EKS-DAR-00822

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DAR-00822

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/SGK	502.5	6.0E-151	152	409	258

Status

Unreviewed

Ensembl Protein

ENSDARP00000084801

UniProt Accession

F1R730;

Protein Name

Protein Synonyms/Alias

Gene Name

sgk3

Gene Synonyms/Alias

sgk3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDARG00000062460	ENSDARP00000084801	ENSDART00000090368

Organism

Danio rerio

Functional Description

Protein Length

486

Protein Sequence
(FASTA)

MEEQPSCPNV SIPCYNEQRD KKKRYTVYKV MVSVGRHEWF VFRRYAEFDK LYNTLKKQFP 60

ALNLKIPAKR IFGDNFDPEF IKQRRAGLHE FIQRIVSHSQ LCSHPDVKVF LQMDKAKNFS 120

DGSEDEDDKS NSTSRNINLG PSANPHAKPT DFDFLKVIGK GSFGKVLLAK RKRDGKCYAI 180

KVLQKKVILN RREQKHIMAE RNVLLKNVKH PFLVGLHYSF QTTDKLYFVL DFVNGGELFF 240

HLQKERTFPE PRAKFYIAEM ASALGYLHSL NIVYRDLKPE NILLDSQGHI VLTDFGLCKE 300

GISQADTTTT FCGTPEYLAP EVLRKQPYDN TVDWWCLGSV LYEMLYGLPP FYSRDTHEMY 360

DNILHKELVM RPGASTAAWS ILQTLLEKDH TRRLGYRDDF NEVKEHEFFS SINWYDLEQK 420

KLSPPFNPSV ESQYDISNFD PEFTEETVPN SVCFSSGPSI VNASVMEADD AFLGFSYAPP 480

SEDSFL 486

Nucleotide Sequence
(FASTA)

