EKS-DAR-00692

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DAR-00692

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	309.8	3.0E-92	31	282	252

Status

Unreviewed

Ensembl Protein

ENSDARP00000116532

UniProt Accession

E7F885;

Protein Name

Protein Synonyms/Alias

Gene Name

taok3a

Gene Synonyms/Alias

taok3a;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDARG00000060751	ENSDARP00000116532	ENSDART00000140668
ENSDARG00000060751	ENSDARP00000080378	ENSDART00000085943

Organism

Danio rerio

Functional Description

Protein Length

896

Protein Sequence
(FASTA)

MMPTSTRKGA VKDPEFANLF FKDDPEEVFC DLHEIGHGSF GAVYFARNSY SNEVVAIKKM 60

SYNGKQTTEK WQDIIKEVKF LEQLRHPNTI EYKGCYLKDN TAWLVMEYCL GSASDLLEVH 120

KKPLQEVEIA AITHGALLGL AYLHSHNMIH RDVKAGNILL TEPGQVKLAD FGSASIASPA 180

NSFVGTPYWM APEVILAMDE GQYEGKVDIW SLGITCIELA ERKPPLFNMN AMSALYHIAQ 240

NDSPTLQSNE WSDAFRSFVD YCLLKIPQDR PSSAELLRHE FVRRDRPLRV LIDLIQRTKD 300

AVRELDNLQY RKMKKILYQE KHNGPMGESQ EEEEDGDQAG CKMNSLGSNH SIPSTSVSTG 360

SQSSSVNSLQ EVPDDSCSEL HHDYDSTLES STQHKKDHQY IRDDIPHRDH RSDLRPSSSE 420

RAQAHNYKNR ERFATIKSAS LVTRQIHEHE QENELREQMS GYKRMRRQHQ KQLIALENKL 480

KAEMDEHRLK LQKELETHAN NAFIELEKLA KKHAIQTDKE MKTLSADEKK FQQQIVAQQK 540

KELTTFLDTQ KKQYKLCKEK IKEEMSEDHS TPKKEKQERL SKHKENIQHS QAEEEAQLLG 600

QQRAFYDRNC RAFKRKIMIK RHEFEQEQLR EELNKKKTQK EMEHAMLIRQ DESTQELEHR 660

QLKTLQKLRM DLIRLQHQTE LENQIEYNNR RERELHRKHV LELRQQPKNL KAMELQIKKQ 720

FQDTCKVQTK QYKALRHHQL EVTPKSEHKT VLKALKDEQT RKLAILAEQY EQSINEMMAS 780

QALRLDEAQE AECQALRQQL QQEMELLNAY QSKIKIQTEA QHEREQQKLE QKVSLRRAHL 840

EQKIEEELAS LQKERTDRIK HLLDRQEREI DAFDMESLRM GFNNLGALDY PKDDYR 896

Nucleotide Sequence
(FASTA)

