EPS-DAR-00054

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-DAR-00054

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	224.8	3.2E-66	97	374	278

Status

Unreviewed

Ensembl Protein

ENSDARP00000006004

UniProt Accession

A2ATY1;

Protein Name

Protein Synonyms/Alias

Novel protein similar to vertebrate protein phosphatase 1D magnesium-dependent, delta isoform (PPM1D) (Zgc:103518);

Gene Name

CH211-127D4.1

Gene Synonyms/Alias

CH211-127D4.1; ppm1db; CH211-127D4.1-001;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDARG00000021380	ENSDARP00000006004	ENSDART00000014028

Organism

Danio rerio

Functional Description

Protein Length

534

Protein Sequence
(FASTA)

MDMNCDLSLR VSVFSEQGGR KYMEDLTEVI VELEPTEDEL QAAGHADPKP DQEPVSDSEP 60

PDCSNNPLPV LITWRNPLST EEADGTDEPG TQPAAADSRR SVAFFAVFDG HGGREAAMFA 120

RDHLWDFLKK QRGFWSKDYR KVCSAIRKGF IACHHAMWKK LPEWPKTLTG LPSTSGTTAS 180

VVVIRGDHMF VAHVGDSSVV LGVREDPSDK VIKAVEVTQD HKPELPKEKQ RIEGLGGSVV 240

KKSGVNRVVW KRPRLSHNGP VRRSTPIDQI PFLAVARALG DLWSYDFYSG EFVVSPEPDT 300

SVVTLDPRRH RYIIVGSDGL WNMVPPQEAV TVCQSHDEAV APFGMSVARR LGCHALMRWR 360

QRMLRADNTS VIVIALPEPG KPHLPMHRDE VILSLAEGPH CDPATGSRSN TPLIKTPDPD 420

LSSASSESLP ALERRNGLSG VSLCAEAPLE ENLPYIELAD KTDLTVCPSG GKRTLDTPLS 480

SPVAKRPRRS PLAPSSSRKR TTDRSLPRRN TTKSQKRTPS VSILQHRKAA LCVC 534

Nucleotide Sequence
(FASTA)

