EKS-DAR-00547

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DAR-00547

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/MAPKAPK	410.1	7.6E-123	23	304	282

Status

Unreviewed

Ensembl Protein

ENSDARP00000035123

UniProt Accession

A2BGS0;

Protein Name

Protein Synonyms/Alias

Mitogen-activated protein kinase-activated protein kinase 5;

Gene Name

mapkapk5

Gene Synonyms/Alias

mapkapk5; CH211-157P22.7-001;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDARG00000028082	ENSDARP00000035123	ENSDART00000036845
ENSDARG00000028082	ENSDARP00000113922	ENSDART00000145966

Organism

Danio rerio

Functional Description

Protein Length

471

Protein Sequence
(FASTA)

MTEDSTVDRF IKETSILEEY NINWTQKLGA GISGPVRVCV KKSTQERFAL KILIDRPKAR 60

NEVRLHMMCA SHPNIVKIME VYANSVQFPH ESSPRARLLI VMEMMEGGEL FHRISQHKHF 120

TEKMASQVTK QISLALQHCH SLNIAHRDLK PENLLFKDNS LDAPVKLCDF GFAKIDQGDL 180

MTPQFTPYYV APQVLEAQRR HQKEKSGIIP TSPTPYTYNK SCDLWSLGVI VYVMLCGYPP 240

FYSKHHSRTI PKDMRKKIMT GSFDFPEEEW SQISEMAKDI VRKLLKVKPE ERLTIEGVLA 300

HPWLNCTEAL DNVLPSAQMM MDKAVVAGIQ QAHAEQLANM RIQDLNLSLK PLNSVNNPIL 360

RKRKLLGTKP NDELFINDPE NEVEDTNVAL EKLRDVIAQC ILPQAGDSDD EKLNEVMHEA 420

WRLNRDCKLL RDGLHGLCWD GRSFSDRVDR LKLAEIVKQA IEEKTNLQDS P 471

Nucleotide Sequence
(FASTA)