ATGATGCCAA CGTCCACACG GAAGGGGGCG GTGAAAGACC CGGAGTTTGC CAACCTCTTT 60

TTCAAAGATG ACCCAGAAGA AGTCTTCTGC GACCTGCACG AGATTGGCCA TGGGAGTTTC 120

GGAGCAGTTT ATTTTGCCCG AAACTCCTAT TCCAATGAGG TGGTGGCCAT TAAAAAGATG 180

TCCTACAATG GCAAGCAAAC CACTGAGAAG TGGCAGGACA TCATCAAAGA GGTGAAGTTT 240

CTGGAACAGC TGCGTCATCC AAACACCATT GAATACAAAG GCTGCTACTT GAAGGACAAC 300

ACAGCATGGC TTGTGATGGA GTATTGTCTC GGCTCCGCTT CAGACTTGTT AGAGGTTCAC 360

AAGAAACCCC TCCAAGAGGT TGAAATTGCT GCCATTACCC ACGGTGCCTT GCTAGGACTG 420

GCTTACTTAC ATTCCCACAA CATGATCCAC AGAGATGTGA AGGCTGGTAA TATCCTGCTG 480

ACAGAGCCCG GTCAGGTTAA GCTGGCTGAT TTTGGCTCTG CGTCCATTGC CTCTCCTGCT 540

AACTCTTTTG TTGGAACCCC ATACTGGATG GCTCCTGAAG TGATTTTGGC CATGGATGAG 600

GGTCAGTATG AGGGGAAGGT GGACATCTGG TCTCTGGGGA TCACTTGCAT AGAGCTGGCT 660

GAACGCAAGC CTCCTCTCTT CAACATGAAC GCTATGAGTG CCTTATACCA CATCGCCCAA 720

AACGACTCTC CCACCTTACA GTCCAATGAG TGGTCGGATG CATTCCGGAG TTTCGTTGAC 780

TACTGCCTAC TAAAAATTCC TCAGGACAGA CCCTCCTCAG CAGAACTCCT GCGGCATGAG 840

TTTGTTAGGA GAGATCGTCC TCTACGAGTC CTCATCGATC TTATCCAGAG GACGAAGGAT 900

GCAGTCCGAG AACTGGACAA CCTGCAGTAT CGTAAAATGA AAAAAATCCT CTACCAGGAG 960

AAACACAACG GCCCAATGGG GGAGTCTCAG GAAGAGGAGG AGGATGGAGA TCAGGCGGGC 1020

TGTAAGATGA ACAGTTTGGG CAGTAACCAT TCAATTCCCA GCACCTCAGT GAGCACCGGC 1080

AGTCAGAGCA GCAGCGTGAA CAGCCTGCAG GAGGTGCCGG ACGACTCCTG CTCTGAGCTG 1140

CACCACGACT ACGACAGCAC CCTCGAGTCT TCCACACAAC ACAAAAAGGA TCATCAATAC 1200

ATCCGTGACG ACATTCCTCA TCGGGACCAC CGGTCGGACC TTCGACCGTC CTCGTCTGAG 1260

CGAGCTCAAG CTCACAACTA TAAAAACCGT GAGCGCTTCG CCACCATCAA GTCAGCCTCT 1320

CTGGTTACAC GTCAGATCCA TGAACATGAG CAGGAAAATG AGCTCCGAGA GCAGATGTCG 1380

GGCTATAAAC GCATGCGACG GCAACACCAG AAGCAGCTGA TCGCTTTGGA GAACAAGCTG 1440

AAGGCAGAAA TGGACGAACA CAGACTGAAA CTTCAGAAAG AACTGGAAAC CCACGCCAAT 1500

AATGCCTTCA TCGAGCTGGA GAAACTCGCC AAGAAGCATG CCATCCAAAC AGACAAAGAA 1560

ATGAAAACTC TGTCAGCTGA TGAGAAGAAG TTTCAGCAGC AGATCGTGGC CCAACAGAAG 1620

AAAGAGCTCA CCACCTTCCT CGACACCCAG AAGAAGCAGT ACAAGCTGTG CAAGGAGAAA 1680

ATCAAAGAGG AGATGAGTGA AGACCACAGC ACGCCTAAGA AGGAGAAGCA GGAGAGGCTG 1740

TCCAAGCACA AGGAGAACAT CCAGCACTCT CAGGCTGAAG AAGAAGCTCA GCTCCTGGGT 1800

CAGCAGAGGG CTTTCTATGA CAGAAACTGC AGGGCCTTCA AACGCAAGAT CATGATTAAG 1860

AGACACGAGT TTGAGCAGGA GCAGTTACGA GAGGAGCTGA ATAAGAAAAA GACCCAGAAG 1920

GAAATGGAGC ACGCCATGTT GATCAGACAA GATGAGTCGA CCCAAGAACT TGAACACAGA 1980

CAGCTGAAGA CGCTACAAAA ACTGCGCATG GATCTGATCC GACTGCAGCA CCAAACAGAA 2040

