EKS-DAR-00368

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DAR-00368

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/MLCK	380.0	1.0E-113	269	522	254

Status

Unreviewed

Ensembl Protein

ENSDARP00000048627

UniProt Accession

F1QAR7;

Protein Name

Protein Synonyms/Alias

Gene Name

mylk2

Gene Synonyms/Alias

mylk2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDARG00000031698	ENSDARP00000115941	ENSDART00000133801
ENSDARG00000031698	ENSDARP00000048627	ENSDART00000048628

Organism

Danio rerio

Functional Description

Protein Length

555

Protein Sequence
(FASTA)

MPPTQNHVLI PIRTPAIASQ KTEAQEIRKV PPPNIKVPVA AAVIIPNTTG QTCTESVNVT 60

PANHILPKTT VTPAAPPLVN NNTPKLTVSE VPKDFKPSHK YPQTSLPPSV AAQRSEQTPV 120

NMPTTKTTTP QDAALFPPTH KPPKTVGLSV TTATKEASSL RQVHSCPNSL QRLQVPGLKA 180

DLVHTVTSTL TSKKRATETV GAAKLTSDGI QIKISSATDK NSAQTKSYNP PKLCFKVIDD 240

VSPQPAPFAH RFVALKSSPP PCDTFSIHTR EVLGGGRFGK VHKCTETRTG MRLAAKIINT 300

RNSKERDMAL NEMQVMNQLS HPNILQLYEA FEVKNQVVLI LEYVEGGELF ERIVDESSPL 360

TEVDAMVFVK QICEGVQYMH QMYVLHLDLK PENILLVNRS SHQVKIIDFG LARRYKPREK 420

LKVSFGTPEF LAPEVVNFDF VSFPTDMWTL GVVTYMLLSG LSPFLGDDDG QTLNNVLMGN 480

WYFDEDAFEH VSADARDFVS NLLIRERSGR MSATQCLKHP WLNNIFEKAK SSNIVLKSQV 540

LLKKYMARRL WKKVA 555

Nucleotide Sequence
(FASTA)

