EKS-DAR-00632

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DAR-00632

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/IRE	458.5	1.4E-137	572	833	262

Status

Unreviewed

Ensembl Protein

ENSDARP00000018218

UniProt Accession

F1QYL2;

Protein Name

Protein Synonyms/Alias

Gene Name

ern1

Gene Synonyms/Alias

ern1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDARG00000013997	ENSDARP00000018218	ENSDART00000014182

Organism

Danio rerio

Functional Description

Protein Length

1031

Protein Sequence
(FASTA)

MAWGVCSRAL VWIITALIWW SHSGLMGFCS SSTVSVPESL LFVSTLDGNL HAVSKISGTI 60

KWTLKEDPVL QVPTHVSEPA FLPDPNDGSL YSLGGKNNEG LTKLPFTIPE LVQASPCRSS 120

DGILYMGKKQ DVWYVVDLLT GEKKQTLTSS YAEMLCPSSS LFYLGRTEYT ITMYDTKSRE 180

LRWNATYSDY AFTLPDEDTK YNMAHFVSNG DGLVVTVDSE SGDVQWVQNY NSPVVAVYIW 240

QREGLRKVPH TNVAVETLRY LTFMSGEVGR ITQWKYPFPR EKKTKDKLLS TLYVGKHSSG 300

LYASPSLVHD GVTVVPRGRT FPMLEGPGNQ GSREEDEQEC VITPSTTVNF NAALKERNRI 360

NFMRNSLLLI GHHEMPPDAH HKFLEKFPES IPRQNMNVIP PATEKTIEEK VNESGMEDNS 420

PLPPPVSSLQ EKPGRVPRVE TPVDSMLKDM ATIIFCTFLL AGWVAFVITY PKSVHKQQQL 480

QHQQFQQQME EKLQLLQRQQ LIFQPPTDLP PDSDFLEAAR TRSESSTHSS PNGTPRASNH 540

SNISQCETGH SANEHEDTEE ESNIVRIGNI TFNPKNVLGH GAEGTIVYRG QFDNRPVAVK 600

RILPECFSFA DREVQLLRES DEHPNVIRYF CTERDRQFQY IAIELCNSTL QEYVERKDFN 660

RHGLEPVTLL EQTMSGLAHL HSLNIVHRDL KPHNILVSMP NMHGRVKAMI SDFGLCKKLA 720

VGRHSFSRKS GVPGTEGWIA PEVLSEDAKH NPTCMVDIFS AGCVFYYVVS EGFHPFGKSL 780

QRQANILLGA YSLDHLDPNR HESIVARNLI EQMLNMEPEK RPSADRVLKH PFFWSLEKQL 840

HFFQDVSDRI EKEPLDGPIV RQLERGGRVV VKGDWRDHIT VPLQTDLRKF RSYKGGSVRD 900

LLRAMRNKKH HYRELPEDVQ QTLGTIPDEF VFYFTSRFPL LLQHTHLAMR YCAVERSFLP 960

YYHVSELLAH HTIMQCVPQT SSTQHSCASE PSGLSSSSQI SESLHELPDA LSEMAAPSEH 1020

TQTGPEKTGA P 1031

Nucleotide Sequence
(FASTA)

