EKS-DAR-00053

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DAR-00053

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CK1/VRK	380.9	5.5E-114	26	291	266

Status

Unreviewed

Ensembl Protein

ENSDARP00000092215

UniProt Accession

B8JHS7;

Protein Name

Protein Synonyms/Alias

Vaccinia related kinase 2;

Gene Name

vrk2

Gene Synonyms/Alias

vrk2; DKEY-173F1.1-001;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDARG00000021547	ENSDARP00000038349	ENSDART00000036419
ENSDARG00000021547	ENSDARP00000092215	ENSDART00000101441

Organism

Danio rerio

Functional Description

Protein Length

356

Protein Sequence
(FASTA)

MPPKKYTLPR PLPDGCILTD SEKKNWRIGK MIGKGGFGLI YLASQDVNVP VRDDADFVIK 60

VEYHENGPLF SELKFYQRAA KPETMSKWMK SKQLGFLGIP TYWGSGLTES NGTRYRFMVM 120

DRLGTDLQKV LIDNGGQLRK TSVLQLGVLM LDVLEYIHDN EYVHADIKAA NLLLGYRDPN 180

KVYLADYGLS YRYCPNGEHK EYKENPKKGH NGTIEYTSID AHKGVAASRR GDLKVLGYCL 240

LHWQCGTLPW LPSLKNPAEV QEAKAKLMSN LPDSVLKMST SSSSMEIAQF LSRVKDLGYN 300

EKPDYQALRM VLSATGLQGP LDLSRQRASE TVRPTTQRAA SQPKTTEKKW GDQSLR 356

Nucleotide Sequence
(FASTA)

ATGCCTCCAA AGAAATACAC ACTACCTCGT CCACTTCCAG ATGGATGCAT TTTAACGGAT 60

TCAGAAAAGA AGAACTGGCG CATCGGGAAA ATGATTGGAA AAGGAGGATT TGGGCTGATT 120

TATTTGGCTT CTCAGGATGT GAATGTCCCT GTTCGAGATG ATGCTGATTT TGTGATCAAA 180

GTGGAATATC ATGAAAATGG ACCTTTATTC TCAGAACTCA AATTTTACCA ACGGGCAGCA 240

AAGCCAGAAA CTATGAGCAA ATGGATGAAG TCAAAACAAC TGGGTTTTTT GGGTATCCCA 300

ACTTACTGGG GTTCTGGACT GACTGAAAGT AACGGAACAA GGTACAGGTT TATGGTAATG 360

GATCGGCTGG GTACAGATCT GCAGAAAGTG TTAATAGATA ATGGTGGACA ACTGAGGAAG 420

ACCAGCGTGC TACAATTGGG TGTACTAATG CTGGATGTGC TGGAATATAT TCATGACAAC 480

GAATATGTCC ATGCTGATAT TAAGGCTGCC AATCTCTTAT TGGGATACAG AGATCCAAAC 540

AAGGTGTACT TGGCTGACTA TGGTCTCTCA TACAGATACT GTCCTAATGG CGAGCATAAA 600

GAGTACAAAG AGAACCCCAA GAAAGGACAC AATGGCACTA TTGAGTACAC AAGCATTGAC 660

GCTCACAAAG GAGTAGCCGC ATCCCGGCGA GGAGACTTGA AGGTGTTGGG CTACTGCTTG 720

CTTCACTGGC AGTGTGGAAC TCTGCCCTGG CTCCCTTCTC TTAAAAATCC AGCTGAGGTT 780

CAGGAGGCCA AGGCCAAGTT GATGTCTAAC CTGCCAGATT CTGTTCTGAA GATGTCTACC 840

TCCAGCTCAA GCATGGAGAT TGCCCAGTTC CTGTCCAGAG TGAAAGACCT TGGCTATAAT 900

GAAAAGCCAG ACTACCAGGC TCTCAGAATG GTTCTGTCTG CGACCGGGCT GCAGGGCCCA 960

TTGGACCTCT CCAGGCAGAG AGCTTCAGAG ACGGTCAGGC CAACTACACA AAGGGCCGCA 1020

AGCCAACCCA AGACTACTGA GAAAAAATGG GGAGATCAAA GCCTGCGGTG A 1071

Domain Profile

S: 1     wklgkkigkggfGeiyla..ltckkeekdaklvvkvepkenGpLfvelkfyqraakkeqi  58

         w++gk+igkggfG iyla   +   + +da++v+kve++enGpLf+elkfyqraak+e++

Q: 26    WRIGKMIGKGGFGLIYLAsqDVNVPVRDDADFVIKVEYHENGPLFSELKFYQRAAKPETM  85

         9*****************85556667899*******************************

S: 59    kkwkkkkklkllgiPtliasGlhefegekyRflvlprlgrdLqklleqngkrlsektvlq  118

         +kw+k k+l +lgiPt+++sGl+e +g++yRf+v++rlg+dLqk+l +ng++l++ +vlq

Q: 86    SKWMKSKQLGFLGIPTYWGSGLTESNGTRYRFMVMDRLGTDLQKVLIDNGGQLRKTSVLQ  145

         ************************************************************

S: 119   lavrlldvleylHeneYvHgdikAanllleeeeasqvyLvdyGlayrycpegkhkeyked  178

         l+v +ldvley+H+neYvH+dikAanlll+++++++vyL+dyGl+yrycp+g+hkeyke+

Q: 146   LGVLMLDVLEYIHDNEYVHADIKAANLLLGYRDPNKVYLADYGLSYRYCPNGEHKEYKEN  205

         ************************************************************

S: 179   krraHdGtleftslDaHkGvapsrRsDleiLgYcllkWltgkLPWeallkdpekvqkake  238

         +++ H+Gt+e+ts+DaHkGva srR+Dl++LgYcll+W +g+LPW   lk+p +vq+ak

Q: 206   PKKGHNGTIEYTSIDAHKGVAASRRGDLKVLGYCLLHWQCGTLPWLPSLKNPAEVQEAKA  265

         ************************************************************

S: 239   kfldelpellkkllkkkssseelakyl  265

         k++ +lp+++ k+ +++ss  e+a++l

Q: 266   KLMSNLPDSVLKMSTSSSSM-EIAQFL  291

         ************99988877.899886

Domain Sequence
(FASTA)

WRIGKMIGKG GFGLIYLASQ DVNVPVRDDA DFVIKVEYHE NGPLFSELKF YQRAAKPETM 60

SKWMKSKQLG FLGIPTYWGS GLTESNGTRY RFMVMDRLGT DLQKVLIDNG GQLRKTSVLQ 120

LGVLMLDVLE YIHDNEYVHA DIKAANLLLG YRDPNKVYLA DYGLSYRYCP NGEHKEYKEN 180

PKKGHNGTIE YTSIDAHKGV AASRRGDLKV LGYCLLHWQC GTLPWLPSLK NPAEVQEAKA 240

KLMSNLPDSV LKMSTSSSSM EIAQFL 266

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>