EKS-DAR-00662

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DAR-00662

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	355.6	3.3E-106	304	555	252

Status

Unreviewed

Ensembl Protein

ENSDARP00000006253

UniProt Accession

E7F3I9;

Protein Name

Protein Synonyms/Alias

Gene Name

CR352290.1

Gene Synonyms/Alias

CR352290.1; LOC100537683;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDARG00000042624	ENSDARP00000006253	ENSDART00000009560

Organism

Danio rerio

Functional Description

Protein Length

579

Protein Sequence
(FASTA)

MSDNGEVEDK PPAPPMRNTS TMIGSSGKDS GPLNHGSKPL PPNPEDKRRK EGFIRSILTG 60

GGDKTNKKKE RPEISLPSDF EHTIHVGFDA VTGEFTGMPE QWARLLQTSN ITKLEQKKNP 120

QAVLDVLKFY DSKETSNNQK YMSFTDKGVE NFNSSSAVVP KTVSETPAVA TVSEDEDEEE 180

DEATPPPVIA PRPEHTKSVS ASLIISPLNY SPPSEIKQIR LSPEEKILSD ILATSSLQTK 240

NRRTCNNFNY EVNTKQNFPS GAPSRDSTLT SRCVAKASGK RRRIHHLFEE LRSIVSVGDP 300

KKKYTRFEKI GQGASGTVYT AIDIATGQEV AIKQMNLQQQ PKKELIINEI LVMRENKNPN 360

IVNYLDSYLV GDELWVVMEY LAGGSLTDVV TETCMDEAQI AAVCRECLQA LEFLHCNQVI 420

HRDIKSDNIL LGMDGSVKLT DFGFCAQITP EQSKRSTMVG TPYWMAPEVV TRKAYGPKVD 480

IWSLGIMAIE MIEGEPPYLN ENPLRALYLI ATNGTPELQN PEKLSAVFRD FLNRCLEMDV 540

EKRGSAKELL QHQFLKVAKP LSSLTPLIIA AKEAAKNNR 579

Nucleotide Sequence
(FASTA)

