EKS-DAR-00564

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DAR-00564

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	338.4	4.8E-101	17	269	253

Status

Unreviewed

Ensembl Protein

ENSDARP00000079966

UniProt Accession

A5WUM0;

Protein Name

Protein Synonyms/Alias

Novel protein similar to vertebrate protein kinase, AMP-activated, alpha 1 catalytic subunit (PRKAA1);

Gene Name

prkaa1

Gene Synonyms/Alias

prkaa1; DKEY-226M8.8-001;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDARG00000060596	ENSDARP00000079966	ENSDART00000085531

Organism

Danio rerio

Functional Description

Protein Length

573

Protein Sequence
(FASTA)

MATDKQKHEG RVKIGHYILG DTLGVGTFGK VKVGQHELTK HQVAVKILNR QKIRSLDVVG 60

KIRREIQNLK LFRHPHIIKL YQVISTPTDI FMVMEYVSGG ELFDYICKNG KLDEKESRRL 120

FQQIISGVDY CHRHMVVHRD LKPENVLLDA HMNAKIADFG LSNMMSDGEF LRTSCGSPNY 180

AAPEVISGRL YAGPEVDIWS SGVILYALLC GTLPFDDDHV PTLFKKICDG IFFTPQYLNP 240

SVISLLKHML QVDPMKRATI KEIREDEWFK QDLPKYLFPE DAAYSSNMID EEALKEVCEK 300

CECTEEEVLN CLYSRNHQDP LAVAYHLIID NRRIMSEAKD FYLASSPPDS FLDDLPAHHS 360

AKVHPERVPF LVAESQPRPR HTLDELNPQK SKHLGVRRAK WHLGIRSQSR PNDIMSEVCR 420

AMKQLDYEWK VVNPYYLRVR RKNPVTGMHT KMSLQLYQVD SRTYLLDFRS IDDDMMEVKS 480

GTATPHRSGS VGNYRTTLKN DKSEKNECED AAKGEASAPS TPPISASKVA EGSLASSLTS 540

SVDSTGGEIL PRPGSHTIEF FEMCANLIKL LAR 573

Nucleotide Sequence
(FASTA)

