EKS-DAR-00681

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DAR-00681

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	325.2	6.2E-97	17	291	275

Status

Unreviewed

Ensembl Protein

ENSDARP00000047072

UniProt Accession

A5PLJ7;

Protein Name

Protein Synonyms/Alias

Novel protein similar to vertebrate oxidative-stress responsive 1 (OXSR1); Oxsr1a protein;

Gene Name

oxsr1a

Gene Synonyms/Alias

oxsr1a; DKEY-24C2.5-001;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDARG00000034189	ENSDARP00000047072	ENSDART00000047073

Organism

Danio rerio

Functional Description

Protein Length

515

Protein Sequence
(FASTA)

MSEDPSSQPW SIDKDDYELQ EVIGSGATAV VQAAYCKPRK EKVAIKRINL EKCQTSMDEL 60

LKEIQAMSQC HHPNIVSYYT SFVVKDELWL VMKLLSGGSV LDFIKYIISK GEHKSGVMDE 120

PSIATILREV LEGLEYLHKN GQIHRDVKAG NILLGEDGSV QIADFGVSAF LATGGDMTRN 180

KVRKTFVGTP CWMAPEVMEQ VRGYDFKADL WSFGITAIEL ATGAAPYHKY PPMKVLMLTL 240

QNDPPCLETG VTDKEMVKKY GKSFRKMISL CLQKDPEKRP TAAELLKHKF FTKAKNTDYL 300

KEKLLERAPT IGERSRKVRR VPGSSGRLHK TEDGEWEWSD DELDVESEEG KAAVAALRSP 360

RVKEEAVPNA EVFPAESSGF LQPAAVGQPE VPHAADDTAT ISASQAVAGP TTTGQDSAKI 420

PISLVLRLRN TKKELNDIRF EFMPGRDTAD GVSQELVSAG LVDGRDLVIV AANLQKIVDD 480

PQTHKNVTFK LASGVDSSEI PDDVKLMGFA QLSIS 515

Nucleotide Sequence
(FASTA)

