EPS-DAR-00043

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-DAR-00043

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	47.6	3.0E-12	121	220	100

Status

Unreviewed

Ensembl Protein

ENSDARP00000076271

UniProt Accession

E7FBM8;

Protein Name

Protein Synonyms/Alias

Gene Name

si:ch73-142c19.2

Gene Synonyms/Alias

si:ch73-142c19.2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDARG00000058873	ENSDARP00000076271	ENSDART00000081832
ENSDARG00000058873	ENSDARP00000122255	ENSDART00000144061

Organism

Danio rerio

Functional Description

Protein Length

658

Protein Sequence
(FASTA)

MDFVRGSSVP RAHYTMVGEA LRYVIPCHMQ CSMGCGGQAC KYEDPSHWSE EQQAIRGIYS 60

SWITDDMLAM ARPSTETIEK FNIIDQFLRC GLKTIINLQC PGEHASCGNP LDPDSGFTYR 120

PETFMEAGIY FYNFRWIDYG VASLTSILDM VKVMSFAIQE GKMAVHCHAG LGRTGVLLAC 180

YLLFTTQMTA DQAILLIRNK RPNSIQTRGQ LQCVRQFAQF LVPLRNLFAN AEPRAPAVTL 240

SQFLIRQKHI LHGLEARQLR YMPKLVPLIS RLLLDIAENR QVIEEDIVEV PDITPVVEKT 300

FNENSIHSFN REMLANGMAM IKPRLPGLPK TNRDNSQPLY YVRKSLSYSD SDLRRLAESL 360

NLPDNPLCVL ASMQLSSMSN QLGAFSCVSQ NSPAPPLGAC KGNPIYSSSS NLWELKTLMD 420

QTEGSPLLKN RRQSFLQRSR SLGVSDEQNT NSIARILSFW KKDRKKSTDQ EETVITEKEH 480

SEVPFITVQS ELSLESRRLL VAQSLAVDLE KDGEKQQTQK VAAWQADLNR QGAWERLCLE 540

KDPFILTGIL WSWLEQLREP IISADDVHTL TESHQDPQTI LSSLDRASRE TVICILDCFA 600

HLFTVPEEIE SAFLERATKA FTKVKNADDG KSVHEVMKKV LKLVLDHLRL IAMNEVEV 658

Nucleotide Sequence
(FASTA)

