EPS-DAR-00060

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-DAR-00060

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	176.3	2.0E-51	143	394	252

Status

Unreviewed

Ensembl Protein

ENSDARP00000051665

UniProt Accession

A2BE49;

Protein Name

Protein Synonyms/Alias

Novel protein similar to vertebrate protein phosphatase 1F (PP2C domain containing) (PPM1F);

Gene Name

ppm1f

Gene Synonyms/Alias

ppm1f; DKEY-72G15.2; DKEY-72G15.2-001;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDARG00000005786	ENSDARP00000051665	ENSDART00000051666

Organism

Danio rerio

Functional Description

Protein Length

424

Protein Sequence
(FASTA)

MSGAEKGDVR TFLESFLQEF SKPLGTEDPL PVSSANRIIS LQELKGESLD LGLRLLSARN 60

APSWLAAVMC NVAVTELLKD DLTPHYCPKD PEQQPEDEQG VVLLQSEPVL RLFINKLRAV 120

GVAWQKQPPN PDAPSSRTHS CSVHAIRNTR RKMEDRHVIL KEFNQLLGLQ DGVGREYYAV 180

FDGHGGVDAA TYSATHLHIV LSQQGELKTD AATAFKNTFT QTDDMFKIKA KRERLRSGST 240

GVAVLLTSDL LTVSWLGDSQ ALLVRQGEPV TLMDPHKPER EDEKKRIEDL GGCIAFMGCW 300

RVNGTYAVSR AIGDFDQKPY VSNEADSSSF HLTGDEDYVL LACDGFFDVI RPADVPALVL 360

EALRESGGSG NDVAQSLVAQ AKTAGSSDNI TVLLVFLKEP QKLLAHDTVC RTEGRGAACA 420

AAGV 424

Nucleotide Sequence
(FASTA)

ATGAGTGGCG CAGAAAAAGG AGATGTCAGG ACGTTTCTTG AGAGTTTTCT GCAAGAGTTT 60

TCGAAACCGC TCGGGACAGA AGATCCACTG CCAGTCAGTT CAGCGAACCG AATCATCTCT 120

CTGCAGGAGC TGAAGGGAGA AAGTCTGGAT TTAGGCCTCC GACTGCTTTC AGCCAGAAAT 180

GCTCCATCAT GGCTGGCTGC AGTGATGTGC AATGTTGCTG TCACTGAACT GCTCAAAGAT 240

GACCTTACAC CTCACTACTG CCCCAAAGAC CCCGAACAGC AACCAGAAGA TGAACAAGGA 300

GTTGTTTTGC TGCAGTCTGA ACCTGTGCTG CGTCTCTTCA TTAATAAATT GAGAGCGGTG 360

GGTGTGGCCT GGCAGAAACA GCCGCCCAAT CCCGATGCTC CCTCTTCGCG CACACACAGC 420

TGCTCAGTTC ACGCCATTCG AAACACCCGC AGGAAGATGG AGGATCGCCA CGTCATCTTA 480

AAAGAGTTTA ACCAGCTTCT GGGACTGCAG GATGGTGTGG GTAGAGAGTA TTATGCTGTG 540

TTTGATGGGC ATGGAGGAGT AGACGCTGCC ACTTACAGTG CCACTCATCT GCATATAGTA 600

CTGAGCCAGC AGGGGGAGCT AAAAACAGAC GCTGCCACAG CCTTTAAAAA CACCTTCACA 660

CAAACAGATG ACATGTTCAA GATCAAAGCC AAGAGAGAGC GTCTGCGCAG CGGCAGCACT 720

GGAGTGGCTG TTTTACTGAC CTCTGACCTC CTTACCGTGT CCTGGCTGGG CGATTCCCAA 780

GCTCTGCTGG TCCGCCAGGG GGAACCAGTG ACCCTAATGG ACCCCCACAA ACCAGAGCGA 840

GAGGATGAGA AGAAAAGGAT TGAGGATCTG GGTGGATGCA TCGCTTTCAT GGGTTGTTGG 900

CGGGTAAATG GTACCTACGC CGTTTCCAGA GCAATAGGTG ACTTTGACCA GAAGCCGTAC 960

GTCTCTAATG AAGCTGACAG CTCCTCTTTC CATCTGACCG GGGATGAAGA TTACGTCCTC 1020

CTGGCCTGTG ACGGCTTCTT CGACGTGATC CGGCCTGCAG ATGTCCCAGC TCTGGTACTG 1080

GAGGCTCTGC GGGAGAGCGG AGGTTCTGGA AACGATGTGG CCCAGAGTCT AGTGGCCCAG 1140

GCCAAAACTG CCGGATCCAG CGACAATATC ACTGTCCTCC TGGTGTTCCT GAAGGAGCCG 1200

CAGAAACTTC TGGCTCACGA CACCGTTTGC AGAACTGAGG GACGAGGAGC TGCATGTGCG 1260

GCCGCAGGGG TCTAA 1275

Domain Profile

S: 5     vvsvngrrnemedavtsspnflkspekkdr..laffgvyDGhggsevakfcseklheila  62

         v ++ + r++med++ + ++f +  + +d     +++v+DGhgg ++a + +++lh +l

Q: 143   VHAIRNTRRKMEDRHVILKEFNQLLGLQDGvgREYYAVFDGHGGVDAATYSATHLHIVLS  202

         678999*****************99998877779**************************

S: 63    eelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikdsklyvanv  122

         ++ e     +++  +a++++F++td  + ++++k  +  +sGst v +l++++ l+v+ +

Q: 203   QQGE----LKTDAATAFKNTFTQTDDMF-KIKAK-RERLRSGSTGVAVLLTSDLLTVSWL  256

         **55....7788888*************.44444.46667********************

S: 123   GdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlGvLavsRalGdly  182

         GdS+a+L r+g++v+l + Hkp+redE++Rie+ gg ++   + Rv+G  avsRa+Gd++

Q: 257   GDSQALLVRQGEPVTLMDPHKPEREDEKKRIEDLGGCIAFMGCWRVNGTYAVSRAIGDFD  316

         ***********************************999988656****************

S: 183   lkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvle.kkeaeqeaakk  241

          kpyv+ e + +s+ lt +++++ La+DG +dv+ + ++ +lv + l+ ++ + +++a++

Q: 317   QKPYVSNEADSSSFHLTGDEDYVLLACDGFFDVIRPADVPALVLEALReSGGSGNDVAQS  376

         ********************************************999868899*******

S: 242   Lvklalargskdnvsaiv  259

         Lv++a   gs+dn+++++

Q: 377   LVAQAKTAGSSDNITVLL  394

         **************8876

Domain Sequence
(FASTA)

VHAIRNTRRK MEDRHVILKE FNQLLGLQDG VGREYYAVFD GHGGVDAATY SATHLHIVLS 60

QQGELKTDAA TAFKNTFTQT DDMFKIKAKR ERLRSGSTGV AVLLTSDLLT VSWLGDSQAL 120

LVRQGEPVTL MDPHKPERED EKKRIEDLGG CIAFMGCWRV NGTYAVSRAI GDFDQKPYVS 180

NEADSSSFHL TGDEDYVLLA CDGFFDVIRP ADVPALVLEA LRESGGSGND VAQSLVAQAK 240

TAGSSDNITV LL 252

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>