EKS-DAR-00862

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DAR-00862

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CK1/CK1	456.8	3.8E-137	50	311	262

Status

Unreviewed

Ensembl Protein

ENSDARP00000056920

UniProt Accession

Q503C4; Q1LWK7;

Protein Name

Protein Synonyms/Alias

Casein kinase 1 gamma 2a; Casein kinase 1, gamma 2; Casein kinase 1, gamma 2a;

Gene Name

csnk1g2a

Gene Synonyms/Alias

csnk1g2a; csnk1g2; DKEY-218H11.5-001;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDARG00000005458	ENSDARP00000056920	ENSDART00000056921

Organism

Danio rerio

Functional Description

Protein Length

418

Protein Sequence
(FASTA)

MDFDKRGGGG GKGEAEDGKR MSKTGGSRTG HGGSRGSGNN TGVLMVGPNF RVGKKIGCGN 60

FGELRLGKNL YTNEYVAIKL EPIKSRAPQL HLEYRFYKQL GNAEGVPQVY YFGPCGKYNA 120

MVLELLGPSL EDLFDLCDRT FSLKTVLMIA IQLITRMEFV HTRSLIYRDV KPENFLVGRP 180

GTKRQHTIHI IDFGLAKEYI DPETKKHIPY REHKSLTGTA RYMSINTHLG KEQSRRDDLE 240

ALGHMFMYFL RGSLPWQGLK ADTLKERYQK IGDTKRATPI EVLCESFPEM ATYLRYVRRL 300

DFFERPDYEY LRKLFTDLFD RNGYVFDYEY DWVGKPLPTP IGPMPSDTPL QPSNRDKAQP 360

QTKNQVMSST NGEVNTDDPT AGHSNAPITA PAEVEVADDT KCCCFFKRRK RKALQRHK 418

Nucleotide Sequence
(FASTA)

ATGGATTTTG ATAAGAGAGG AGGAGGAGGA GGAAAAGGAG AAGCGGAGGA CGGAAAGAGA 60

ATGTCTAAGA CTGGCGGGAG CAGGACAGGG CATGGGGGCA GCCGAGGCTC CGGGAACAAC 120

ACTGGAGTGC TTATGGTTGG CCCGAATTTT CGGGTGGGAA AGAAGATTGG CTGCGGGAAC 180

TTCGGCGAGC TTCGACTCGG GAAGAATCTT TACACTAATG AATATGTGGC CATTAAACTG 240

GAGCCAATCA AATCAAGAGC ACCCCAACTC CATCTCGAAT ACAGGTTTTA CAAGCAGTTG 300

GGAAATGCAG AGGGTGTTCC TCAGGTCTAC TATTTCGGGC CTTGTGGGAA ATATAATGCC 360

ATGGTGCTGG AGCTGCTGGG ACCCAGTCTA GAGGACCTTT TTGACCTCTG CGACAGAACC 420

TTTTCACTTA AGACTGTCCT CATGATAGCC ATTCAGCTGA TCACACGGAT GGAGTTTGTG 480

CACACAAGAA GTCTGATCTA CAGGGATGTT AAGCCTGAAA ACTTCTTGGT GGGCCGACCG 540

GGGACCAAGA GGCAGCATAC AATCCACATC ATCGACTTTG GACTTGCCAA AGAATACATC 600

GACCCCGAGA CCAAAAAACA CATCCCTTAC AGGGAGCACA AGAGTTTAAC AGGGACGGCT 660

CGCTACATGA GCATCAACAC ACACCTGGGG AAGGAGCAAA GCAGGCGGGA TGATTTGGAG 720

GCGCTAGGTC ATATGTTTAT GTACTTCCTA CGAGGCAGTC TGCCTTGGCA AGGCTTGAAG 780

GCTGACACGT TGAAGGAGCG ATATCAGAAA ATCGGAGACA CCAAAAGGGC AACCCCTATA 840

GAAGTGCTCT GTGAGAGTTT CCCTGAAATG GCCACCTACC TACGCTACGT GCGGAGACTG 900

GATTTCTTTG AAAGACCGGA TTATGAATAC TTGAGAAAAC TCTTTACAGA CCTCTTCGAC 960

AGAAACGGCT ATGTTTTCGA CTATGAATAT GACTGGGTCG GCAAGCCACT GCCGACTCCA 1020

ATAGGACCCA TGCCTAGTGA CACACCACTG CAGCCCAGCA ACAGAGACAA AGCACAACCA 1080

CAGACCAAAA ACCAGGTTAT GAGCTCGACC AACGGAGAAG TAAATACAGA CGATCCCACA 1140

GCGGGACACT CCAACGCTCC CATAACTGCC CCAGCTGAGG TGGAGGTGGC CGATGATACA 1200

AAGTGCTGTT GTTTTTTCAA GAGGAGGAAG AGGAAAGCGC TCCAGCGGCA CAAGTGA 1257

Domain Profile

S: 1     yrvvkkiGsGsfGdiylgknlasgeevaikleskkskapqlklesrvykilqggvgiPev  60

         +rv+kkiG+G+fG+++lgknl+++e+vaikle++ks+apql+le+r+yk+l +++g+P+v

Q: 50    FRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGNAEGVPQV  109

         89**********************************************************

S: 61    ryfgkekkynvlvldllGpsledlfdlcerkfslktvllladqlisrieyvhskeliyrd  120

         +yfg+++kyn++vl+llGpsledlfdlc+r+fslktvl++a+qli+r+e+vh+++liyrd

Q: 110   YYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLITRMEFVHTRSLIYRD  169

         ************************************************************

S: 121   ikPdnfllgigrkgkk....vylidfGlakkyrdaktkkhipyreeksltGtaryasint  176

         +kP+nfl+g  r g+k    +++idfGlak+y+d++tkkhipyre+ksltGtary+sint

Q: 170   VKPENFLVG--RPGTKrqhtIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINT  227

         *******65..444444455****************************************

S: 177   hlgkeqsrrddleslgyvllyflrgslPWqglkaatkkqkyekisekklstsievlcegf  236

         hlgkeqsrrddle+lg++++yflrgslPWqglka+t k++y+ki+++k++t+ievlce+f

Q: 228   HLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCESF  287

         ************************************************************

S: 237   PeefatylkyvrklkfeekPdyeyl  261

         P e+atyl+yvr+l+f+e+Pdyeyl

Q: 288   P-EMATYLRYVRRLDFFERPDYEYL  311

         *.8********************97

Domain Sequence
(FASTA)

FRVGKKIGCG NFGELRLGKN LYTNEYVAIK LEPIKSRAPQ LHLEYRFYKQ LGNAEGVPQV 60

YYFGPCGKYN AMVLELLGPS LEDLFDLCDR TFSLKTVLMI AIQLITRMEF VHTRSLIYRD 120

VKPENFLVGR PGTKRQHTIH IIDFGLAKEY IDPETKKHIP YREHKSLTGT ARYMSINTHL 180

GKEQSRRDDL EALGHMFMYF LRGSLPWQGL KADTLKERYQ KIGDTKRATP IEVLCESFPE 240

MATYLRYVRR LDFFERPDYE YL 262

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Dasypus novemcinctus"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

dre:554152

;

InterPros

IPR022247	; Casein_kinase-1_gamma_C.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF12605	; CK1gamma_C; 1.
PF00069	; Pkinase; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013