EKS-DAR-00339

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DAR-00339

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/TOPK	437.2	5.4E-131	36	320	285

Status

Reviewed

Ensembl Protein

ENSDARP00000013651

UniProt Accession

Q6DHU8; Q5SPR6;

Protein Name

Lymphokine-activated killer T-cell-originated protein kinase homolog

Protein Synonyms/Alias

PDZ-binding kinase;

Gene Name

pbk

Gene Synonyms/Alias

pbk; topk; zgc:92050;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDARG00000007221	ENSDARP00000013651	ENSDART00000021788
ENSDARG00000007221	ENSDARP00000114079	ENSDART00000136476

Organism

Danio rerio

Functional Description

Protein Length

339

Protein Sequence
(FASTA)

MEASKESPSA FKTPCKPAKV KSPVNACGTP VTIPASPFMK KLGCGTGVNV YLMNRMGKQT 60

HSPWAIKKIN SKCAQGQVSV YQKRLCEEAK ILKDLKHPNI VGFRAFTTAK DGSKCLAMEF 120

GGEQSLNDLI EKRREEGLQA FPVDTIEKVA LHVARGLLYL HNEKKLLHGD MKSCNVVIKG 180

DFESIKICDV GVSLPLDENM QVSDPKAHYI GTEPWKPKEA LEDGVITDKA DIFAYGLTLW 240

EMMTLSVPHL EMLDTEGDED DDDESFEEDF DEDAYYERLG SRPALDAVTL GGSYQRMVEL 300

FCLCTEEDPQ KRPSAAHIVQ VLESNSQLSK QNTEVIVID 339

Nucleotide Sequence
(FASTA)

ATGGAGGCCA GCAAAGAATC ACCGAGTGCC TTTAAAACAC CTTGCAAGCC TGCTAAAGTG 60

AAAAGTCCAG TCAATGCTTG TGGGACCCCA GTCACCATTC CTGCCTCTCC CTTCATGAAG 120

AAGCTCGGCT GTGGGACTGG AGTCAATGTT TACCTCATGA ACAGGATGGG GAAACAGACT 180

CATTCTCCAT GGGCTATAAA GAAGATCAAC AGCAAGTGTG CTCAAGGTCA AGTGAGTGTT 240

TATCAGAAGC GTCTCTGTGA GGAGGCCAAG ATCTTGAAGG ACCTCAAGCA CCCCAATATT 300

GTTGGCTTCA GAGCTTTTAC CACTGCGAAG GATGGCTCGA AGTGTCTAGC GATGGAGTTT 360

GGCGGAGAAC AGTCTCTCAA TGACCTGATT GAGAAGAGGA GAGAGGAGGG TCTGCAGGCC 420

TTTCCAGTGG ACACTATTGA AAAAGTGGCT CTTCATGTCG CTCGCGGTTT ACTGTACTTG 480

CACAATGAGA AAAAGCTTCT GCATGGAGAC ATGAAATCAT GCAATGTTGT CATCAAGGGC 540

GATTTTGAGA GCATCAAAAT CTGTGATGTT GGTGTTTCAC TGCCACTGGA TGAAAACATG 600

CAAGTGAGTG ATCCAAAGGC TCATTACATT GGGACGGAGC CGTGGAAGCC CAAAGAAGCT 660

TTGGAGGATG GAGTAATCAC AGATAAAGCT GATATCTTTG CCTATGGACT CACACTGTGG 720

GAAATGATGA CGCTTTCTGT TCCTCACCTG GAGATGCTGG ACACTGAGGG TGATGAAGAT 780

GATGATGACG AGTCATTTGA GGAGGATTTT GATGAAGATG CATATTATGA GCGGCTGGGG 840

TCTCGACCGG CTCTGGACGC AGTGACTCTG GGAGGCTCTT ATCAGAGGAT GGTGGAGCTC 900

TTCTGTCTCT GCACAGAGGA GGACCCTCAG AAAAGACCCT CAGCAGCTCA CATTGTGCAG 960

GTGCTGGAGT CAAACAGCCA GCTTTCCAAG CAAAACACTG AGGTAATTGT AATCGATTAA 1020

Domain Profile

S: 1     splmkklGfGtGvrvyllkrsprGlsrspwavkkisqllddkkrtvyqkrlvdeakilkk  60

         sp+mkklG GtGv+vyl++r  + +++spwa+kki+  + + + +vyqkrl +eakilk+

Q: 36    SPFMKKLGCGTGVNVYLMNRMGK-QTHSPWAIKKINSKCAQGQVSVYQKRLCEEAKILKD  94

         8*******************987.68**********************************

S: 61    lkhpnivGyravieaddGsltlaleyggekslndlleernkesldplpaavilkvildva  120

         lkhpnivG+ra+++a+dGs++la+e+gge+slndl+e+r +e l+ +p  +i kv+l+va

Q: 95    LKHPNIVGFRAFTTAKDGSKCLAMEFGGEQSLNDLIEKRREEGLQAFPVDTIEKVALHVA  154

         ************************************************************

S: 121   ralkylhqekkllhGdlkssnvvikGdfeiiklcdvGvslpldenmevtdpearyiGtel  180

         r+l ylh+ekkllhGd+ks nvvikGdfe ik+cdvGvslpldenm+v+dp+a yiGte+

Q: 155   RGLLYLHNEKKLLHGDMKSCNVVIKGDFESIKICDVGVSLPLDENMQVSDPKAHYIGTEP  214

         ************************************************************

S: 181   wkakeaieendvitdkadifafGlvlyemlalviphvnlsd...ddldedaaldesdfdd  237

         wk+kea+e  +vitdkadifa+Gl+l+em++l++ph+++ d   d++d+d++++e dfd+

Q: 215   WKPKEALE-DGVITDKADIFAYGLTLWEMMTLSVPHLEMLDtegDEDDDDESFEE-DFDE  272

         *******6.69*************************9986533377888899999.****

S: 238   eayyaalgtrdklnmeeldesyqkvielfsvstdedkkdrpsaaeive  285

         +ayy+ lg+r+ l+   l  syq+++elf+++t+ed++ rpsaa+iv+

Q: 273   DAYYERLGSRPALDAVTLGGSYQRMVELFCLCTEEDPQKRPSAAHIVQ  320

         **********************************************97

Domain Sequence
(FASTA)

SPFMKKLGCG TGVNVYLMNR MGKQTHSPWA IKKINSKCAQ GQVSVYQKRL CEEAKILKDL 60

KHPNIVGFRA FTTAKDGSKC LAMEFGGEQS LNDLIEKRRE EGLQAFPVDT IEKVALHVAR 120

GLLYLHNEKK LLHGDMKSCN VVIKGDFESI KICDVGVSLP LDENMQVSDP KAHYIGTEPW 180

KPKEALEDGV ITDKADIFAY GLTLWEMMTL SVPHLEMLDT EGDEDDDDES FEEDFDEDAY 240

YERLGSRPAL DAVTLGGSYQ RMVELFCLCT EEDPQKRPSA AHIVQ 285

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Phosphoprotein; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>