ATGGCGACGG ACAAACAGAA ACATGAAGGC AGGGTGAAAA TTGGACATTA TATACTGGGA 60

GACACGCTAG GAGTGGGGAC GTTCGGAAAA GTCAAAGTTG GCCAGCATGA GCTGACGAAG 120

CATCAAGTGG CCGTGAAGAT TCTAAACCGA CAGAAGATCC GCAGTCTGGA TGTGGTGGGG 180

AAAATTCGAC GTGAAATCCA GAATCTCAAA CTTTTTCGTC ACCCACACAT AATCAAACTT 240

TACCAAGTTA TCAGCACACC GACAGACATC TTCATGGTGA TGGAATATGT GTCTGGAGGA 300

GAACTCTTCG ACTACATCTG TAAAAATGGC AAGTTGGATG AGAAGGAGAG CAGGCGTCTG 360

TTCCAGCAGA TCATCTCAGG GGTGGATTAC TGCCACAGAC ATATGGTGGT GCACAGAGAC 420

CTCAAGCCTG AGAACGTCCT GCTGGATGCG CACATGAATG CCAAGATTGC AGATTTTGGC 480

TTATCAAACA TGATGTCAGA TGGAGAGTTT CTAAGGACGA GTTGTGGCTC TCCTAACTAT 540

GCTGCTCCAG AAGTCATCTC TGGAAGGTTA TACGCAGGGC CCGAGGTGGA CATCTGGAGC 600

AGTGGAGTGA TTTTGTACGC TCTACTGTGC GGGACGCTGC CGTTTGATGA CGACCACGTG 660

CCAACACTGT TCAAGAAGAT CTGCGATGGG ATCTTCTTCA CGCCTCAGTA TCTGAACCCC 720

TCCGTTATAA GCCTTCTAAA ACACATGCTC CAAGTGGACC CCATGAAGAG AGCCACCATC 780

AAAGAGATTC GGGAGGACGA GTGGTTTAAG CAGGATCTTC CCAAGTATCT GTTCCCTGAA 840

GACGCTGCAT ATAGCAGTAA TATGATTGAT GAGGAGGCGC TGAAGGAGGT GTGTGAGAAG 900

TGTGAGTGCA CTGAGGAGGA GGTGCTCAAC TGCTTGTACA GTCGCAATCA CCAGGATCCT 960

CTTGCTGTGG CCTATCACTT GATCATAGAC AACCGCCGCA TTATGAGCGA AGCCAAAGAC 1020

TTCTATTTGG CCTCCAGCCC GCCAGACAGC TTCCTAGACG ATCTTCCCGC TCATCACTCA 1080

GCTAAGGTTC ACCCTGAGCG AGTGCCCTTC CTAGTGGCTG AGTCTCAGCC ACGTCCTCGG 1140

CACACACTAG ATGAGCTTAA TCCCCAGAAG TCCAAGCATC TTGGTGTACG GCGAGCCAAG 1200

TGGCACCTGG GAATCCGCAG CCAGAGCAGG CCGAATGACA TCATGAGCGA GGTCTGTCGT 1260

GCCATGAAGC AGCTGGACTA TGAGTGGAAG GTAGTAAATC CTTATTACTT GAGAGTGCGA 1320

AGGAAGAACC CAGTCACTGG CATGCATACA AAGATGAGCC TCCAGCTCTA CCAAGTGGAC 1380

AGCAGGACCT ATTTACTAGA CTTCAGGAGC ATAGACGATG ACATGATGGA GGTAAAATCA 1440

GGAACCGCTA CACCTCACCG CTCGGGCTCA GTCGGGAATT ACCGGACTAC CCTAAAGAAC 1500

GACAAAAGTG AGAAAAACGA ATGTGAGGAC GCTGCAAAAG GCGAAGCGTC TGCACCTTCC 1560

ACGCCTCCGA TTTCCGCAAG TAAAGTGGCG GAAGGCTCTC TGGCCTCTTC TCTTACCTCG 1620

TCTGTGGATT CCACCGGTGG AGAAATCCTC CCCCGTCCTG GAAGCCACAC CATAGAGTTC 1680

TTCGAGATGT GCGCCAACCT CATCAAGCTG CTAGCACGAT AA 1722

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkkl.seeslekikrEieilkklkhpn  59

         y l++tlG g+fgkVk+ +h++tk++vavKi++++k+ s + + ki+rEi+ lk ++hp+

Q: 17    YILGDTLGVGTFGKVKVGQHELTKHQVAVKILNRQKIrSLDVVGKIRREIQNLKLFRHPH  76

         8899********************************96667788****************

S: 60    iikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgi  119

         iikl++vi+t +++++v+ey+sggeLfdyi ++g+l+eke+r+lf+q++s+v+Y+h++ +

Q: 77    IIKLYQVISTPTDIFMVMEYVSGGELFDYICKNGKLDEKESRRLFQQIISGVDYCHRHMV  136

         ************************************************************

S: 120   vHrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkv  179

         vHrDlKpeN+lld+++n kiaDFGl+n++++g+ l+t+cGsp+YaaPe+++g+ Y gp+v

Q: 137   VHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEV  196

         ************************************************************

S: 180   DvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpek  239

         D+Ws Gv+Lyal++g+lPfd++++ +l++ki +g + +p++l+++++sLl+++L+vdp k

Q: 197   DIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFFTPQYLNPSVISLLKHMLQVDPMK  256

         ************************************************************

S: 240   Ratieeilkhewl  252

         Rati+ei+++ew+

Q: 257   RATIKEIREDEWF  269

         ************7

Domain Sequence
(FASTA)

YILGDTLGVG TFGKVKVGQH ELTKHQVAVK ILNRQKIRSL DVVGKIRREI QNLKLFRHPH 60

IIKLYQVIST PTDIFMVMEY VSGGELFDYI CKNGKLDEKE SRRLFQQIIS GVDYCHRHMV 120

VHRDLKPENV LLDAHMNAKI ADFGLSNMMS DGEFLRTSCG SPNYAAPEVI SGRLYAGPEV 180

DIWSSGVILY ALLCGTLPFD DDHVPTLFKK ICDGIFFTPQ YLNPSVISLL KHMLQVDPMK 240

RATIKEIRED EWF 253

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

dre:100001198

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013