ATGGCGTGGG GAGTGTGCAG CAGGGCTCTT GTGTGGATTA TAACTGCGTT GATATGGTGG 60

AGTCACAGTG GTCTGATGGG CTTCTGCAGC AGTAGTACAG TGTCTGTACC AGAAAGTCTG 120

CTCTTTGTGT CCACCTTAGA TGGGAACCTT CATGCTGTCA GCAAGATATC TGGAACCATC 180

AAATGGACCT TGAAAGAAGA TCCTGTTTTA CAAGTCCCGA CGCACGTGTC AGAGCCTGCA 240

TTTCTCCCGG ATCCCAATGA TGGCAGTTTG TACTCTCTCG GAGGGAAGAA TAATGAAGGG 300

TTGACGAAAC TGCCGTTTAC CATTCCTGAG CTGGTTCAGG CATCACCCTG TCGCAGTTCT 360

GATGGCATCT TATACATGGG TAAGAAGCAG GATGTGTGGT ATGTTGTGGA TCTGCTGACT 420

GGTGAAAAGA AGCAGACTCT GACTTCCTCC TATGCTGAGA TGTTATGTCC ATCTTCGTCC 480

CTGTTTTACC TTGGCCGCAC AGAATACACG ATCACTATGT ATGACACCAA AAGCAGAGAG 540

CTGCGCTGGA ATGCTACTTA CTCTGACTAT GCCTTCACCC TTCCAGATGA AGACACCAAA 600

TACAATATGG CCCACTTTGT GTCCAATGGC GATGGTCTAG TGGTGACAGT GGACAGCGAG 660

TCTGGAGACG TGCAGTGGGT TCAGAACTAC AACTCCCCTG TGGTGGCAGT CTATATCTGG 720

CAGCGTGAGG GACTGCGCAA AGTCCCACAC ACCAATGTTG CTGTTGAAAC ATTACGCTAC 780

CTCACGTTCA TGTCAGGAGA GGTGGGCCGC ATCACACAGT GGAAGTATCC ATTTCCTCGA 840

GAAAAGAAAA CCAAAGATAA ACTGTTGTCC ACTTTGTACG TGGGGAAACA CTCCTCTGGT 900

CTATATGCGT CTCCCTCCCT GGTGCATGAC GGAGTTACTG TTGTGCCTCG AGGCCGGACA 960

TTTCCCATGC TGGAGGGCCC CGGTAACCAG GGATCACGTG AGGAAGATGA ACAGGAGTGT 1020

GTTATCACTC CTAGCACCAC GGTGAATTTC AATGCAGCGC TCAAAGAGAG GAACCGCATC 1080

AATTTCATGA GGAATTCTCT GCTCCTGATC GGGCATCACG AGATGCCGCC TGATGCTCAC 1140

CATAAATTCT TGGAGAAGTT TCCAGAGAGC ATTCCCCGCC AGAACATGAA CGTTATTCCC 1200

CCTGCCACGG AAAAGACCAT TGAAGAGAAA GTGAATGAGA GCGGAATGGA AGACAACAGT 1260

CCACTGCCTC CCCCTGTGTC CTCTCTTCAG GAGAAGCCTG GCCGTGTCCC ACGAGTGGAA 1320

ACTCCAGTGG ACTCCATGCT GAAGGACATG GCCACCATCA TCTTCTGCAC TTTCCTTCTG 1380

GCTGGCTGGG TGGCCTTCGT TATCACCTAT CCCAAGAGTG TCCATAAGCA GCAGCAGTTG 1440

CAGCATCAAC AGTTTCAGCA GCAGATGGAG GAGAAGCTGC AGCTCTTGCA GCGGCAGCAG 1500

CTCATTTTCC AGCCGCCTAC TGATCTGCCC CCTGACAGCG ACTTCCTGGA GGCAGCCCGT 1560

ACCCGCTCAG AGAGCTCCAC CCACAGCAGT CCTAATGGCA CCCCCCGTGC ATCCAACCAT 1620

TCAAACATAT CCCAGTGTGA GACCGGACAT TCTGCCAATG AGCATGAGGA TACAGAGGAA 1680

GAATCCAACA TTGTCCGAAT TGGAAACATC ACTTTCAACC CCAAAAATGT ACTTGGACAT 1740

GGTGCTGAAG GAACTATTGT TTACAGGGGA CAGTTTGATA ATCGTCCAGT GGCTGTGAAG 1800

AGGATTCTCC CAGAATGCTT TAGCTTTGCT GACCGTGAGG TTCAGCTGCT GCGTGAATCA 1860

GACGAGCATC CAAATGTGAT TCGCTACTTC TGCACTGAGA GAGATCGCCA GTTTCAGTAC 1920

ATCGCCATAG AACTGTGCAA CTCCACATTA CAAGAGTATG TGGAACGAAA GGATTTTAAC 1980

CGTCACGGTT TGGAGCCAGT GACACTGCTA GAGCAAACCA TGTCTGGACT GGCTCATTTA 2040

CATTCTCTTA ATATAGTCCA CAGAGATCTG AAGCCACACA ATATCCTGGT GTCAATGCCG 2100

AACATGCATG GACGTGTGAA GGCCATGATC TCTGACTTCG GCCTGTGTAA GAAGCTGGCA 2160

GTGGGCAGAC ACAGCTTCAG CAGGAAGTCA GGAGTGCCAG GCACCGAGGG CTGGATTGCT 2220

CCTGAAGTAC TCAGTGAGGA TGCAAAGCAC AACCCTACCT GCATGGTGGA CATCTTCTCT 2280

GCAGGATGTG TGTTTTATTA TGTGGTATCT GAAGGCTTCC ACCCCTTTGG AAAATCCTTG 2340

CAACGGCAAG CAAACATTTT ACTTGGTGCC TATTCTCTGG ACCACTTAGA TCCTAACAGA 2400

CATGAGAGTA TTGTGGCCCG AAACCTGATT GAACAGATGT TAAACATGGA GCCTGAGAAG 2460

AGACCCTCGG CTGACAGAGT GCTGAAACAC CCCTTTTTCT GGAGTCTTGA AAAACAGCTG 2520