ATGTCCGAGG ACCCGAGCTC TCAACCTTGG TCCATCGACA AGGATGACTA TGAGCTACAG 60

GAGGTGATCG GGAGTGGAGC CACAGCTGTG GTCCAGGCAG CGTATTGCAA ACCCAGGAAG 120

GAGAAGGTGG CCATTAAACG CATCAATCTT GAGAAATGCC AGACCAGCAT GGATGAGCTC 180

CTGAAAGAGA TCCAGGCAAT GAGCCAGTGC CATCACCCAA ATATTGTGTC TTATTACACG 240

TCCTTTGTGG TCAAGGATGA GCTTTGGCTG GTCATGAAGT TGCTCAGTGG CGGCTCAGTG 300

CTTGATTTTA TTAAGTACAT CATTTCCAAA GGAGAGCATA AATCGGGCGT GATGGACGAG 360

CCCAGCATTG CCACCATACT AAGAGAGGTG CTCGAAGGTC TCGAATATCT GCACAAAAAT 420

GGCCAGATTC ACAGGGATGT GAAGGCTGGA AATATTCTTT TAGGAGAGGA CGGCTCTGTT 480

CAGATTGCAG ACTTTGGTGT TAGTGCCTTT TTAGCGACTG GTGGAGACAT GACTCGAAAC 540

AAAGTGAGGA AGACATTTGT AGGAACTCCA TGCTGGATGG CTCCTGAGGT CATGGAGCAG 600

GTTAGGGGTT ATGATTTCAA AGCTGATTTA TGGAGCTTTG GGATTACGGC GATTGAGCTG 660

GCAACCGGAG CTGCTCCATA TCACAAATAT CCTCCGATGA AGGTTCTCAT GTTAACCCTG 720

CAGAATGACC CTCCGTGTTT AGAGACTGGA GTTACAGACA AAGAGATGGT TAAAAAGTAT 780

GGTAAATCTT TCCGGAAGAT GATCTCTTTG TGCCTCCAGA AGGATCCAGA AAAACGGCCT 840

ACAGCTGCTG AACTCTTGAA ACACAAGTTC TTCACAAAAG CCAAGAACAC TGATTACTTG 900

AAAGAAAAAC TGCTGGAGAG GGCACCTACA ATAGGAGAGA GATCAAGGAA GGTGCGGAGG 960

GTCCCGGGCT CCAGCGGTCG GCTCCACAAG ACTGAGGACG GAGAGTGGGA ATGGAGTGAT 1020

GATGAGCTGG ATGTGGAGAG TGAGGAAGGA AAGGCAGCAG TGGCTGCTTT ACGGTCACCA 1080

AGAGTAAAGG AGGAGGCGGT GCCGAATGCG GAGGTTTTTC CAGCTGAATC GTCTGGTTTC 1140

CTGCAGCCAG CAGCTGTAGG TCAGCCTGAA GTGCCACACG CTGCAGATGA CACGGCCACG 1200

ATATCAGCCT CTCAGGCTGT TGCTGGACCA ACTACGACGG GGCAGGACTC AGCTAAAATC 1260

CCTATTAGCC TGGTCCTTAG ATTGAGGAAT ACAAAGAAAG AGCTGAACGA TATCAGATTT 1320

GAGTTCATGC CAGGGAGAGA CACAGCAGAT GGAGTGTCTC AGGAGCTTGT GTCTGCTGGA 1380

CTGGTGGATG GGAGAGATCT AGTCATTGTT GCAGCCAACT TACAGAAAAT TGTTGATGAT 1440

CCACAAACTC ACAAAAATGT CACTTTCAAG CTGGCATCAG GAGTGGACAG CTCTGAAATT 1500

CCAGACGATG TTAAACTCAT GGGATTTGCT CAGCTGAGTA TAAGTTAA 1548

Domain Profile

S: 1     yelleeigkGalgkvylarekktgelvaikkinlekq.ekleelqkeisvlkklkhpniv  59

         yel+e+ig+Ga++ v++a++k+++e+vaik+inlek+ ++++el kei+++++++hpniv

Q: 17    YELQEVIGSGATAVVQAAYCKPRKEKVAIKRINLEKCqTSMDELLKEIQAMSQCHHPNIV  76

         99***********************************8899*******************

S: 60    eylesflkeeelwlvmeylagGslsdlvk......eelkselkEeqiayilrevlkaLey  113

         +y++sf++++elwlvm++l+gGs+ d +k      e+++  ++E +ia+ilrevl++Ley

Q: 77    SYYTSFVVKDELWLVMKLLSGGSVLDFIKyiiskgEHKSGVMDEPSIATILREVLEGLEY  136

         ********************************9999999*********************

S: 114   lHskkviHrdikakniLlteegeVkLsdfgvaaqlek....trkk.rktvvgtpywmAPE  168

         lH++++iHrd+ka+niLl e+g+V+++dfgv+a l++    tr+k rkt+vgtp+wmAPE

Q: 137   LHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATggdmTRNKvRKTFVGTPCWMAPE  196

         ***********************************98888888889**************

S: 169   viaqeekgYdekaDiwslGItaielaegepPfkdleplkallkilkneppklksk.....  223

         v++q  +gYd kaD+ws+GItaiela+g++P+++++p+k+l+++l+n+pp l++

Q: 197   VMEQ-VRGYDFKADLWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPCLETGvtdke  255

         ***5.9********************************************9966666677

S: 224   ..kkfskefkefvekclqknpekRpsasellkhkFl  257

           kk++k+f+++++ clqk+pekRp+a+ellkhkF+

Q: 256   mvKKYGKSFRKMISLCLQKDPEKRPTAAELLKHKFF  291

         7799*******************************7

Domain Sequence
(FASTA)

YELQEVIGSG ATAVVQAAYC KPRKEKVAIK RINLEKCQTS MDELLKEIQA MSQCHHPNIV 60

SYYTSFVVKD ELWLVMKLLS GGSVLDFIKY IISKGEHKSG VMDEPSIATI LREVLEGLEY 120

LHKNGQIHRD VKAGNILLGE DGSVQIADFG VSAFLATGGD MTRNKVRKTF VGTPCWMAPE 180

VMEQVRGYDF KADLWSFGIT AIELATGAAP YHKYPPMKVL MLTLQNDPPC LETGVTDKEM 240

VKKYGKSFRK MISLCLQKDP EKRPTAAELL KHKFF 275

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Caenorhabditis elegans"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Drosophila melanogaster"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mustela putorius furo"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Petromyzon marinus"; ?>Procavia capensis"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity

KEGG

dre:568602

;

InterPros

IPR011009	; Kinase-like_dom.
IPR024678	; Kinase_OSR1/WNK_CCT.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF12202	; OSR1_C; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013