EKS-DAR-00633

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DAR-00633

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/IRE	408.4	2.6E-122	553	816	264

Status

Unreviewed

Ensembl Protein

ENSDARP00000075798

UniProt Accession

F1R365;

Protein Name

Protein Synonyms/Alias

Gene Name

ern2

Gene Synonyms/Alias

ern2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDARG00000058475	ENSDARP00000075798	ENSDART00000081355
ENSDARG00000058475	ENSDARP00000115811	ENSDART00000143587

Organism

Danio rerio

Functional Description

Protein Length

950

Protein Sequence
(FASTA)

VISAVCEKVF SWFSLQCEGG SSVSLPESLL FVSTLDGSLH AVSKQTGDIK WTLKEDPIIQ 60

VPEYFQEPGF LPDPNDGSLY VLGGKRKEGL MKLPFTIQEL VQSSPCRSSD GVLYTGKKQD 120

TWFVVDPQTG EKQTSLSTSS SDSICPSAPL LYIGRTEYMI TMYDTKTQEL RWNATYNDYS 180

APLYDDKKYE YKMSHFASSG DGLVVTVDRD SGEVLWMQKF DSPVAGFYLW SQDSLRRAPH 240

LTVATETLRY LTFTAENTQS HTMKWTYQFT KESHSTKTQL VPTLYVGKTE SHLYASASLV 300

HQGVAIVPKG LTLARIEGPM TAGVTMGNGR PECEITPSTD VKYPPGSSSS LQNQWLLIAG 360

HHEIPPLAHT TMLRDFPENL QRSGDVIPPR GSGSSYRSPS HPRSTNLFCV FQLPPVRKQS 420

SSPVLPDSLS SEPMTVLVVT LLLGAWITFL LTHKWVRNTF TEHTYFNQVV KSNPVKKSQR 480

SEEPVDSTPL SGLTNYSAST ELNTPPSTSS YSNSSRSEKT SSVASNQTQP FSNCDVYSSD 540

EQADVVEVGK ISFSPTEVLG HGTEGTFVFR GHFDGRRVAV KRILPECVEF AEREVQLLRE 600

SDEHPNVIRY FCTERDRQFT YIAIELCAAT LQHCCWMQYV EDPSCPHSEL NPVSLLEQTM 660

CGLSHLHSLN IVHRDLKPRN ILLSLPGALG RVRALISDFG LCKKLPDGRH SFSLRSGIPG 720

TEGWIAPELL INAPKGNPTS AVDIFSAGCV FYYVTSKGQH PFGDTLRRQA NILSGVYNLD 780

HFMEDIHEDV IGRDLIERMI SAEPESRPSA ASILLHEQNC LSCVQMSLLF EDVSDRIEKE 840

PTESPIVARL ENSGRSVVRT NWRMHISAPL QADLRKFRTY KGNSVRDLLR AMRNKKHHYH 900

ELPPEVQSTL GEVPDGFVAY FTSRFPRLLL HTHTALSICA PERPFHPYYH 950

Nucleotide Sequence
(FASTA)