ATGCCACCAA CCCAGAATCA TGTCCTGATA CCGATCAGAA CTCCAGCCAT TGCTTCCCAA 60

AAAACAGAAG CCCAAGAAAT CAGGAAAGTG CCGCCACCAA ATATTAAAGT TCCTGTAGCA 120

GCGGCTGTGA TTATTCCCAA CACAACTGGA CAGACGTGCA CTGAATCTGT GAATGTAACC 180

CCAGCAAATC ATATCTTACC CAAGACAACC GTCACTCCTG CAGCGCCACC ATTAGTAAAC 240

AACAATACCC CCAAACTCAC TGTATCGGAA GTCCCTAAAG ACTTCAAACC ATCCCATAAA 300

TATCCACAAA CAAGTCTGCC ACCATCAGTA GCTGCACAGA GGTCTGAACA AACACCAGTA 360

AATATGCCTA CAACAAAAAC AACAACACCA CAAGATGCAG CATTGTTTCC TCCAACCCAC 420

AAACCACCTA AAACAGTGGG TTTAAGTGTT ACCACTGCAA CAAAAGAGGC TTCCTCCCTC 480

AGACAAGTGC ACAGCTGCCC CAATTCTTTA CAAAGATTAC AGGTCCCTGG ATTAAAGGCA 540

GATTTGGTCC ACACTGTAAC ATCAACACTG ACTAGTAAAA AAAGAGCAAC TGAAACTGTT 600

GGAGCAGCAA AGCTAACATC AGATGGAATA CAGATTAAAA TAAGTTCAGC TACAGACAAG 660

AATTCAGCAC AGACAAAGAG CTACAACCCT CCTAAACTCT GTTTTAAAGT TATAGATGAT 720

GTTTCACCTC AGCCTGCTCC TTTTGCGCAC CGGTTTGTGG CGCTGAAGTC TAGCCCTCCG 780

CCCTGTGACA CCTTCAGTAT CCACACCAGA GAAGTGCTTG GAGGTGGCCG CTTTGGTAAG 840

GTGCATAAAT GTACGGAGAC TAGAACGGGG ATGAGGCTCG CTGCCAAAAT CATCAACACA 900

AGAAATTCCA AAGAAAGAGA CATGGCACTG AATGAGATGC AGGTCATGAA CCAGCTGAGC 960

CACCCCAACA TCCTCCAGCT TTATGAGGCC TTCGAGGTCA AGAATCAAGT CGTGCTCATC 1020

CTGGAATATG TGGAGGGAGG CGAGCTGTTC GAGAGGATTG TGGATGAAAG CAGTCCGCTG 1080

ACGGAGGTGG ATGCGATGGT GTTTGTGAAG CAGATCTGTG AGGGCGTTCA GTACATGCAT 1140

CAGATGTACG TGCTTCATCT GGACCTTAAG CCAGAGAACA TCCTCCTTGT TAATCGCTCT 1200

AGCCATCAGG TGAAAATTAT CGACTTTGGA CTAGCCAGGA GATATAAACC ACGAGAGAAG 1260

CTCAAAGTTT CATTTGGAAC GCCTGAGTTT TTAGCTCCAG AGGTTGTGAA CTTTGATTTT 1320

GTCTCCTTCC CTACGGATAT GTGGACTTTG GGAGTCGTCA CTTACATGCT TTTAAGTGGC 1380

CTCTCTCCTT TTCTGGGTGA TGATGACGGC CAGACCCTCA ATAATGTGCT CATGGGGAAC 1440

TGGTACTTCG ACGAGGACGC TTTTGAGCAC GTGTCTGCTG ACGCGCGGGA CTTTGTTTCC 1500

AACCTACTGA TCAGAGAAAG AAGTGGTCGT ATGAGTGCCA CACAGTGTCT CAAACACCCA 1560

TGGCTCAACA ACATCTTTGA GAAAGCCAAA AGCAGTAACA TCGTGCTCAA GTCACAGGTT 1620

CTCCTCAAGA AATACATGGC CAGGCGATTG TGGAAGAAAG TGGCA 1665

Domain Profile

S: 3     ikeelgkGkfgvvvkavekstgkklaakivkvrkekdkeevkkEieilnqlrHekliqly  62

         + e lg G+fg+v+k++e+ tg  laaki+++r++k+++++ +E++++nql+H++++qly

Q: 269   TREVLGGGRFGKVHKCTETRTGMRLAAKIINTRNSKERDMALNEMQVMNQLSHPNILQLY  328

         5789********************************************************

S: 63    dafeskeeivlvlElveggelferiveedyeltEeevvlfvrqvlealeylHkkgivHld  122

         +afe k+++vl+lE+veggelferiv+e+  ltE + ++fv+q++e+++y+H+++++Hld

Q: 329   EAFEVKNQVVLILEYVEGGELFERIVDESSPLTEVDAMVFVKQICEGVQYMHQMYVLHLD  388

         ************************************************************

S: 123   lkpenillqskkskqiKlidFGlarklkkkeklkvlfgtpefvaPEvvnkepvslatDmW  182

         lkpenill++++s+q+K+idFGlar++k++eklkv fgtpef+aPEvvn ++vs+ tDmW

Q: 389   LKPENILLVNRSSHQVKIIDFGLARRYKPREKLKVSFGTPEFLAPEVVNFDFVSFPTDMW  448

         ************************************************************

S: 183   svGvityvLlsGlsPFlgdndeetlenvssakydfdeeafkevseeakdFiskllvkekk  242

         ++Gv+ty+LlsGlsPFlgd+d +tl+nv  +++ fde+af++vs +a+dF+s+ll++e++

Q: 449   TLGVVTYMLLSGLSPFLGDDDGQTLNNVLMGNWYFDEDAFEHVSADARDFVSNLLIRERS  508

         ************************************************************

S: 243   kRmsaeeaLkhkwl  256

          Rmsa+++Lkh+wl

Q: 509   GRMSATQCLKHPWL  522

         *************8

Domain Sequence
(FASTA)

TREVLGGGRF GKVHKCTETR TGMRLAAKII NTRNSKERDM ALNEMQVMNQ LSHPNILQLY 60

EAFEVKNQVV LILEYVEGGE LFERIVDESS PLTEVDAMVF VKQICEGVQY MHQMYVLHLD 120

LKPENILLVN RSSHQVKIID FGLARRYKPR EKLKVSFGTP EFLAPEVVNF DFVSFPTDMW 180

TLGVVTYMLL SGLSPFLGDD DGQTLNNVLM GNWYFDEDAF EHVSADARDF VSNLLIRERS 240

GRMSATQCLK HPWL 254

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Ciona intestinalis"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Nomascus leucogenys"; ?>Otolemur garnettii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013