EKS-DAR-00504

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DAR-00504

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	487.8	2.0E-146	4	285	282

Status

Unreviewed

Ensembl Protein

ENSDARP00000076797

UniProt Accession

F1QUT2;

Protein Name

Protein Synonyms/Alias

Gene Name

mak

Gene Synonyms/Alias

mak;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDARG00000059287	ENSDARP00000076797	ENSDART00000082362

Organism

Danio rerio

Functional Description

Protein Length

633

Protein Sequence
(FASTA)

MNRYTTLKQL GDGTYGSVLM GKSNESGELV AIKRMKRKFY SWEECMNLRE VKSLKKLNHA 60

NVVKLKEVIR ENDHLYFVFE YMKENLYQLM KDRENKMFTE NEIRNIMFQV LSGLAFVHKH 120

GFFHRDMKPE NLLCMGPELV KIADFGLARE IRSRPPYTDY VSTRWYRAPE VLLRSPVYSS 180

PIDIWAVGCI MAELYTLRPL FPGNSEVDEI FKICQVLGTV KKSDWPEGHQ LASAMNFRFP 240

QCVPTPLKTL IPNATNEALD IMRDLLQWDP KKRPSAVKAL RYPYFQVGQL LGPRPMTPDA 300

RKAPVKAVLP SELRSEMQSV SEPVLPSQTK GQSRNSHQPL QQIPLPQSLT QTDTVALHTQ 360

KVVGGENSLM GLKNGRRRWG QTNMKPSDSW DDSDCSDTAA SLSKKPSKGP EEEKTTPQPK 420

EQKPLYTFST VTKLPNTSRL NQSDSSHQST SSARQHYLRQ SRYMPGLISK NTQSLGSKES 480

QQDFWDTSAL MSKPLAPIGG APMSRISPGN FVTTTYNLSG GYIPSFQKKE VGSVGQRIQL 540

APLGHQHALD LSATADCKTG KAKPSKSKPS STVSVNDNSE DYDGWKRRAE RTQLKGTSYS 600

ALGKNSANLI THAPSVQPVH GRIDWAAKYG SHR 633

Nucleotide Sequence
(FASTA)

