EKS-DAR-00441

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DAR-00441

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/RSK	365.4	4.0E-109	65	326	262

Status

Unreviewed

Ensembl Protein

ENSDARP00000075502

UniProt Accession

F1R3V1;

Protein Name

Protein Synonyms/Alias

Gene Name

rps6kb1b

Gene Synonyms/Alias

rps6kb1b;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDARG00000058230	ENSDARP00000075502	ENSDART00000081059

Organism

Danio rerio

Functional Description

Protein Length

502

Protein Sequence
(FASTA)

MAGVFDIDLD QPEENVSDDE LEEAQINELM DQCSGFEFNM DDCEKIEISE DNVNQGTENI 60

RPECFELLRV LGKGGYGKVF QVRKVSGAAT GKIFAMKVLK KAMIVRNAKD TAHTKAERNI 120

LEEVKHPFIV DLIYAFQTGG KLYLILEYLS GGELFMQLER EGIFMEDTAC FYLAEISMAL 180

GHLHQKGIIY RDLKPENIML NNQGHVKLTD FGLCKESIHD GTVTHTFCGT IEYMAPEILM 240

RSGHNRAVDW WSLGALMYDM LTGAPPFTGE NRKKTIDKIL KCKLNLPPYL TQEARDLLKR 300

LLKRSASSRL GAGPGDATEV QTHPFFRHVN WDDLLARKVE PPFKPFLQSA EDVSQFDSKF 360

TSQTPVDSPD DSTLSESANQ VFLGFTYVAP SVLENIKEKF SFEPKIRSPR RFLGSPRTPL 420

SPIKFSGDCW PRGPTLPGSS TLQSPTELAM EVSSVDHMDV QASAEATAPL PIRQPAGSNM 480

GQFKQQAYPV ISKRPEHLRM NL 502

Nucleotide Sequence
(FASTA)

