EPS-DAR-00077

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-DAR-00077

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPP/PP7	284.1	2.4E-84	129	327	199

Status

Unreviewed

Ensembl Protein

ENSDARP00000009463

UniProt Accession

F1QPP2;

Protein Name

Serine/threonine-protein phosphatase

Protein Synonyms/Alias

Gene Name

ppef1

Gene Synonyms/Alias

ppef1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDARG00000020191	ENSDARP00000009463	ENSDART00000003475

Organism

Danio rerio

Functional Description

Protein Length

718

Protein Sequence
(FASTA)

MGCGTSIAIE NQTRPSETAI KAAILIQRWY RRYVAHLEMR RRYTWNIFQS IEYAGEQDQL 60

QLSSFFTFML DNFTQINGNG PDLISHLLDS VVDPLTEEVR QLKYEQIMVP ESYSGPRLSF 120

PLSVTDTNAL LSAFKEEQTL HGKYVLQLLY ETKKFLKQMP NVIYLSTSYA KEITICGDLH 180

GRLDDLLLIF YKNGLPSAEN PYIFNGDFVD RGKKSTEIII ILFAFVLLYP DHMHLNRGNH 240

EDHIMNLRYG FTREVMQKYK THGREILQLL QDVFSLLPVA TVIDNKVLIV HGGISDKTDL 300

DFLSTVERHK VKSALRLPKR STDHLTVRSC SRSSSRNRGR NSRSSSRHSS RSRRKKLSKQ 360

GSRSSSSSSS SSSSSSMCSP RVSAKNTPRR PPPSPTDMLQ VPFLDSFVSL EPPELPREEL 420

EWQQVVDILW SDPKHQNGCS PNSFRGGGCY FGPDVTQTLL QKHGLCLLIR SHECKQEGYE 480

LCHNGQVITI FSASNYYEEG SNRGAYVKLG PELVPRFFQY QVSRSTRKLT LHQRVRVAEG 540

SALRALKEKL YAHRSELMAA FQQYDINNTG RISTSEWAQV VESVLRLDLP WRTLRPRLAR 600

LGTDGNVEYE SCFEDISPGE PIPPVTPNLA ETLYRYRTDL EIIFNIIDKD HSGQISIEEF 660

RQTWKLFSSH LGVAVNDQTI DDMARSIDFN KDGSIDFTEF LEAFRVVHKL DVKEQQQG 718

Nucleotide Sequence
(FASTA)