ATGTCAGACA ATGGGGAAGT AGAGGACAAG CCGCCAGCTC CGCCCATGAG GAACACCAGC 60

ACTATGATTG GCTCGTCCGG TAAAGACTCA GGACCGCTGA ATCACGGCTC CAAACCGCTG 120

CCGCCCAATC CAGAGGACAA GAGGAGGAAA GAGGGATTCA TACGATCCAT CCTGACCGGA 180

GGAGGAGACA AGACCAATAA GAAAAAGGAG CGTCCAGAGA TCTCCCTGCC ATCAGACTTT 240

GAGCACACCA TCCATGTTGG CTTTGACGCA GTCACTGGAG AGTTCACTGG CATGCCTGAG 300

CAGTGGGCTC GATTACTCCA GACGTCCAAC ATCACCAAAC TGGAGCAGAA GAAGAATCCT 360

CAGGCCGTTC TAGACGTGCT CAAATTCTAC GACTCGAAAG AGACGTCCAA CAACCAGAAA 420

TACATGAGCT TTACAGATAA AGGTGTGGAG AACTTCAACT CCTCCAGCGC AGTGGTCCCC 480

AAAACTGTGT CTGAAACGCC CGCCGTCGCC ACCGTCTCCG AGGATGAGGA CGAGGAAGAG 540

GATGAAGCCA CGCCGCCACC CGTCATCGCC CCCCGGCCAG AACACACCAA ATCTGTGAGT 600

GCTTCCCTAA TTATTAGCCC CCTGAATTAT TCACCCCCCT CTGAAATAAA ACAAATAAGA 660

CTTTCTCCAG AAGAAAAAAT ATTATCAGAC ATACTGGCTA CATCAAGTTT GCAAACTAAG 720

AACCGGCGGA CGTGCAACAA CTTTAACTAT GAGGTAAACA CAAAACAAAA CTTTCCATCC 780

GGAGCTCCTT CACGGGACTC CACACTTACG TCACGTTGTG TTGCCAAAGC AAGTGGGAAA 840

AGAAGAAGAA TTCATCATTT GTTTGAGGAG TTGAGGAGTA TAGTCAGCGT CGGCGACCCG 900

AAAAAGAAGT ACACGCGCTT TGAGAAGATC GGCCAGGGGG CATCTGGAAC CGTCTATACA 960

GCCATAGACA TCGCCACAGG ACAAGAGGTG GCCATCAAAC AGATGAACCT GCAGCAGCAG 1020

CCCAAGAAAG AGCTGATCAT CAACGAGATC CTGGTCATGA GGGAAAACAA GAACCCAAAC 1080

ATCGTCAACT ACCTGGACAG TTATCTGGTT GGCGATGAGC TGTGGGTGGT GATGGAGTAT 1140

CTGGCTGGAG GCTCGCTGAC GGATGTGGTG ACAGAAACCT GTATGGATGA AGCACAGATC 1200

GCAGCCGTCT GTCGGGAGTG TCTGCAGGCT CTGGAGTTCC TGCACTGCAA TCAGGTGATT 1260

CACAGAGACA TCAAGAGCGA CAACATCCTG CTGGGGATGG ACGGCTCCGT CAAACTCACT 1320

GATTTCGGCT TCTGCGCTCA GATCACTCCC GAGCAGAGCA AGCGCAGCAC AATGGTCGGG 1380

ACGCCCTACT GGATGGCGCC GGAGGTCGTG ACCCGCAAGG CTTACGGGCC CAAAGTGGAC 1440

ATCTGGTCTC TGGGCATCAT GGCCATCGAG ATGATCGAGG GCGAACCGCC CTACCTCAAC 1500

GAGAACCCGC TCCGGGCTCT GTATCTGATC GCCACTAATG GGACGCCGGA GCTGCAGAAC 1560

CCAGAGAAGC TTTCTGCTGT ATTTCGGGAT TTTCTAAACC GCTGTTTGGA GATGGACGTG 1620

GAGAAAAGAG GCTCTGCCAA AGAGCTCCTA CAGCACCAGT TCCTGAAGGT GGCCAAGCCT 1680

CTGTCCAGCC TCACGCCCCT GATCATAGCG GCCAAAGAGG CAGCAAAAAA CAACCGCTAG 1740

Domain Profile

S: 1     yelleeigkGalgkvylarekktgelvaikkinlekqekleelqkeisvlkklkhpnive  60

         y+ +e+ig+Ga+g+vy+a ++ tg+ vaik++nl++q+k+e++++ei v+++ k+pniv+

Q: 304   YTRFEKIGQGASGTVYTAIDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVN  363

         7889********************************************************

S: 61    ylesflkeeelwlvmeylagGslsdlvkeelkselkEeqiayilrevlkaLeylHskkvi  120

         yl+s+l+ +elw+vmeylagGsl+d+v+   ++ ++E qia+++re+l+aLe+lH ++vi

Q: 364   YLDSYLVGDELWVVMEYLAGGSLTDVVT---ETCMDEAQIAAVCRECLQALEFLHCNQVI  420

         ****************************...9****************************

S: 121   HrdikakniLlteegeVkLsdfgvaaqlektrkkrktvvgtpywmAPEviaqeekgYdek  180

         Hrdik++niLl ++g+VkL+dfg++aq++ +++kr+t+vgtpywmAPEv++  +k Y  k

Q: 421   HRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVT--RKAYGPK  478

         ***************************************************..9******

S: 181   aDiwslGItaielaegepPfkdleplkallkilkneppklkskkkfskefkefvekclqk  240

         +DiwslGI+aie++egepP+ +++pl+al++i++n +p+l++++k+s  f++f+++cl+

Q: 479   VDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAVFRDFLNRCLEM  538

         ************************************************************

S: 241   npekRpsasellkhkFl  257

         ++ekR sa+ell+h+Fl

Q: 539   DVEKRGSAKELLQHQFL  555

         ****************7

Domain Sequence
(FASTA)

YTRFEKIGQG ASGTVYTAID IATGQEVAIK QMNLQQQPKK ELIINEILVM RENKNPNIVN 60

YLDSYLVGDE LWVVMEYLAG GSLTDVVTET CMDEAQIAAV CRECLQALEF LHCNQVIHRD 120

IKSDNILLGM DGSVKLTDFG FCAQITPEQS KRSTMVGTPY WMAPEVVTRK AYGPKVDIWS 180

LGIMAIEMIE GEPPYLNENP LRALYLIATN GTPELQNPEK LSAVFRDFLN RCLEMDVEKR 240

GSAKELLQHQ FL 252

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000095	; PAK_box_Rho-bd.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00786	; PBD; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00285	; PBD; 1.
SM00220	; S_TKc; 1.

Prosites

PS50108	; CRIB; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013