CTGGAGAACC AAATCGAATA CAACAACCGA AGAGAACGAG AACTGCACAG GAAACATGTG 2100

CTCGAACTTC GGCAGCAGCC CAAGAACCTC AAGGCTATGG AGCTCCAGAT AAAGAAACAG 2160

TTCCAGGACA CGTGTAAAGT CCAGACGAAA CAGTACAAGG CCCTGCGGCA CCATCAGCTA 2220

GAGGTGACCC CCAAAAGCGA GCACAAGACT GTGTTGAAAG CCCTCAAGGA TGAGCAGACG 2280

CGCAAACTGG CCATTCTGGC TGAGCAGTAC GAGCAGAGCA TCAACGAGAT GATGGCGTCA 2340

CAGGCGCTGC GTCTGGATGA GGCTCAAGAG GCTGAATGCC AGGCACTGAG GCAGCAGCTG 2400

CAGCAGGAGA TGGAGTTACT CAATGCCTAC CAGAGCAAGA TCAAGATCCA AACCGAGGCG 2460

CAGCACGAGC GTGAACAGCA GAAGCTGGAG CAGAAAGTCT CTCTGCGCAG AGCACACCTG 2520

GAACAGAAGA TCGAGGAGGA GCTGGCTTCT CTTCAGAAAG AGCGAACCGA CCGAATCAAA 2580

CATCTGCTGG ACCGTCAGGA GAGAGAAATC GACGCCTTCG ACATGGAGAG TCTCCGCATG 2640

GGTTTCAACA ACTTGGGTGC TTTGGACTAC CCTAAAGATG ACTACAGATG A 2691

Domain Profile

S: 3     lleeigkGalgkvylarekktgelvaikkinlekq...ekleelqkeisvlkklkhpniv  59

          l+eig+G++g+vy ar+  ++e+vaikk++++ +   ek+++++ke+++l++l+hpn +

Q: 31    DLHEIGHGSFGAVYFARNSYSNEVVAIKKMSYNGKqttEKWQDIIKEVKFLEQLRHPNTI  90

         5789****************************988889**********************

S: 60    eylesflkeeelwlvmeylagGslsdlvkeelkselkEeqiayilrevlkaLeylHskkv  119

         ey +++lk+++ wlvmey+  Gs+sdl++ ++k++l+E +ia+i++++l +L+ylHs+++

Q: 91    EYKGCYLKDNTAWLVMEYCL-GSASDLLE-VHKKPLQEVEIAAITHGALLGLAYLHSHNM  148

         *******************7.********.******************************

S: 120   iHrdikakniLlteegeVkLsdfgvaaqlektrkkrktvvgtpywmAPEviaqe.ekgYd  178

         iHrd+ka+niLlte g+VkL+dfg+a+  +      +++vgtpywmAPEvi ++ e +Y+

Q: 149   IHRDVKAGNILLTEPGQVKLADFGSASIASP----ANSFVGTPYWMAPEVILAMdEGQYE  204

         ************************9988887....69**************9887999**

S: 179   ekaDiwslGItaielaegepPfkdleplkallkilkneppklkskkkfskefkefvekcl  238

          k+DiwslGIt+ielae++pP++++++++al++i++n++p+l+s+ ++s++f++fv+ cl

Q: 205   GKVDIWSLGITCIELAERKPPLFNMNAMSALYHIAQNDSPTLQSN-EWSDAFRSFVDYCL  263

         ******************************************888.**************

S: 239   qknpekRpsasellkhkFl  257

          k p++Rps++ell+h+F+

Q: 264   LKIPQDRPSSAELLRHEFV  282

         ******************7

Domain Sequence
(FASTA)

DLHEIGHGSF GAVYFARNSY SNEVVAIKKM SYNGKQTTEK WQDIIKEVKF LEQLRHPNTI 60

EYKGCYLKDN TAWLVMEYCL GSASDLLEVH KKPLQEVEIA AITHGALLGL AYLHSHNMIH 120

RDVKAGNILL TEPGQVKLAD FGSASIASPA NSFVGTPYWM APEVILAMDE GQYEGKVDIW 180

SLGITCIELA ERKPPLFNMN AMSALYHIAQ NDSPTLQSNE WSDAFRSFVD YCLLKIPQDR 240

PSSAELLRHE FV 252

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013