| Tag | Content |
|---|
| EKPD ID | EPS-DAR-00020 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| DSP/aDSP | 138.1 | 3.9E-40 | 5 | 139 | 135 |
|
| Status | Reviewed |
| Ensembl Protein | ENSDARP00000058288 |
| UniProt Accession | Q566R7; A8B8L3; |
| Protein Name | Dual specificity protein phosphatase 22-B |
| Protein Synonyms/Alias | |
| Gene Name | dusp22b |
| Gene Synonyms/Alias | dusp22b; dusp22; si:ch73-170d1.1, zgc:112536; |
| Ensembl Information | |
| Organism | Danio rerio |
| Functional Description | Activates the Jnk signaling pathway. Dephosphorylatesand deactivates p38 and stress-activated protein kinase/c-Jun N- terminal kinase (SAPK/JNK) (By similarity). |
| Protein Length | 183 |
Protein Sequence
(FASTA) | | MGNGINKVLP DLYLGNFKDA RDREQLARNN ITHILSIHDT AAPILQEMTY LCIAAADSPT 60 | | QNLIQHFRQS IAFIHQSRLK GEGCLVHCLA GVSRSVTLVV AYIMTVTTLG WQEALAAVKI 120 | | ARPCASPNTG FQNQLQEFQT GELQQFREWL KEEYKENPFN DEEDIRNLLT KASTEEDAEL 180 | | QNN 183 |
|
Nucleotide Sequence
(FASTA) | | ATGGGAAACG GCATTAATAA GGTTCTGCCT GACCTGTACT TGGGTAATTT CAAAGATGCC 60 | | AGAGATCGTG AGCAGTTGGC CAGAAACAAC ATCACACACA TCCTCTCCAT CCACGATACT 120 | | GCAGCGCCCA TATTACAGGA GATGACTTAT CTGTGTATCG CAGCAGCAGA TTCGCCCACA 180 | | CAGAACCTCA TCCAGCACTT TAGGCAGAGC ATTGCGTTCA TTCACCAATC TCGACTGAAA 240 | | GGGGAAGGCT GTCTAGTTCA CTGTTTGGCA GGAGTTTCCC GTAGCGTGAC GCTGGTGGTG 300 | | GCCTACATCA TGACCGTCAC CACGCTGGGC TGGCAGGAGG CTCTGGCTGC GGTGAAGATA 360 | | GCGAGACCTT GTGCTTCACC AAACACCGGC TTCCAGAACC AACTGCAGGA GTTTCAGACT 420 | | GGAGAACTAC AGCAGTTCAG AGAGTGGCTG AAGGAGGAGT ACAAGGAAAA CCCTTTTAAT 480 | | GATGAGGAGG ACATTCGCAA TTTGCTGACA AAAGCATCGA CGGAGGAGGA CGCAGAGCTG 540 | | CAGAACAACT AA 552 |
|
| Domain Profile | S: 2 vteilpglylgdqataldrreLsklgitvvinaslsvikvqviPeylikkgityknipvd 61 | ++++lp+lylg+ ++a dr +L +++it+++ + i +++ty+ i + | Q: 5 INKVLPDLYLGNFKDARDREQLARNNITHILSIHDTAAP--------ILQEMTYLCIAAA 56 | 799*******************88888887765444444........66899******** |
| S: 62 DsdvtdllqyfdeaaefideakekggkvlvHCaaGvsRSatlvlaYLmkveglslsdAie 121 | Ds++++l+q+f++ ++fi++ + kg+ +lvHC aGvsRS+tlv+aY+m+v+ l +++A+ | Q: 57 DSPTQNLIQHFRQSIAFIHQSRLKGEGCLVHCLAGVSRSVTLVVAYIMTVTTLGWQEALA 116 | ************************************************************ |
| S: 122 avkrkrpsiepnegfleQLlele 144 | avk rp+++pn gf +QL e++ | Q: 117 AVKIARPCASPNTGFQNQLQEFQ 139 | ********************997 |
|
Domain Sequence
(FASTA) | | INKVLPDLYL GNFKDARDRE QLARNNITHI LSIHDTAAPI LQEMTYLCIA AADSPTQNLI 60 | | QHFRQSIAFI HQSRLKGEGC LVHCLAGVSR SVTLVVAYIM TVTTLGWQEA LAAVKIARPC 120 | | ASPNTGFQNQ LQEFQ 135 |
|
| Keyword | Complete proteome; Cytoplasm; Hydrolase; Nucleus; Protein phosphatase; Reference proteome. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | |
| KEGG | |
| InterPros | |
| Pfam | |
| SMARTs | |
| Prosites | |
| Prints | |
| Created Date | 20-Feb-2013 |