EKS-DAR-00856

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DAR-00856

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CK1/CK1	503.1	2.8E-151	17	277	261

Status

Unreviewed

Ensembl Protein

ENSDARP00000104911

UniProt Accession

Q8JHE0;

Protein Name

Protein Synonyms/Alias

Casein kinase 1-alphaLS; Csnk1a1 protein;

Gene Name

csnk1a1

Gene Synonyms/Alias

csnk1a1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDARG00000052674	ENSDARP00000107253	ENSDART00000121429
ENSDARG00000052674	ENSDARP00000104911	ENSDART00000130655

Organism

Danio rerio

Functional Description

Protein Length

337

Protein Sequence
(FASTA)

MASSSGSKAE FIVGGKYKLV RKIGSGSFGD IYLAINITNG EEVAVKLESQ KARHPQLLYE 60

SKLYKILQGG VGIPHIRWYG QEKDYNVLVM DLLGPSLEDL FNFCSRRFTM KTVLMLADQM 120

ISRIEYVHTK NFIHRDIKPD NFLMGIGRHC NKLFLIDFGL AKKYRDNRTR QHIPYREDKN 180

LTGTARYASI NAHLGIEQSR RDDMESLGYV LMYFNRTSLP WQGLKAATKK QKYEKISEKK 240

MSTPVEVLCK GFPAEFAMYL NYCRGLRFEE APDYMYLRQL FRILFRTLNH QYDYTFDWTM 300

LKQKAAQQAA SSGGQGQQAQ TPTGKQTDKP KSNMKGF 337

Nucleotide Sequence
(FASTA)

ATGGCCAGCA GCAGTGGCTC TAAAGCCGAG TTTATAGTCG GTGGGAAATA CAAGCTCGTT 60

CGTAAAATCG GATCTGGATC CTTCGGTGAC ATTTATTTGG CAATCAACAT CACAAATGGA 120

GAGGAGGTAG CTGTGAAATT GGAATCACAG AAAGCCAGAC ATCCTCAACT CCTATATGAA 180

AGCAAATTGT ACAAAATTCT CCAGGGAGGA GTCGGGATCC CACACATCAG GTGGTATGGC 240

CAAGAAAAGG ACTATAATGT CCTAGTCATG GACCTGCTCG GCCCAAGTCT GGAAGATCTC 300

TTTAACTTCT GTTCGCGCAG ATTCACAATG AAAACTGTCC TAATGCTTGC AGATCAGATG 360

ATCAGCAGAA TCGAGTATGT GCACACAAAA AACTTCATCC ACAGAGATAT CAAGCCAGAC 420

AACTTTTTAA TGGGTATTGG CCGTCACTGT AATAAGTTGT TCCTCATCGA TTTTGGTCTG 480

GCCAAGAAAT ACAGAGACAA CAGGACACGA CAGCACATAC CCTACAGAGA AGACAAAAAC 540

CTCACAGGCA CAGCTCGCTA TGCCAGCATC AACGCACACT TGGGCATCGA GCAGAGTCGT 600

CGAGATGACA TGGAGTCGCT AGGATATGTC CTGATGTACT TCAACAGAAC CAGCCTGCCT 660

TGGCAGGGAC TGAAGGCTGC CACAAAGAAA CAGAAATATG AGAAGATTAG TGAGAAAAAG 720

ATGTCGACCC CTGTTGAGGT GTTGTGTAAG GGTTTCCCAG CAGAGTTTGC CATGTACCTG 780

AACTACTGTC GTGGGTTGCG GTTTGAAGAG GCGCCTGACT ACATGTACCT GCGTCAGCTT 840

TTCCGCATTC TTTTCAGGAC TCTGAACCAC CAGTATGACT ACACATTTGA CTGGACCATG 900

CTGAAGCAGA AAGCAGCACA GCAAGCGGCC TCCTCAGGGG GACAGGGGCA ACAGGCACAA 960

ACCCCCACAG GCAAGCAAAC TGACAAACCC AAGAGTAACA TGAAAGGTTT CTAA 1014

Domain Profile

S: 1     yrvvkkiGsGsfGdiylgknlasgeevaikleskkskapqlklesrvykilqggvgiPev  60

         y++v+kiGsGsfGdiyl++n+++geeva+kles+k+++pql +es++ykilqggvgiP++

Q: 17    YKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHI  76

         89**********************************************************

S: 61    ryfgkekkynvlvldllGpsledlfdlcerkfslktvllladqlisrieyvhskeliyrd  120

         r++g+ek+ynvlv+dllGpsledlf++c+r+f++ktvl+ladq+isrieyvh+k++i+rd

Q: 77    RWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRD  136

         ************************************************************

S: 121   ikPdnfllgigrkgkkvylidfGlakkyrdaktkkhipyreeksltGtaryasinthlgk  180

         ikPdnfl+gigr+++k++lidfGlakkyrd++t++hipyre+k+ltGtaryasin+hlg+

Q: 137   IKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGI  196

         ************************************************************

S: 181   eqsrrddleslgyvllyflrgslPWqglkaatkkqkyekisekklstsievlcegfPeef  240

         eqsrrdd+eslgyvl+yf+r+slPWqglkaatkkqkyekisekk+st++evlc+gfP+ef

Q: 197   EQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEF  256

         ************************************************************

S: 241   atylkyvrklkfeekPdyeyl  261

         a+yl+y+r l+fee+Pdy+yl

Q: 257   AMYLNYCRGLRFEEAPDYMYL  277

         *******************97

Domain Sequence
(FASTA)

YKLVRKIGSG SFGDIYLAIN ITNGEEVAVK LESQKARHPQ LLYESKLYKI LQGGVGIPHI 60

RWYGQEKDYN VLVMDLLGPS LEDLFNFCSR RFTMKTVLML ADQMISRIEY VHTKNFIHRD 120

IKPDNFLMGI GRHCNKLFLI DFGLAKKYRD NRTRQHIPYR EDKNLTGTAR YASINAHLGI 180

EQSRRDDMES LGYVLMYFNR TSLPWQGLKA ATKKQKYEKI SEKKMSTPVE VLCKGFPAEF 240

AMYLNYCRGL RFEEAPDYMY L 261

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tupaia belangeri"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007507	; P:heart development
GO:0018105	; P:peptidyl-serine phosphorylation

KEGG

dre:100334765

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013