CATTTCTTTC AGGATGTGAG CGATAGAATT GAGAAGGAGC CATTAGATGG ACCAATCGTG 2580

AGACAACTAG AGAGAGGAGG ACGGGTGGTG GTGAAAGGTG ATTGGAGGGA TCATATCACA 2640

GTGCCTCTAC AGACTGATCT ACGCAAATTT CGCTCTTACA AAGGTGGATC GGTCAGAGAT 2700

CTATTACGTG CCATGAGAAA TAAGAAACAC CACTACCGGG AATTACCGGA GGACGTCCAG 2760

CAGACATTGG GAACCATACC TGATGAATTT GTGTTCTACT TTACCTCCCG TTTCCCTCTT 2820

CTTCTGCAGC ACACACACCT GGCCATGCGG TACTGTGCTG TGGAGCGATC TTTCCTGCCC 2880

TACTACCATG TGTCTGAACT GCTTGCACAC CACACTATAA TGCAGTGTGT GCCACAGACT 2940

TCATCCACAC AGCACAGCTG TGCATCAGAG CCTTCAGGCC TGTCATCGTC CAGTCAGATA 3000

TCAGAATCTC TGCATGAATT ACCAGATGCA CTGTCTGAAA TGGCAGCACC CTCAGAGCAC 3060

ACACAGACGG GCCCAGAGAA GACTGGAGCT CCATAG 3096

Domain Profile

S: 1     fspkdvlGkGaeGtvvfrGsfegrevavkrllsefvdlakrevkllresdehpnviryfc  60

         f+pk+vlG+GaeGt+v+rG+f++r+vavkr+l+e++++a+rev+llresdehpnviryfc

Q: 572   FNPKNVLGHGAEGTIVYRGQFDNRPVAVKRILPECFSFADREVQLLRESDEHPNVIRYFC  631

         789*********************************************************

S: 61    tekdrqfryialelcaaslqdyvedkdlelqkelepisllkqiasGlahlhslkivhrdl  120

         te+drqf+yia+elc+ +lq+yve kd++ +++lep++ll+q++sGlahlhsl+ivhrdl

Q: 632   TERDRQFQYIAIELCNSTLQEYVERKDFN-RHGLEPVTLLEQTMSGLAHLHSLNIVHRDL  690

         *****************************.99****************************

S: 121   kpqnilislpdakgklrvlisdfGlckkldvGkssfsrrsgvsGteGwiapelleeltke  180

         kp+nil+s+p+ +g+++++isdfGlckkl+vG++sfsr+sgv+GteGwiape+l+e++k+

Q: 691   KPHNILVSMPNMHGRVKAMISDFGLCKKLAVGRHSFSRKSGVPGTEGWIAPEVLSEDAKH  750

         ************************************************************

S: 181   rltsavdifslGcvfyyvlskGkhpfGdslkrqanilsgelsldklkeekdeeviaedli  240

         ++t  vdifs+Gcvfyyv+s+G hpfG+sl+rqanil g++sld+l ++++e+++a++li

Q: 751   NPTCMVDIFSAGCVFYYVVSEGFHPFGKSLQRQANILLGAYSLDHLDPNRHESIVARNLI  810

         ************************************************************

S: 241   skmidkdplkrpsakkvlkhplf  263

         ++m++++p krpsa++vlkhp+f

Q: 811   EQMLNMEPEKRPSADRVLKHPFF  833

         **********************9

Domain Sequence
(FASTA)

FNPKNVLGHG AEGTIVYRGQ FDNRPVAVKR ILPECFSFAD REVQLLRESD EHPNVIRYFC 60

TERDRQFQYI AIELCNSTLQ EYVERKDFNR HGLEPVTLLE QTMSGLAHLH SLNIVHRDLK 120

PHNILVSMPN MHGRVKAMIS DFGLCKKLAV GRHSFSRKSG VPGTEGWIAP EVLSEDAKHN 180

PTCMVDIFSA GCVFYYVVSE GFHPFGKSLQ RQANILLGAY SLDHLDPNRH ESIVARNLIE 240

QMLNMEPEKR PSADRVLKHP FF 262

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0016891	; F:endoribonuclease activity, producing 5'-phosphomonoesters
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006397	; P:mRNA processing

KEGG

InterPros

IPR010513	; KEN_RNase_activator.
IPR011009	; Kinase-like_dom.
IPR018391	; PQQ_beta_propeller_repeat.
IPR000719	; Prot_kinase_cat_dom.
IPR006567	; PUG-dom.
IPR011047	; Quinonprotein_ADH-like.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF06479	; Ribonuc_2-5A; 1.

SMARTs

SM00564	; PQQ; 4.
SM00580	; PUG; 1.

Prosites

PS51392	; KEN; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013