ATGGAAGAGC AACCTAGCTG TCCCAATGTT AGCATTCCAT GCTATAATGA GCAGAGGGAC 60

AAGAAGAAAC GCTATACTGT TTACAAAGTT ATGGTCAGTG TTGGAAGGCA TGAGTGGTTT 120

GTGTTCCGGA GATATGCAGA ATTTGACAAA TTGTACAACA CGTTGAAAAA ACAATTTCCT 180

GCGCTGAATT TGAAGATTCC TGCTAAGAGA ATATTTGGCG ACAATTTTGA CCCAGAGTTT 240

ATAAAACAGA GACGAGCGGG GTTACATGAG TTCATTCAGA GGATCGTGTC CCATTCACAG 300

CTCTGCAGCC ATCCCGATGT CAAAGTCTTT CTGCAGATGG ACAAAGCCAA AAACTTCTCT 360

GATGGCTCAG AGGATGAAGA CGACAAGAGT AACTCTACCT CTAGAAACAT TAACCTGGGG 420

CCATCTGCAA ATCCACATGC AAAGCCCACT GACTTTGACT TTCTTAAAGT CATAGGAAAG 480

GGAAGCTTTG GGAAGGTTCT CCTTGCAAAG AGGAAACGGG ATGGGAAGTG TTATGCCATC 540

AAAGTCTTGC AAAAAAAGGT CATTCTAAAC AGGAGAGAGC AAAAGCACAT CATGGCTGAG 600

CGCAATGTGT TGCTGAAGAA TGTTAAACAC CCCTTCCTGG TTGGCCTGCA CTATTCCTTT 660

CAGACAACGG ACAAGCTATA CTTTGTTCTG GATTTTGTCA ATGGTGGAGA ACTTTTCTTT 720

CATCTCCAAA AAGAGCGGAC CTTTCCTGAA CCCAGAGCAA AGTTTTATAT TGCGGAGATG 780

GCGAGCGCTC TGGGTTACTT GCACTCTCTT AACATTGTTT ACAGGGATTT AAAACCAGAA 840

AATATCCTGC TGGACTCTCA AGGCCATATA GTCTTGACTG ACTTTGGACT GTGTAAGGAG 900

GGCATCTCTC AAGCAGACAC AACAACCACA TTTTGTGGAA CACCTGAGTA TCTAGCTCCA 960

GAAGTACTCA GGAAACAACC CTATGATAAC ACTGTGGACT GGTGGTGTCT GGGTTCCGTG 1020

CTGTATGAAA TGCTTTATGG ACTGCCTCCG TTCTACAGCA GGGACACGCA TGAGATGTAT 1080

GACAACATTC TTCACAAGGA GCTTGTCATG CGGCCCGGGG CGTCCACAGC TGCGTGGTCC 1140

ATCCTTCAGA CCCTGCTGGA GAAAGACCAC ACCAGGAGGC TTGGCTACAG AGATGACTTT 1200

AATGAAGTCA AAGAACATGA ATTTTTCTCA TCTATTAACT GGTATGACCT TGAACAGAAA 1260

AAGCTTTCTC CTCCATTTAA CCCTAGTGTG GAATCCCAGT ATGACATCTC AAACTTTGAT 1320

CCAGAGTTTA CAGAGGAAAC CGTGCCAAAC TCTGTGTGCT TCTCATCAGG GCCGTCGATC 1380

GTCAATGCGA GTGTCATGGA AGCGGACGAT GCCTTTCTGG GATTTTCTTA CGCTCCGCCA 1440

TCAGAAGATT CTTTCTTGTA A 1461

Domain Profile

S: 1     fdflkvigkgsfgkvllakrkadekfyavkvlqkkailkkkeekhimaernvllknvkhp  60

         fdflkvigkgsfgkvllakrk d+k ya+kvlqkk il+++e+khimaernvllknvkhp

Q: 152   FDFLKVIGKGSFGKVLLAKRKRDGKCYAIKVLQKKVILNRREQKHIMAERNVLLKNVKHP  211

         9***********************************************************

S: 61    flvglhysfqtaeklyfvldyvnggelffhlqrersfleprarfyaaeiasalgylhsln  120

         flvglhysfqt++klyfvld+vnggelffhlq+er+f+epra+fy ae+asalgylhsln

Q: 212   FLVGLHYSFQTTDKLYFVLDFVNGGELFFHLQKERTFPEPRAKFYIAEMASALGYLHSLN  271

         ************************************************************

S: 121   ivyrdlkpenilldskghvvltdfglckeeieaedttstfcgtpeylapevlrkkpydrt  180

         ivyrdlkpenillds+gh+vltdfglcke+i + dtt+tfcgtpeylapevlrk+pyd+t

Q: 272   IVYRDLKPENILLDSQGHIVLTDFGLCKEGISQADTTTTFCGTPEYLAPEVLRKQPYDNT  331

         ************************************************************

S: 181   vdwwclgavlyemlyglppfysrdvaemydnilnkplqlkpgisvaalelleellekdrk  240

         vdwwclg+vlyemlyglppfysrd+ emydnil+k l ++pg s+aa+++l++llekd++

Q: 332   VDWWCLGSVLYEMLYGLPPFYSRDTHEMYDNILHKELVMRPGASTAAWSILQTLLEKDHT  391

         ************************************************************

S: 241   krlgakedfleiknhvff  258

         +rlg ++df e+k+h ff

Q: 392   RRLGYRDDFNEVKEHEFF  409

         *****************9

Domain Sequence
(FASTA)

FDFLKVIGKG SFGKVLLAKR KRDGKCYAIK VLQKKVILNR REQKHIMAER NVLLKNVKHP 60

FLVGLHYSFQ TTDKLYFVLD FVNGGELFFH LQKERTFPEP RAKFYIAEMA SALGYLHSLN 120

IVYRDLKPEN ILLDSQGHIV LTDFGLCKEG ISQADTTTTF CGTPEYLAPE VLRKQPYDNT 180

VDWWCLGSVL YEMLYGLPPF YSRDTHEMYD NILHKELVMR PGASTAAWSI LQTLLEKDHT 240

RRLGYRDDFN EVKEHEFF 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0035091	; F:phosphatidylinositol binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007154	; P:cell communication

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR001683	; Phox.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.
PF00787	; PX; 1.

SMARTs

SM00312	; PX; 1.
SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.
PS50195	; PX; 1.

Prints

Created Date

20-Feb-2013