTCCCCCTTA CTCCAAGGTG ACCCTTCCAC GAGCTTACAA CCCCAACACG 1080

AAACCCCCAC TTCAGCTTGA ACATAAGTCT CATCTAAAAC CCCTTGTTGA GCAGGTAAAT 1140

GAAAATTATT ATCCGCTATT TTGCGTTAAA CGCAAAAAGG TTGGTAAAAG TGCATTTTGT 1200

TTTTGCTCTG TCGCCTCTGT TGTTTTTTTA CCAATACTAA GAGATTTACG CTGTATACTG 1260

CTATGTAGCA AGTTAGTAAC CTTCACTCTG GAAAAATGTC TATTTCGTAG CAGAAAATGG 1320

AGTAGAAGAT GCACAACAGC ATCTTTTAAA GCACAATTTG CATCATATCT TTGTTTCCAT 1380

TCTAGAGAAG AATCTGAGAA CAAAGCCAAA AAACGGGATG GTGGAGGAAA GGTTGAATCA 1440

GACTCAAACA TCCGTTGGAA CGAGATTACA ATTGTTGCAA CTCTCACATC TGTATTAACT 1500

GGCGCTCTAT TTCTGTGTTT GTTTAAGAAA CCCAACTTCA ACTTTACCAA CATGGCGCTG 1560

GGAAACAAGC AAGGACTGGT GACGGTCGGC AGGATATCTG TGGATCCTGT TGATATTCTT 1620

GGCAGAGGAA GTGAAGGCAC CATTGTGTAC AAGGGTCACT TTGACGGACG AGCAGTTGCA 1680

GTCAAAAGAG TAGTTCCTGA ATGCTTTAGT TTCGCGGATC GTGAGGTGGC TTTATTGAGG 1740

GAATCCGACG AACATGCTCA TGTCATCCGA TACTTCTGCA TGGAAAGAGA CACTCAGTTC 1800

CAATACATAG CACTCGAAAT ATGCAGCAAT ACATTGCAAG AGTATGTGGA AAATCCCCAA 1860

TATAAGTGCG GAACAGGATT GGAACCTAGA ACTGTTCTTC ACCAAGCAAT GATGGGTTTA 1920

GATCATTTGC ATCAACTTAA AATAGTGCAC CGTGATGTAA AACCGAGCAA TATATTGATA 1980

TCGGTGCCCG GCAAACTGGG CAAACAGCGC GTGGTCATCT CAGATTTCGG ACTTTGTAAG 2040

AAGCTCGTTC CGGGACGTGT TTCGTTCTCC CATCGATCCG GGAGTGCAGG CACAGATGGA 2100

TGGATCGCAC CGGAGATTGA TTCTGATAAA CGATATCGGA TGACCCAAGC GGTTGACATA 2160

TTTTCAATGG GCTGTGTGTT TTACTATGTG ATAAGTGGGA AGCATCCATT TGGGGACCCG 2220

ATCACAAGAC AAGCGAGAAT CATCAATGGA GACTACAGCC TCACAGAGTT ACTGTCATTT 2280

GAAAGTGCTG AAGAAGCAAT TGATTTAATA AAGCGAATGC TTCTAACTGA TCCAGTTCTG 2340

AGGCCAAAGT CAAGCACTAT TCTAAAACAC CCATTGTTCT GGGATTCTGT AAAGACTCTG 2400

CAATTTTTTG AGGACGTTAG CGATCGAATT GAAAAAGAGC CCCCCGATAG CGCCACCATG 2460

CAGCAGTTAG ATAGGGACTG TTTAAATGAT ATTCGTAACG GAATTCCTCG TGATTGGATC 2520

TATCACCTTT GCCAACCACT TCAGGAAGAT TTACACAAAT TCCGATCTTA CAAAGCTGGT 2580

TCTGTCCGGG ATTTATTACG GGCTATAAGG AACAAAAAGC ATCACTACCG AGAGCTTCCT 2640

GAAGAAGTGA AGAGGTCGTT GGGTACAGTA CCCGATGAAT TTCTCACCTA CTTCACTTCA 2700

CGTTTCCCAC GACTGCTTAC TCACACTTAT CTATCTATGG CCTGCTGTCG CCATGAACCA 2760

ACTTTTGAAC ACTATTAT 2778

Domain Profile

S: 3     pkdvlGkGaeGtvvfrGsfegrevavkrllsefvdlakrevkllresdehpnviryfcte  62

         p d+lG+G+eGt+v++G+f+gr+vavkr+++e++++a+rev+llresdeh +viryfc+e

Q: 536   PVDILGRGSEGTIVYKGHFDGRAVAVKRVVPECFSFADREVALLRESDEHAHVIRYFCME  595

         679*********************************************************

S: 63    kdrqfryialelcaaslqdyvedkdlelqkelepisllkqiasGlahlhslkivhrdlkp  122

         +d+qf+yiale+c+ +lq+yve+++ +  ++lep+++l+q++ Gl hlh lkivhrd+kp

Q: 596   RDTQFQYIALEICSNTLQEYVENPQYKCGTGLEPRTVLHQAMMGLDHLHQLKIVHRDVKP  655

         ************************************************************

S: 123   qnilislpdakgklrvlisdfGlckkldvGkssfsrrsgvsGteGwiapelleeltkerl  182

         +nilis+p + gk rv+isdfGlckkl  G+ sfs+rsg +Gt+Gwiape+ + + + r+

Q: 656   SNILISVPGKLGKQRVVISDFGLCKKLVPGRVSFSHRSGSAGTDGWIAPEIDS-DKRYRM  714

         **************************************************988.8899**

S: 183   tsavdifslGcvfyyvlskGkhpfGdslkrqanilsgelsldklkeekdeeviaedlisk  242

         t+avdifs+Gcvfyyv+s GkhpfGd ++rqa i++g++sl +l + +  e  a dli++

Q: 715   TQAVDIFSMGCVFYYVIS-GKHPFGDPITRQARIINGDYSLTELLSFESAE-EAIDLIKR  772

         *****************8.9**********************998877766.699*****

S: 243   midkdplkrpsakkvlkhplf  263

         m+ +dp  rp ++++lkhplf

Q: 773   MLLTDPVLRPKSSTILKHPLF  793

         ********************9

Domain Sequence
(FASTA)

PVDILGRGSE GTIVYKGHFD GRAVAVKRVV PECFSFADRE VALLRESDEH AHVIRYFCME 60

RDTQFQYIAL EICSNTLQEY VENPQYKCGT GLEPRTVLHQ AMMGLDHLHQ LKIVHRDVKP 120

SNILISVPGK LGKQRVVISD FGLCKKLVPG RVSFSHRSGS AGTDGWIAPE IDSDKRYRMT 180

QAVDIFSMGC VFYYVISGKH PFGDPITRQA RIINGDYSLT ELLSFESAEE AIDLIKRMLL 240

TDPVLRPKSS TILKHPLF 258

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0016891	; F:endoribonuclease activity, producing 5'-phosphomonoesters
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006397	; P:mRNA processing

KEGG

InterPros

IPR010513	; KEN_RNase_activator.
IPR011009	; Kinase-like_dom.
IPR018391	; PQQ_beta_propeller_repeat.
IPR000719	; Prot_kinase_cat_dom.
IPR006567	; PUG-dom.
IPR011047	; Quinonprotein_ADH-like.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF06479	; Ribonuc_2-5A; 1.

SMARTs

SM00564	; PQQ; 5.
SM00580	; PUG; 1.

Prosites

PS51392	; KEN; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013