EKS-DAR-00551

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DAR-00551

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/MAPKAPK	378.7	2.9E-113	99	382	284

Status

Unreviewed

Ensembl Protein

ENSDARP00000112016

UniProt Accession

F1QAL5;

Protein Name

Protein Synonyms/Alias

Gene Name

mknk1

Gene Synonyms/Alias

mknk1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDARG00000018411	ENSDARP00000111297	ENSDART00000125371
ENSDARG00000018411	ENSDARP00000112016	ENSDART00000123257

Organism

Danio rerio

Functional Description

Protein Length

461

Protein Sequence
(FASTA)

MAEAVPVQRD SFGCSLQLAP LLQALHCSCQ ISSSILGSGK VESRGSLSRV PSTVSQTSTG 60

LGMESSQPIS ITDPSSRRKK KRRRAGDSFT GKFCDLYRLT DELLGQGAYA KVQGCVSLQN 120

GTEYAVKIIE KNAGHSRSRV FREVETLYQC QGNKNILELI QFFEDDSCFY LVFEKLRGGS 180

ILTHIQSRKY FDEREASRVV RDIANALDFL HNKGIAHRDL KPENILCEYT DKVSPVKICD 240

FDLGSGVKLN SACTPITTPE LTTPCGSAEY MAPEVVEVFT DEASFYDKRC DLWSLGVILY 300

ILLSGSPPFT GHCGTNCGWE RGETCRSCQN NLFERIQEGK YEFSDGVWTQ ISADAKDLIS 360

RLLVRDATLR LSAAQVLQHP WVQGNAPERV LPTPRVLQRN CSTKDLTQFA AEAIAFNRQL 420

SQQEEEQEDF GAVVCSMRLS PPSNSRLARR RAQSQALRNN T 461

Nucleotide Sequence
(FASTA)