ATGGGATGCG GCACATCCAT TGCCATTGAG AACCAAACAC GACCCTCAGA AACAGCCATA 60

AAAGCTGCCA TACTGATCCA GCGTTGGTAC AGACGCTATG TTGCTCACCT GGAGATGCGA 120

AGACGCTACA CGTGGAACAT CTTTCAGTCC ATTGAGTATG CAGGAGAACA GGACCAGCTA 180

CAGCTCTCAA GTTTCTTCAC TTTCATGTTG GACAACTTCA CTCAGATTAA TGGGAATGGA 240

CCAGACTTGA TCTCCCACCT GCTGGACTCT GTGGTTGATC CTCTGACGGA GGAGGTCAGG 300

CAGCTGAAGT ACGAGCAGAT TATGGTGCCG GAGTCGTACA GCGGCCCTCG TCTCTCCTTC 360

CCGCTGAGCG TGACTGATAC CAATGCCCTG CTCAGTGCCT TTAAAGAGGA GCAGACTCTT 420

CATGGGAAGT ATGTGCTGCA GTTACTGTAT GAAACCAAGA AGTTCCTGAA ACAAATGCCA 480

AACGTCATTT ATCTGTCAAC GTCCTATGCC AAAGAAATAA CGATCTGTGG CGATCTGCAT 540

GGAAGACTGG ATGACTTGCT GCTTATATTT TACAAGAACG GTCTGCCCTC TGCGGAAAAC 600

CCCTACATAT TCAATGGAGA CTTTGTGGAT CGAGGAAAGA AATCTACAGA GATTATCATC 660

ATTCTCTTTG CCTTCGTTTT GCTCTACCCC GACCACATGC ATCTGAACAG GGGAAACCAT 720

GAGGACCACA TCATGAACCT CAGATATGGA TTCACCAGAG AAGTCATGCA GAAGTACAAG 780

ACTCATGGCA GGGAAATCCT GCAGCTCCTT CAGGATGTGT TCAGTCTTCT TCCTGTTGCA 840

ACTGTAATAG ACAACAAAGT GCTTATTGTT CATGGTGGCA TATCGGACAA AACTGATCTG 900

GACTTTCTGA GCACTGTTGA AAGGCATAAA GTGAAGTCAG CTCTGCGTTT GCCGAAGCGC 960

AGCACTGATC ATCTGACGGT GCGCTCGTGC AGTCGCAGCA GCAGCAGAAA CAGGGGCAGA 1020

AACAGCAGAT CCTCAAGCCG ACACTCGTCC CGCAGCAGAA GGAAGAAGCT CAGCAAGCAG 1080

GGCAGCCGCT CCTCCTCTTC CTCATCCTCC TCATCCTCCT CTTCCTCCAT GTGTTCGCCA 1140

CGGGTCTCAG CCAAAAACAC TCCACGCCGC CCTCCACCGA GCCCCACAGA CATGCTCCAA 1200

GTGCCCTTTC TGGACTCATT CGTGTCCTTG GAGCCACCAG AGCTGCCCAG AGAAGAGCTG 1260

GAGTGGCAGC AGGTTGTGGA TATCCTGTGG AGTGACCCTA AACATCAGAA TGGCTGCAGT 1320

CCCAATTCTT TTCGCGGTGG AGGCTGTTAC TTCGGGCCAG ACGTGACACA GACACTGCTG 1380

CAGAAACACG GCCTCTGTCT GCTCATCAGA TCACACGAAT GCAAACAGGA GGGCTATGAG 1440

CTTTGCCACA ATGGACAGGT TATCACTATA TTCTCTGCAT CAAACTACTA TGAAGAGGGC 1500

AGTAACCGTG GGGCTTATGT CAAACTGGGG CCTGAACTTG TCCCTCGCTT CTTCCAGTAT 1560

CAAGTCAGTC GAAGCACCAG AAAACTCACC CTCCATCAGA GGGTTCGAGT AGCTGAAGGT 1620

TCTGCACTCA GGGCTCTGAA AGAGAAACTT TATGCTCATC GCTCTGAACT CATGGCTGCC 1680

TTTCAACAGT ATGACATCAA TAACACAGGC CGTATCTCCA CTAGTGAGTG GGCACAGGTG 1740

GTGGAGTCTG TTCTGCGTTT GGATCTGCCA TGGAGAACCC TGCGCCCACG CCTGGCCCGT 1800

CTTGGCACAG ATGGCAATGT GGAATATGAA TCCTGTTTCG AGGACATCAG TCCTGGAGAG 1860

CCCATCCCTC CGGTGACCCC GAACTTAGCT GAAACACTTT ATAGATATAG AACTGACCTG 1920

GAGATCATTT TTAACATCAT CGATAAGGAT CACTCAGGTC AGATCTCCAT CGAGGAGTTT 1980

CGTCAGACCT GGAAGCTCTT CAGCTCTCAT TTAGGGGTGG CTGTGAATGA CCAGACCATA 2040

GACGACATGG CTCGAAGCAT AGACTTTAAC AAAGACGGCA GCATTGATTT TACTGAGTTC 2100

CTGGAGGCCT TCAGGGTGGT GCATAAACTG GATGTCAAAG AGCAACAGCA GGGTTAA 2157

Domain Profile

S: 3     lllevfkkkrilhakyvlevlfeakkvlkqlpnishvstavskevtvvGdlhGklddlll  62

          ll +fk+++ lh kyvl++l+e+kk lkq+pn+  +st+ +ke+t++GdlhG+lddlll

Q: 129   ALLSAFKEEQTLHGKYVLQLLYETKKFLKQMPNVIYLSTSYAKEITICGDLHGRLDDLLL  188

         5899********************************************************

S: 63    vlkknGlPsernpyvfnGdfvdrGkrglevllvllslflvfPnavylnrGnhedkvmnar  122

         +++knGlPs +npy+fnGdfvdrGk++ e++++l ++ l++P++++lnrGnhed++mn+r

Q: 189   IFYKNGLPSAENPYIFNGDFVDRGKKSTEIIIILFAFVLLYPDHMHLNRGNHEDHIMNLR  248

         ************************************************************

S: 123   yGfekevlskykrkgkrilrileevyewlPlgsivdsrvlvvhGGlsestsldllksver  182

         yGf++ev++kyk++g+ il++l++v+  lP+++++d++vl+vhGG+s+ t+ld l +ver

Q: 249   YGFTREVMQKYKTHGREILQLLQDVFSLLPVATVIDNKVLIVHGGISDKTDLDFLSTVER  308

         ************************************************************

S: 183   kkrksvllpPeessrdlgrl  202

         +k+ks l+ P+ s  d+ ++

Q: 309   HKVKSALRLPKRS-TDHLTV  327

         **********955.454444

Domain Sequence
(FASTA)

ALLSAFKEEQ TLHGKYVLQL LYETKKFLKQ MPNVIYLSTS YAKEITICGD LHGRLDDLLL 60

IFYKNGLPSA ENPYIFNGDF VDRGKKSTEI IIILFAFVLL YPDHMHLNRG NHEDHIMNLR 120

YGFTREVMQK YKTHGREILQ LLQDVFSLLP VATVIDNKVL IVHGGISDKT DLDFLSTVER 180

HKVKSALRLP KRSTDHLTV 199

Keyword

Calcium; Complete proteome; Hydrolase; Iron; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Drosophila melanogaster"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005509	; F:calcium ion binding
GO:0005506	; F:iron ion binding
GO:0030145	; F:manganese ion binding
GO:0004721	; F:phosphoprotein phosphatase activity
GO:0050906	; P:detection of stimulus involved in sensory perception

KEGG

InterPros

IPR011992	; EF-hand-like_dom.
IPR018247	; EF_Hand_1_Ca_BS.
IPR018249	; EF_HAND_2.
IPR002048	; EF_hand_Ca-bd.
IPR000048	; IQ_motif_EF-hand-BS.
IPR004843	; Metallo_PEstase_dom.
IPR013235	; PPP_dom.
IPR012008	; Ser/Thr-Pase_EF-hand_contain.
IPR006186	; Ser/Thr-sp_prot-phosphatase.

Pfam

PF13202	; EF_hand_3; 1.
PF00149	; Metallophos; 1.
PF08321	; PPP5; 1.

SMARTs

SM00054	; EFh; 3.
SM00015	; IQ; 1.
SM00156	; PP2Ac; 1.

Prosites

PS00018	; EF_HAND_1; 3.
PS50222	; EF_HAND_2; 3.
PS00125	; SER_THR_PHOSPHATASE; 1.

Prints

PR00114

; STPHPHTASE.

Created Date

20-Feb-2013