ATGGCTGGCG TTTTCGACAT CGATCTGGAC CAGCCAGAGG AGAATGTGTC CGATGACGAG 60

CTGGAGGAGG CTCAGATCAA TGAGCTCATG GACCAGTGCA GTGGCTTTGA GTTTAACATG 120

GATGACTGTG AGAAGATTGA GATATCAGAG GACAATGTGA ACCAAGGCAC AGAGAACATC 180

CGTCCGGAGT GCTTTGAGCT TCTCCGTGTT TTAGGGAAAG GAGGTTATGG AAAGGTTTTC 240

CAAGTTCGGA AAGTATCTGG TGCTGCAACA GGAAAAATAT TTGCAATGAA AGTCTTGAAG 300

AAGGCTATGA TTGTACGCAA CGCCAAGGAC ACAGCGCATA CTAAAGCAGA ACGGAACATC 360

TTAGAGGAAG TCAAGCATCC TTTCATCGTT GATCTAATCT ATGCCTTTCA GACGGGCGGC 420

AAGCTTTACC TCATCCTTGA ATACCTAAGT GGTGGGGAGC TTTTCATGCA GCTGGAGCGA 480

GAGGGAATTT TCATGGAAGA CACGGCCTGC TTTTACCTGG CTGAAATCTC TATGGCGCTC 540

GGACACCTGC ATCAGAAAGG CATCATCTAC AGAGATCTCA AACCTGAGAA CATCATGCTG 600

AACAACCAAG GACATGTAAA ACTGACTGAT TTCGGGCTGT GTAAGGAGTC CATTCATGAC 660

GGCACAGTGA CCCACACTTT CTGCGGCACC ATTGAGTACA TGGCTCCAGA GATCCTCATG 720

AGGAGCGGAC ACAATCGCGC TGTCGACTGG TGGAGTCTGG GGGCTTTAAT GTATGACATG 780

TTAACCGGAG CACCTCCTTT TACAGGAGAG AACCGGAAAA AAACCATTGA CAAAATTCTT 840

AAATGCAAAC TGAACCTCCC ACCCTACCTC ACACAAGAAG CCAGGGACCT TCTCAAAAGG 900

CTACTGAAAA GAAGTGCCTC ATCTCGGCTT GGGGCTGGAC CTGGAGATGC AACAGAAGTA 960

CAGACTCATC CCTTTTTCCG ACATGTTAAT TGGGATGATC TTCTTGCACG CAAAGTAGAA 1020

CCACCATTCA AGCCTTTCTT GCAATCTGCT GAGGATGTGA GCCAGTTTGA TTCAAAGTTC 1080

ACCAGCCAGA CTCCCGTTGA CAGTCCTGAT GACTCCACAC TGAGCGAAAG TGCAAATCAG 1140

GTCTTTTTGG GTTTTACTTA TGTAGCTCCA TCCGTATTGG AAAATATAAA GGAGAAGTTC 1200

TCATTTGAGC CAAAAATCCG TTCACCTCGC CGGTTCTTGG GAAGCCCCCG AACGCCTCTC 1260

AGTCCAATTA AGTTCTCAGG AGATTGTTGG CCACGAGGTC CCACCTTACC CGGATCCTCC 1320

ACCCTCCAGT CCCCCACAGA GCTGGCCATG GAAGTGTCCA GCGTGGATCA CATGGATGTC 1380

CAGGCCAGTG CCGAAGCCAC CGCTCCTCTT CCCATCAGGC AACCCGCTGG CTCCAACATG 1440

GGCCAGTTCA AGCAGCAGGC CTACCCAGTC ATCTCCAAAA GGCCAGAGCA TCTACGTATG 1500

AACCTATGA 1509

Domain Profile

S: 1     fellkvlgkGaygkvflvrkvekkdtgklyavKvlkkaelvk..kkkertkeereiLeev  58

         fell+vlgkG+ygkvf+vrkv++ +tgk++a+Kvlkka +v+  k++++tk+er+iLeev

Q: 65    FELLRVLGKGGYGKVFQVRKVSGAATGKIFAMKVLKKAMIVRnaKDTAHTKAERNILEEV  124

         89***********************************9999999****************

S: 59    ehpfivklheafqdekklylvlellkGgeLlerlkkkklfseeeasfilaelvlaleylH  118

         +hpfiv+l +afq+  klyl+le+l+GgeL+++l+++++f+e++a+f+lae+++al +lH

Q: 125   KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLH  184

         ************************************************************

S: 119   skgvvyrDLkpeNilldeeghvkltDfglakekiaeneekaysfcgTleyvaPevlkrkg  178

         +kg++yrDLkpeNi+l+++ghvkltDfgl+ke+i ++++ +++fcgT+ey+aPe+l+r+g

Q: 185   QKGIIYRDLKPENIMLNNQGHVKLTDFGLCKESI-HDGTVTHTFCGTIEYMAPEILMRSG  243

         *********************************9.9999999******************

S: 179   ydeavDlwslGvllyemLtGktPftgeerketlarilkgkfslklpaweelseeakdlvk  238

         +++avD+wslG+l+y+mLtG++Pftge+rk+t+++ilk+k  l+lp +  l++ea+dl+k

Q: 244   HNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCK--LNLPPY--LTQEARDLLK  299

         ****************************************..9*****..**********

S: 239   klLkkdpakRlga...taeeikehkfl  262

         +lLk+  ++Rlga   +a+e+++h+f+

Q: 300   RLLKRSASSRLGAgpgDATEVQTHPFF  326

         *************9*9*********97

Domain Sequence
(FASTA)

FELLRVLGKG GYGKVFQVRK VSGAATGKIF AMKVLKKAMI VRNAKDTAHT KAERNILEEV 60

KHPFIVDLIY AFQTGGKLYL ILEYLSGGEL FMQLEREGIF MEDTACFYLA EISMALGHLH 120

QKGIIYRDLK PENIMLNNQG HVKLTDFGLC KESIHDGTVT HTFCGTIEYM APEILMRSGH 180

NRAVDWWSLG ALMYDMLTGA PPFTGENRKK TIDKILKCKL NLPPYLTQEA RDLLKRLLKR 240

SASSRLGAGP GDATEVQTHP FF 262

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007165	; P:signal transduction

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR016238	; Ribosomal_S6_kinase.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013