EKS-DAR-00074

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DAR-00074

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	386.3	1.6E-115	193	474	282

Status

Unreviewed

Ensembl Protein

ENSDARP00000087820

UniProt Accession

B0UYG3;

Protein Name

Protein Synonyms/Alias

Novel protein similar to vertebrate PCTAIRE protein kinase 1 (PCTK1);

Gene Name

cdk16

Gene Synonyms/Alias

cdk16; si:dkey-31k5.1; DKEY-31K5.1-001;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDARG00000032072	ENSDARP00000122753	ENSDART00000132700
ENSDARG00000032072	ENSDARP00000119498	ENSDART00000137382
ENSDARG00000032072	ENSDARP00000087820	ENSDART00000093388

Organism

Danio rerio

Functional Description

Protein Length

524

Protein Sequence
(FASTA)

MDRMRKIKRQ LSLTLRGGNS GDKSLSETIS SQDTGAHSDS EAMPVGGSGG LRGSVRGSGG 60

SFSMHSLLQS YSSALRRPRS LGRSLSSYLN HTTRLEIVHE DVKMGSDGES DQASATSSDE 120

VHSPVRVRLR NNPGRKISTE DINKRLSLPA DIRLPDGYLE KFSLNSPLFD KPLSRRLRRV 180

SLSEIGFGKL ETYVKLDKLG EGTYATVYKG RSKLTDNLVA LKEIRLEHEE GAPCTAIREV 240

SLLKDLKHAN IVTLHDIIHT QKSLTLVFEY LDKDLKQYLD DCGNSIHMHN VKLFLFQLLR 300

GLNYCHRRKV LHRDLKPQNL LINDRGELKL ADFGLARAKS IPTKTYSNEV VTLWYRPPDI 360

LLGSTDYSTQ IDMWGVGCIF YEMSTGRPLF PGSTVEEELH FIFKLLGTPT EETWPGITSN 420

EEFISYNYPR YRADCLHNHT PRLDNDGVEL LSKLLQFEGK KRIAAEEAMR HPYFHCLGER 480

LLTLPDTTSI FALQEIQLEK EPGMRTNSLS ESVNSISQRQ SLLF 524

Nucleotide Sequence
(FASTA)

