EKS-DAR-00623

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DAR-00623

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	400.8	6.9E-120	195	482	288

Status

Unreviewed

Ensembl Protein

ENSDARP00000060865

UniProt Accession

F1R709;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC100331938

Gene Synonyms/Alias

LOC100331938;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDARG00000041516	ENSDARP00000060865	ENSDART00000060866

Organism

Danio rerio

Functional Description

Protein Length

519

Protein Sequence
(FASTA)

TIAFVLNIEM HILFYLCLPL SGVSHAEVAT RECVYYNDNW RTEKTNQSGF ERCEGEKDKR 60

LHCYASWLNS TGTIRLVKKG CWLDDFNCYD SRQECVATEE SPQVFFCCCE GNYCNEKFTH 120

LPEAIAPAVK IQPPQPGPSL FGILVYSLLP LAILSLALVL ACWTYHQRKP PYRHVDIGQD 180

AGLPPPSPLV GLKPLQLLEL KARGRFGCVW KAQLLSEYVA VKIFPIQDKQ SWQNERDIYL 240

TEGFKHENIL HYISAEKRGT NLQMELWLVT EFHERGSLTD YLKGNVVSWP QLCHISASMS 300

RGLAYLHEDL PYRAEGPKPA IAHRDFKSKN VLLKMDLTAV IADFGLAVRF EPGKPPGDTH 360

GQVGTRRYMA PEVLEGAINF QRDSFLRIDM YALGLVLWEL VSRCTASDGP VGEYQLPFEE 420

EVGQHPSLED LQDAVVHKKM RPVFKDCWVK HQGLSQLCET IEECWDHDAE ARLSAGCVEE 480

RISTISKSNN TLNTSTSECL LSMLTSHSDT DLPPKDSST 519

Nucleotide Sequence
(FASTA)