GTGATATCTG CAGTGTGTGA AAAGGTGTTT TCCTGGTTTT CTCTTCAGTG TGAGGGAGGA 60

AGCTCCGTCT CTCTGCCCGA GTCTCTGCTC TTTGTTTCTA CACTGGATGG AAGTCTGCAT 120

GCCGTCAGCA AACAGACCGG AGACATCAAA TGGACACTGA AGGAAGATCC CATTATACAG 180

GTTCCCGAGT ATTTCCAAGA GCCAGGCTTT TTACCAGACC CCAATGACGG AAGTCTGTAT 240

GTTCTCGGAG GAAAGAGGAA AGAAGGTCTG ATGAAACTGC CATTCACTAT TCAAGAGCTG 300

GTGCAGTCGT CTCCCTGCAG GAGCTCAGAT GGAGTACTCT ACACCGGTAA AAAACAGGAC 360

ACCTGGTTTG TGGTCGATCC TCAGACAGGT GAAAAACAGA CAAGTTTGAG CACCTCGTCT 420

TCAGACTCCA TCTGTCCCTC TGCACCTCTG TTGTACATCG GTCGCACAGA ATATATGATC 480

ACCATGTATG ACACGAAGAC TCAGGAGCTC CGCTGGAATG CCACATACAA CGATTACTCA 540

GCTCCTCTAT ATGACGACAA AAAATATGAA TATAAGATGT CGCACTTTGC ATCGAGTGGC 600

GATGGTCTGG TGGTTACGGT GGATCGAGAC TCTGGCGAGG TTTTGTGGAT GCAGAAATTT 660

GATTCTCCGG TGGCTGGATT TTACTTGTGG AGTCAGGACA GTCTCCGTCG AGCCCCTCAT 720

CTGACCGTCG CAACAGAAAC CCTGCGCTAT CTGACCTTCA CCGCAGAAAA CACACAGTCC 780

CACACCATGA AGTGGACCTA CCAGTTCACA AAGGAGAGCC ACAGCACGAA GACTCAGCTA 840

GTTCCCACTC TGTATGTTGG GAAGACGGAG TCTCATCTGT ATGCTTCTGC CTCCCTTGTC 900

CATCAAGGTG TCGCAATAGT GCCTAAGGGT CTCACTCTTG CACGCATTGA GGGGCCGATG 960

ACAGCAGGCG TCACAATGGG TAATGGACGG CCTGAGTGCG AGATCACACC CAGCACTGAC 1020

GTCAAATATC CACCAGGAAG CAGCAGCTCT CTGCAGAATC AGTGGCTGCT CATTGCAGGT 1080

CACCATGAAA TCCCTCCTCT GGCTCACACC ACCATGTTGA GAGATTTCCC AGAGAACCTG 1140

CAGCGCTCTG GTGATGTCAT CCCACCTCGA GGATCCGGCT CTTCTTACCG CTCTCCCTCT 1200

CACCCAAGAA GCACAAATCT GTTCTGTGTT TTCCAGTTGC CACCAGTTAG GAAGCAGAGC 1260

TCTTCTCCAG TGCTGCCAGA CTCGCTGAGC TCTGAGCCCA TGACAGTGCT GGTGGTGACG 1320

CTGCTGCTAG GAGCCTGGAT CACCTTCCTG CTCACACACA AATGGGTCAG AAATACATTT 1380

ACTGAGCATA CCTACTTTAA TCAAGTAGTC AAATCTAATC CTGTAAAAAA ATCCCAAAGA 1440

TCTGAAGAGC CAGTGGACTC CACCCCACTT TCTGGTCTGA CCAATTACAG CGCTTCTACA 1500

GAACTGAACA CTCCGCCCTC AACATCATCT TACAGCAACA GCAGTCGCTC AGAAAAGACC 1560

AGTTCTGTTG CATCCAATCA AACTCAGCCA TTCTCAAATT GTGATGTATA TTCTTCAGAT 1620

GAACAGGCTG ACGTGGTGGA AGTTGGTAAA ATCTCTTTCA GTCCCACTGA GGTGTTGGGT 1680

CATGGGACAG AAGGAACCTT CGTGTTTCGG GGTCATTTTG ACGGTCGGCG TGTGGCGGTG 1740

AAGCGAATCC TGCCGGAGTG TGTGGAGTTT GCAGAGCGAG AGGTTCAACT TCTGCGGGAA 1800

TCAGATGAAC ATCCCAATGT GATCCGTTAC TTCTGCACAG AGCGGGACAG ACAGTTCACT 1860

TACATTGCCA TAGAGCTGTG TGCTGCAACA CTCCAGCATT GTTGCTGGAT GCAGTATGTA 1920

GAAGACCCGA GCTGTCCTCA CTCAGAGCTG AACCCGGTGT CCCTGCTGGA GCAGACCATG 1980

TGTGGCCTCA GTCACCTGCA CTCCCTCAAC ATCGTCCACA GGGATTTAAA GCCCAGGAAT 2040

ATTTTGCTGT CTCTGCCCGG GGCACTGGGT CGAGTGCGGG CGCTCATCTC AGATTTCGGC 2100

TTGTGTAAGA AGCTTCCAGA TGGTCGGCAC AGTTTCAGCC TACGCTCCGG GATACCTGGA 2160

ACCGAAGGCT GGATCGCCCC TGAATTACTC ATAAACGCTC CGAAAGGGAA CCCTACGAGT 2220

GCGGTGGACA TTTTTTCTGC CGGATGTGTG TTTTATTATG TGACGTCTAA AGGACAGCAT 2280

CCGTTCGGTG ACACTCTGCG GCGTCAGGCT AACATCCTCT CTGGAGTCTA TAACCTCGAT 2340

CACTTCATGG AGGATATACA TGAGGACGTG ATTGGCAGAG ATCTGATCGA GCGGATGATC 2400

AGTGCAGAGC CAGAGAGCCG TCCTTCAGCA GCGTCAATTC TTCTGCATGA GCAAAACTGC 2460

