EKS-DAR-00825

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DAR-00825

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/Aur	451.5	1.3E-135	53	303	251

Status

Unreviewed

Ensembl Protein

ENSDARP00000054822

UniProt Accession

F1RDC1;

Protein Name

Protein Synonyms/Alias

Aurora kinase B;

Gene Name

aurkb

Gene Synonyms/Alias

aurkb;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDARG00000037640	ENSDARP00000054822	ENSDART00000054823

Organism

Danio rerio

Functional Description

Protein Length

320

Protein Sequence
(FASTA)

MQNKENREPK VQQTPSAGVG PLRVEMNPDT HAVSGPGRVP VKSNSKVLSI DDFDIGRPLG 60

KGKFGNVYLA RERKLKVVIA LKVLFKSQMV KEGVEHQLRR EIEIQSHLRH PNILRFYNYF 120

HDDTRVFLIL EYAPRGEMYK ELQRYGRFDD QRTATYMEEV SDALQYCHEK KVIHRDIKPE 180

NLLLGYRGEL KIADFGWSVH APSLRRRTMC GTLDYLPPEM IEGHSHDEKV DLWSIGVLCY 240

ECLVGNPPFE TASHAETYKR ITKVDLQFPK LVSEGARDLI SKLLRHSPSM RLPLRSVMEH 300

PWVKANSRRV LPPVCSSEPH 320

Nucleotide Sequence
(FASTA)

ATGCAGAATA AAGAAAACCG GGAACCCAAA GTTCAACAAA CACCGTCTGC TGGTGTGGGT 60

CCGCTCAGAG TTGAGATGAA TCCAGACACA CACGCAGTCT CAGGTCCTGG CAGAGTTCCT 120

GTCAAGTCAA ACTCCAAAGT GCTGTCCATC GATGACTTTG ACATTGGCCG TCCTCTGGGA 180

AAGGGTAAAT TCGGGAACGT GTATCTGGCG CGCGAGCGGA AGCTGAAGGT GGTGATCGCG 240

CTGAAGGTGC TCTTCAAGTC TCAGATGGTA AAAGAGGGAG TGGAGCATCA GCTGCGCAGG 300

GAGATCGAGA TACAGTCACA CCTCAGGCAT CCCAACATCC TTCGCTTCTA CAACTACTTC 360

CATGACGACA CCCGTGTGTT TCTGATTTTG GAGTATGCGC CGCGTGGTGA GATGTACAAA 420

GAGCTTCAGC GATACGGACG CTTTGACGAT CAGCGCACTG CTACTTACAT GGAGGAGGTG 480

TCGGACGCGC TGCAGTACTG CCATGAGAAG AAGGTGATCC ACAGAGACAT TAAACCAGAA 540

AACCTGCTGC TGGGATACAG AGGAGAACTG AAGATCGCAG ACTTCGGCTG GTCTGTGCAC 600

GCGCCCTCAC TCAGACGGCG GACGATGTGC GGTACGCTGG ATTACCTGCC GCCAGAGATG 660

ATCGAGGGCC ACAGTCACGA TGAGAAGGTG GATCTGTGGT CCATCGGTGT GCTGTGCTAC 720

GAGTGTTTAG TGGGAAACCC TCCATTCGAG ACCGCCAGCC ACGCCGAGAC ATACAAGCGC 780

ATCACTAAGG TGGATCTGCA GTTCCCGAAG CTGGTGTCTG AGGGCGCGCG GGACCTGATC 840

TCCAAGCTGC TGCGCCACAG TCCCTCCATG CGCCTGCCGC TGCGCAGTGT GATGGAGCAC 900

CCGTGGGTGA AGGCCAACTC CCGCAGGGTG CTGCCGCCCG TCTGCAGCTC CGAGCCACAC 960

TGA 963

Domain Profile

S: 1     feiGrklGkGkfGnvylarekkskfivalkvlfkeqlekegvekqlrreieiqshlkhpn  60

         f+iGr+lGkGkfGnvylare+k k ++alkvlfk+q+ kegve+qlrreieiqshl+hpn

Q: 53    FDIGRPLGKGKFGNVYLARERKLKVVIALKVLFKSQMVKEGVEHQLRREIEIQSHLRHPN  112

         9***********************************************************

S: 61    ilrlygyfhdekrvylileyaprGelykelqkskkldeqraakyieeladalsylhkkkv  120

         ilr y+yfhd++rv+lileyaprGe+ykelq+  ++d+qr+a+y+ee++dal+y+h+kkv

Q: 113   ILRFYNYFHDDTRVFLILEYAPRGEMYKELQRYGRFDDQRTATYMEEVSDALQYCHEKKV  172

         ************************************************************

S: 121   ihrdikpenlllgskgelkladfGwsvhapsskrktlcGtldylppemvegreydekvdl  180

         ihrdikpenlllg++gelk+adfGwsvhaps +r+t+cGtldylppem+eg+++dekvdl

Q: 173   IHRDIKPENLLLGYRGELKIADFGWSVHAPSLRRRTMCGTLDYLPPEMIEGHSHDEKVDL  232

         ************************************************************

S: 181   walGvlcyellvGkppfeseskdetykrikkvdlklpssvskgakdliskllkkepkerl  240

         w++Gvlcye lvG+ppfe++s+ etykri+kvdl++p+ vs+ga+dliskll++ p+ rl

Q: 233   WSIGVLCYECLVGNPPFETASHAETYKRITKVDLQFPKLVSEGARDLISKLLRHSPSMRL  292

         ************************************************************

S: 241   tladvlahpwi  251

         +l+ v++hpw+

Q: 293   PLRSVMEHPWV  303

         **********8

Domain Sequence
(FASTA)

FDIGRPLGKG KFGNVYLARE RKLKVVIALK VLFKSQMVKE GVEHQLRREI EIQSHLRHPN 60

ILRFYNYFHD DTRVFLILEY APRGEMYKEL QRYGRFDDQR TATYMEEVSD ALQYCHEKKV 120

IHRDIKPENL LLGYRGELKI ADFGWSVHAP SLRRRTMCGT LDYLPPEMIE GHSHDEKVDL 180

WSIGVLCYEC LVGNPPFETA SHAETYKRIT KVDLQFPKLV SEGARDLISK LLRHSPSMRL 240

PLRSVMEHPW V 251

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Dasypus novemcinctus"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013