ACAATTGCTT TTGTATTAAA TATTGAAATG CATATTTTAT TTTATCTCTG TCTTCCTCTT 60

TCAGGAGTCA GTCATGCGGA AGTGGCGACT AGAGAGTGTG TCTATTATAA CGATAACTGG 120

CGGACGGAGA AAACCAATCA GAGCGGGTTC GAGAGGTGCG AGGGGGAGAA AGATAAGAGG 180

CTTCACTGTT ACGCGTCATG GCTGAACTCC ACCGGCACCA TCCGCCTGGT CAAGAAGGGC 240

TGCTGGCTCG ACGACTTCAA CTGCTATGAC AGCAGACAGG AGTGTGTGGC CACAGAGGAG 300

AGTCCGCAGG TGTTCTTCTG CTGCTGTGAA GGGAACTATT GCAACGAGAA GTTCACACAC 360

CTGCCGGAAG CCATCGCCCC TGCAGTGAAG ATCCAGCCTC CACAGCCGGG TCCGTCTCTT 420

TTTGGCATCC TGGTTTATTC TCTTCTTCCT CTGGCCATTC TCTCTTTGGC CCTGGTGCTC 480

GCTTGCTGGA CGTACCACCA GCGAAAACCA CCATACAGAC ACGTCGACAT CGGACAGGAT 540

GCTGGTCTTC CTCCACCGTC TCCTCTGGTT GGACTGAAGC CTCTGCAGCT GCTGGAACTG 600

AAAGCTCGTG GTCGCTTTGG CTGTGTGTGG AAGGCCCAAC TATTGAGCGA ATATGTGGCT 660

GTCAAAATAT TTCCCATACA GGACAAGCAG TCATGGCAGA ACGAAAGAGA CATTTACCTC 720

ACAGAGGGTT TTAAACACGA GAATATTCTG CACTACATCT CGGCAGAGAA ACGAGGCACC 780

AACCTTCAGA TGGAGCTGTG GCTGGTCACA GAGTTCCACG AAAGGGGTTC GCTGACAGAT 840

TACCTGAAGG GGAACGTGGT GAGCTGGCCG CAGCTGTGCC ATATTTCGGC AAGCATGTCC 900

CGAGGTCTGG CGTATCTTCA TGAAGACCTT CCTTATCGTG CTGAGGGACC CAAACCAGCC 960

ATTGCACACA GGGATTTTAA GAGTAAGAAC GTGCTGCTAA AGATGGATTT AACAGCAGTG 1020

ATTGCAGACT TCGGGTTGGC GGTGCGCTTT GAGCCTGGGA AACCACCTGG AGATACACAC 1080

GGCCAGGTGG GAACGCGGCG TTATATGGCT CCAGAGGTGC TGGAAGGAGC CATTAACTTC 1140

CAGAGGGACT CTTTCCTGAG GATCGACATG TATGCTCTGG GACTGGTGCT GTGGGAGCTG 1200

GTGTCTCGCT GCACTGCTTC TGATGGTCCT GTAGGTGAGT ATCAGCTGCC GTTTGAGGAG 1260

GAGGTCGGTC AGCACCCTTC ACTGGAGGAC CTGCAGGACG CAGTGGTGCA CAAGAAGATG 1320

CGGCCCGTCT TTAAAGACTG CTGGGTCAAG CATCAGGGTT TAAGCCAGTT GTGCGAGACC 1380

ATCGAGGAGT GCTGGGACCA CGACGCTGAA GCTCGACTAT CAGCGGGCTG CGTGGAGGAG 1440

CGAATCTCCA CCATCTCCAA GTCCAACAAC ACCCTCAACA CATCTACCTC CGAGTGCCTG 1500

CTCTCCATGC TGACGTCCCA CAGCGACACA GACCTGCCGC CCAAAGACTC CAGCACCTGA 1560

Domain Profile

S: 1     lklleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfia  60

         l+llel ++Gr+g+Vwka+l  e+vAvKif+ +d++sw++E++iy t   +henil++i+

Q: 195   LQLLELKARGRFGCVWKAQLLSEYVAVKIFPIQDKQSWQNERDIYLTEGFKHENILHYIS  254

         6899********************************************************

S: 61    adkkeedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtk  120

         a+k+ +++++el+lvte+he+gsL+dyLk +++++ +l+++  s+++Gla+LHe++++

Q: 255   AEKRGTNLQMELWLVTEFHERGSLTDYLKGNVVSWPQLCHISASMSRGLAYLHEDLPYRA  314

         ************************************************************

S: 121   gkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekeeldlaansqvGtkRYmaPE  180

         +  KpaiaHRD+kskN+l+k dlt++iaD+GLa+++e  k   d  ++ qvGt+RYmaPE

Q: 315   EGPKPAIAHRDFKSKNVLLKMDLTAVIADFGLAVRFEPGKPPGD--THGQVGTRRYMAPE  372

         9****************************************888..79************

S: 181   vleealnlkdfeafkraDvYslgLvlWEvasRceevdeeveeyklpfeevvgsdPsleem  240

         vle+a+n+++ ++f r+D+Y+lgLvlWE++sRc+++d+ v ey+lpfee+vg++Psle++

Q: 373   VLEGAINFQR-DSFLRIDMYALGLVLWELVSRCTASDGPVGEYQLPFEEEVGQHPSLEDL  431

         *********9.9************************************************

S: 241   kevvvekklrPkipeawkkkealkelsklleecWdadpeaRltalrvkkrl  291

         ++ vv+kk+rP +++ w k++ l++l++++eecWd+d+eaRl+a +v++r+

Q: 432   QDAVVHKKMRPVFKDCWVKHQGLSQLCETIEECWDHDAEARLSAGCVEERI  482

         ************************************************985

Domain Sequence
(FASTA)

LQLLELKARG RFGCVWKAQL LSEYVAVKIF PIQDKQSWQN ERDIYLTEGF KHENILHYIS 60

AEKRGTNLQM ELWLVTEFHE RGSLTDYLKG NVVSWPQLCH ISASMSRGLA YLHEDLPYRA 120

EGPKPAIAHR DFKSKNVLLK MDLTAVIADF GLAVRFEPGK PPGDTHGQVG TRRYMAPEVL 180

EGAINFQRDS FLRIDMYALG LVLWELVSRC TASDGPVGEY QLPFEEEVGQ HPSLEDLQDA 240

VVHKKMRPVF KDCWVKHQGL SQLCETIEEC WDHDAEARLS AGCVEERI 288

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Caenorhabditis elegans"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Drosophila melanogaster"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Oreochromis niloticus"; ?>Oryzias latipes"; ?>Petromyzon marinus"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0017002	; F:activin-activated receptor activity
GO:0005524	; F:ATP binding
GO:0004702	; F:receptor signaling protein serine/threonine kinase activity
GO:0005024	; F:transforming growth factor beta-activated receptor activity
GO:0023014	; P:signal transduction by phosphorylation

KEGG

InterPros

IPR000333	; Activin_II/TGFBeta-II_recpt.
IPR015768	; Activin_II_recpt.
IPR000472	; Activin_rcpt.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF01064	; Activin_recp; 1.
PF00069	; Pkinase; 1.

SMARTs

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR00653

; ACTIVIN2R.

Created Date

20-Feb-2013