ATGGCGGAGG CAGTCCCTGT CCAGCGAGAC TCATTCGGCT GCAGTTTACA GCTCGCTCCA 60

CTCCTTCAGG CGCTCCACTG CTCCTGCCAG ATATCCAGTA GCATTCTGGG ATCGGGTAAG 120

GTGGAGAGCC GTGGTTCGCT CTCTCGTGTC CCCAGTACCG TCTCGCAAAC CTCTACAGGA 180

TTAGGAATGG AGAGCAGTCA ACCAATCAGC ATCACAGACC CAAGTTCACG CCGAAAGAAG 240

AAACGCAGAA GAGCCGGAGA CAGTTTCACA GGCAAATTTT GTGATCTATA CAGGCTGACG 300

GATGAGCTGC TGGGTCAGGG AGCTTATGCC AAAGTCCAGG GCTGTGTGAG TTTACAAAAT 360

GGCACGGAGT ATGCGGTAAA GATAATCGAG AAGAATGCTG GTCACAGTCG CAGCCGAGTT 420

TTTAGAGAGG TGGAGACGCT TTACCAGTGT CAAGGAAACA AGAACATTCT GGAGCTGATT 480

CAGTTTTTTG AAGATGACAG CTGCTTTTAT CTGGTGTTTG AGAAGTTACG TGGAGGTTCC 540

ATTTTGACAC ACATCCAGAG TCGAAAATAC TTCGACGAGA GAGAAGCGAG TCGTGTGGTC 600

AGGGATATAG CAAATGCACT AGACTTTCTG CACAACAAAG GAATCGCCCA CCGTGATCTT 660

AAGCCTGAAA ATATCCTCTG TGAATATACT GATAAGGTTT CCCCTGTGAA GATCTGTGAT 720

TTTGATCTTG GCAGTGGAGT AAAGCTGAAC AGTGCCTGTA CCCCAATTAC CACCCCTGAG 780

CTCACCACAC CGTGTGGCTC AGCAGAGTAC ATGGCTCCTG AGGTGGTGGA GGTCTTCACG 840

GACGAAGCTT CATTCTATGA TAAGCGATGT GACCTCTGGA GCCTCGGGGT CATTCTCTAC 900

ATCCTGCTTA GCGGGAGTCC GCCATTTACT GGCCATTGTG GCACCAACTG TGGCTGGGAA 960

CGAGGAGAAA CATGTCGTTC CTGCCAGAAT AATCTGTTTG AGAGGATTCA GGAGGGAAAG 1020

TATGAGTTCA GCGATGGAGT CTGGACACAG ATATCAGCTG ATGCCAAAGA TCTGATCTCG 1080

CGGCTACTGG TGCGAGATGC CACTTTACGG CTAAGTGCCG CTCAGGTCCT GCAGCATCCC 1140

TGGGTGCAGG GGAATGCACC TGAAAGAGTT CTTCCAACTC CTCGTGTTCT ACAAAGAAAC 1200

TGCAGCACTA AAGATCTGAC GCAGTTTGCA GCTGAAGCCA TCGCGTTTAA CCGGCAGCTG 1260

TCGCAACAGG AAGAAGAGCA GGAAGACTTT GGCGCTGTCG TCTGCTCCAT GAGGCTTTCT 1320

CCGCCTTCTA ACTCTAGACT TGCCCGTCGT CGAGCACAGT CTCAAGCACT ACGCAACAAT 1380

ACCTGA 1386

Domain Profile

S: 2     lteevlGeGisgkvlecvkkktgekyalkil.....kdrkkvrrevelhvqasghknive  56

         lt+e+lG+G+++kv+ cv+ ++g++ya+ki+     ++r++v+reve+++q++g+kni+e

Q: 99    LTDELLGQGAYAKVQGCVSLQNGTEYAVKIIeknagHSRSRVFREVETLYQCQGNKNILE  158

         7899********************************************************

S: 57    lidvfensfedekrlllvlekleGGellsriqerkaftekeasevvkdiasalkflhskn  116

         li++fe    d+++++lv+ekl+GG++l++iq+rk+f e+eas+vv+dia+al+flh+k+

Q: 159   LIQFFE----DDSCFYLVFEKLRGGSILTHIQSRKYFDEREASRVVRDIANALDFLHNKG  214

         ******....**************************************************

S: 117   iahrDlkpenlLyeskeknapvklcDfglaketeee........eelktpcltaeyvaPe  168

         iahrDlkpen+L+e ++k++pvk+cDf+l+++++ +        +el+tpc++aey+aPe

Q: 215   IAHRDLKPENILCEYTDKVSPVKICDFDLGSGVKLNsactpittPELTTPCGSAEYMAPE  274

         *******************************9954457889999****************

S: 169   vleaekeeallydksCDlWslGvilyillcGypPfyskkg...........raiskklke  217

         v+e++++ea++ydk+CDlWslGvilyill+G pPf++++g           r+++++l+e

Q: 275   VVEVFTDEASFYDKRCDLWSLGVILYILLSGSPPFTGHCGtncgwergetcRSCQNNLFE  334

         ***************************************99*******************

S: 218   riqegkyefPeeeWsevseeakdlirklLkrdpkerltieevlnhpwv  265

         riqegkyef +  W+++s +akdli++lL+rd++ rl++++vl+hpwv

Q: 335   RIQEGKYEFSDGVWTQISADAKDLISRLLVRDATLRLSAAQVLQHPWV  382

         ***********************************************8

Domain Sequence
(FASTA)

LTDELLGQGA YAKVQGCVSL QNGTEYAVKI IEKNAGHSRS RVFREVETLY QCQGNKNILE 60

LIQFFEDDSC FYLVFEKLRG GSILTHIQSR KYFDEREASR VVRDIANALD FLHNKGIAHR 120

DLKPENILCE YTDKVSPVKI CDFDLGSGVK LNSACTPITT PELTTPCGSA EYMAPEVVEV 180

FTDEASFYDK RCDLWSLGVI LYILLSGSPP FTGHCGTNCG WERGETCRSC QNNLFERIQE 240

GKYEFSDGVW TQISADAKDL ISRLLVRDAT LRLSAAQVLQ HPWV 284

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013