TTGTCATGTG TACAAATGTC ATTATTGTTT GAGGACGTCA GTGACAGGAT TGAGAAGGAG 2520

CCTACAGAAA GTCCTATAGT GGCTCGTCTG GAAAATTCTG GCAGATCTGT CGTAAGAACC 2580

AACTGGAGGA TGCACATCTC AGCGCCGCTG CAGGCTGATC TTAGAAAATT TCGTACATAT 2640

AAAGGAAACT CAGTGAGAGA CCTGCTTAGA GCAATGAGGA ATAAAAAACA CCATTATCAC 2700

GAGCTCCCGC CGGAGGTTCA GTCGACTCTC GGTGAAGTCC CCGATGGCTT TGTGGCGTAT 2760

TTCACCTCAC GGTTCCCCCG GTTACTGCTT CACACGCACA CAGCACTCAG CATCTGTGCC 2820

CCCGAGAGAC CCTTTCACCC GTACTATCAT 2850

Domain Profile

S: 1     fspkdvlGkGaeGtvvfrGsfegrevavkrllsefvdlakrevkllresdehpnviryfc  60

         fsp +vlG+G+eGt+vfrG+f+gr vavkr+l+e+v++a+rev+llresdehpnviryfc

Q: 553   FSPTEVLGHGTEGTFVFRGHFDGRRVAVKRILPECVEFAEREVQLLRESDEHPNVIRYFC  612

         7899********************************************************

S: 61    tekdrqfryialelcaaslq.....dyvedkdlelqkelepisllkqiasGlahlhslki  115

         te+drqf yia+elcaa+lq     +yved++   + el+p+sll+q++ Gl+hlhsl+i

Q: 613   TERDRQFTYIAIELCAATLQhccwmQYVEDPSCP-HSELNPVSLLEQTMCGLSHLHSLNI  671

         *******************95555569******9.9************************

S: 116   vhrdlkpqnilislpdakgklrvlisdfGlckkldvGkssfsrrsgvsGteGwiapelle  175

         vhrdlkp+nil+slp a g++r+lisdfGlckkl+ G++sfs rsg++GteGwiapell

Q: 672   VHRDLKPRNILLSLPGALGRVRALISDFGLCKKLPDGRHSFSLRSGIPGTEGWIAPELLI  731

         ************************************************************

S: 176   eltkerltsavdifslGcvfyyvlskGkhpfGdslkrqanilsgelsldklkeekdeevi  235

         + +k ++tsavdifs+Gcvfyyv skG+hpfGd l+rqanilsg ++ld++ e+ +e+vi

Q: 732   NAPKGNPTSAVDIFSAGCVFYYVTSKGQHPFGDTLRRQANILSGVYNLDHFMEDIHEDVI  791

         ************************************************************

S: 236   aedliskmidkdplkrpsakkvlkh  260

          +dli++mi+ +p +rpsa  +l h

Q: 792   GRDLIERMISAEPESRPSAASILLH  816

         **********************998

Domain Sequence
(FASTA)

FSPTEVLGHG TEGTFVFRGH FDGRRVAVKR ILPECVEFAE REVQLLRESD EHPNVIRYFC 60

TERDRQFTYI AIELCAATLQ HCCWMQYVED PSCPHSELNP VSLLEQTMCG LSHLHSLNIV 120

HRDLKPRNIL LSLPGALGRV RALISDFGLC KKLPDGRHSF SLRSGIPGTE GWIAPELLIN 180

APKGNPTSAV DIFSAGCVFY YVTSKGQHPF GDTLRRQANI LSGVYNLDHF MEDIHEDVIG 240

RDLIERMISA EPESRPSAAS ILLH 264

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Ciona savignyi"; ?>Echinops telfairi"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Microcebus murinus"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0016891	; F:endoribonuclease activity, producing 5'-phosphomonoesters
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006397	; P:mRNA processing

KEGG

InterPros

IPR010513	; KEN_RNase_activator.
IPR011009	; Kinase-like_dom.
IPR018391	; PQQ_beta_propeller_repeat.
IPR000719	; Prot_kinase_cat_dom.
IPR006567	; PUG-dom.
IPR011047	; Quinonprotein_ADH-like.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF06479	; Ribonuc_2-5A; 1.

SMARTs

SM00564	; PQQ; 5.
SM00580	; PUG; 1.

Prosites

PS51392	; KEN; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013