ATGAACCGTT ACACTACACT CAAGCAGCTG GGTGATGGAA CCTATGGCAG CGTTCTAATG 60

GGGAAGAGCA ACGAGTCTGG AGAACTAGTG GCCATCAAGA GAATGAAGAG GAAGTTCTAC 120

TCTTGGGAGG AGTGCATGAA TCTGAGAGAA GTCAAGTCGC TGAAGAAACT GAATCATGCT 180

AATGTGGTGA AGCTAAAGGA GGTGATACGA GAGAATGATC ACTTGTACTT TGTCTTTGAA 240

TACATGAAAG AAAACCTCTA CCAGCTCATG AAAGACAGGG AAAATAAGAT GTTTACTGAG 300

AATGAAATAA GGAACATCAT GTTTCAAGTT CTCTCTGGTT TGGCATTTGT GCACAAGCAT 360

GGATTTTTTC ACCGTGATAT GAAACCAGAA AATTTGTTAT GTATGGGTCC TGAGTTGGTG 420

AAAATTGCTG ACTTTGGATT GGCACGTGAG ATCCGCTCTC GGCCACCTTA CACAGACTAC 480

GTCTCAACGC GATGGTATCG AGCTCCAGAG GTGCTGTTGA GGTCACCAGT GTATAGTTCA 540

CCCATAGACA TCTGGGCAGT AGGCTGCATC ATGGCTGAGC TCTACACGCT ACGACCTCTG 600

TTTCCTGGCA ACAGTGAGGT GGATGAGATC TTCAAGATCT GTCAGGTCCT TGGTACAGTA 660

AAGAAGTCAG ACTGGCCGGA GGGTCATCAG CTAGCTTCTG CAATGAATTT CCGCTTCCCA 720

CAGTGTGTTC CTACACCACT AAAAACCCTG ATCCCCAATG CCACCAATGA GGCTTTAGAC 780

ATCATGAGAG ACCTCCTCCA ATGGGACCCA AAGAAAAGAC CTTCTGCTGT AAAGGCACTC 840

AGATACCCAT ATTTCCAAGT GGGACAACTT TTGGGCCCCC GTCCTATGAC CCCTGATGCA 900

CGGAAGGCTC CGGTAAAGGC AGTCCTGCCT AGTGAACTCC GATCAGAGAT GCAATCTGTC 960

TCAGAACCAG TGCTGCCATC ACAGACTAAA GGCCAAAGCA GAAACTCACA TCAGCCACTC 1020

CAGCAGATTC CTCTGCCTCA GTCTCTCACA CAGACGGACA CTGTTGCTCT ACACACACAG 1080

AAGGTGGTCG GAGGAGAGAA CAGTCTGATG GGGCTGAAGA ATGGACGTCG AAGGTGGGGA 1140

CAGACCAACA TGAAACCCTC AGACAGCTGG GATGATTCCG ACTGCTCTGA TACTGCAGCG 1200

TCCCTCTCTA AAAAACCCAG CAAAGGTCCT GAGGAGGAGA AAACTACCCC ACAGCCCAAG 1260

GAACAGAAAC CCCTTTACAC ATTTAGCACT GTGACTAAGT TACCGAACAC CAGCAGGCTG 1320

AACCAGTCAG ATTCCAGTCA TCAGAGCACC TCCTCAGCCA GACAGCATTA CCTACGCCAA 1380

TCCAGATACA TGCCAGGGTT AATAAGCAAA AACACACAAT CTTTGGGTAG CAAGGAGTCG 1440

CAACAAGACT TCTGGGACAC CTCAGCTCTG ATGAGTAAAC CTCTTGCGCC CATTGGAGGA 1500

GCACCAATGT CCAGAATCAG CCCAGGAAAC TTTGTAACTA CAACATACAA TCTCTCTGGA 1560

GGATACATAC CTTCTTTTCA GAAGAAGGAA GTGGGTTCCG TAGGCCAGAG GATTCAGCTC 1620

GCTCCTCTCG GTCACCAACA TGCACTTGAT CTTTCTGCCA CTGCTGACTG TAAAACTGGC 1680

AAAGCTAAAC CTTCAAAGTC CAAACCTTCC TCTACAGTTT CAGTCAATGA TAACTCTGAA 1740

GATTATGATG GATGGAAAAG GAGAGCAGAA CGAACCCAGC TTAAAGGAAC AAGCTACTCA 1800

GCCCTGGGCA AAAATTCAGC CAATCTTATC ACTCATGCGC CATCAGTTCA GCCAGTGCAT 1860

GGGCGAATTG ACTGGGCTGC AAAATATGGA AGCCATCGTT AG 1902

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         y+++k+lGdGt+g+vl++ks+++gelvaik+mkrkf+s+ee++nlrevkslkkln h+n+

Q: 4     YTTLKQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWEECMNLREVKSLKKLN-HANV  62

         99*****************************************************.****

S: 61    iklkeviidrendslylvlelmeenlyqlikdr.rkllsesklksilyqilkglafihkh  119

         +klkevi  rend+ly+v+e+m+enlyql+kdr +k+++e+++++i++q+l+glaf+hkh

Q: 63    VKLKEVI--RENDHLYFVFEYMKENLYQLMKDReNKMFTENEIRNIMFQVLSGLAFVHKH  120

         *******..***********************73689***********************

S: 120   gffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgvyss  179

         gffhrd+kPen+l++g+elvk+adfGlare+rs++PytdyvstrwyraPevllrs vyss

Q: 121   GFFHRDMKPENLLCMGPELVKIADFGLAREIRSRPPYTDYVSTRWYRAPEVLLRSPVYSS  180

         ************************************************************

S: 180   pldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasalnlkfp  239

         p+d+wavGc++ae+++lrplfPG se+d+ifki++vlGt kk++w+e+++lasa+n++fp

Q: 181   PIDIWAVGCIMAELYTLRPLFPGNSEVDEIFKICQVLGTVKKSDWPEGHQLASAMNFRFP  240

         ************************************************************

S: 240   qvegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         q+++++lktl++na +eal++++dll++dP++r++a +al+ypyf

Q: 241   QCVPTPLKTLIPNATNEALDIMRDLLQWDPKKRPSAVKALRYPYF  285

         ********************************************9

Domain Sequence
(FASTA)

YTTLKQLGDG TYGSVLMGKS NESGELVAIK RMKRKFYSWE ECMNLREVKS LKKLNHANVV 60

KLKEVIREND HLYFVFEYMK ENLYQLMKDR ENKMFTENEI RNIMFQVLSG LAFVHKHGFF 120

HRDMKPENLL CMGPELVKIA DFGLAREIRS RPPYTDYVST RWYRAPEVLL RSPVYSSPID 180

IWAVGCIMAE LYTLRPLFPG NSEVDEIFKI CQVLGTVKKS DWPEGHQLAS AMNFRFPQCV 240

PTPLKTLIPN ATNEALDIMR DLLQWDPKKR PSAVKALRYP YF 282

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013