EKS-DAR-00350

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DAR-00350

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/TSSK	328.2	9.0E-98	15	266	252

Status

Unreviewed

Ensembl Protein

ENSDARP00000002367

UniProt Accession

Q1LVI1;

Protein Name

Protein Synonyms/Alias

Novel protein similar to vertebrate serine/threonine protein kinase SSTK (SSTK); Si:dkey-11n6.4;

Gene Name

tssk6

Gene Synonyms/Alias

tssk6; si:dkey-11n6.4; DKEY-11N6.4-001;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDARG00000017994	ENSDARP00000002367	ENSDART00000007769

Organism

Danio rerio

Functional Description

Protein Length

268

Protein Sequence
(FASTA)

MSINNVLKGM GYTFLTSIGE GSFSRVKLAT SQKHCCKVAI KIVDRMRGSA DFIQKFLPRE 60

LAVLRRVNHE NIIQMFECIE VAGKRLCIVM EAAEKDLLQK IHEVHHIPKD LSKTMFAQMV 120

SAINYLHQMN IVHRDLKCEN ILLTADEKIK IADFGFARFV EDPSELSHTF CGSRAYTPPE 180

VITGTPYDPK KYDVWSLGVI LYVMVTGTMP YDETNVRRLR LLQQRPLNYP SNVAVEEPCR 240

VFIRTLLQTN PSTRPTIQQV AGHSWLQS 268

Nucleotide Sequence
(FASTA)

ATGTCTATTA ACAACGTTTT GAAAGGCATG GGCTACACTT TCCTCACCTC AATTGGTGAA 60

GGCTCCTTTT CTCGAGTCAA GCTTGCCACC TCGCAGAAGC ACTGCTGTAA GGTGGCTATC 120

AAAATTGTAG ACCGCATGAG GGGCTCTGCG GATTTCATCC AGAAGTTTCT CCCAAGGGAA 180

CTGGCGGTTT TGAGACGGGT GAATCACGAG AACATCATCC AAATGTTCGA ATGCATTGAG 240

GTGGCGGGAA AGCGACTCTG CATCGTGATG GAGGCTGCGG AGAAAGATCT CCTTCAGAAG 300

ATACATGAGG TCCATCATAT TCCTAAAGAC CTAAGTAAAA CCATGTTTGC GCAGATGGTC 360

AGCGCTATCA ACTACCTCCA CCAGATGAAC ATTGTCCACC GAGACCTGAA GTGTGAAAAC 420

ATACTGTTAA CAGCCGATGA GAAAATTAAG ATTGCAGACT TCGGCTTTGC TCGATTCGTT 480

GAAGACCCTT CAGAGCTCAG TCATACCTTC TGTGGATCTC GGGCCTACAC TCCACCGGAG 540

GTCATCACAG GAACGCCGTA TGATCCAAAG AAGTATGACG TATGGAGCCT TGGGGTGATT 600

CTGTATGTCA TGGTGACTGG AACAATGCCA TACGATGAAA CCAACGTCAG ACGACTTCGC 660

CTTCTTCAGC AGAGACCATT GAATTATCCA AGTAATGTCG CCGTTGAGGA ACCATGCCGG 720

GTGTTTATCA GAACTCTGCT CCAGACAAAT CCTTCCACAA GGCCAACTAT TCAACAGGTG 780

GCCGGACATT CTTGGCTGCA GAGCTAA 807

Domain Profile

S: 4     gkkiGeGsyskvkeaysekkklkvavkiidkkkapedyvkkFlPReleilktlkhknivk  63

            iGeGs+s+vk a+s+k+  kva+ki+d+++ ++d+++kFlPRel +l+ ++h+ni++

Q: 15    LTSIGEGSFSRVKLATSQKHCCKVAIKIVDRMRGSADFIQKFLPRELAVLRRVNHENIIQ  74

         578*********************************************************

S: 64    lyeiietsd.kiylvlelaaqgdllelikesgaleeeearklfsqlvsavkylhsldivh  122

         ++e ie++  ++++v+e aa+ dll++i+e  ++ ++ ++++f+q+vsa++ylh+++ivh

Q: 75    MFECIEVAGkRLCIVME-AAEKDLLQKIHEVHHIPKDLSKTMFAQMVSAINYLHQMNIVH  133

         ******99879******.8889**************************************

S: 123   RDlkcenilldkkenvklsDFgFakkvkrskselsktfCGsaaYaaPevlrgikydpkls  182

         RDlkcenill  +e++k++DFgFa+ v+   sels+tfCGs+aY+ Pev++g++ydpk++

Q: 134   RDLKCENILLTADEKIKIADFGFARFVE-DPSELSHTFCGSRAYTPPEVITGTPYDPKKY  192

         ***************************9.9******************************

S: 183   DvWslGvilyvmvvgklPfddsdikkllrsqkkrkvkfpksltlseeckdlilellqlda  242

         DvWslGvilyvmv+g++P+d++++++l    ++r +++p+++ + e c+  i++llq ++

Q: 193   DVWSLGVILYVMVTGTMPYDETNVRRLR-LLQQRPLNYPSNVAVEEPCRVFIRTLLQTNP  251

         *************************986.599****************************

S: 243   kkRltikevlessWl  257

         ++R+ti++v+ +sWl

Q: 252   STRPTIQQVAGHSWL  266

         **************7

Domain Sequence
(FASTA)

LTSIGEGSFS RVKLATSQKH CCKVAIKIVD RMRGSADFIQ KFLPRELAVL RRVNHENIIQ 60

MFECIEVAGK RLCIVMEAAE KDLLQKIHEV HHIPKDLSKT MFAQMVSAIN YLHQMNIVHR 120

DLKCENILLT ADEKIKIADF GFARFVEDPS ELSHTFCGSR AYTPPEVITG TPYDPKKYDV 180

WSLGVILYVM VTGTMPYDET NVRRLRLLQQ RPLNYPSNVA VEEPCRVFIR TLLQTNPSTR 240

PTIQQVAGHS WL 252

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Dasypus novemcinctus"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

dre:557915

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013