ATGGACCGCA TGAGGAAGAT CAAACGGCAG CTGTCCCTGA CGCTGCGGGG GGGTAACAGC 60

GGGGACAAGA GCTTGAGCGA GACCATCAGC TCTCAGGACA CAGGAGCCCA CAGCGATTCC 120

GAGGCCATGC CAGTTGGCGG CAGTGGTGGT CTGCGGGGTT CAGTGAGAGG TTCGGGGGGC 180

TCCTTCAGCA TGCACTCCCT CCTGCAGTCC TACAGCAGCG CCCTGCGCAG ACCACGCAGC 240

CTGGGCCGCA GTCTCAGCTC CTATCTCAAC CACACAACGC GCCTCGAAAT CGTCCATGAG 300

GATGTAAAAA TGGGTTCAGA CGGAGAGAGC GATCAGGCTT CGGCCACGTC CTCCGATGAG 360

GTGCACAGTC CCGTCCGAGT TCGTCTGAGA AACAACCCCG GTCGCAAAAT TTCCACAGAG 420

GACATAAACA AGCGTCTTTC TCTGCCTGCC GATATCAGGC TTCCTGATGG CTACCTGGAG 480

AAATTCAGCC TCAACAGCCC TCTGTTTGAC AAACCGCTCA GCCGGAGATT ACGCCGAGTA 540

TCGCTGTCTG AGATCGGATT TGGGAAGCTG GAGACGTACG TGAAACTGGA TAAACTAGGA 600

GAGGGCACCT ACGCTACAGT ATACAAGGGC CGCAGTAAGC TGACCGATAA CCTGGTGGCT 660

CTGAAGGAGA TCCGTTTGGA GCACGAGGAA GGAGCTCCAT GCACTGCCAT TAGAGAAGTG 720

TCTCTACTGA AGGACCTGAA ACACGCCAAT ATTGTGACTC TTCATGACAT CATCCACACT 780

CAGAAGTCTC TTACGCTTGT GTTTGAGTAC TTGGATAAAG ATCTTAAGCA GTACCTTGAT 840

GACTGTGGAA ACAGCATTCA TATGCACAAT GTTAAGCTCT TCCTGTTTCA GCTGTTGCGG 900

GGTCTAAACT ACTGTCACAG ACGTAAAGTC CTTCACCGAG ACCTCAAGCC CCAAAATCTT 960

CTGATCAACG ACCGCGGGGA GCTGAAGCTG GCTGACTTTG GTTTGGCACG AGCAAAGTCG 1020

ATTCCTACGA AGACTTACTC CAATGAGGTT GTGACCCTTT GGTATCGTCC GCCTGATATC 1080

TTGCTGGGCA GTACAGACTA TTCCACACAG ATTGACATGT GGGGTGTTGG CTGTATCTTC 1140

TACGAGATGT CTACAGGTCG ACCCTTGTTC CCCGGCTCTA CAGTGGAGGA GGAGCTGCAC 1200

TTTATCTTTA AACTGCTCGG TACGCCCACA GAGGAGACCT GGCCCGGAAT AACCTCCAAT 1260

GAGGAATTCA TCTCCTATAA CTACCCACGA TACCGTGCAG ACTGTCTCCA CAACCACACT 1320

CCACGGCTGG ACAATGATGG AGTTGAACTT CTGTCAAAAC TGCTGCAGTT TGAGGGGAAG 1380

AAACGGATCG CAGCAGAGGA AGCCATGAGA CACCCATACT TCCACTGCCT GGGAGAGAGA 1440

CTTCTCACAC TGCCAGACAC TACATCAATA TTTGCACTTC AAGAAATTCA GCTGGAGAAG 1500

GAGCCAGGAA TGAGGACGAA CTCTTTGTCA GAATCAGTCA ACAGCATATC TCAGCGACAG 1560

AGTCTGCTCT TCTGA 1575

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y kl+k+geGty++vyk+++k t+++vAlK+irle+e eg p+ta+rE+sllk+lkh+ni

Q: 193   YVKLDKLGEGTYATVYKGRSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANI  251

         7899********************************9.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v+L+++++ ++k+l+Lvfe+l++dLk++l+++ + ++++++vk +l+qll+gl+y+H++k

Q: 252   VTLHDIIH-TQKSLTLVFEYLDKDLKQYLDDCGN-SIHMHNVKLFLFQLLRGLNYCHRRK  309

         ********.99***********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         +lHRDlKpqNlLi+++g+lklaDfGlara s p+kty++evvTlwYr+P++Llg+++Yst

Q: 310   VLHRDLKPQNLLINDRGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYST  369

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ksfp  239

         ++D+W+vgci+ e+ t +plf+g++  ++l+ ifkllgtp+e++wp++++ +e+  +++p

Q: 370   QIDMWGVGCIFYEMSTGRPLFPGSTVEEELHFIFKLLGTPTEETWPGITSNEEFIsYNYP  429

         *****************************************************99799**

S: 240   kkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         ++++  l++++++l++++++ll+kll+++ kkRi a+ea++h+yf

Q: 430   RYRADCLHNHTPRLDNDGVELLSKLLQFEGKKRIAAEEAMRHPYF  474

         ********************************************9

Domain Sequence
(FASTA)

YVKLDKLGEG TYATVYKGRS KLTDNLVALK EIRLEHEEGA PCTAIREVSL LKDLKHANIV 60

TLHDIIHTQK SLTLVFEYLD KDLKQYLDDC GNSIHMHNVK LFLFQLLRGL NYCHRRKVLH 120

RDLKPQNLLI NDRGELKLAD FGLARAKSIP TKTYSNEVVT LWYRPPDILL GSTDYSTQID 180

MWGVGCIFYE MSTGRPLFPG STVEEELHFI FKLLGTPTEE TWPGITSNEE FISYNYPRYR 240

ADCLHNHTPR LDNDGVELLS KLLQFEGKKR IAAEEAMRHP YF 282

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

dre:559750

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013