ATGACTGAAG ACAGCACCGT GGACAGGTTC ATAAAGGAGA CGTCTATCCT GGAAGAGTAT 60

AACATCAACT GGACGCAGAA GCTAGGAGCT GGAATCAGTG GTCCCGTCAG GGTTTGTGTG 120

AAGAAATCGA CACAAGAACG ATTTGCCCTA AAAATCTTGA TTGACCGACC CAAAGCTCGT 180

AATGAGGTTC GGCTTCATAT GATGTGTGCC TCTCACCCTA ACATAGTTAA AATAATGGAG 240

GTGTACGCCA ACAGTGTACA GTTTCCTCAT GAATCCAGTC CAAGGGCAAG GTTATTGATT 300

GTGATGGAGA TGATGGAAGG CGGAGAGTTG TTCCACAGAA TCAGCCAGCA CAAGCACTTT 360

ACAGAGAAGA TGGCCAGTCA GGTCACTAAA CAGATAAGCC TTGCATTGCA ACACTGTCAT 420

TCGTTAAATA TTGCACATCG AGACCTGAAA CCAGAGAATC TGCTCTTCAA GGATAATTCA 480

CTGGATGCCC CTGTAAAACT GTGTGATTTC GGTTTTGCCA AAATCGATCA GGGTGATTTG 540

ATGACCCCGC AGTTCACGCC GTACTATGTA GCACCCCAGG TGCTGGAGGC ACAAAGGCGC 600

CACCAGAAAG AGAAGTCTGG AATTATACCT ACCTCACCAA CCCCTTACAC ATACAACAAG 660

AGCTGTGACC TGTGGTCTTT GGGGGTGATC GTCTACGTAA TGCTCTGTGG ATATCCTCCG 720

TTTTACTCCA AACACCACAG CCGCACCATC CCGAAAGACA TGCGCAAAAA AATCATGACC 780

GGCAGCTTTG ACTTTCCTGA GGAGGAGTGG AGCCAGATAT CAGAGATGGC CAAAGACATC 840

GTCCGCAAGC TTCTTAAAGT AAAGCCGGAG GAGAGACTGA CCATAGAGGG TGTTTTAGCT 900

CATCCCTGGC TCAATTGCAC CGAGGCTCTG GACAATGTGC TTCCCTCCGC TCAGATGATG 960

ATGGACAAGG CAGTTGTAGC AGGAATCCAA CAGGCTCATG CAGAGCAGCT GGCCAACATG 1020

AGGATACAAG ACCTCAATCT GAGTCTGAAA CCCCTCAACT CCGTTAACAA CCCCATTCTG 1080

AGAAAGAGAA AGCTGCTGGG CACCAAACCC AATGACGAGC TGTTCATCAA TGACCCAGAG 1140

AATGAGGTGG AGGACACCAA TGTGGCTCTG GAAAAACTAA GGGATGTGAT CGCACAGTGC 1200

ATATTACCAC AGGCTGGTGA CAGTGATGAC GAAAAGCTAA ATGAAGTAAT GCATGAAGCT 1260

TGGCGCTTGA ATCGTGATTG CAAACTTCTC AGAGATGGAT TGCATGGGTT ATGTTGGGAT 1320

GGTAGATCTT TTTCCGACAG AGTGGACCGC TTAAAGCTGG CTGAAATCGT CAAACAGGCC 1380

ATTGAAGAAA AGACAAATTT ACAAGACTCC CCATAG 1416

Domain Profile

S: 2     lteevlGeGisgkvlecvkkktgekyalkilkdrkkvrrevelhvqasghknivelidvf  61

         +++++lG+Gisg v+ cvkk+t+e++alkil dr+k+r+ev+lh+++++h+niv++++v+

Q: 23    NWTQKLGAGISGPVRVCVKKSTQERFALKILIDRPKARNEVRLHMMCASHPNIVKIMEVY  82

         689*********************************************************

S: 62    ensfe......dekrlllvlekleGGellsriqerkaftekeasevvkdiasalkflhsk  115

         +ns++      +++rll+v+e++eGGel++ri+++k+ftek as+v+k+i+ al+++hs

Q: 83    ANSVQfphessPRARLLIVMEMMEGGELFHRISQHKHFTEKMASQVTKQISLALQHCHSL  142

         ****99999999************************************************

S: 116   niahrDlkpenlLyeskeknapvklcDfglaketeeeeelktpcltaeyvaPevleaeke  175

         niahrDlkpenlL+++++ +apvklcDfg+ak   ++ +l+tp++t++yvaP+vlea+++

Q: 143   NIAHRDLKPENLLFKDNSLDAPVKLCDFGFAK--IDQGDLMTPQFTPYYVAPQVLEAQRR  200

         ********************************..89***********************9

S: 176   e.............allydksCDlWslGvilyillcGypPfyskk.graiskklkeriqe  221

         +             +++y+ksCDlWslGvi+y++lcGypPfysk+ +r+i+k+++++i++

Q: 201   HqkeksgiiptsptPYTYNKSCDLWSLGVIVYVMLCGYPPFYSKHhSRTIPKDMRKKIMT  260

         99*****************************************9979*************

S: 222   gkyefPeeeWsevseeakdlirklLkrdpkerltieevlnhpwv  265

         g+++fPeeeWs++se+akd++rklLk++p+erltie vl+hpw+

Q: 261   GSFDFPEEEWSQISEMAKDIVRKLLKVKPEERLTIEGVLAHPWL  304

         *******************************************6

Domain Sequence
(FASTA)

NWTQKLGAGI SGPVRVCVKK STQERFALKI LIDRPKARNE VRLHMMCASH PNIVKIMEVY 60

ANSVQFPHES SPRARLLIVM EMMEGGELFH RISQHKHFTE KMASQVTKQI SLALQHCHSL 120

NIAHRDLKPE NLLFKDNSLD APVKLCDFGF AKIDQGDLMT PQFTPYYVAP QVLEAQRRHQ 180

KEKSGIIPTS PTPYTYNKSC DLWSLGVIVY VMLCGYPPFY SKHHSRTIPK DMRKKIMTGS 240

FDFPEEEWSQ ISEMAKDIVR KLLKVKPEER LTIEGVLAHP WL 282

Keyword

Complete proteome; Kinase; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>