| Tag | Content |
|---|
| EKPD ID | EPS-DAR-00021 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| DSP/aDSP | 135.4 | 2.6E-39 | 5 | 141 | 137 |
|
| Status | Reviewed |
| Ensembl Protein | ENSDARP00000073347 |
| UniProt Accession | Q1LWL2; Q6DGQ6; |
| Protein Name | Dual specificity protein phosphatase 22-A |
| Protein Synonyms/Alias | |
| Gene Name | dusp22a |
| Gene Synonyms/Alias | dusp22a; dusp22; si:dkey-190g1.1, zgc:92816; |
| Ensembl Information | |
| Organism | Danio rerio |
| Functional Description | Activates the Jnk signaling pathway. Dephosphorylatesand deactivates p38 and stress-activated protein kinase/c-Jun N- terminal kinase (SAPK/JNK) (By similarity). |
| Protein Length | 208 |
Protein Sequence
(FASTA) | | MGNGMNKVID GLYLGNIRDS ENRDSLSRNG ITHILSVCNN AKPVLEDMTY LCINAADASS 60 | | QNLSQHFKES IRFIHECRLN GGACLVHCLA GVSRSTTVVV AYLMTVTSYG WQECLTAVKA 120 | | VRSFVGPNYG FQQQLQEFQM KQVSEYQAWL RASYRSSPFK DQEQVEALLS LFAEQQQQGQ 180 | | QNDPEWMSQG SRIYPLSYNQ YSASGSNR 208 |
|
Nucleotide Sequence
(FASTA) | | ATGGGGAATG GAATGAATAA GGTCATTGAT GGTCTCTATC TAGGAAATAT AAGAGATTCA 60 | | GAGAACAGAG ACAGTCTGTC CCGCAATGGC ATCACCCATA TCCTCTCCGT CTGCAACAAT 120 | | GCAAAGCCTG TGTTAGAGGA TATGACCTAT CTGTGCATTA ATGCAGCTGA TGCCTCCAGT 180 | | CAAAACTTAT CTCAACACTT CAAAGAATCC ATACGCTTTA TCCATGAGTG TCGACTTAAT 240 | | GGAGGGGCAT GTCTAGTTCA TTGTCTTGCT GGAGTGTCTC GGAGTACCAC TGTGGTGGTG 300 | | GCTTACCTCA TGACAGTCAC CAGCTATGGC TGGCAAGAGT GTCTTACTGC GGTGAAGGCT 360 | | GTGCGCTCTT TTGTGGGCCC AAACTATGGC TTCCAGCAGC AGCTGCAGGA GTTTCAGATG 420 | | AAACAGGTGT CAGAGTATCA GGCATGGTTG CGGGCCAGCT ATAGATCCAG CCCATTTAAA 480 | | GACCAGGAAC AGGTTGAAGC TTTACTGAGT CTGTTTGCAG AACAGCAGCA ACAAGGACAA 540 | | CAAAATGATC CGGAGTGGAT GAGCCAGGGC TCTCGCATCT ATCCTCTGTC CTACAACCAA 600 | | TACAGTGCCT CGGGCAGCAA CAGGTGA 627 |
|
| Domain Profile | S: 2 vteilpglylgdqataldrreLsklgitvvinaslsvikvqviPeylikkgityknipvd 61 | +++++ glylg+++++ +r +Ls++git+++ + + + +++ty+ i++ | Q: 5 MNKVIDGLYLGNIRDSENRDSLSRNGITHILSVCNNAKP--------VLEDMTYLCINAA 56 | 5899**********************9998877655444........4589********* |
| S: 62 DsdvtdllqyfdeaaefideakekggkvlvHCaaGvsRSatlvlaYLmkveglslsdAie 121 | D+ +++l+q+f+e ++fi+e++ +gg++lvHC aGvsRS+t+v+aYLm+v+ +++ ++ | Q: 57 DASSQNLSQHFKESIRFIHECRLNGGACLVHCLAGVSRSTTVVVAYLMTVTSYGWQECLT 116 | ************************************************************ |
| S: 122 avkrkrpsiepnegfleQLlelekk 146 | avk+ r+ + pn gf +QL e++ k | Q: 117 AVKAVRSFVGPNYGFQQQLQEFQMK 141 | *********************9865 |
|
Domain Sequence
(FASTA) | | MNKVIDGLYL GNIRDSENRD SLSRNGITHI LSVCNNAKPV LEDMTYLCIN AADASSQNLS 60 | | QHFKESIRFI HECRLNGGAC LVHCLAGVSR STTVVVAYLM TVTSYGWQEC LTAVKAVRSF 120 | | VGPNYGFQQQ LQEFQMK 137 |
|
| Keyword | Complete proteome; Cytoplasm; Hydrolase; Nucleus; Protein phosphatase; Reference proteome. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | |
| KEGG | |
| InterPros | |
| Pfam | |
| SMARTs | |
| Prosites | |
| Prints | |
| Created Date | 20-Feb-2013 |