EPS-DAR-00047

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-DAR-00047

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	273.0	6.3E-81	23	296	274

Status

Unreviewed

Ensembl Protein

ENSDARP00000070999

UniProt Accession

F1R5N8;

Protein Name

Protein Synonyms/Alias

Gene Name

ppm1aa

Gene Synonyms/Alias

ppm1aa;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDARG00000032155	ENSDARP00000107694	ENSDART00000126658
ENSDARG00000032155	ENSDARP00000105749	ENSDART00000127843
ENSDARG00000032155	ENSDARP00000070999	ENSDART00000076527

Organism

Danio rerio

Functional Description

Protein Length

384

Protein Sequence
(FASTA)

MGAFLDKPKM EKHNAHGDGN SLRYGLSSMQ GWRVEMEDAH TAVIGLPNSL DLWSFFAVYD 60

GHAGSQVARY CCEHLLEHIT SNPDFQGGGG GGGPAVEPSV DSVKSGIRTG FLQIDDHMRQ 120

ISEKKHGGAD RSGSTAVGVM ISPRHIYFIN CGDSRGLLSR GGAVHFFTQD HKPSNPLEKE 180

RIQNAGGSVM IQRVNGSLAV SRALGDFDYK CVHGKGPTEQ LVSPEPEVCA IERSEAEDEF 240

IVLACDGIWD VMANEELCDF VRSRLEVTDD LERVCNEIVD TCLYKGSRDN MSVVLVCFVS 300

APKVSPEAVK REAELDKYLE SRVEEILKRQ GDEGVPDLVH VMRTLASESI PNLPPGGELA 360

SKRSVIEAVY NKLNPYRNED TVLL 384

Nucleotide Sequence
(FASTA)

ATGGGTGCAT TTCTGGATAA GCCAAAGATG GAGAAACATA ACGCTCATGG GGATGGGAAC 60

AGTCTTCGCT ACGGCCTGAG CAGCATGCAG GGCTGGCGTG TTGAGATGGA AGATGCGCAC 120

ACCGCTGTCA TCGGCCTGCC CAACAGTCTG GACCTCTGGT CGTTCTTTGC CGTTTATGAT 180

GGTCACGCGG GATCACAGGT GGCACGTTAC TGCTGCGAGC ACCTTCTGGA GCACATCACC 240

AGCAACCCTG ACTTCCAGGG TGGAGGCGGA GGAGGGGGAC CAGCTGTGGA GCCCAGTGTG 300

GACAGCGTGA AGTCGGGAAT TCGCACTGGT TTCCTTCAGA TCGACGATCA CATGCGACAG 360

ATTTCGGAAA AGAAGCATGG TGGAGCTGAC CGCAGCGGCT CGACAGCTGT CGGAGTGATG 420

ATTTCACCTC GCCATATCTA CTTTATCAAC TGCGGAGATT CGCGCGGGTT GCTGAGTCGC 480

GGAGGGGCGG TGCACTTCTT CACACAGGAC CACAAACCCA GCAACCCTCT CGAGAAGGAA 540

AGGATCCAGA ACGCTGGAGG GTCTGTGATG ATCCAACGTG TCAATGGGTC TCTGGCGGTG 600

TCCAGGGCTC TGGGGGACTT TGACTATAAG TGTGTGCATG GTAAGGGTCC CACGGAGCAG 660

CTGGTGTCAC CAGAGCCCGA GGTCTGTGCT ATCGAGCGGT CAGAGGCGGA GGACGAGTTT 720

ATTGTTCTTG CTTGTGATGG GATCTGGGAT GTGATGGCCA ACGAGGAGTT GTGTGATTTT 780

GTTCGTTCAC GACTTGAGGT GACAGACGAT CTGGAGAGGG TCTGCAATGA GATTGTAGAT 840

ACCTGCTTGT ACAAGGGAAG TCGTGACAAC ATGAGTGTTG TGCTGGTGTG TTTCGTCAGT 900

GCACCGAAGG TTTCCCCTGA AGCTGTTAAA AGGGAAGCTG AGCTTGATAA ATACCTAGAG 960

AGCCGAGTAG AAGAGATCCT GAAGAGGCAG GGAGACGAAG GTGTGCCCGA CCTGGTACAT 1020

GTGATGCGCA CGTTAGCATC TGAGAGCATC CCAAACCTAC CCCCTGGAGG AGAACTGGCC 1080

AGCAAGCGGA GTGTAATTGA AGCAGTATAC AACAAACTCA ACCCATACAG GAACGAGGAT 1140

ACAGTGCTAC TTTGA 1155

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g++s++g+r emeda+t+   ++  p++ d ++ff+vyDGh+gs+va++c e+l e++

Q: 23    RYGLSSMQGWRVEMEDAHTA---VIGLPNSLDLWSFFAVYDGHAGSQVARYCCEHLLEHI  79

         69****************97...5666667778***************************

S: 62    aeele..........sseseerkvkkalakaFlstdeel.kvleeksldidksGstavva  110

         + + +          + e++ + vk+ ++++Fl++d ++ ++ e+k+   d+sGstav +

Q: 80    TSNPDfqgggggggpAVEPSVDSVKSGIRTGFLQIDDHMrQISEKKHGGADRSGSTAVGV  139

         ***99**********9***********************5555556667778********

S: 111   likdsklyvanvGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlG  170

         +i++ ++y++n+GdSr +L+r+g ++  ++dHkps++ E+eRi++aggsv+ +   Rv+G

Q: 140   MISPRHIYFINCGDSRGLLSRGGAVHFFTQDHKPSNPLEKERIQNAGGSVMIQ---RVNG  196

         *****************************************************...****

S: 171   vLavsRalGdlylk.........pyvtpePevtshrl.tsedefliLasDGlwdvvsnee  220

         +LavsRalGd+++k         ++v+pePev  +++ + edef++La+DG+wdv+ nee

Q: 197   SLAVSRALGDFDYKcvhgkgpteQLVSPEPEVCAIERsEAEDEFIVLACDGIWDVMANEE  256

         *************************************555677*****************

S: 221   avslvrdvlekkeaeqeaakkLvklalargskdnvsaivv  260

         ++++vr++le +++++ +++++v+++l +gs+dn+s+++v

Q: 257   LCDFVRSRLEVTDDLERVCNEIVDTCLYKGSRDNMSVVLV  296

         ***********************************99875

Domain Sequence
(FASTA)

RYGLSSMQGW RVEMEDAHTA VIGLPNSLDL WSFFAVYDGH AGSQVARYCC EHLLEHITSN 60

PDFQGGGGGG GPAVEPSVDS VKSGIRTGFL QIDDHMRQIS EKKHGGADRS GSTAVGVMIS 120

PRHIYFINCG DSRGLLSRGG AVHFFTQDHK PSNPLEKERI QNAGGSVMIQ RVNGSLAVSR 180

ALGDFDYKCV HGKGPTEQLV SPEPEVCAIE RSEAEDEFIV LACDGIWDVM ANEELCDFVR 240

SRLEVTDDLE RVCNEIVDTC LYKGSRDNMS VVLV 274

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0000287	; F:magnesium ion binding
GO:0030145	; F:manganese ion binding
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0006470	; P:protein dephosphorylation

KEGG

InterPros

IPR001932	; PP2C-like.
IPR012911	; PP2C_C.
IPR000222	; PP2C_Mn2_Asp60_BS.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481	; PP2C; 1.
PF07830	; PP2C_C; 1.

SMARTs

SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

PS01032

; PP2C; 1.

Prints

Created Date

20-Feb-2013