EKS-DAR-00076

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DAR-00076

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	383.5	1.2E-114	135	416	282

Status

Unreviewed

Ensembl Protein

ENSDARP00000002635

UniProt Accession

E7F9R5;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC100150007

Gene Synonyms/Alias

LOC100150007;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDARG00000012204	ENSDARP00000002635	ENSDART00000005864

Organism

Danio rerio

Functional Description

Protein Length

465

Protein Sequence
(FASTA)

MNKMKNFKRR FSLSVPRTET IEENEFTEQI NQLNIRCNDG VVPNSLGLHS LQPSPVAPDS 60

QAQSPTQLQY RNKVQHRRFS MEDVTKRMSL PMDIRLPPEF LKKLQMESPP PCKPLSRMSR 120

RASLSDIGFG KLETYVKLGK LGEGTYATVF KGRSKLTENL VALKEIRLEH EEGAPCTAIR 180

EVSLLKNLKH ANIVTLHDII HTDRCLTLVF EYLDSDLKQY LDNCGNLMSM HNVKIFMFQL 240

LRGLSYCHKR KILHRDLKPQ NLLINDKGEL KLADFGLARA KSVPTKTYSN EVVTLWYRPP 300

DVLLGSTEYS TPIDMWGVGC ILYEMATGRP MFPGSTVKEE LHLIFRLMGT PTEESWPGIT 360

ANEEFKSYLF PQYRAQALIN HVPRLDTEGI DLLTALLLYD TKRRISAELS LRHSYFQTLG 420

ENILSIPDTS SVFSLREIQL QKDPGHRSSV FQPPGRGKNR RQSIF 465

Nucleotide Sequence
(FASTA)

ATGAACAAGA TGAAGAACTT TAAGAGGCGT TTCTCACTTT CTGTGCCACG AACAGAGACG 60

ATAGAGGAAA ACGAGTTTAC AGAGCAGATA AACCAGCTCA ACATCCGCTG CAATGATGGT 120

GTGGTGCCCA ACAGTCTGGG TCTACACAGC CTGCAACCCA GTCCAGTGGC TCCAGACAGC 180

CAGGCTCAAT CTCCAACCCA ACTACAGTAC CGCAACAAAG TCCAGCACCG CCGATTCTCC 240

ATGGAGGATG TAACTAAGAG GATGTCTCTG CCCATGGATA TTCGTCTCCC GCCAGAGTTT 300

CTGAAGAAGT TGCAGATGGA AAGCCCACCG CCGTGCAAAC CTCTGAGCCG CATGTCCAGA 360

AGAGCATCGC TGTCAGACAT TGGCTTTGGG AAACTGGAGA CTTATGTGAA GTTGGGCAAA 420

CTAGGAGAGG GCACATATGC CACCGTTTTC AAGGGTCGCA GCAAACTCAC AGAAAACCTA 480

GTGGCTCTGA AAGAGATTCG TCTGGAGCAT GAAGAGGGCG CCCCCTGCAC AGCCATACGG 540

GAAGTGTCAC TCCTGAAGAA CCTGAAACAC GCCAACATCG TAACGCTGCA TGACATCATC 600

CACACGGACC GATGCCTCAC TCTTGTATTT GAGTACCTGG ACAGTGACTT GAAGCAGTAC 660

CTCGACAACT GTGGAAACCT AATGAGCATG CACAACGTTA AGATATTTAT GTTCCAGCTC 720

CTTCGCGGTT TATCATATTG TCATAAGAGG AAGATTCTCC ACCGGGACCT GAAGCCTCAG 780

AATCTGCTCA TTAATGACAA GGGAGAACTC AAGCTGGCAG ACTTTGGTTT GGCCAGAGCG 840

AAATCGGTCC CGACAAAAAC CTATTCGAAC GAGGTGGTGA CCTTGTGGTA TCGACCCCCT 900

GATGTTCTGC TGGGATCCAC TGAATACTCC ACACCCATAG ACATGTGGGG TGTGGGGTGT 960

ATCCTGTATG AAATGGCGAC GGGGCGACCC ATGTTTCCTG GATCGACTGT CAAAGAGGAA 1020

CTACACCTGA TATTTCGGCT CATGGGCACC CCAACTGAGG AGAGCTGGCC TGGAATCACA 1080

GCTAATGAGG AATTCAAATC CTACCTGTTT CCTCAGTACC GAGCTCAAGC GCTCATTAAT 1140

CATGTGCCCA GGCTCGACAC GGAGGGGATA GACCTTCTCA CAGCACTGTT GCTGTACGAC 1200

ACAAAGCGCA GGATTTCAGC TGAACTGTCT CTGAGACACT CTTACTTCCA GACCCTAGGC 1260

GAGAACATCC TCTCCATACC TGACACCTCA TCCGTGTTTT CACTGAGGGA GATTCAGCTA 1320

CAGAAGGATC CGGGACATCG GAGTTCAGTA TTCCAGCCTC CGGGTCGAGG CAAGAACCGC 1380

AGACAAAGCA TATTCTGA 1398

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y kl k+geGty++v+k+++k t+++vAlK+irle+e eg p+ta+rE+sllk+lkh+ni

Q: 135   YVKLGKLGEGTYATVFKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKNLKHANI  193

         78999*******************************9.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v+L+++++ +++ l+Lvfe+l++dLk++l+++ +  +s+++vk +++qll+gl+y+H++k

Q: 194   VTLHDIIH-TDRCLTLVFEYLDSDLKQYLDNCGN-LMSMHNVKIFMFQLLRGLSYCHKRK  251

         ********.99***********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         ilHRDlKpqNlLi+++g+lklaDfGlara s+p+kty++evvTlwYr+P++Llg++eYst

Q: 252   ILHRDLKPQNLLINDKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYST  311

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ksfp  239

          +D+W+vgcil e++t +p+f+g++ +++l+ if+l+gtp+e++wp+++  +e+k + fp

Q: 312   PIDMWGVGCILYEMATGRPMFPGSTVKEELHLIFRLMGTPTEESWPGITANEEFKsYLFP  371

         *******************************************************899**

S: 240   kkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         +++++ l ++v++l+++++dll+ ll +d k+Risa+  l+h+yf

Q: 372   QYRAQALINHVPRLDTEGIDLLTALLLYDTKRRISAELSLRHSYF  416

         ********************************************9

Domain Sequence
(FASTA)

YVKLGKLGEG TYATVFKGRS KLTENLVALK EIRLEHEEGA PCTAIREVSL LKNLKHANIV 60

TLHDIIHTDR CLTLVFEYLD SDLKQYLDNC GNLMSMHNVK IFMFQLLRGL SYCHKRKILH 120

RDLKPQNLLI NDKGELKLAD FGLARAKSVP TKTYSNEVVT LWYRPPDVLL GSTEYSTPID 180

MWGVGCILYE MATGRPMFPG STVKEELHLI FRLMGTPTEE SWPGITANEE FKSYLFPQYR 240

AQALINHVPR LDTEGIDLLT ALLLYDTKRR ISAELSLRHS YF 282

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

dre:100150007

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013