ATGGATTTTG TGAGGGGTTC CAGTGTTCCC AGAGCGCACT ACACAATGGT TGGAGAGGCG 60

CTGCGTTATG TGATCCCCTG TCATATGCAG TGCTCGATGG GATGTGGAGG ACAAGCCTGC 120

AAATACGAGG ACCCTTCGCA CTGGAGTGAG GAGCAGCAGG CCATCAGAGG AATCTACTCT 180

TCATGGATTA CTGATGACAT GCTTGCAATG GCCCGTCCTT CCACTGAAAC GATTGAAAAA 240

TTCAACATTA TAGACCAGTT TCTGAGATGT GGTTTGAAGA CAATTATTAA CCTCCAGTGC 300

CCTGGTGAAC ATGCTAGCTG TGGAAACCCG CTGGATCCCG ACAGTGGCTT TACTTACCGA 360

CCAGAGACCT TCATGGAGGC TGGCATATAT TTCTACAACT TTAGATGGAT TGACTACGGC 420

GTGGCGTCTC TCACATCTAT CCTGGATATG GTGAAAGTCA TGTCTTTTGC CATCCAAGAA 480

GGCAAAATGG CTGTTCACTG TCATGCAGGG CTGGGCAGAA CAGGTGTGCT TCTGGCCTGT 540

TACTTGCTCT TCACCACACA GATGACAGCA GATCAAGCCA TTCTGTTAAT TCGAAACAAG 600

CGACCAAACT CCATCCAGAC TCGAGGACAG CTCCAGTGCG TCAGACAGTT TGCTCAGTTC 660

CTAGTCCCGC TAAGAAACCT GTTTGCCAAC GCTGAGCCCA GAGCTCCAGC TGTTACTCTT 720

TCCCAGTTCC TGATCCGTCA GAAACACATC CTGCACGGCC TGGAGGCTCG ACAGTTGAGA 780

TACATGCCAA AGCTGGTCCC GCTTATCTCC AGGCTCCTCC TGGACATCGC GGAGAACCGT 840

CAGGTTATTG AGGAGGACAT CGTCGAGGTT CCTGACATCA CGCCGGTGGT GGAGAAAACA 900

TTTAATGAAA ATTCAATACA TAGCTTTAAC AGAGAGATGC TGGCAAACGG GATGGCTATG 960

ATCAAGCCAC GTCTTCCAGG TCTACCCAAA ACCAACAGAG ACAACTCGCA GCCGCTTTAC 1020

TACGTCCGTA AGAGCCTTAG CTACAGCGAT TCCGACCTGC GGAGGTTAGC AGAATCTCTG 1080

AACCTCCCAG ATAACCCTCT GTGTGTGTTG GCCAGCATGC AGTTGTCCTC TATGAGCAAT 1140

CAGCTGGGGG CCTTTAGCTG TGTGTCCCAG AACAGTCCGG CTCCTCCGCT AGGAGCCTGT 1200

AAAGGCAATC CCATCTACAG CTCCAGCAGC AATTTATGGG AGCTGAAGAC TCTGATGGAC 1260

CAGACAGAGG GATCTCCGCT GCTCAAAAAC AGGAGGCAGT CTTTCCTGCA GCGGAGCAGG 1320

TCTTTGGGCG TTTCAGATGA GCAGAACACC AACAGCATTG CCAGAATATT GTCCTTCTGG 1380

AAGAAGGACA GGAAAAAGAG TACCGACCAA GAAGAGACTG TAATTACTGA GAAAGAGCAT 1440

TCAGAGGTGC CCTTCATCAC TGTCCAGTCA GAGCTGTCTC TGGAGTCCCG CCGCCTGCTT 1500

GTGGCTCAGT CTCTTGCAGT GGACCTAGAG AAGGATGGAG AGAAGCAACA AACTCAAAAA 1560

GTGGCTGCTT GGCAGGCGGA TCTTAATCGG CAGGGTGCGT GGGAGCGACT GTGTTTGGAA 1620

AAAGACCCCT TTATTCTGAC TGGAATCCTG TGGTCGTGGC TGGAGCAGCT CAGAGAACCA 1680

ATCATCTCAG CTGATGATGT CCACACGCTT ACAGAGTCCC ATCAGGACCC CCAAACCATC 1740

CTCAGCAGCC TGGACAGGGC TTCGAGGGAA ACGGTGATAT GCATTCTGGA CTGTTTCGCT 1800

CATTTGTTCA CAGTTCCTGA GGAGATTGAG AGCGCATTTC TGGAGCGAGC TACAAAGGCT 1860

TTCACAAAGG TGAAAAACGC AGATGATGGG AAGAGCGTTC ATGAAGTCAT GAAGAAGGTC 1920

TTGAAGCTGG TTCTGGATCA TCTGAGGTTG ATCGCTATGA ATGAGGTTGA GGTGTAG 1977

Domain Profile

S: 45    PeylikkgityknipvdDsdvtdllqyfdeaaefideakekggkvlvHCaaGvsRSatlv  104

         Pe +++ gi + n    D  v  l + +d++   + +   ++gk+ vHC+aG++R+++l+

Q: 121   PETFMEAGIYFYNFRWIDYGVASLTSILDMVK--VMSFAIQEGKMAVHCHAGLGRTGVLL  178

         66666666666666666666666666666553..45668899******************

S: 105   laYLmkveglslsdAieavkrkrpsiepnegfleQLlelekk  146

          +YL+ ++++++++Ai  +++krp+ ++++g+l+  +++ +

Q: 179   ACYLLFTTQMTADQAILLIRNKRPNSIQTRGQLQCVRQFAQF  220

         ********************************9999888765

Domain Sequence
(FASTA)

PETFMEAGIY FYNFRWIDYG VASLTSILDM VKVMSFAIQE GKMAVHCHAG LGRTGVLLAC 60

YLLFTTQMTA DQAILLIRNK RPNSIQTRGQ LQCVRQFAQF 100

Keyword

Complete proteome; Hydrolase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Callithrix jacchus"; ?>Canis familiaris"; ?>Choloepus hoffmanni"; ?>Equus caballus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0004725	; F:protein tyrosine phosphatase activity
GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0035335	; P:peptidyl-tyrosine dephosphorylation

KEGG

dre:570928

;

InterPros

IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR000387	; Tyr/Dual-specificity_Pase.
IPR016130	; Tyr_Pase_AS.

Pfam

PF00782

; DSPc; 1.

SMARTs

Prosites

PS00383	; TYR_PHOSPHATASE_1; 1.
PS50056	; TYR_PHOSPHATASE_2; 1.

Prints

Created Date

20-Feb-2013