ATGGATATGA ATTGCGACCT ATCGCTGCGA GTGAGCGTCT TCTCCGAACA AGGAGGAAGG 60

AAATACATGG AGGATTTAAC GGAGGTGATC GTGGAGCTGG AACCCACCGA AGATGAGTTG 120

CAGGCGGCGG GACACGCTGA TCCAAAGCCG GACCAAGAGC CGGTCTCTGA TAGCGAACCG 180

CCGGACTGCT CAAACAATCC TTTACCGGTT CTGATAACGT GGAGAAACCC GCTGTCGACC 240

GAGGAGGCTG ACGGTACGGA TGAGCCTGGG ACTCAACCGG CGGCGGCGGA CAGCAGGAGA 300

TCGGTCGCCT TTTTTGCCGT GTTTGACGGA CACGGAGGGC GAGAAGCTGC GATGTTTGCT 360

CGAGATCACC TCTGGGATTT TCTCAAGAAG CAGCGGGGAT TCTGGTCTAA GGATTACCGG 420

AAGGTTTGTT CCGCAATTCG GAAGGGCTTT ATCGCATGTC ATCACGCGAT GTGGAAAAAG 480

CTTCCTGAAT GGCCCAAGAC TTTAACTGGT CTCCCCAGTA CTTCGGGCAC TACAGCCAGT 540

GTGGTGGTCA TCAGAGGGGA CCATATGTTT GTGGCTCATG TTGGGGATTC ATCTGTGGTT 600

CTGGGCGTGA GGGAGGACCC CTCGGATAAG GTCATCAAAG CTGTGGAGGT CACTCAAGAC 660

CACAAGCCCG AGCTCCCAAA AGAGAAGCAG AGAATTGAGG GACTGGGAGG AAGTGTGGTG 720

AAGAAGTCTG GTGTGAACCG TGTGGTGTGG AAACGACCTA GGCTAAGTCA CAATGGACCG 780

GTCAGGAGGA GCACCCCAAT CGATCAGATC CCCTTTCTCG CTGTTGCCAG GGCTCTGGGT 840

GATCTATGGA GTTATGACTT CTACAGTGGA GAGTTTGTGG TGTCTCCTGA GCCTGACACC 900

AGTGTGGTGA CCCTGGACCC AAGACGGCAT CGTTACATCA TCGTTGGCAG TGATGGGCTT 960

TGGAACATGG TGCCACCGCA AGAGGCAGTA ACTGTGTGCC AGAGCCACGA TGAGGCTGTG 1020

GCGCCTTTTG GGATGTCGGT TGCACGTCGG TTGGGTTGCC ATGCATTGAT GCGATGGCGT 1080

CAGCGAATGC TTCGTGCCGA CAACACCAGC GTCATAGTTA TCGCCCTTCC TGAGCCTGGC 1140

AAACCACACT TACCTATGCA CAGAGACGAG GTCATACTCA GCCTAGCAGA GGGTCCACAC 1200

TGTGATCCAG CAACAGGATC CCGCTCCAAC ACGCCACTCA TCAAGACTCC AGATCCAGAC 1260

CTGTCCTCAG CCAGCAGTGA GTCTTTGCCA GCGCTGGAGA GGAGGAACGG CTTGTCAGGA 1320

GTAAGTCTGT GTGCTGAAGC CCCGCTAGAG GAAAACCTCC CTTACATTGA GCTCGCTGAT 1380

AAAACCGACT TGACTGTGTG TCCTAGTGGG GGCAAGCGGA CCCTAGACAC TCCCCTGTCC 1440

TCTCCGGTGG CCAAGAGGCC CCGACGCAGC CCCCTCGCCC CCAGCAGCTC CCGCAAGAGG 1500

ACTACCGATC GCTCCCTCCC CAGGCGCAAC ACCACCAAGA GTCAAAAACG GACTCCCAGC 1560

GTCTCCATAC TACAGCACCG CAAAGCAGCG CTCTGTGTCT GCTGA 1605

Domain Profile

S: 27    kspekkdrlaffgvyDGhggsevakfcseklheilaeelesseseerkvkkalakaFlst  86

         +   +++ +aff+v+DGhgg+e+a f++++l+++l+++  + +++ rkv++a++k+F+++

Q: 97    D---SRRSVAFFAVFDGHGGREAAMFARDHLWDFLKKQRGFWSKDYRKVCSAIRKGFIAC  153

         2...23349***************************************************

S: 87    deel.....kvleeksldidksGstavvalikdsklyvanvGdSravLcrngk.......  134

         + ++     +++++ +  +++sG+ta+v++i++++++va+vGdS +vL+  ++

Q: 154   HHAMwkklpEWPKTLTGLPSTSGTTASVVVIRGDHMFVAHVGDSSVVLGVREDpsdkvik  213

         *************************************************96655799999

S: 135   avelssdHkpsredEleRieeaggsvilkdga.Rv.....................lGvL  172

         ave+++dHkp+ ++E++Rie  ggsv++k+g+ Rv                     +++L

Q: 214   AVEVTQDHKPELPKEKQRIEGLGGSVVKKSGVnRVvwkrprlshngpvrrstpidqIPFL  273

         9***********************************************************

S: 173   avsRalGdlylk......pyvtpePevtshrltsede.fliLasDGlwdvvsneeavslv  225

         av+RalGdl+++      ++v+peP++++++l+++ + ++i +sDGlw++v+++eav+++

Q: 274   AVARALGDLWSYdfysgeFVVSPEPDTSVVTLDPRRHrYIIVGSDGLWNMVPPQEAVTVC  333

         **********************************9999**********************

S: 226   rdvle.kkeaeqeaakkLvklalargsk.....dnvsaivv  260

         +++ e       ++a +L  +al r+++     dn+s+iv+

Q: 334   QSHDEaVAPFGMSVARRLGCHALMRWRQrmlraDNTSVIVI  374

         ****97333445666666666666666666666*****997

Domain Sequence
(FASTA)

DSRRSVAFFA VFDGHGGREA AMFARDHLWD FLKKQRGFWS KDYRKVCSAI RKGFIACHHA 60

MWKKLPEWPK TLTGLPSTSG TTASVVVIRG DHMFVAHVGD SSVVLGVRED PSDKVIKAVE 120

VTQDHKPELP KEKQRIEGLG GSVVKKSGVN RVVWKRPRLS HNGPVRRSTP IDQIPFLAVA 180

RALGDLWSYD FYSGEFVVSP EPDTSVVTLD PRRHRYIIVG SDGLWNMVPP QEAVTVCQSH 240

DEAVAPFGMS VARRLGCHAL MRWRQRMLRA DNTSVIVI 278

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>