EKS-DAR-00381

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DAR-00381

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/PSK	505.8	4.4E-152	96	353	258

Status

Reviewed

Ensembl Protein

ENSDARP00000073709

UniProt Accession

Q501V0; Q1LWH5;

Protein Name

Serine/threonine-protein kinase H1 homolog

Protein Synonyms/Alias

Gene Name

pskh1

Gene Synonyms/Alias

pskh1; si:ch211-201b11.4, zgc:113034;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDARG00000056713	ENSDARP00000073709	ENSDART00000079253

Organism

Danio rerio

Functional Description

Protein Length

422

Protein Sequence
(FASTA)

MGCRTSKVLP EPPGDVQLDL VKKVEPHQTD VYKNFIKYDG GGEKTGSPSP QGQSQAVAKV 60

SQSPPPANDQ PEPADSHRKK VAKYRAKFDP RVTAKYDIKA LIGRGSFSRV VRVEHRSTRQ 120

PYAIKMIETR YREGREVCES ELCVLRRVRH TNIIQLMEVF ETAERVYMVM ELATGGELFD 180

RIITRGSFTE RDATRVLQMV LDGVKYLHTL GITHRDLKPE NLLYYHPGAD SKIMITDFGL 240

ASTRKKGDEC LMKTTCGTPE YIAPEILVRK PYTNAVDMWA LGVISYILLS GTMPFEDDNR 300

MRLYRQILKG KYSFSGEPWP SVSNLAKDFI DRVLTVDPNE RLSAGQALKH PWIVSMAASS 360

SMKNLHRSIS QNLLKRASSR CHSTKSSQST RSSRSTKSSK ARRLREKELR ELNRRYQQQC 420

NG 422

Nucleotide Sequence
(FASTA)

ATGGGGTGCA GGACAAGCAA AGTCCTCCCA GAACCACCCG GTGACGTCCA ACTTGACCTG 60

GTCAAAAAGG TAGAGCCGCA TCAGACGGAT GTCTACAAAA ACTTCATCAA ATACGATGGT 120

GGTGGGGAGA AAACAGGCTC GCCGTCCCCT CAGGGTCAAA GCCAGGCTGT TGCAAAGGTG 180

AGCCAATCCC CTCCACCGGC TAATGACCAG CCAGAACCTG CTGACTCACA CCGGAAGAAA 240

GTAGCCAAAT ACAGAGCCAA ATTTGACCCT CGAGTGACTG CCAAGTATGA CATTAAAGCT 300

TTGATAGGTC GGGGCAGTTT CAGTCGGGTA GTACGAGTGG AACACAGGAG CACACGGCAG 360

CCATATGCCA TTAAGATGAT CGAGACGCGC TACCGTGAAG GCAGAGAAGT ATGTGAATCT 420

GAACTTTGCG TCCTACGACG TGTGCGCCAC ACTAATATTA TCCAGCTAAT GGAGGTGTTT 480

GAGACGGCTG AGCGGGTCTA CATGGTGATG GAGTTGGCCA CTGGTGGAGA GCTGTTCGAC 540

CGCATCATCA CCCGTGGGTC TTTCACAGAA AGGGACGCCA CACGGGTGCT TCAGATGGTT 600

CTTGATGGGG TGAAGTACCT CCATACATTG GGCATCACGC ACAGGGACTT AAAGCCGGAA 660

AACTTGCTTT ACTACCATCC TGGTGCTGAT TCCAAGATTA TGATCACAGA CTTTGGCTTG 720

GCCAGCACAC GAAAGAAAGG GGACGAATGT TTGATGAAGA CTACCTGTGG AACACCTGAG 780

TACATCGCTC CCGAGATACT CGTTCGCAAA CCATACACTA ATGCAGTAGA TATGTGGGCA 840

CTGGGTGTCA TTTCCTACAT CCTGCTCAGT GGAACCATGC CTTTTGAGGA TGACAATCGA 900

ATGCGTCTGT ATCGACAGAT CCTCAAAGGA AAATACAGCT TCTCTGGGGA GCCATGGCCA 960

AGTGTTTCCA ATCTGGCAAA GGACTTCATC GATCGCGTCC TCACGGTGGA TCCTAATGAG 1020

CGGCTCTCTG CGGGCCAGGC ACTCAAACAC CCCTGGATTG TAAGTATGGC AGCTTCCTCC 1080

TCCATGAAGA ATCTGCACCG GTCCATTTCC CAGAATCTCC TGAAGAGAGC TTCGTCACGC 1140

TGCCACAGCA CAAAATCATC CCAGTCCACT CGCTCCAGCC GCTCCACCAA GTCCAGCAAG 1200

GCACGACGCC TTCGTGAAAA AGAGCTGCGA GAGCTGAACC GCCGGTACCA GCAGCAGTGC 1260

AATGGTTAA 1269

Domain Profile

S: 1     ydikaligkgsfsrvvrvehratrkpfaikvvetkeregreaveselrvlrrvshafiiq  60

         ydikalig+gsfsrvvrvehr+tr+p+aik++et++regre++esel vlrrv+h++iiq

Q: 96    YDIKALIGRGSFSRVVRVEHRSTRQPYAIKMIETRYREGREVCESELCVLRRVRHTNIIQ  155

         9***********************************************************

S: 61    lvevfeteekvylvmelatggelfdrviakgsfterdatrvlkmvldgvrylhalrithr  120

         l+evfet e+vy+vmelatggelfdr+i++gsfterdatrvl+mvldgv+ylh+l+ithr

Q: 156   LMEVFETAERVYMVMELATGGELFDRIITRGSFTERDATRVLQMVLDGVKYLHTLGITHR  215

         ************************************************************

S: 121   dlkpenllyydpgeeskilitdfglayaakksddllmkttcgtpeyiapevllrkpytns  180

         dlkpenllyy+pg +ski+itdfgla+++kk+d++lmkttcgtpeyiape+l+rkpytn+

Q: 216   DLKPENLLYYHPGADSKIMITDFGLASTRKKGDECLMKTTCGTPEYIAPEILVRKPYTNA  275

         ************************************************************

S: 181   vdmwalgviayillsgilpfdddsrtrlyrkilkgkysylgepwpsvselakdfidklle  240

         vdmwalgvi+yillsg++pf+dd+r rlyr+ilkgkys++gepwpsvs+lakdfid++l+

Q: 276   VDMWALGVISYILLSGTMPFEDDNRMRLYRQILKGKYSFSGEPWPSVSNLAKDFIDRVLT  335

         ************************************************************

S: 241   vdagerlsasqalkhewv  258

         vd+ erlsa+qalkh+w+

Q: 336   VDPNERLSAGQALKHPWI  353

         *****************7

Domain Sequence
(FASTA)

YDIKALIGRG SFSRVVRVEH RSTRQPYAIK MIETRYREGR EVCESELCVL RRVRHTNIIQ 60

LMEVFETAER VYMVMELATG GELFDRIITR GSFTERDATR VLQMVLDGVK YLHTLGITHR 120

DLKPENLLYY HPGADSKIMI TDFGLASTRK KGDECLMKTT CGTPEYIAPE ILVRKPYTNA 180

VDMWALGVIS YILLSGTMPF EDDNRMRLYR QILKGKYSFS GEPWPSVSNL AKDFIDRVLT 240

VDPNERLSAG QALKHPWI 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Dasypus novemcinctus"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

dre:554840

;

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013