EPS-DAR-00052

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-DAR-00052

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	227.5	4.7E-67	93	349	257

Status

Unreviewed

Ensembl Protein

ENSDARP00000086614

UniProt Accession

A0JMP2;

Protein Name

Protein Synonyms/Alias

Novel protein similar to human and mouse protein phosphatase 1 (Formerly 2C)-like (PPM1L, zgc:154091); Zgc:154091;

Gene Name

ppm1la

Gene Synonyms/Alias

ppm1la; DKEY-119F1.3; DKEY-119F1.3-001;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDARG00000063218	ENSDARP00000086614	ENSDART00000092182

Organism

Danio rerio

Functional Description

Protein Length

361

Protein Sequence
(FASTA)

MIGDTMTLLS LLGRIMRYFL LRPETLFLLC ISLALWSYFF HTDEVKTIVK SSRDAVKMVK 60

GKVAEMMMND RLGGLDVLDA EFSKTWEFKN NNVAVYSIQG RRDHMEDRFE VLTDLANRSH 120

PSIFAIFDGH GGEGAADYVK AHLPEALKQQ LQAFEREKKD SPLSYPSILE QRILAVDRDM 180

VEKFSASHDE AGTTCLIALL SDRELTVANV GDSRGVLCDK DGNAVALSHD HKPYQLKERK 240

RIKRAGGFIS FNGSWRVQGI LAMSRSLGDY PLKNLNVVIP DPDILTFDLD KLQPEFMILA 300

SDGLWDAFSN EEAVRFVRER LDEPHFGAKS IVLQSFYRGC PDNITVMVVK FKSSSASKTA 360

E 361

Nucleotide Sequence
(FASTA)

ATGATAGGAG ACACAATGAC GCTTTTGTCT CTTTTGGGTC GCATCATGCG TTATTTCTTG 60

CTCAGGCCAG AGACCTTGTT TCTGTTATGC ATCAGCTTGG CCCTCTGGAG CTACTTCTTC 120

CACACGGACG AGGTGAAAAC CATCGTCAAG TCGAGCCGGG ATGCCGTGAA GATGGTGAAG 180

GGGAAAGTGG CGGAGATGAT GATGAACGAC AGGCTCGGCG GGCTGGACGT GCTGGACGCG 240

GAGTTCTCCA AGACCTGGGA GTTCAAGAAC AACAATGTGG CGGTGTACTC GATACAGGGC 300

CGGAGAGACC ACATGGAGGA CCGCTTCGAG GTGCTCACCG ACCTGGCCAA CAGGAGCCAC 360

CCTTCAATCT TTGCTATTTT TGACGGACAT GGTGGAGAGG GGGCTGCAGA TTATGTGAAA 420

GCCCACCTGC CGGAGGCTCT AAAGCAGCAG CTGCAGGCGT TCGAGAGGGA GAAGAAGGAC 480

AGTCCTCTCT CCTACCCCTC CATCCTGGAG CAGCGCATCC TGGCCGTGGA CCGGGACATG 540

GTGGAGAAGT TCTCTGCTTC TCATGATGAA GCAGGCACAA CATGTCTGAT AGCCTTGCTG 600

TCTGACCGCG AGCTGACTGT GGCGAATGTT GGAGACTCTC GTGGCGTTCT CTGCGATAAA 660

GATGGAAATG CTGTAGCCCT CTCGCACGAT CACAAGCCCT ACCAGCTGAA GGAGCGCAAG 720

AGGATCAAGA GAGCAGGAGG CTTCATCAGT TTCAACGGTT CATGGCGTGT GCAGGGCATC 780

CTGGCCATGT CTCGCTCACT AGGCGACTAC CCACTGAAAA ACCTGAACGT GGTCATCCCA 840

GACCCCGACA TCCTGACCTT CGACCTGGAC AAGCTGCAGC CCGAGTTCAT GATCCTGGCG 900

TCAGACGGCC TGTGGGACGC CTTCAGCAAC GAGGAGGCCG TGCGCTTCGT CCGGGAGCGT 960

CTAGACGAGC CGCACTTCGG CGCCAAGAGC ATCGTCCTGC AGTCGTTCTA CCGCGGCTGT 1020

CCAGACAACA TCACCGTCAT GGTGGTCAAG TTCAAGAGCA GCTCGGCCAG CAAAACTGCA 1080

GAGTAG 1086

Domain Profile

S: 3     vgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheila  62

         v v+s++grr++med++++ +++++++      ++f+++DGhgg+ +a++++ +l e+l+

Q: 93    VAVYSIQGRRDHMEDRFEVLTDLANRSHP----SIFAIFDGHGGEGAADYVKAHLPEALK  148

         6789***************9999999876....69*************************

S: 63    eele....sseseerkvk....kalakaFlstdeelkvleeksldidksGstavvalikd  114

         ++l+    +++++         ++l++  l++d+++  +e+ s ++d+ G+t+++al++d

Q: 149   QQLQaferEKKDS----PlsypSILEQRILAVDRDM--VEKFSASHDEAGTTCLIALLSD  202

         ****554434444....24466**************..9999999***************

S: 115   sklyvanvGdSravLcr.ngkavelssdHkpsredEleRieeaggsvilkdga.RvlGvL  172

          +l+vanvGdSr vLc+ +g+av+ls dHkp + +E++Ri++agg +  + g  Rv+G L

Q: 203   RELTVANVGDSRGVLCDkDGNAVALSHDHKPYQLKERKRIKRAGGFISFN-GSwRVQGIL  261

         *****************566************************999977.667******

S: 173   avsRalGdlylk..pyvtpePevtshrltsede.fliLasDGlwdvvsneeavslvrdvl  229

         a+sR+lGd+ lk   +v+p+P++  ++l++ +  f+iLasDGlwd +sneeav++vr++l

Q: 262   AMSRSLGDYPLKnlNVVIPDPDILTFDLDKLQPeFMILASDGLWDAFSNEEAVRFVRERL  321

         ************8889************765544**************************

S: 230   ekkeaeqeaakkLvklalargskdnvsaivv  260

         +   ++   ak++v ++  rg+ dn++++vv

Q: 322   D---EPHFGAKSIVLQSFYRGCPDNITVMVV  349

         *...999********************9997

Domain Sequence
(FASTA)

VAVYSIQGRR DHMEDRFEVL TDLANRSHPS IFAIFDGHGG EGAADYVKAH LPEALKQQLQ 60

AFEREKKDSP LSYPSILEQR ILAVDRDMVE KFSASHDEAG TTCLIALLSD RELTVANVGD 120

SRGVLCDKDG NAVALSHDHK PYQLKERKRI KRAGGFISFN GSWRVQGILA MSRSLGDYPL 180

KNLNVVIPDP DILTFDLDKL QPEFMILASD GLWDAFSNEE AVRFVRERLD EPHFGAKSIV 240

LQSFYRGCPD NITVMVV 257

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>